nitrates has been researched along with Chronic Lung Injury in 16 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Previously, we reported an increase in protein tyrosine nitration (a marker of oxidative/nitrosative damage) and a decrease in the antioxidant enzyme extracellular superoxide dismutase (EC-SOD) in the lungs of young mice during endotoxemia-induced SIRS." | 3.77 | The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation. ( Evers, BM; Saito, H; Starr, ME; Ueda, J; Yamamoto, S, 2011) |
| "This lung injury is mediated by peroxynitrite and is prevented by treatment with a peroxynitrite decomposition catalyst." | 1.42 | Chronic lung injury in the neonatal rat: up-regulation of TGFβ1 and nitration of IGF-R1 by peroxynitrite as likely contributors to impaired alveologenesis. ( Belcastro, R; Li, J; Lopez, L; Masood, A; Tanswell, AK, 2015) |
| "Acute lung injury was associated with a higher degree of pulmonary HIF-1α and iNOS expression as well as apoptosis in the lungs." | 1.38 | Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats. ( Hu, R; Huang, Y; Jiang, H; Li, QF; Xu, H, 2012) |
| "Smoke inhalation injury is often complicated with pneumonia, which frequently leads to subsequent development of sepsis." | 1.35 | Role of neuronal nitric oxide synthase in ovine sepsis model. ( Enkhbaatar, P; Hamahata, A; Herndon, D; Jaroch, S; Jonkam, C; Lange, M; Nakano, Y; Traber, D; Traber, L; Wang, J, 2009) |
| "Melatonin (MT) has direct and indirect free radical detoxifying activity." | 1.35 | Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia. ( Fu, JH; Pan, L; Wei, B; Xu, W; Xue, XD; Zhou, P, 2009) |
| "Burn and smoke inhalation injury was induced by standardized procedures, including a 40% area full thickness flame burn combined with 48 breaths of smoke from burning cottons." | 1.34 | L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep. ( Cox, RA; Enkhbaatar, P; Hawkins, HK; Herndon, D; Murakami, K; Tompkins, RG; Traber, DL; Traber, LD; Yu, YM, 2007) |
| "Acute lung injury is an important feature of sepsis and increased iNOS expression and NO production contribute to the pathogenesis of this syndrome." | 1.31 | Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia. ( Joseph, M; McCormack, DG; Mehta, S; Razavi, HM; Scott, JA; Wang, LF; Weicker, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Narala, VR | 1 |
| Thimmana, LV | 1 |
| Panati, K | 1 |
| Kolliputi, N | 1 |
| Fernandez-Bustamante, A | 1 |
| Klawitter, J | 1 |
| Repine, JE | 1 |
| Agazio, A | 1 |
| Janocha, AJ | 1 |
| Shah, C | 1 |
| Moss, M | 1 |
| Douglas, IS | 1 |
| Tran, ZV | 1 |
| Erzurum, SC | 1 |
| Christians, U | 1 |
| Seres, T | 1 |
| Belcastro, R | 1 |
| Lopez, L | 1 |
| Li, J | 1 |
| Masood, A | 1 |
| Tanswell, AK | 1 |
| Nader, MA | 1 |
| Wagih, HM | 1 |
| Hagiwara, S | 1 |
| Iwasaka, H | 1 |
| Togo, K | 1 |
| Noguchi, T | 1 |
| Enkhbaatar, P | 3 |
| Lange, M | 2 |
| Nakano, Y | 2 |
| Hamahata, A | 2 |
| Jonkam, C | 1 |
| Wang, J | 2 |
| Jaroch, S | 1 |
| Traber, L | 1 |
| Herndon, D | 2 |
| Traber, D | 1 |
| Shang, Y | 1 |
| Li, X | 1 |
| Prasad, PV | 1 |
| Xu, S | 1 |
| Yao, S | 1 |
| Liu, D | 1 |
| Yuan, S | 1 |
| Feng, D | 1 |
| Pan, L | 1 |
| Fu, JH | 1 |
| Xue, XD | 1 |
| Xu, W | 1 |
| Zhou, P | 1 |
| Wei, B | 1 |
| Saunders, FD | 1 |
| Westphal, M | 1 |
| Pazdrak, K | 1 |
| Jonkam, CC | 1 |
| Connelly, RL | 1 |
| Kulp, GA | 1 |
| Cox, RA | 2 |
| Hawkins, HK | 2 |
| Schmalstieg, FC | 1 |
| Horvath, E | 1 |
| Szabo, C | 1 |
| Traber, LD | 2 |
| Whorton, E | 1 |
| Herndon, DN | 1 |
| Traber, DL | 2 |
| Delbin, MA | 1 |
| Davel, AP | 1 |
| Rossoni, LV | 1 |
| Antunes, E | 1 |
| Zanesco, A | 1 |
| Starr, ME | 1 |
| Ueda, J | 1 |
| Yamamoto, S | 1 |
| Evers, BM | 1 |
| Saito, H | 1 |
| Jiang, H | 1 |
| Huang, Y | 1 |
| Xu, H | 1 |
| Hu, R | 1 |
| Li, QF | 1 |
| Abdelrahman, M | 1 |
| Mazzon, E | 1 |
| Bauer, M | 1 |
| Bauer, I | 1 |
| Delbosc, S | 1 |
| Cristol, JP | 1 |
| Patel, NS | 1 |
| Cuzzocrea, S | 1 |
| Thiemermann, C | 1 |
| Murakami, K | 1 |
| Yu, YM | 1 |
| Tompkins, RG | 1 |
| Zhu, S | 1 |
| Manuel, M | 1 |
| Tanaka, S | 1 |
| Choe, N | 1 |
| Kagan, E | 1 |
| Matalon, S | 1 |
| Wang, LF | 1 |
| Mehta, S | 1 |
| Weicker, S | 1 |
| Scott, JA | 1 |
| Joseph, M | 1 |
| Razavi, HM | 1 |
| McCormack, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Erythropoietin on Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome[NCT05857891] | 40 participants (Anticipated) | Interventional | 2023-05-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitrates and Chronic Lung Injury
| Article | Year |
|---|---|
Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury.
Topics: Animals; Asbestos; Gene Expression; Humans; Lung; Lung Injury; Nitrates; Nitric Oxide; Nitrogen; Rea | 1998 |
1 trial available for nitrates and Chronic Lung Injury
| Article | Year |
|---|---|
Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs.
Topics: Aged; Arthroplasty, Replacement, Knee; Biomarkers; Cytokines; Female; Humans; Lung Injury; Male; Mid | 2014 |
14 other studies available for nitrates and Chronic Lung Injury
| Article | Year |
|---|---|
Nitrated fatty acid, 10-nitrooleate protects against hyperoxia-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Antioxidants; COVID-19; Fatty Acids; Humans; Hyperoxia; Lung; Lung Injur | 2022 |
Chronic lung injury in the neonatal rat: up-regulation of TGFβ1 and nitration of IGF-R1 by peroxynitrite as likely contributors to impaired alveologenesis.
Topics: Animals; Animals, Newborn; Benzamides; Dioxoles; DNA; Epithelial Cells; Gene Expression Regulation; | 2015 |
Nilotinib, a tyrosine kinase inhibitor exhibits protection against acute pancreatitis-induced lung and liver damage in rats.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Biomarkers; Cyto | 2017 |
A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.
Topics: Animals; Glycine; HMGB1 Protein; Interleukin-6; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung | 2008 |
Role of neuronal nitric oxide synthase in ovine sepsis model.
Topics: Animals; Disease Models, Animal; Female; Hemodynamics; Interleukin-6; Lung; Lung Injury; Nitrates; N | 2009 |
Erythropoietin attenuates lung injury in lipopolysaccharide treated rats.
Topics: Animals; Erythropoietin; Lipopolysaccharides; Lung; Lung Injury; Male; Malondialdehyde; Nitrates; Ni | 2009 |
Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia.
Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Disease Models, Animal; Glutathione Peroxidase; H | 2009 |
Molecular biological effects of selective neuronal nitric oxide synthase inhibition in ovine lung injury.
Topics: Airway Obstruction; Animals; Cell Nucleus; Enzyme Activation; Hemodynamics; Indazoles; Interleukin-8 | 2010 |
Beneficial effects of physical training on the cardio-inflammatory disorder induced by lung ischemia/reperfusion in rats.
Topics: Animals; Interleukin-6; Lung Injury; Male; Mesenteric Arteries; NADPH Oxidases; Nitrates; Nitrites; | 2011 |
The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation.
Topics: Aging; Animals; Blotting, Western; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Endotoxem | 2011 |
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats.
Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cytoprotection; Disease Models, Animal; | 2012 |
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.
Topics: Acetophenones; Alanine Transaminase; Animals; Creatinine; DNA; Enzyme Inhibitors; Humans; Intestinal | 2005 |
L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep.
Topics: Airway Obstruction; Animals; Arginine; Blood Pressure; Burns; Female; Hematocrit; Lung; Lung Injury; | 2007 |
Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chimera; Endotoxemia; In Vitro Techniques; | 2001 |