nitrates has been researched along with Colorectal Cancer in 25 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU), a known cardiotoxin, is the backbone for the treatment of colorectal cancer." | 8.12 | Managing life-threatening 5-fluorouracil cardiotoxicity. ( Boldig, K; Ganguly, A; Kadakia, M; Rohatgi, A, 2022) |
| "5-Fluorouracil, a widely used drug in cancer treatment, is known to have cardiotoxic effects: chest pain with ECG changes, arrhythmias, arterial hypertension or hypotension, myocardial infarction, cardiogenic shock and sudden death have been described in the literature." | 7.72 | Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases. ( Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B, 2003) |
| "5-Fluorouracil (5-FU), a known cardiotoxin, is the backbone for the treatment of colorectal cancer." | 4.12 | Managing life-threatening 5-fluorouracil cardiotoxicity. ( Boldig, K; Ganguly, A; Kadakia, M; Rohatgi, A, 2022) |
| "5-Fluorouracil, a widely used drug in cancer treatment, is known to have cardiotoxic effects: chest pain with ECG changes, arrhythmias, arterial hypertension or hypotension, myocardial infarction, cardiogenic shock and sudden death have been described in the literature." | 3.72 | Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases. ( Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B, 2003) |
| " Here we studied human colorectal adenocarcinomas and adenomas to determine whether oxidative stress is imposed on cancer cells in vivo and used specific antibodies against 8-hydroxy-2'-deoxyguanosine (8-OHdG), 4-hydroxy-2-nonenal (HNE)-modified proteins, and 3-nitro-L-tyrosine (3-NT) to determine whether there is an association between oxidative stress and cellular proliferation." | 3.70 | Persistent oxidative stress in human colorectal carcinoma, but not in adenoma. ( Hiai, H; Imamura, M; Iwasa, Y; Kondo, S; Onodera, H; Tanaka, T; Toyokuni, S, 1999) |
| "The risk of colorectal cancer (n = 6,640) increased by 35% for each 50 g/1,000 kcal higher daily intake of total red meat, with a significant right-to-left trend from proximal colon (HR: 1." | 2.87 | Anatomical subsite can modify the association between meat and meat compounds and risk of colorectal adenocarcinoma: Findings from three large US cohorts. ( Abnet, CC; Beane-Freeman, L; Dawsey, SM; Etemadi, A; Freedman, ND; Graubard, BI; Liao, L; Sinha, R, 2018) |
| " Therefore, we performed a dose-response meta-analysis of observational studies." | 2.72 | Nitrate-nitrite exposure through drinking water and diet and risk of colorectal cancer: A systematic review and meta-analysis of observational studies. ( Djafarian, K; Hosseini, F; Majdi, M; Naghshi, S; Shab-Bidar, S; Sheikhhossein, F, 2021) |
| "Obesity is a risk factor for the development of human colorectal cancer (CC)." | 1.43 | Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer. ( Amor, S; Barrios, V; Fernandez, N; Ferrero, E; García-Villalón, AL; García-Villar, O; Granado, M; Iglesias-de la Cruz, MC; Monge, L, 2016) |
| "We aimed to evaluate the risk of colorectal cancer (CRC) associated with nitrate exposure in drinking water and diet." | 1.43 | Colorectal cancer risk and nitrate exposure through drinking water and diet. ( Aggazzotti, G; Altzibar, JM; Aragonés, N; Ardanaz, E; Basagaña, X; Boldo, E; Bosetti, C; Burgui, R; Castaño-Vinyals, G; Espejo-Herrera, N; Fernández, T; Fernández-Tardón, G; Gómez Acebo, I; Gràcia-Lavedan, E; Kogevinas, M; La Vecchia, C; Martín, V; Molina, AJ; Moreno, V; Navarro, C; Nieuwenhuijsen, M; Peiró, R; Pérez-Gómez, B; Pisa, F; Polesel, J; Pollán, M; Righi, E; Serraino, D; Tardón, A; Tavani, A; Villanueva, CM, 2016) |
| "In the pooled analyses, an overall colorectal cancer risk was not observed for exposure to nitrate-nitrogen in the highest category (> or =10 ppm) compared to the lowest category (<0." | 1.35 | Nitrogen-nitrate exposure from drinking water and colorectal cancer risk for rural women in Wisconsin, USA. ( Bersch, AJ; Gangnon, RE; Hampton, JM; Kanarek, MS; McElroy, JA; Newcomb, PA; Trentham-Dietz, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chambers, T | 2 |
| Hales, S | 2 |
| Anglemyer, A | 1 |
| Boldig, K | 1 |
| Ganguly, A | 1 |
| Kadakia, M | 1 |
| Rohatgi, A | 1 |
| Grout, L | 1 |
| Prickett, M | 1 |
| Baker, MG | 1 |
| Wilson, N | 1 |
| Jacobsen, BH | 1 |
| Hansen, B | 2 |
| Schullehner, J | 2 |
| Alcolea, JA | 1 |
| Donat-Vargas, C | 1 |
| Chatziioannou, AC | 1 |
| Keski-Rahkonen, P | 1 |
| Robinot, N | 1 |
| Molina, AJ | 2 |
| Amiano, P | 1 |
| Gómez-Acebo, I | 1 |
| Castaño-Vinyals, G | 2 |
| Maitre, L | 1 |
| Chadeau-Hyam, M | 1 |
| Dagnino, S | 1 |
| Cheng, SL | 1 |
| Scalbert, A | 1 |
| Vineis, P | 1 |
| Kogevinas, M | 2 |
| Villanueva, CM | 2 |
| Hosseini, F | 1 |
| Majdi, M | 1 |
| Naghshi, S | 1 |
| Sheikhhossein, F | 1 |
| Djafarian, K | 1 |
| Shab-Bidar, S | 1 |
| Nasseri Maleki, G | 1 |
| Bayati Khatibi, M | 1 |
| Khamnian, Z | 1 |
| Jalali, Z | 1 |
| Dastgiri, S | 1 |
| Ghodrati Aroogh, H | 1 |
| Kobayashi, J | 1 |
| Thygesen, M | 1 |
| Pedersen, CB | 1 |
| Sigsgaard, T | 1 |
| Etemadi, A | 1 |
| Abnet, CC | 1 |
| Graubard, BI | 1 |
| Beane-Freeman, L | 1 |
| Freedman, ND | 1 |
| Liao, L | 1 |
| Dawsey, SM | 1 |
| Sinha, R | 2 |
| Temkin, A | 1 |
| Evans, S | 1 |
| Manidis, T | 1 |
| Campbell, C | 1 |
| Naidenko, OV | 1 |
| Miller, PE | 1 |
| Lazarus, P | 1 |
| Lesko, SM | 1 |
| Cross, AJ | 2 |
| Laio, J | 1 |
| Zhu, J | 1 |
| Harper, G | 1 |
| Muscat, JE | 1 |
| Hartman, TJ | 1 |
| Dellavalle, CT | 1 |
| Xiao, Q | 1 |
| Yang, G | 1 |
| Shu, XO | 1 |
| Aschebrook-Kilfoy, B | 1 |
| Zheng, W | 1 |
| Lan Li, H | 1 |
| Ji, BT | 1 |
| Rothman, N | 1 |
| Chow, WH | 1 |
| Gao, YT | 1 |
| Ward, MH | 1 |
| Amor, S | 1 |
| Iglesias-de la Cruz, MC | 1 |
| Ferrero, E | 1 |
| García-Villar, O | 1 |
| Barrios, V | 1 |
| Fernandez, N | 1 |
| Monge, L | 1 |
| García-Villalón, AL | 1 |
| Granado, M | 1 |
| Espejo-Herrera, N | 1 |
| Gràcia-Lavedan, E | 1 |
| Boldo, E | 1 |
| Aragonés, N | 1 |
| Pérez-Gómez, B | 1 |
| Pollán, M | 1 |
| Fernández, T | 1 |
| Martín, V | 1 |
| La Vecchia, C | 1 |
| Bosetti, C | 1 |
| Tavani, A | 1 |
| Polesel, J | 1 |
| Serraino, D | 1 |
| Gómez Acebo, I | 1 |
| Altzibar, JM | 1 |
| Ardanaz, E | 1 |
| Burgui, R | 1 |
| Pisa, F | 1 |
| Fernández-Tardón, G | 1 |
| Tardón, A | 1 |
| Peiró, R | 1 |
| Navarro, C | 1 |
| Moreno, V | 1 |
| Righi, E | 1 |
| Aggazzotti, G | 1 |
| Basagaña, X | 1 |
| Nieuwenhuijsen, M | 1 |
| Fachiroh, J | 1 |
| Gravitiani, E | 1 |
| Husodo, AH | 1 |
| McElroy, JA | 1 |
| Trentham-Dietz, A | 1 |
| Gangnon, RE | 1 |
| Hampton, JM | 1 |
| Bersch, AJ | 1 |
| Kanarek, MS | 1 |
| Newcomb, PA | 1 |
| Pollock, JR | 1 |
| Bingham, SA | 1 |
| Akbulut, H | 1 |
| Altuntas, F | 1 |
| Akbulut, KG | 1 |
| Ozturk, G | 1 |
| Cindoruk, M | 1 |
| Unal, E | 1 |
| Icli, F | 1 |
| Mafrici, A | 1 |
| Alberti, A | 1 |
| Corrada, E | 1 |
| Ferrari, S | 1 |
| Marenna, B | 1 |
| Cianchi, F | 1 |
| Cortesini, C | 1 |
| Fantappiè, O | 1 |
| Messerini, L | 1 |
| Sardi, I | 1 |
| Lasagna, N | 1 |
| Perna, F | 1 |
| Fabbroni, V | 1 |
| Di Felice, A | 1 |
| Perigli, G | 1 |
| Mazzanti, R | 1 |
| Masini, E | 1 |
| Knekt, P | 1 |
| Järvinen, R | 1 |
| Dich, J | 1 |
| Hakulinen, T | 1 |
| Kondo, S | 2 |
| Toyokuni, S | 2 |
| Iwasa, Y | 1 |
| Tanaka, T | 1 |
| Onodera, H | 2 |
| Hiai, H | 2 |
| Imamura, M | 2 |
| Szaleczky, E | 1 |
| Prónai, L | 1 |
| Nakazawa, H | 1 |
| Tulassay, Z | 1 |
| Tsuruyama, T | 1 |
| Ozeki, M | 1 |
| Tachibana, T | 1 |
| Echizenya, M | 1 |
3 reviews available for nitrates and Colorectal Cancer
| Article | Year |
|---|---|
Nitrate-nitrite exposure through drinking water and diet and risk of colorectal cancer: A systematic review and meta-analysis of observational studies.
Topics: Colorectal Neoplasms; Diet; Drinking Water; Humans; Nitrates; Nitrites; Risk Assessment | 2021 |
Effect of diet and gut environment on the gastrointestinal formation of N-nitroso compounds: A review.
Topics: Colon; Colorectal Neoplasms; Diet; Dysbiosis; Esophagus; Humans; Inflammatory Bowel Diseases; Nitrat | 2018 |
Exposure-based assessment and economic valuation of adverse birth outcomes and cancer risk due to nitrate in United States drinking water.
Topics: Adult; Colorectal Neoplasms; Drinking Water; Female; Humans; Infant, Newborn; Nitrates; Nitrogen Oxi | 2019 |
2 trials available for nitrates and Colorectal Cancer
| Article | Year |
|---|---|
Anatomical subsite can modify the association between meat and meat compounds and risk of colorectal adenocarcinoma: Findings from three large US cohorts.
Topics: Adenocarcinoma; Aged; Cohort Studies; Colorectal Neoplasms; Diet; Female; Follow-Up Studies; Heteroc | 2018 |
Red meat and colorectal cancer risk: the effect of dietary iron and haem on endogenous N-nitrosation.
Topics: Adult; Aged; Animals; Cattle; Colorectal Neoplasms; Cross-Over Studies; Feces; Heme; Humans; Iron, D | 2002 |
20 other studies available for nitrates and Colorectal Cancer
| Article | Year |
|---|---|
Letter to the editor: Correction "Nitrate-nitrite exposure through drinking water and diet and risk of colorectal cancer: A systematic review and meta-analysis of observational studies".
Topics: Colorectal Neoplasms; Diet; Drinking Water; Humans; Nitrates; Nitrites | 2021 |
Managing life-threatening 5-fluorouracil cardiotoxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium Channel Blockers; Camptothecin; Cardiotoxici | 2022 |
The potential human health hazard of nitrates in drinking water: a media discourse analysis in a high-income country.
Topics: Colorectal Neoplasms; COVID-19; Drinking Water; Humans; Nitrates; Pandemics | 2023 |
Health-economic valuation of lowering nitrate standards in drinking water related to colorectal cancer in Denmark.
Topics: Colorectal Neoplasms; Denmark; Drinking Water; Humans; Nitrates; Water Pollutants, Chemical | 2024 |
Metabolomic Signatures of Exposure to Nitrate and Trihalomethanes in Drinking Water and Colorectal Cancer Risk in a Spanish Multicentric Study (MCC-Spain).
Topics: Colorectal Neoplasms; Drinking Water; Humans; Nitrates; Spain; Trihalomethanes; Water Pollutants, Ch | 2023 |
Association between nitrate concentration in drinking water and rate of colorectal cancer: a case study in northwestern Iran.
Topics: Colorectal Neoplasms; Drinking Water; Female; Humans; Incidence; Iran; Male; Nitrates; Water Supply | 2022 |
Nitrate in drinking water and colorectal cancer risk: A nationwide population-based cohort study.
Topics: Cohort Studies; Colorectal Neoplasms; Denmark; Drinking Water; Female; Humans; Male; Nitrates; Regis | 2018 |
Meat-related compounds and colorectal cancer risk by anatomical subsite.
Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cookin | 2013 |
Dietary nitrate and nitrite intake and risk of colorectal cancer in the Shanghai Women's Health Study.
Topics: Adult; Aged; Ascorbic Acid; Cell Transformation, Neoplastic; China; Colorectal Neoplasms; Diet; Feed | 2014 |
Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Body Mass Index; Colorectal Neoplasms; Cyclooxygenase 2 Inh | 2016 |
Colorectal cancer risk and nitrate exposure through drinking water and diet.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; Diet; Drinking Water; En | 2016 |
Nitrate in drinking water and risk of colorectal cancer in Yogyakarta, Indonesia.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; Drinking Water; Female; | 2017 |
Nitrogen-nitrate exposure from drinking water and colorectal cancer risk for rural women in Wisconsin, USA.
Topics: Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Drinking; Environmental Exposure; Female; F | 2008 |
Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2002 |
Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antimetabolites, Antineoplas | 2003 |
Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer.
Topics: Aged; Aged, 80 and over; Amidines; Arachidonic Acid; Benzylamines; Blotting, Northern; Blotting, Wes | 2004 |
Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Beer; Carcinogens; Colorectal Neoplasms; Diet; | 1999 |
Persistent oxidative stress in human colorectal carcinoma, but not in adenoma.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Adenoma; Adult; Aged; Aldehydes; Case-Control Studies; | 1999 |
Evidence of in vivo peroxynitrite formation in patients with colorectal carcinoma, higher plasma nitrate/nitrite levels, and lower protection against oxygen free radicals.
Topics: Aged; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Oxidants; Reactiv | 2000 |
Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver.
Topics: Adenocarcinoma; Aged; Apoptosis; Cell Division; Colorectal Neoplasms; Female; Humans; Immunoenzyme T | 2002 |