Page last updated: 2024-10-19

nitrates and Chronic Primary Open Angle Glaucoma

nitrates has been researched along with Chronic Primary Open Angle Glaucoma in 10 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"To evaluate plasma total homocysteine (tHcy) and nitric oxide (NO) marker levels in patients with pseudoexfoliation syndrome (PXS), pseudoexfoliation glaucoma (PXG), primary open-angle glaucoma (POAG), and normal controls."7.73Homocysteine and nitric oxide levels in plasma of patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and primary open-angle glaucoma. ( Altintaş, O; Cağlar, Y; Dillioğlugil, MO; Karabaş, VL; Maral, H; Yüksel, N, 2005)
"To evaluate plasma total homocysteine (tHcy) and nitric oxide (NO) marker levels in patients with pseudoexfoliation syndrome (PXS), pseudoexfoliation glaucoma (PXG), primary open-angle glaucoma (POAG), and normal controls."3.73Homocysteine and nitric oxide levels in plasma of patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and primary open-angle glaucoma. ( Altintaş, O; Cağlar, Y; Dillioğlugil, MO; Karabaş, VL; Maral, H; Yüksel, N, 2005)
" Its Phase 3 pivotal clinical trials failed at the wrong dose and dosing regimen because of the misinterpretation of the complex IOP results from the Phase 2 monotherapy and combination studies."2.72Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data. ( Qiu, TG, 2021)
"Primary open angle glaucoma (POAG) is the most common type of glaucoma, and is responsible for approximately 90% of glaucoma cases in North America."1.46Current therapeutic options and treatments in development for the management of primary open-angle glaucoma. ( Lee, JK; Liebmann, JM, 2017)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Vergroesen, JE1
de Crom, TOE1
Blekkenhorst, LC1
Klaver, CCW1
Voortman, T1
Ramdas, WD1
Qiu, TG1
Liebmann, JM1
Lee, JK1
Emam, WA1
Zidan, HE1
Abdulhalim, BE1
Dabour, SA1
Ghali, MA1
Kamal, AT1
Xie, W1
Kang, JH1
Willett, WC1
Rosner, BA1
Buys, E1
Wiggs, JL1
Pasquale, LR1
Myers, JS1
Sall, KN1
DuBiner, H1
Slomowitz, N1
McVicar, W1
Rich, CC1
Baumgartner, RA1
Altintaş, O1
Maral, H1
Yüksel, N1
Karabaş, VL1
Dillioğlugil, MO1
Cağlar, Y1
Grunwald, JE1
DuPont, J1
Dreyer, EB1
Drance, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial Of The Effect Of Tropical Fruits On Intraocular Pressure And Retinal Nerve Fibre Layer Thickness In Patients With Primary Glaucoma[NCT06071494]102 participants (Anticipated)Interventional2023-10-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrates and Chronic Primary Open Angle Glaucoma

ArticleYear
Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data.
    Expert opinion on investigational drugs, 2021, Volume: 30, Issue:3

    Topics: Animals; Drug Delivery Systems; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Nitrates; Ocular

2021

Trials

2 trials available for nitrates and Chronic Primary Open Angle Glaucoma

ArticleYear
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2016, Volume: 32, Issue:8

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Fema

2016
Effect of chronic nitrate treatment on retinal vessel caliber in open-angle glaucoma.
    American journal of ophthalmology, 1997, Volume: 123, Issue:6

    Topics: Aged; Blood Flow Velocity; Cardiomyopathies; Disease Progression; Exfoliation Syndrome; Female; Glau

1997

Other Studies

7 other studies available for nitrates and Chronic Primary Open Angle Glaucoma

ArticleYear
Dietary Nitrate Intake Is Associated with Decreased Incidence of Open-Angle Glaucoma: The Rotterdam Study.
    Nutrients, 2022, Jun-15, Volume: 14, Issue:12

    Topics: Female; Glaucoma, Open-Angle; Humans; Incidence; Nitrates; Nitric Oxide; Nitrogen Oxides; Prospectiv

2022
Current therapeutic options and treatments in development for the management of primary open-angle glaucoma.
    The American journal of managed care, 2017, Volume: 23, Issue:15 Suppl

    Topics: Aqueous Humor; Benzoates; beta-Alanine; Cholinergic Agents; Glaucoma, Open-Angle; Humans; Intraocula

2017
Endothelial nitric oxide synthase polymorphisms and susceptibility to high-tension primary open-angle glaucoma in an Egyptian cohort.
    Molecular vision, 2014, Volume: 20

    Topics: Adult; Aged; Case-Control Studies; Cohort Studies; Demography; Egypt; Female; Gene Frequency; Geneti

2014
Nitrates are safe in patients with glaucoma.
    Medical hypotheses, 2015, Volume: 85, Issue:6

    Topics: Angina Pectoris; Comorbidity; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pre

2015
Association of Dietary Nitrate Intake With Primary Open-Angle Glaucoma: A Prospective Analysis From the Nurses' Health Study and Health Professionals Follow-up Study.
    JAMA ophthalmology, 2016, Volume: 134, Issue:3

    Topics: Adult; Aged; Diet; Feeding Behavior; Female; Follow-Up Studies; Glaucoma, Open-Angle; Health Personn

2016
Homocysteine and nitric oxide levels in plasma of patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and primary open-angle glaucoma.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2005, Volume: 243, Issue:7

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Exfoliation Syndrome; Female; Fluorescence Polariz

2005
Glaucoma: a look beyond intraocular pressure.
    American journal of ophthalmology, 1997, Volume: 123, Issue:6

    Topics: Blood Flow Velocity; Cardiomyopathies; Glaucoma, Open-Angle; Humans; Nitrates; Retinal Vessels; Vaso

1997