Page last updated: 2024-10-19

nitrates and Bronchial Hyperreactivity

nitrates has been researched along with Bronchial Hyperreactivity in 9 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
"Eleven steroid-naive adults with mild-to-moderate persistent asthma were treated with mometasone furoate dry powder inhaler, 400 microg/d, for 8 weeks, followed by a 4-week washout."5.14Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma. ( Berro, A; Casale, TB; Mehta, V; Romero, FA; Stokes, JR, 2009)
"Pretreatment with phosphoramidon, an NEP inhibitor, also enhanced SP- and ET-1-induced bronchoconstriction."1.30Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase. ( Hirata, K; Kanazawa, H; Yoshikawa, J, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, S1
Basavan, D1
Muthureddy Nataraj, SK1
Raju, KR1
Babu, UV1
L M, SK1
Gupta, R1
Mehta, V1
Stokes, JR1
Berro, A1
Romero, FA1
Casale, TB1
Nevin, BJ1
Broadley, KJ1
Komlósi, ZI1
Pozsonyi, E1
Tábi, T1
Szöko, E1
Nagy, A1
Bartos, B1
Kozma, GT1
Tamási, L1
Orosz, M1
Magyar, P1
Losonczy, G1
Sadeghi-Hashjin, G2
Folkerts, G2
Henricks, PA2
Verheyen, AK1
van der Linde, HJ1
van Ark, I1
Coene, A1
Nijkamp, FP2
Muijsers, RB1
Kanazawa, H1
Hirata, K1
Yoshikawa, J1
Gabazza, EC1
Taguchi, O1
Tamaki, S1
Murashima, S1
Kobayashi, H1
Yasui, H1
Kobayashi, T1
Hataji, O1
Adachi, Y1
Strohmeier, GR1
Walsh, JH1
Klings, ES1
Farber, HW1
Cruikshank, WW1
Center, DM1
Fenton, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Mometasone on Markers of Airway Inflammation[NCT00711165]Phase 412 participants (Actual)Interventional2005-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrates and Bronchial Hyperreactivity

ArticleYear
Peroxynitrite in airway diseases.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28, Issue:12

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Humans; Lung; Lung Diseases; Macrophages, Alveolar; Nitr

1998

Trials

1 trial available for nitrates and Bronchial Hyperreactivity

ArticleYear
Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:1

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Allergic Agents; Anti-Inflammatory

2009

Other Studies

7 other studies available for nitrates and Bronchial Hyperreactivity

ArticleYear
Assessment of inhibitory potential of Pothos scandens L. on ovalbumin-induced airway hyperresponsiveness in balb/c mice.
    International immunopharmacology, 2014, Volume: 18, Issue:1

    Topics: Allergens; Animals; Araceae; Bronchial Hyperreactivity; Cells, Cultured; Cytokines; Down-Regulation;

2014
Comparative effects of inhaled budesonide and the NO-donating budesonide derivative, NCX 1020, against leukocyte influx and airway hyperreactivity following lipopolysaccharide challenge.
    Pulmonary pharmacology & therapeutics, 2004, Volume: 17, Issue:4

    Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronch

2004
Lipopolysaccharide exposure makes allergic airway inflammation and hyper-responsiveness less responsive to dexamethasone and inhibition of iNOS.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:7

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Dexamethasone; Drug Resistance; Female; Gluco

2006
Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:5

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Bronch

1996
Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase.
    International archives of allergy and immunology, 1999, Volume: 120, Issue:4

    Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Endothelin-1; Enzyme Activation; Glycopepti

1999
Role of nitric oxide in airway remodelling.
    Clinical science (London, England : 1979), 2000, Volume: 98, Issue:3

    Topics: Asthma; Biomarkers; Bronchi; Bronchial Hyperreactivity; Case-Control Studies; Chronic Disease; Femal

2000
Lipopolysaccharide binding protein potentiates airway reactivity in a murine model of allergic asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Feb-01, Volume: 166, Issue:3

    Topics: Acute-Phase Proteins; Adjuvants, Immunologic; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperr

2001