Page last updated: 2024-10-19

nitrates and Cancer of Colon

nitrates has been researched along with Cancer of Colon in 53 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"Antitumour agents such as flavone acetic acid, xanthenone acetic acid (XAA), 5,6-dimethylxanthenone-4-acetic acid and tumour necrosis factor-alpha, following single dose administration to mice with colon 38 adenocarcinomas, induce tumour haemorrhagic necrosis and an elevation in plasma nitrate."7.68Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis. ( Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E, 1993)
"Vinblastine or colchicine, administered intraperitoneally to B6D2F1 mice with advanced subcutaneous colon 38 tumours, induced substantial tumour growth delays with progressive development of haemorrhagic necrosis beginning within 8 hours of treatment."7.68Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism. ( Baguley, BC; Holdaway, KM; Thomsen, LL; Zhuang, L; Zwi, LJ, 1991)
" ONOO(-)scavengers ebselen and uric acid significantly suppressed the EPR effect in mouse sarcoma 180 (S-180) tumors."3.71Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases. ( Akaike, T; Hayashida, K; Maeda, H; Okamoto, T; Okuyama, A; Wu, J, 2001)
"Antitumour agents such as flavone acetic acid, xanthenone acetic acid (XAA), 5,6-dimethylxanthenone-4-acetic acid and tumour necrosis factor-alpha, following single dose administration to mice with colon 38 adenocarcinomas, induce tumour haemorrhagic necrosis and an elevation in plasma nitrate."3.68Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis. ( Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E, 1993)
"Vinblastine or colchicine, administered intraperitoneally to B6D2F1 mice with advanced subcutaneous colon 38 tumours, induced substantial tumour growth delays with progressive development of haemorrhagic necrosis beginning within 8 hours of treatment."3.68Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism. ( Baguley, BC; Holdaway, KM; Thomsen, LL; Zhuang, L; Zwi, LJ, 1991)
"The increase in colorectal cancer risk with increasing nitrate concentration is lower than in some recent studies, and applies only over a small range."2.82Nitrates in drinking water and cancers of the colon and rectum: a meta-analysis of epidemiological studies. ( Elwood, JM; Werf, BV, 2022)
" However, their long-term use is associated with adverse gastrointestinal effects."1.38NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model. ( Chattopadhyay, M; Kashfi, K; Kodela, R; Olson, KR, 2012)
"Epidemiological studies suggest colon cancer to be possibly associated with nitrate in drinking water."1.36Estimation of incidence and social cost of colon cancer due to nitrate in drinking water in the EU: a tentative cost-benefit assessment. ( de Kok, TM; Rabl, A; van Grinsven, HJ, 2010)
"The adjusted odds ratios for colon cancer death for those with high NO3-N levels in their drinking water, as compared to the lowest tertile, were 0."1.34Nitrate in drinking water and risk of death from colon cancer in Taiwan. ( Chang, CC; Wu, DC; Yang, CY, 2007)
"The adhesion of colon cancer cells (colo201) and neutrophils to endothelial cells which had been briefly exposed to either hypoxanthine/xanthine oxidase, or hydrogen peroxide, or peroxynitrite was analyzed in the absence of de novo protein synthesis."1.30Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals. ( Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N, 1999)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19907 (13.21)18.7374
1990's20 (37.74)18.2507
2000's13 (24.53)29.6817
2010's12 (22.64)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Elwood, JM1
Werf, BV1
Miller, PE1
Lazarus, P1
Lesko, SM1
Cross, AJ1
Sinha, R1
Laio, J1
Zhu, J1
Harper, G1
Muscat, JE1
Hartman, TJ1
Kuyumcu, A1
Akyol, A1
Buyuktuncer, Z1
Ozmen, MM1
Besler, HT1
Iskandar, MZ1
Quasem, W1
El-Omar, M1
Erdman, SE1
Rao, VP1
Poutahidis, T1
Rogers, AB1
Taylor, CL1
Jackson, EA1
Ge, Z1
Lee, CW1
Schauer, DB1
Wogan, GN1
Tannenbaum, SR1
Fox, JG1
Chiu, HF2
Tsai, SS2
Wu, TN2
Yang, CY3
Chattopadhyay, M2
Goswami, S1
Rodes, DB1
Kodela, R2
Velazquez, CA1
Boring, D1
Crowell, JA1
Kashfi, K3
Bocca, C2
Bozzo, F2
Bassignana, A1
Miglietta, A2
van Grinsven, HJ1
Rabl, A1
de Kok, TM1
Pathi, SS1
Jutooru, I1
Chadalapaka, G1
Sreevalsan, S1
Anand, S1
Thatcher, GR2
Safe, S1
Kawaratani, Y1
Harada, T1
Hirata, Y1
Nagaoka, Y1
Tanimura, S1
Shibano, M1
Taniguchi, M1
Yasuda, M1
Baba, K1
Uesato, S1
Chen, PS1
Ievolella, M1
Olson, KR1
Mirvish, SS1
Haorah, J1
Zhou, L1
Clapper, ML1
Harrison, KL1
Povey, AC1
Akbulut, H1
Altuntas, F1
Akbulut, KG1
Ozturk, G1
Cindoruk, M1
Unal, E1
Icli, F1
Steenland, K1
Moe, C1
De Roos, AJ1
Ward, MH1
Lynch, CF1
Cantor, KP1
Borgo, S1
Williams, JL1
Chen, J1
Gao, J1
Glekas, A1
Benedini, F1
Del Soldato, P1
Rigas, B1
Riganti, C1
Miraglia, E1
Viarisio, D1
Costamagna, C1
Pescarmona, G1
Ghigo, D1
Bosia, A1
Knöbel, Y1
Weise, A1
Glei, M1
Sendt, W1
Claussen, U1
Pool-Zobel, BL1
Dinc, S1
Ozbirecikli, B1
Kuru, B1
Gulcelik, MA1
Ustun, H1
Alagol, H1
Oz, M1
Wu, DC1
Chang, CC1
Hagos, GK1
Carroll, RE1
Kouznetsova, T1
Li, Q1
Toader, V1
Fernandez, PA1
Swanson, SM1
Weisburger, JH3
Horn, CL1
Barnes, WS1
Horn, C1
Nauss, KM1
Newberne, PM1
Venitt, S1
Morales-Suárez-Varela, MM1
Llopis-Gonzalez, A1
Tejerizo-Perez, ML1
Fine, DM1
Lo, CF1
Aguillar, L1
Blackmon, DL1
Montrose, MH1
Ferrándiz, J1
López, A1
Llopis, A1
Morales, M1
Tejerizo, ML1
Baguley, BC6
Cole, G1
Thomsen, LL7
Li, Z2
Veszelovszky, E1
Fukumura, D1
Yuan, F1
Endo, M1
Jain, RK1
Scott, JM1
Topley, P1
Knowles, RG1
Keerie, AJ1
Frend, AJ1
Unno, N1
Menconi, MJ1
Fink, MP1
Sandoval, M1
Ronzio, RA1
Muanza, DN1
Clark, DA1
Miller, MJ1
Witthöft, T1
Eckmann, L1
Kim, JM1
Kagnoff, MF1
Suzuki, K1
Eguchi, H1
Koh, YH1
Park, YS1
Taniguchi, N1
Washo-Stultz, D1
Hoglen, N1
Bernstein, H1
Bernstein, C1
Payne, CM1
Haklar, G1
Sayin-Ozveri, E1
Yüksel, M1
Aktan, AO1
Yalçin, AS1
Wu, J1
Akaike, T1
Hayashida, K1
Okamoto, T1
Okuyama, A1
Maeda, H1
Wynder, EL1
Reddy, BS1
McCoy, GD1
Williams, GM1
Hill, MJ1
Zaldivar, R1
Kälble, T3
Tricker, AR3
Berger, M1
Amelung, F1
Waldherr, R2
Hothorn, L1
Möhring, K3
Staehler, G3
Holdaway, KM1
Zhuang, L3
Zwi, LJ1
Rewcastle, GW1
Atwell, GJ1
Boyd, M1
Denny, WA1
Ching, LM2
Gavin, JB1
Lauer, K1
Friedl, P1
Hoang, J1
Berger, MR1
Geiss, H1

Reviews

8 reviews available for nitrates and Cancer of Colon

ArticleYear
Nitrates in drinking water and cancers of the colon and rectum: a meta-analysis of epidemiological studies.
    Cancer epidemiology, 2022, Volume: 78

    Topics: Case-Control Studies; Colonic Neoplasms; Drinking Water; Humans; Nitrates; Rectal Neoplasms

2022
Total N-nitroso compounds and their precursors in hot dogs and in the gastrointestinal tract and feces of rats and mice: possible etiologic agents for colon cancer.
    The Journal of nutrition, 2002, Volume: 132, Issue:11 Suppl

    Topics: Animals; Cattle; Child; Colitis; Colonic Neoplasms; Deoxyguanosine; Diabetes Mellitus, Type 2; Diges

2002
Possible genotoxic carcinogens in foods in relation to cancer causation.
    Seminars in oncology, 1983, Volume: 10, Issue:3

    Topics: Animals; Breast Neoplasms; Carbolines; Carcinogens, Environmental; Cattle; Colonic Neoplasms; Cookin

1983
Nutritional modulation of cancer.
    Cancer detection and prevention, 1980, Volume: 3, Issue:2

    Topics: Animals; Carcinogens; Colonic Neoplasms; Diet; Esophageal Neoplasms; Female; Humans; Liver Neoplasms

1980
Mutagens in human faeces. Are they relevant to cancer of the large bowel?
    Mutation research, 1982, Volume: 98, Issue:3

    Topics: Colonic Neoplasms; Diet, Vegetarian; Feces; Female; Humans; Male; Mutagens; Nitrates; Nitrites; Nitr

1982
Diet and cancer of the gastrointestinal tract.
    Advances in internal medicine, 1977, Volume: 22

    Topics: Alcoholism; Colonic Neoplasms; Diet; Diet Therapy; Dietary Carbohydrates; Dietary Fats; Esophageal N

1977
Role of bacteria in human carcinogenesis.
    Journal of human nutrition, 1979, Volume: 33, Issue:6

    Topics: Amino Acids; Bacteria; Bile Acids and Salts; Biliary Tract Neoplasms; Carcinogens; Colonic Neoplasms

1979
The history of nitrite in human nutrition: a contribution from German cookery books.
    Journal of clinical epidemiology, 1991, Volume: 44, Issue:3

    Topics: Colonic Neoplasms; Cooking; Food Additives; Germany; History, 16th Century; History, 17th Century; H

1991

Trials

1 trial available for nitrates and Cancer of Colon

ArticleYear
Improved oxidative status in major abdominal surgery patients after N-acetyl cystein supplementation.
    Nutrition journal, 2015, Jan-06, Volume: 14

    Topics: Abdomen; Acetylcysteine; Aged; Antioxidants; Colonic Neoplasms; Female; Glutathione; Humans; Male; M

2015

Other Studies

44 other studies available for nitrates and Cancer of Colon

ArticleYear
Meat-related compounds and colorectal cancer risk by anatomical subsite.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cookin

2013
5-Fluorouracil cardiotoxicity: reversible left ventricular systolic dysfunction with early detection.
    BMJ case reports, 2015, May-02, Volume: 2015

    Topics: Adult; Antimetabolites, Antineoplastic; Calcium Channel Blockers; Cardiotoxicity; Colonic Neoplasms;

2015
Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Jan-27, Volume: 106, Issue:4

    Topics: Animals; Arginine; Colon; Colonic Neoplasms; DNA-Binding Proteins; Enzyme Inhibitors; Helicobacter h

2009
Colon cancer and content of nitrates and magnesium in drinking water.
    Magnesium research, 2010, Volume: 23, Issue:2

    Topics: Aged; Cities; Colonic Neoplasms; Confidence Intervals; Female; Humans; Magnesium; Male; Middle Aged;

2010
NO-releasing NSAIDs suppress NF-κB signaling in vitro and in vivo through S-nitrosylation.
    Cancer letters, 2010, Dec-08, Volume: 298, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Caspase 3; Cell Prolif

2010
Antiproliferative effect of a novel nitro-oxy derivative of celecoxib in human colon cancer cells: role of COX-2 and nitric oxide.
    Anticancer research, 2010, Volume: 30, Issue:7

    Topics: Apoptosis; Benzyl Compounds; beta Catenin; Celecoxib; Cell Growth Processes; Cell Membrane; Cell Nuc

2010
Estimation of incidence and social cost of colon cancer due to nitrate in drinking water in the EU: a tentative cost-benefit assessment.
    Environmental health : a global access science source, 2010, Oct-06, Volume: 9

    Topics: Colonic Neoplasms; Cost of Illness; Cost-Benefit Analysis; Diet; Europe; European Union; Fertilizers

2010
GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway.
    Molecular cancer research : MCR, 2011, Volume: 9, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Ne

2011
New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl group.
    Bioorganic & medicinal chemistry, 2011, Jul-01, Volume: 19, Issue:13

    Topics: Acetates; Animals; Aspirin; Benzoates; Carbamates; Cell Division; Cell Line, Tumor; Colonic Neoplasm

2011
Does calcium in drinking water modify the association between nitrate in drinking water and risk of death from colon cancer?
    Journal of water and health, 2011, Volume: 9, Issue:3

    Topics: Aged; Calcium; Case-Control Studies; Colonic Neoplasms; Drinking Water; Effect Modifier, Epidemiolog

2011
A novel nitro-oxy substituted analogue of rofecoxib reduces human colon cancer cell growth.
    Molecular and cellular biochemistry, 2012, Volume: 361, Issue:1-2

    Topics: 4-Butyrolactone; Antineoplastic Agents; beta Catenin; Cadherins; Cell Line, Tumor; Cell Proliferatio

2012
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse model.
    Biochemical and biophysical research communications, 2012, Mar-16, Volume: 419, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Proliferation; Colonic Neoplasm

2012
Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma.
    Cytokine, 2002, Nov-24, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

2002
Epidemiology and drinking water: are we running dry?
    Epidemiology (Cambridge, Mass.), 2003, Volume: 14, Issue:6

    Topics: Colonic Neoplasms; Humans; Nitrates; Rectal Neoplasms; United States; Water Supply

2003
Nitrate in public water supplies and the risk of colon and rectum cancers.
    Epidemiology (Cambridge, Mass.), 2003, Volume: 14, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Nitrates; Rect

2003
Positional isomerism markedly affects the growth inhibition of colon cancer cells by nitric oxide-donating aspirin in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Apoptosis; Aspirin; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Growth

2005
Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux.
    Cancer research, 2005, Jan-15, Volume: 65, Issue:2

    Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; Cyclic GMP; Doxorubicin; Drug Resistance, Multiple;

2005
Ferric iron is genotoxic in non-transformed and preneoplastic human colon cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:5

    Topics: Adenoma; Cell Line, Tumor; Chromosome Aberrations; Colon; Colonic Neoplasms; Comet Assay; DNA Damage

2007
Long term administration of granulocyte-macrophage colony stimulating factor decreases development of 1-2 dimethylhydrazine-induced colon cancer in rats.
    Journal of surgical oncology, 2007, Jan-01, Volume: 95, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Free Radica

2007
Nitrate in drinking water and risk of death from colon cancer in Taiwan.
    Environment international, 2007, Volume: 33, Issue:5

    Topics: Case-Control Studies; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Nitrates; Risk Factors;

2007
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:8

    Topics: Animals; Apoptosis; Azoxymethane; Cell Count; Cell Line, Tumor; Cell Proliferation; Chemoprevention;

2007
Nutrition and cancer: mechanisms of genotoxic and epigenetic carcinogens in nutritional carcinogenesis.
    Bulletin of the New York Academy of Medicine, 1982, Volume: 58, Issue:3

    Topics: Animals; Colonic Neoplasms; Dietary Fats; Female; Humans; Male; Mutation; Neoplasms; Nitrates; Nitri

1982
Impact of nitrates in drinking water on cancer mortality in Valencia, Spain.
    European journal of epidemiology, 1995, Volume: 11, Issue:1

    Topics: Aged; Colonic Neoplasms; Cross-Sectional Studies; Drinking; Female; Humans; Male; Middle Aged; Nitra

1995
Cellular chloride depletion inhibits cAMP-activated electrogenic chloride fluxes in HT29-18-C1 cells.
    The Journal of membrane biology, 1995, Volume: 145, Issue:2

    Topics: Anions; Biological Transport; Bumetanide; Carrier Proteins; Cations; Cell Membrane Permeability; Cel

1995
Spatial interaction between neighbouring counties: cancer mortality data in Valencia Spain.
    Biometrics, 1995, Volume: 51, Issue:2

    Topics: Colonic Neoplasms; Demography; Fertilizers; Humans; Male; Models, Statistical; Neoplasms; Nitrates;

1995
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C5

1993
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids;

1993
Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions.
    The American journal of pathology, 1997, Volume: 150, Issue:2

    Topics: Adenocarcinoma; Animals; Capillary Permeability; Colonic Neoplasms; Endothelium, Vascular; Female; H

1997
Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.
    Cancer research, 1997, Aug-01, Volume: 57, Issue:15

    Topics: Adenocarcinoma; Amidines; Animals; Arginine; Benzylamines; Colonic Neoplasms; Enzyme Inhibitors; Hem

1997
Nitric oxide-induced hyperpermeability of human intestinal epithelial monolayers is augmented by inhibition of the amiloride-sensitive Na(+)-H+ antiport: potential role of peroxynitrous acid.
    Surgery, 1997, Volume: 122, Issue:2

    Topics: Amiloride; Cell Membrane Permeability; Colonic Neoplasms; Deferoxamine; Humans; Intestinal Mucosa; M

1997
Peroxynitrite-induced apoptosis in epithelial (T84) and macrophage (RAW 264.7) cell lines: effect of legume-derived polyphenols (phytolens).
    Nitric oxide : biology and chemistry, 1997, Volume: 1, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Bepridil; Biphenyl Compounds; Cell Division; Cell Line; Cell Survi

1997
Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Adenocarcinoma; Cell Line; Colon; Colonic Neoplasms; Escherichia coli; Gene Expression Regulation, E

1998
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
    Biochemical and biophysical research communications, 1999, Apr-02, Volume: 257, Issue:1

    Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinom

1999
Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesis.
    Nutrition and cancer, 1999, Volume: 35, Issue:2

    Topics: Apoptosis; Bile Acids and Salts; Colonic Neoplasms; Deoxycholic Acid; Enzyme Inhibitors; Fluorescent

1999
Different kinds of reactive oxygen and nitrogen species were detected in colon and breast tumors.
    Cancer letters, 2001, Apr-26, Volume: 165, Issue:2

    Topics: Acridines; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Hypochlorous Acid; Lumi

2001
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:4

    Topics: Adenocarcinoma; Animals; Azoles; Bradykinin; Capillary Permeability; Collagenases; Colonic Neoplasms

2001
Epidemiology of gastric and colo-rectal cancer in the United States and Chile with particular reference to the role of dietary and nutritional variables, nitrate fertilizer pollution, and N-nitroso compounds.
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, praventive Medizin, 1977, Volume: 164, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Carcinogens; Child; Child, Preschool; Chile; Colonic Neoplasms

1977
Tumor induction in a rat model for ureterosigmoidostomy without evidence of nitrosamine formation.
    The Journal of urology, 1991, Volume: 146, Issue:3

    Topics: Adenocarcinoma; Adenoma; Amines; Anastomosis, Surgical; Animals; Colon, Sigmoid; Colonic Neoplasms;

1991
Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Animals; Colchicine; Colonic Neoplasms; Drug Resistance; Leukemia, Experimental; Mic

1991
Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:9

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Macrophages; Me

1991
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Methylatio

1991
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Animals; Antineoplastic Agents; Arginine; Cell Survival; Colonic Neoplasms; Dexamethasone; Flavonoid

1990
Ureterosigmoidostomy: long-term results, risk of carcinoma and etiological factors for carcinogenesis.
    The Journal of urology, 1990, Volume: 144, Issue:5

    Topics: Adult; Colon, Sigmoid; Colonic Neoplasms; Follow-Up Studies; Humans; Nitrates; Nitrites; Nitrosamine

1990
The role of nitrate, nitrite and N-nitrosamines in carcinogenesis of colon tumours following ureterosigmoidostomy.
    Urological research, 1990, Volume: 18, Issue:2

    Topics: Animals; Bacteria; Colon; Colonic Neoplasms; Feces; Humans; Nitrates; Nitrites; Nitrosamines; Rats;

1990