nitrates has been researched along with Cerebral Malaria in 10 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether iron chelation modulates nitric oxide (NO) formation and cell-mediated immune effector function in children with cerebral malaria, serum concentrations were measured of the stable end products of NO, nitrite and nitrate (NO2-/NO3-), interleukin (IL)-4, -6, and -10, and neopterin in 39 Zambian children enrolled in a placebo-controlled trial of desferrioxamine B and quinine therapy." | 5.08 | Modulatory potential of iron chelation therapy on nitric oxide formation in cerebral malaria. ( Gordeuk, VR; Herold, M; Mabeza, G; Thuma, PE; Weiss, G; Werner, ER, 1997) |
| "The pathogenesis of cerebral malaria is poorly understood." | 1.31 | Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism? ( Crawley, J; Dobbie, M; Marsh, K; Surtees, R; Waruiru, C, 2000) |
| "The main clinical presentations in cerebral malaria patients were fever (76." | 1.30 | Plasma levels of nitric oxide in association with severe Plasmodium falciparum in Yemen. ( Abd-Allah, SH; Agina, AA, 1999) |
| "Cerebral malaria is due to the immune response induced by the parasite, which results in an increased production of TNF, known to increase the expression of adhesion molecules on the endothelia." | 1.30 | Role of ICAM-1 (CD54) in the development of murine cerebral malaria. ( Da Laperousaz, C; Favre, N; Imhof, BA; Lucas, R; Piguet, PF; Rudin, W; Ryffel, B; Weiss, NA, 1999) |
| "Autoimmune disease is generally rare in tropical rural populations." | 1.29 | Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa? ( al-Yaman, FM; Clark, IA; Cowden, WB; Rockett, KA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhangadamajhi, G | 1 |
| Mohapatra, BN | 1 |
| Kar, SK | 1 |
| Ranjit, M | 1 |
| Agina, AA | 1 |
| Abd-Allah, SH | 1 |
| Cramer, JP | 1 |
| Nüssler, AK | 1 |
| Ehrhardt, S | 1 |
| Burkhardt, J | 1 |
| Otchwemah, RN | 1 |
| Zanger, P | 1 |
| Dietz, E | 1 |
| Gellert, S | 1 |
| Bienzle, U | 1 |
| Mockenhaupt, FP | 1 |
| Clark, IA | 2 |
| Cowden, WB | 2 |
| Rockett, KA | 2 |
| Asensio, VC | 1 |
| Oshima, H | 1 |
| Falanga, PB | 1 |
| al-Yaman, FM | 1 |
| Weiss, G | 1 |
| Thuma, PE | 1 |
| Mabeza, G | 1 |
| Werner, ER | 1 |
| Herold, M | 1 |
| Gordeuk, VR | 1 |
| Levesque, MC | 1 |
| Hobbs, MR | 1 |
| Anstey, NM | 1 |
| Vaughn, TN | 1 |
| Chancellor, JA | 1 |
| Pole, A | 1 |
| Perkins, DJ | 1 |
| Misukonis, MA | 1 |
| Chanock, SJ | 1 |
| Granger, DL | 1 |
| Weinberg, JB | 1 |
| Favre, N | 1 |
| Da Laperousaz, C | 1 |
| Ryffel, B | 1 |
| Weiss, NA | 1 |
| Imhof, BA | 1 |
| Rudin, W | 1 |
| Lucas, R | 1 |
| Piguet, PF | 1 |
| Dobbie, M | 1 |
| Crawley, J | 1 |
| Waruiru, C | 1 |
| Marsh, K | 1 |
| Surtees, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819] | 256 participants (Anticipated) | Observational | 2021-01-02 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nitrates and Cerebral Malaria
| Article | Year |
|---|---|
Modulatory potential of iron chelation therapy on nitric oxide formation in cerebral malaria.
Topics: Biopterins; Chelation Therapy; Child; Child, Preschool; Deferoxamine; Double-Blind Method; Humans; I | 1997 |
9 other studies available for nitrates and Cerebral Malaria
| Article | Year |
|---|---|
Endothelial nitric oxide synthase gene polymorphisms and Plasmodium falciparum infection in Indian adults.
Topics: Adult; Animals; Gene Frequency; Haplotypes; Humans; Immunity, Innate; India; Malaria; Malaria, Cereb | 2009 |
Plasma levels of nitric oxide in association with severe Plasmodium falciparum in Yemen.
Topics: Adolescent; Adult; Animals; Child; Female; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Mid | 1999 |
Age-dependent effect of plasma nitric oxide on parasite density in Ghanaian children with severe malaria.
Topics: Age Factors; Anemia; Animals; Child; Child, Preschool; Female; Genotype; Ghana; Humans; Infant; Mala | 2005 |
Nitric oxide in cerebral malaria.
Topics: Animals; Cameroon; Child; Coma; Diet; Humans; Malaria, Cerebral; Nitrates; Nitric Oxide; Nitrites | 1995 |
Plasmodium berghei: is nitric oxide involved in the pathogenesis of mouse cerebral malaria?
Topics: Animals; Arginine; Disease Susceptibility; Malaria, Cerebral; Mice; Mice, Inbred Strains; Nitrates; | 1993 |
Does malarial tolerance, through nitric oxide, explain the low incidence of autoimmune disease in tropical Africa?
Topics: Africa; Autoimmune Diseases; Humans; Immune Tolerance; Immunosuppression Therapy; Macrophages; Malar | 1996 |
Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria.
Topics: Alleles; Black People; Child; Child, Preschool; Gene Frequency; Humans; Infant; Malaria, Cerebral; M | 1999 |
Role of ICAM-1 (CD54) in the development of murine cerebral malaria.
Topics: Animals; Blood Platelets; Blood-Brain Barrier; Brain; Erythrocytes; Intercellular Adhesion Molecule- | 1999 |
Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?
Topics: Antimalarials; Biopterins; Brain; Child; Child, Preschool; Chromatography, High Pressure Liquid; End | 2000 |