nitrates has been researched along with Choline Deficiency in 3 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonalcoholic fatty liver disease is a chronic metabolic disorder with significant impact on cardiovascular and liver mortality." | 1.38 | Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. ( Bucchieri, F; Bugianesi, E; Galvano, F; Li Volti, G; Mangiameli, A; Marino Gammazza, A; Marino, A; Parola, M; Paternostro, C; Salamone, F; Tibullo, D, 2012) |
| "The pathogenesis of nonalcoholic steatohepatitis (NASH) is still unclear." | 1.36 | Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model. ( Fujita, K; Inamori, M; Iwasaki, T; Kirikoshi, H; Maeyama, S; Nakajima, A; Nozaki, Y; Saito, S; Takahashi, H; Terauchi, Y; Wada, K; Yoneda, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jorgačević, B | 1 |
| Mladenović, D | 1 |
| Ninković, M | 1 |
| Prokić, V | 1 |
| Stanković, MN | 1 |
| Aleksić, V | 1 |
| Cerović, I | 1 |
| Vukićević, RJ | 1 |
| Vučević, D | 1 |
| Stanković, M | 1 |
| Radosavljević, T | 1 |
| Fujita, K | 1 |
| Nozaki, Y | 1 |
| Yoneda, M | 1 |
| Wada, K | 1 |
| Takahashi, H | 1 |
| Kirikoshi, H | 1 |
| Inamori, M | 1 |
| Saito, S | 1 |
| Iwasaki, T | 1 |
| Terauchi, Y | 1 |
| Maeyama, S | 1 |
| Nakajima, A | 1 |
| Salamone, F | 1 |
| Galvano, F | 1 |
| Marino Gammazza, A | 1 |
| Marino, A | 1 |
| Paternostro, C | 1 |
| Tibullo, D | 1 |
| Bucchieri, F | 1 |
| Mangiameli, A | 1 |
| Parola, M | 1 |
| Bugianesi, E | 1 |
| Li Volti, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Dapagliflozin on Cardio-Metabolic Risk Factors in Patients With Type-2 Diabetes[NCT03377335] | Phase 4 | 186 participants (Anticipated) | Interventional | 2017-12-22 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for nitrates and Choline Deficiency
| Article | Year |
|---|---|
Dynamics of oxidative/nitrosative stress in mice with methionine-choline-deficient diet-induced nonalcoholic fatty liver disease.
Topics: Animals; Antioxidants; C-Reactive Protein; Catalase; Choline Deficiency; Disease Models, Animal; Fer | 2014 |
Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model.
Topics: Amino Acids; Animals; Blotting, Western; Choline; Choline Deficiency; Diet; Disease Models, Animal; | 2010 |
Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline Deficiency; Cytokines; Di | 2012 |