nitrates has been researched along with Cardiac Hypertrophy in 18 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Population studies indicate that moderate hyperbilirubinemia is associated with reduced incidence of cardiovascular diseases, including hypertension." | 7.75 | Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice. ( Granger, JP; Stec, DE; Vera, T, 2009) |
| "The fact that both E and L delayed cardiac hypertrophy/hyperplasia and aortic growth and raised aortic endothelium NOS activity indicates a protective effect on cardiovascular damage due to aging, exerted through inhibition of angiotensin II." | 7.71 | Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging. ( Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA, 2001) |
| " Perindoprilat (1 microM), an ACE inhibitor, also restrained the progression of cardiac hypertrophy and augmented NO release." | 7.69 | Role of bradykinin-NO pathway in prevention of cardiac hypertrophy by ACE inhibitor in rat cardiomyocytes. ( Fukuzawa, A; Ikeda, T; Ishigai, Y; Mori, T; Shibano, T, 1997) |
| "Two types of vasodilators are used for treatment of acute myocardial infarction: Nitrates on the one hand with predominant venodilation and agents like Phentolamie and Nitroprusside on the other hand with venodilation as well as arteriolar vasodilation." | 4.76 | [Hemodynamic guidelines in the treatment of acute myocardial infarction by means of vasodilators]. ( Zilcher, H, 1979) |
| " The electrophilic lipid 10-nitro-oleic acid (NO2-OA) inhibited hydrolase activity and also lowered BP in an angiotensin II-induced hypertension model in wild-type (WT) but not KI mice." | 3.80 | Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. ( Charles, RL; Eaton, P; Freeman, BA; Hammock, BD; Kamynina, A; Morisseau, C; Prysyazhna, O; Rudyk, O; Yang, J, 2014) |
| "Population studies indicate that moderate hyperbilirubinemia is associated with reduced incidence of cardiovascular diseases, including hypertension." | 3.75 | Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice. ( Granger, JP; Stec, DE; Vera, T, 2009) |
| " Body weight (BW), left ventricular (LV) weight (LVW), LVW/BW ratio, LV collagen volume fraction (LVCVF), cyclic GMP, and nitrite/nitrate were measured." | 3.73 | Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats. ( Chang, HR; Chen, HI; Hsu, YH; Hu, CT; Liu, CJ, 2005) |
| "The fact that both E and L delayed cardiac hypertrophy/hyperplasia and aortic growth and raised aortic endothelium NOS activity indicates a protective effect on cardiovascular damage due to aging, exerted through inhibition of angiotensin II." | 3.71 | Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging. ( Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA, 2001) |
| " Perindoprilat (1 microM), an ACE inhibitor, also restrained the progression of cardiac hypertrophy and augmented NO release." | 3.69 | Role of bradykinin-NO pathway in prevention of cardiac hypertrophy by ACE inhibitor in rat cardiomyocytes. ( Fukuzawa, A; Ikeda, T; Ishigai, Y; Mori, T; Shibano, T, 1997) |
| "Although the etiology of congestive heart failure is complex, a disturbance of myocardial function due to ischemic heart disease or various forms of cardiomyopathy is by far the leading causative factor." | 2.37 | Congestive heart failure--pathophysiology and medical treatment. ( Remme, WJ, 1986) |
| "Reduced bioavailability of endogenous nitric oxide (NO) is a central pathophysiological event in hypertension and other cardiovascular diseases." | 1.37 | Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension. ( Carlström, M; Hezel, M; Larsson, E; Lundberg, JO; Persson, AE; Scheffer, PG; Teerlink, T; Weitzberg, E, 2011) |
| "Captopril treatment reversed the increments in pressure back to normal values by the fourth week." | 1.33 | Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat. ( Al-Shabanah, O; Khattab, MM; Mostafa, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Gee, LC | 1 |
| Massimo, G | 1 |
| Lau, C | 1 |
| Primus, C | 1 |
| Fernandes, D | 1 |
| Chen, J | 1 |
| Rathod, KS | 1 |
| Hamers, AJP | 1 |
| Filomena, F | 1 |
| Nuredini, G | 1 |
| Ibrahim, AS | 1 |
| Khambata, RS | 1 |
| Gupta, AK | 1 |
| Moon, JC | 1 |
| Kapil, V | 1 |
| Ahluwalia, A | 1 |
| Erkens, R | 1 |
| Suvorava, T | 1 |
| Sutton, TR | 1 |
| Fernandez, BO | 1 |
| Mikus-Lelinska, M | 1 |
| Barbarino, F | 1 |
| Flögel, U | 1 |
| Kelm, M | 1 |
| Feelisch, M | 1 |
| Cortese-Krott, MM | 1 |
| Charles, RL | 1 |
| Rudyk, O | 1 |
| Prysyazhna, O | 1 |
| Kamynina, A | 1 |
| Yang, J | 1 |
| Morisseau, C | 1 |
| Hammock, BD | 1 |
| Freeman, BA | 1 |
| Eaton, P | 1 |
| Vera, T | 1 |
| Granger, JP | 1 |
| Stec, DE | 1 |
| Carlström, M | 1 |
| Persson, AE | 1 |
| Larsson, E | 1 |
| Hezel, M | 1 |
| Scheffer, PG | 1 |
| Teerlink, T | 1 |
| Weitzberg, E | 1 |
| Lundberg, JO | 1 |
| Kase, H | 1 |
| Hashikabe, Y | 1 |
| Uchida, K | 1 |
| Nakanishi, N | 1 |
| Hattori, Y | 1 |
| Hu, CT | 1 |
| Chang, HR | 1 |
| Hsu, YH | 1 |
| Liu, CJ | 1 |
| Chen, HI | 1 |
| Khattab, MM | 1 |
| Mostafa, A | 1 |
| Al-Shabanah, O | 1 |
| Li, HJ | 1 |
| Yin, H | 2 |
| Yao, YY | 2 |
| Shen, B | 2 |
| Bader, M | 1 |
| Chao, L | 3 |
| Chao, J | 3 |
| Gorlin, R | 1 |
| Ishigai, Y | 1 |
| Mori, T | 1 |
| Ikeda, T | 1 |
| Fukuzawa, A | 1 |
| Shibano, T | 1 |
| Wolf, WC | 1 |
| Yoshida, H | 1 |
| Agata, J | 1 |
| González Bosc, LV | 1 |
| Kurnjek, ML | 1 |
| Müller, A | 1 |
| Terragno, NA | 1 |
| Basso, N | 1 |
| Plotnick, GD | 1 |
| Greene, HL | 1 |
| Carliner, NH | 1 |
| Becker, LC | 1 |
| Fisher, ML | 1 |
| Lloyd, EA | 1 |
| Zilcher, H | 1 |
| Remme, WJ | 1 |
4 reviews available for nitrates and Cardiac Hypertrophy
| Article | Year |
|---|---|
Prevention of remodeling of the heart after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Clinical Trials | 1995 |
The use of vasodilator agents in the treatment of heart failure.
Topics: Cardiac Output; Cardiomegaly; Catheterization; Chronic Disease; Coronary Vessels; Dose-Response Rela | 1979 |
[Hemodynamic guidelines in the treatment of acute myocardial infarction by means of vasodilators].
Topics: Arrhythmias, Cardiac; Cardiac Output; Cardiomegaly; Death, Sudden; Diuretics; Heart Block; Heart Ven | 1979 |
Congestive heart failure--pathophysiology and medical treatment.
Topics: Autonomic Nervous System; Blood Pressure; Calcium; Cardiomegaly; Cardiotonic Agents; Digitalis; Diur | 1986 |
14 other studies available for nitrates and Cardiac Hypertrophy
| Article | Year |
|---|---|
Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide.
Topics: Animals; Cardiomegaly; Case-Control Studies; Clinical Studies as Topic; Disease Models, Animal; Fibr | 2022 |
Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection.
Topics: Animals; Aorta; Cardiomegaly; Glutathione; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Repe | 2018 |
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cellulase; Diet, Mediterranean; Disease Model | 2014 |
Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice.
Topics: Angiotensin II; Animals; Bilirubin; Blood Pressure; Cardiomegaly; Disease Models, Animal; Glucuronos | 2009 |
Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension.
Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Renal; Kidney | 2011 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Dis | 2005 |
Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats.
Topics: Algorithms; Animals; Arteries; Body Weight; Cardiomegaly; Cell Count; Collagen; Cyclic GMP; Electroc | 2005 |
Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartate Aminotransferases; Blood Pressure; Body | 2005 |
Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.
Topics: Adenoviridae; Animals; Blotting, Western; Cardiomegaly; Electrophoretic Mobility Shift Assay; Enzyme | 2007 |
Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction.
Topics: Animals; Capillaries; Cardiac Output, Low; Cardiomegaly; Cells, Cultured; Collagen; Coronary Vessels | 2007 |
Role of bradykinin-NO pathway in prevention of cardiac hypertrophy by ACE inhibitor in rat cardiomyocytes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Bradykinin; Bradykinin Receptor | 1997 |
Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure.
Topics: Adenoviridae; Animals; Blood Pressure; Blood Urea Nitrogen; Cardiomegaly; Cyclic GMP; Fibrosis; Gene | 2000 |
Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; A | 2001 |
Clinical indicators of left main coronary artery disease in unstable angina.
Topics: Angina Pectoris; Angiography; Anticoagulants; Calcinosis; Cardiac Catheterization; Cardiomegaly; Col | 1979 |