Page last updated: 2024-10-19

nitrates and Dementia

nitrates has been researched along with Dementia in 9 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"In older adults with dementia, OH-related syncopal falls are significantly related to treatment with nitrates, combinations of ACE-Is and diuretics, and combinations of ACE-Is and nitrates."3.88Hypotensive Drugs and Syncope Due to Orthostatic Hypotension in Older Adults with Dementia (Syncope and Dementia Study). ( Abete, P; Bellelli, G; Bo, M; Ceccofiglio, A; Curcio, F; Landi, F; Martone, AM; Mussi, C; Nicosia, F; Noro, G; Riccio, D; Testa, G; Ungar, A, 2018)
"The imitative dementia rats modle were established using health male Wistar rats by intraperitoneal injection of D-galactose and NaNO2, simultaneity, administer physiological saline solution, Piracetam Tablets, low dose grape peel extracts, middle dose grape peel extracts, high dose grape peel extracts to intervene separately."3.73[Anti-dementia effects of grape peel extracts experiment study]. ( Hong, Y; Long, MS; Yang, Y; Zhou, XH, 2006)
"Dementia is a significant public health priority with approximately 55 million cases worldwide, and this number is predicted to quadruple by 2050."2.82Dietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention? ( Alharbi, M; Babateen, A; Shannon, O; Siervo, M; Stephan, B, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Siervo, M1
Babateen, A1
Alharbi, M1
Stephan, B1
Shannon, O1
Carballo-Casla, A1
Dunk, MM1
Donat-Vargas, C1
Xu, W1
Testa, G1
Ceccofiglio, A1
Mussi, C1
Bellelli, G1
Nicosia, F1
Bo, M1
Riccio, D1
Curcio, F1
Martone, AM1
Noro, G1
Landi, F1
Ungar, A1
Abete, P1
Singh, G1
Sharma, B2
Jaggi, AS2
Singh, N2
Kumar, A1
Sodhi, RK1
Jain, S1
Long, MS1
Hong, Y1
Zhou, XH1
Yang, Y1
Kuiper, MA1
Visser, JJ1
Bergmans, PL1
Scheltens, P1
Wolters, EC1
Judge, TG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Testing the Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function in Older Adults Living With Overweight or Obesity: A 28-Day Pilot Randomised Trial[NCT06151015]20 participants (Anticipated)Interventional2024-01-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for nitrates and Dementia

ArticleYear
Dietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention?
    The British journal of nutrition, 2022, 09-28, Volume: 128, Issue:6

    Topics: Brain; Cardiovascular Diseases; Dementia; Diet; Humans; Nitrates; Nitric Oxide; Nitrites

2022
Vasodilators..
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenergic alpha-Antagonists; Aminophylline; Angina Pectoris; Bradycardia; Bronchial Diseases; Cereb

1974

Other Studies

7 other studies available for nitrates and Dementia

ArticleYear
Could dietary nitrate affect dementia development?
    The American journal of clinical nutrition, 2023, Volume: 118, Issue:2

    Topics: Dementia; Diet; Dietary Supplements; Humans; Nitrates; Nitrites

2023
Hypotensive Drugs and Syncope Due to Orthostatic Hypotension in Older Adults with Dementia (Syncope and Dementia Study).
    Journal of the American Geriatrics Society, 2018, Volume: 66, Issue:8

    Topics: Accidental Falls; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensiv

2018
Efficacy of bosentan, a dual ETA and ETB endothelin receptor antagonist, in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 124

    Topics: Acetylcholinesterase; Animals; Blood Glucose; Bosentan; Brain; Dementia; Diabetes Mellitus, Experime

2014
Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:8

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Cholesterol; Dementia; Diet, High-Fat; Disease Mo

2014
Effect of ruthenium red, a ryanodine receptor antagonist in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
    Physiology & behavior, 2016, 10-01, Volume: 164, Issue:Pt A

    Topics: Animals; Aorta; Blood Glucose; Body Weight; Brain; Calcium Channel Blockers; Dementia; Diabetes Mell

2016
[Anti-dementia effects of grape peel extracts experiment study].
    Wei sheng yan jiu = Journal of hygiene research, 2006, Volume: 35, Issue:3

    Topics: Animals; Dementia; Free Radical Scavengers; Galactose; Male; Neuroprotective Agents; Nitrates; Plant

2006
Decreased cerebrospinal fluid nitrate levels in Parkinson's disease, Alzheimer's disease and multiple system atrophy patients.
    Journal of the neurological sciences, 1994, Volume: 121, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Dementia; Female; Humans; Male; Middle Aged; Nerve Degeneration; N

1994