Page last updated: 2024-10-19

nitrates and Cardiomyopathy, Dilated

nitrates has been researched along with Cardiomyopathy, Dilated in 18 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.

Research Excerpts

ExcerptRelevanceReference
"enalapril alone to enhance vascular effects, increase LV contractility and prevent unfavorable remodeling and are consistent with vascular delivery of exogenous NO."5.32A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. ( Condorelli, G; Del Soldato, P; Dieterle, T; Gu, Y; Iwanaga, Y; Ongini, E; Peterson, KL; Presotto, C; Ross, J, 2004)
"Dilated cardiomyopathy is characterized by elevated arterial vascular resistance and impaired nitric oxide (NO)-dependent vasodilation."2.69Role of nitric oxide in the vasodilator effect of recombinant human growth hormone in patients with dilated cardiomyopathy. ( Bit-Avragim, N; Bode-Böger, SM; Böger, RH; Dietz, R; Ellmer, AE; Hänlein, D; Osterziel, KJ; Ranke, MB; Strohm, O, 2000)
"enalapril alone to enhance vascular effects, increase LV contractility and prevent unfavorable remodeling and are consistent with vascular delivery of exogenous NO."1.32A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. ( Condorelli, G; Del Soldato, P; Dieterle, T; Gu, Y; Iwanaga, Y; Ongini, E; Peterson, KL; Presotto, C; Ross, J, 2004)
"The pathogenesis of dilated cardiomyopathy (DCM) is unknown, but clinical evidence suggests that coronary vasospasm is associated with the development of DCM in some cases."1.31Effects of anti-vasospastic agents in Japanese patients with dilated cardiomyopathy and coronary vasospasm. ( Fumikura, Y; Ilda, K; Kawano, S; Masumi, T; Nishi, I; Ohtsuka, S; Watanabe, S; Yamaguchi, I, 2002)
"Heart failure is associated with an increase in plasma nitrate and nitrite (NOx)."1.31Plasma nitrate accumulation during the development of pacing-induced dilated cardiac myopathy in conscious dogs is due to renal impairment. ( Hintze, TH; Laycock, S; Ochoa, M; Osorio, JC; Vogel, T; Xu, X, 2001)
"Investigation showed dilated cardiomyopathy without myocardial hypertrophy."1.30[Cardiomyopathy induced by catecholamines in neuroblastoma]. ( Brugières, L; Casasoprana, A; Joseph, T; Magnier, S; Olivier, B, 1997)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's3 (16.67)18.2507
2000's8 (44.44)29.6817
2010's2 (11.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Giam, B1
Nomura, H1
Kuruppu, S1
Chu, PY1
Essid, S1
Kiriazis, H1
Du, XJ1
Kaye, DM1
Rajapakse, NW1
Kerley, CP1
O'Neill, JO1
Reddy Bijjam, V1
Blaine, C1
James, PE1
Cormican, L1
Rogers, RJ1
Lang, W1
Barone Gibbs, B1
Davis, KK1
Burke, LE1
Kovacs, SJ1
Portzer, LA1
Jakicic, JM1
Notter, RH1
Gupta, R1
Schwan, AL1
Wang, Z1
Shkoor, MG1
Walther, FJ1
Zang, Q1
Zhou, L1
Zhuge, F1
Yang, H1
Wang, X1
Lin, X1
Lang, XY1
Liu, BT1
Shi, XM1
Li, YQ1
Wen, Z1
Jiang, Q1
Chen, D1
Xiong, X1
Zhao, B1
Mahmoud, MA1
El-Sayed, MA1
Liu, M1
Rotar, IC1
Dumitras, DE1
Popp, RA1
Petrisor, FM1
Cotutiu, P1
Stamatian, F1
Muresan, D1
Longworth, J1
Wu, D1
Huete-Ortega, M1
Wright, PC1
Vaidyanathan, S1
Latorre, JD1
Hernandez-Velasco, X1
Wolfenden, RE1
Vicente, JL1
Wolfenden, AD1
Menconi, A1
Bielke, LR1
Hargis, BM1
Tellez, G1
Bogomolovas, J1
Šimoliūnas, E1
Rinkūnaitė, I1
Smalinskaitė, L1
Podkopajev, A1
Bironaitė, D1
Weis, CA1
Marx, A1
Bukelskienė, V1
Gretz, N1
Grabauskienė, V1
Labeit, D1
Labeit, S1
Pradhan, S1
Regmi, T1
Ranjit, M1
Pant, B1
Luo, C1
Yu, Q1
Wang, H1
Li, HF1
Chen, WJ1
Zheng, Y1
Sakurai, H1
Kiuchi, M1
Heck, C1
Jin, T1
Zhang, L1
Jiang, K1
Jiang, M1
Yue, D1
Wan, Y1
Xing, H1
Yang, Y1
Cui, Y1
Chen, B1
Qian, G1
Lu, JB1
Jian, J1
Huang, W1
Lin, H1
Li, J1
Zhou, M1
Artola, RT1
Mihos, CG1
Santana, O1
Cook, PP1
Stang, AT1
Walker, LR1
Akula, SM1
Cook, FJ1
Sugamori, T1
Ishibashi, Y1
Shimada, T1
Takahashi, N1
Sakane, T1
Ohata, S1
Kunizawa, Y1
Inoue, S1
Nakamura, K1
Ohta, Y1
Shimizu, H1
Katoh, H1
Oyake, N1
Murakami, Y1
Hashimoto, M1
Nishi, I1
Ilda, K1
Kawano, S1
Masumi, T1
Fumikura, Y1
Ohtsuka, S1
Watanabe, S1
Yamaguchi, I1
Staudt, A1
Böhm, M1
Knebel, F1
Grosse, Y1
Bischoff, C1
Hummel, A1
Dahm, JB1
Borges, A1
Jochmann, N1
Wernecke, KD1
Wallukat, G1
Baumann, G1
Felix, SB1
Iwanaga, Y1
Gu, Y1
Dieterle, T1
Presotto, C1
Del Soldato, P1
Peterson, KL1
Ongini, E1
Condorelli, G1
Ross, J1
Fahim, MR1
Halim, SM1
Kamel, I1
Bertuglia, S1
Reiter, RJ1
Winlaw, DS1
Smythe, GA1
Keogh, AM1
Schyvens, CG1
Spratt, PM1
Macdonald, PS1
Campa, PP1
Puddu, PE1
Schiariti, M1
Monti, F1
Dawodu, AA1
Gentile, C1
Lilla Della Monica, PL1
Vaccaro, M1
De Biase, L1
Joseph, T1
Olivier, B1
Magnier, S1
Brugières, L1
Casasoprana, A1
Osterziel, KJ1
Bode-Böger, SM1
Strohm, O1
Ellmer, AE1
Bit-Avragim, N1
Hänlein, D1
Ranke, MB1
Dietz, R1
Böger, RH1
Osorio, JC1
Xu, X1
Vogel, T1
Ochoa, M1
Laycock, S1
Hintze, TH1
Popov, VG1
Sidorenko, BA1
Gruzdev, AK1
Nemirovskaia, MA1
Zharov, EI1
Vertkin, AL1
Pomerantsev, VP1
Beck, OA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicentre, Randomized, Double-blind, Prospective Investigation on the Effects of Immunoadsorption on Cardiac Function in Patients With Dilated Cardiomyopathy[NCT00558584]200 participants (Anticipated)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrates and Cardiomyopathy, Dilated

ArticleYear
    Obesity science & practice, 2016, Volume: 2, Issue:1

    Topics: Absorptiometry, Photon; Adult; Air Pollutants; Alkynes; Alleles; Animals; Anthracenes; Anthraquinone

2016

Trials

4 trials available for nitrates and Cardiomyopathy, Dilated

ArticleYear
    Obesity science & practice, 2016, Volume: 2, Issue:1

    Topics: Absorptiometry, Photon; Adult; Air Pollutants; Alkynes; Alleles; Animals; Anthracenes; Anthraquinone

2016
Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy.
    Circulation, 2002, Nov-05, Volume: 106, Issue:19

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoantibodies; Calc

2002
Role of nitric oxide in the vasodilator effect of recombinant human growth hormone in patients with dilated cardiomyopathy.
    Cardiovascular research, 2000, Jan-14, Volume: 45, Issue:2

    Topics: Cardiomyopathy, Dilated; Chi-Square Distribution; Cyclic GMP; Double-Blind Method; Female; Growth Ho

2000
[Effect of vasodilator agents on the effectiveness of the complex treatment of patients with ischemic heart disease and congestive heart failure].
    Kardiologiia, 1989, Volume: 29, Issue:4

    Topics: Aged; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Digoxin; Drug Synergism;

1989

Other Studies

14 other studies available for nitrates and Cardiomyopathy, Dilated

ArticleYear
Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure.
    Clinical science (London, England : 1979), 2020, 10-30, Volume: 134, Issue:20

    Topics: Animals; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cationic Amino Acid Transporter 1; En

2020
Dietary nitrate increases exercise tolerance in patients with non-ischemic, dilated cardiomyopathy-a double-blind, randomized, placebo-controlled, crossover trial.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2016, Volume: 35, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Cardiomyopathy, Dilated; Dietary Supplements; Exercise Test; Exercis

2016
Increased nitric oxide in proportion to the severity of heart failure in patients with dilated cardiomyopathy: close correlation of tumor necrosis factor-alpha with systemic and local production of nitric oxide.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:7

    Topics: Adult; Aged; Arm; Cardiomyopathy, Dilated; Case-Control Studies; Female; Heart Failure; Heart Functi

2002
Effects of anti-vasospastic agents in Japanese patients with dilated cardiomyopathy and coronary vasospasm.
    Japanese heart journal, 2002, Volume: 43, Issue:4

    Topics: Adult; Aged; Atrial Fibrillation; Calcium Channel Blockers; Cardiac Catheterization; Cardiomyopathy,

2002
A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiomyopathy, Dilated; Cricetinae; Cytos

2004
The role of oxidative products of nitrous oxide and the tumor necrosis factor alpha in dilated cardiomyopathy.
    The Egyptian journal of immunology, 2004, Volume: 11, Issue:1

    Topics: Analysis of Variance; Blood Pressure; Cardiomyopathy, Dilated; Diastole; Echocardiography; Female; H

2004
Melatonin reduces ventricular arrhythmias and preserves capillary perfusion during ischemia-reperfusion events in cardiomyopathic hamsters.
    Journal of pineal research, 2007, Volume: 42, Issue:1

    Topics: Angiotensin II; Animals; Antioxidants; Arrhythmias, Cardiac; Arterioles; Capillary Permeability; Car

2007
Increased nitric oxide production in heart failure.
    Lancet (London, England), 1994, Aug-06, Volume: 344, Issue:8919

    Topics: Aged; Cardiomyopathy, Dilated; Female; Heart Failure; Heart Function Tests; Humans; Male; Middle Age

1994
[Refractory heart failure: it requires the use of polychemotherapy. What is the rationale?].
    Cardiologia (Rome, Italy), 1995, Volume: 40, Issue:12 Suppl 1

    Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiomy

1995
[Cardiomyopathy induced by catecholamines in neuroblastoma].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1997, Volume: 4, Issue:1

    Topics: Adrenal Gland Neoplasms; Cardiomyopathy, Dilated; Catecholamines; Diuretics; Female; Humans; Infant;

1997
Plasma nitrate accumulation during the development of pacing-induced dilated cardiac myopathy in conscious dogs is due to renal impairment.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:1

    Topics: Animals; Ascites; Cachexia; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Consciousness; Crea

2001
[Actual problems of the treatment of acute myocardial infarction].
    Kardiologiia, 1989, Volume: 29, Issue:10

    Topics: Aged; Cardiomyopathy, Dilated; Drug Evaluation; Drug Therapy, Combination; Hemodynamics; Humans; Mid

1989
[Combined pharmacotherapy in cardiology].
    Kardiologiia, 1989, Volume: 29, Issue:2

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cardiac Glycosides; Cardiomyopathy, Dilated; Card

1989
[Significance of nitrates in acute therapy of heart failure with and without lung edema].
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 1

    Topics: Cardiac Output, Low; Cardiomyopathy, Dilated; Dobutamine; Drug Therapy, Combination; Heart Failure;

1985