nitrates has been researched along with Brain Swelling in 17 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cognitive impairment and cerebral edema were observed in MHE rats and rats injected with 10 μg DA." | 5.40 | Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration. ( Chen, B; Ding, S; Hu, J; Liu, L; Wang, X; Yang, J; Ye, Y; Zhuge, Q, 2014) |
| "Uric acid is a natural antioxidant that protects the brain in a model of transient focal ischemia in rats." | 5.34 | Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. ( Amaro, S; Chamorro, A; Planas, AM; Romanos, E, 2007) |
| "Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion." | 1.46 | Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke. ( Darabi, S; Mohammadi, MT, 2017) |
| "Brain edema was determined by means of the wet-dry weight method and assessed with light microscopy on H&E-stained preparations of tissues obtained 6 and 24 hours after glyceryl trinitrate treatment." | 1.42 | Effects of nitric oxide on blood-brain barrier permeability in common carp (Cyprinus carpio L.). ( Gjurcevic, E; Ivkic, G; Klaric, MŠ; Kovacić, S; Rumora, L, 2015) |
| "Cognitive impairment and cerebral edema were observed in MHE rats and rats injected with 10 μg DA." | 1.40 | Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration. ( Chen, B; Ding, S; Hu, J; Liu, L; Wang, X; Yang, J; Ye, Y; Zhuge, Q, 2014) |
| "Uric acid is a natural antioxidant that protects the brain in a model of transient focal ischemia in rats." | 1.34 | Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. ( Amaro, S; Chamorro, A; Planas, AM; Romanos, E, 2007) |
| "We concluded that curcumin ameliorates cerebral ischemia/reperfusion injury by preventing ONOO(-) mediated blood-brain barrier damage." | 1.34 | Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. ( Hu, M; Jiang, J; Li, F; Sun, YJ; Wang, W; Zhu, DY, 2007) |
| "LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier." | 1.34 | Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007) |
| "Melatonin treatment increased survival and reduced hyperactivity linked to neurodegeneration induced by cerebral ischemia and reperfusion." | 1.31 | Protective effects of melatonin in ischemic brain injury. ( Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 12 (70.59) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Darabi, S | 1 |
| Mohammadi, MT | 1 |
| Jiang, YS | 1 |
| Wang, FR | 1 |
| Ding, S | 1 |
| Yang, J | 1 |
| Liu, L | 1 |
| Ye, Y | 1 |
| Wang, X | 1 |
| Hu, J | 1 |
| Chen, B | 1 |
| Zhuge, Q | 1 |
| Kovacić, S | 1 |
| Rumora, L | 1 |
| Gjurcevic, E | 1 |
| Klaric, MŠ | 1 |
| Ivkic, G | 1 |
| Dohare, P | 1 |
| Garg, P | 1 |
| Jain, V | 1 |
| Nath, C | 1 |
| Ray, M | 1 |
| Temiz, C | 1 |
| Tun, K | 1 |
| Ugur, HC | 1 |
| Dempsey, RJ | 1 |
| Egemen, N | 1 |
| Schliess, F | 2 |
| Foster, N | 1 |
| Görg, B | 1 |
| Reinehr, R | 1 |
| Häussinger, D | 2 |
| Romanos, E | 1 |
| Planas, AM | 1 |
| Amaro, S | 1 |
| Chamorro, A | 1 |
| Yatsushige, H | 1 |
| Calvert, JW | 1 |
| Cahill, J | 1 |
| Zhang, JH | 1 |
| Jiang, J | 1 |
| Wang, W | 1 |
| Sun, YJ | 1 |
| Hu, M | 1 |
| Li, F | 1 |
| Zhu, DY | 1 |
| Wright, G | 1 |
| Davies, NA | 1 |
| Shawcross, DL | 1 |
| Hodges, SJ | 1 |
| Zwingmann, C | 1 |
| Brooks, HF | 1 |
| Mani, AR | 1 |
| Harry, D | 1 |
| Stadlbauer, V | 1 |
| Zou, Z | 2 |
| Williams, R | 1 |
| Davies, C | 1 |
| Moore, KP | 1 |
| Jalan, R | 1 |
| Master, S | 1 |
| Gottstein, J | 1 |
| Blei, AT | 1 |
| Calapai, G | 2 |
| Marciano, MC | 2 |
| Corica, F | 1 |
| Allegra, A | 1 |
| Parisi, A | 2 |
| Frisina, N | 1 |
| Caputi, AP | 4 |
| Buemi, M | 1 |
| Cuzzocrea, S | 2 |
| McDonald, MC | 1 |
| Mazzon, E | 2 |
| Siriwardena, D | 1 |
| Costantino, G | 2 |
| Fulia, F | 2 |
| Cucinotta, G | 1 |
| Gitto, E | 2 |
| Cordaro, S | 2 |
| Barberi, I | 2 |
| De Sarro, A | 2 |
| Thiemermann, C | 1 |
| Serraino, I | 1 |
| Crupi, A | 1 |
| Firenzuoli, F | 1 |
| Squadrito, F | 1 |
| Inferrera, G | 1 |
| Rizzo, A | 1 |
| Crisafulli, C | 1 |
| Fiore, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double Blind Study Assessing the Clinical Efficacy of Combined Treatment With Uric Acid and rtPA Administered Intravenously in Acute Ischemic Stroke Patients Within the First 4.5 Hours of Symptoms Onset[NCT00860366] | Phase 2/Phase 3 | 421 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| Shuxuening Injection for the Prevention of Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage -- A Randomized, Double-blind, Placebo-parallel Controlled Clinical Trial[NCT06138353] | Phase 2/Phase 3 | 50 participants (Anticipated) | Interventional | 2023-11-13 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitrates and Brain Swelling
| Article | Year |
|---|---|
Astrocyte swelling and protein tyrosine nitration in hepatic encephalopathy.
Topics: Animals; Astrocytes; Brain Edema; Cell Size; Hepatic Encephalopathy; Humans; Nerve Tissue Proteins; | 2005 |
16 other studies available for nitrates and Brain Swelling
| Article | Year |
|---|---|
Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke.
Topics: Animals; Aquaporin 1; Brain Edema; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Di | 2017 |
Caloric restriction reduces edema and prolongs survival in a mouse glioma model.
Topics: 3-Hydroxybutyric Acid; Animals; Brain Edema; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor; | 2013 |
Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Edema; Cells, Cultured; Cognition; Dopamine; Enzyme Inh | 2014 |
Effects of nitric oxide on blood-brain barrier permeability in common carp (Cyprinus carpio L.).
Topics: Animals; Blood-Brain Barrier; Brain Edema; Carps; Nitrates; Nitric Oxide; Nitrites; Nitroglycerin; P | 2015 |
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea | 2008 |
L-arginine in focal cerebral ischemia.
Topics: Animals; Arginine; Brain Edema; Brain Ischemia; Neuroprotective Agents; Nitrates; Nitric Oxide; Nitr | 2003 |
Hypoosmotic swelling increases protein tyrosine nitration in cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Edema; Calcium Signaling; Calmodulin; Cell Size; Cells, | 2004 |
Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke.
Topics: Animals; Brain Damage, Chronic; Brain Edema; Humans; Infarction, Middle Cerebral Artery; Male; Neuro | 2007 |
Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Male; Nitrates | 2006 |
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Capillaries; Curcuma; Curcumi | 2007 |
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C | 2007 |
Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis.
Topics: Ammonia; Animals; Brain; Brain Edema; Cerebrovascular Circulation; Cranial Sinuses; Hemodynamics; In | 1999 |
Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation.
Topics: Aldehydes; Animals; Brain; Brain Edema; Brain Ischemia; Erythropoietin; Gerbillinae; Humans; Injecti | 2000 |
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Edema; Cerebral Arteries; Cyclic N-Oxides; Free R | 2000 |
Protective effects of melatonin in ischemic brain injury.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scaveng | 2000 |
Neuroprotective effects of Ginkgo biloba extract in brain ischemia are mediated by inhibition of nitric oxide synthesis.
Topics: Administration, Oral; Animals; Brain; Brain Edema; Cell Death; Dose-Response Relationship, Drug; Ger | 2000 |