nitrates has been researched along with Brain Injuries in 23 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, MN-08 also alleviated cerebral vasospasm in a cisterna magna single-injection model in rabbits." | 1.51 | The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models. ( Guo, B; Han, Y; Ju, J; Li, N; Li, S; Liu, Z; Luo, F; Mak, S; Sun, Y; Wang, Y; Wu, L; Yang, X; Zhang, G; Zhang, Z; Zhou, Q; Zhu, Z, 2019) |
| "Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion." | 1.46 | Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke. ( Darabi, S; Mohammadi, MT, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 12 (52.17) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Darabi, S | 1 |
| Mohammadi, MT | 1 |
| Luo, F | 1 |
| Wu, L | 1 |
| Zhang, Z | 2 |
| Zhu, Z | 1 |
| Liu, Z | 1 |
| Guo, B | 1 |
| Li, N | 1 |
| Ju, J | 1 |
| Zhou, Q | 1 |
| Li, S | 1 |
| Yang, X | 1 |
| Mak, S | 1 |
| Han, Y | 1 |
| Sun, Y | 1 |
| Wang, Y | 1 |
| Zhang, G | 1 |
| Thampatty, BP | 1 |
| Klamerus, MM | 1 |
| Oberly, PJ | 1 |
| Feldman, KL | 1 |
| Bell, MJ | 1 |
| Tyler-Kabara, EC | 1 |
| Adelson, PD | 1 |
| Clark, RS | 2 |
| Kochanek, PM | 2 |
| Poloyac, SM | 1 |
| Yen, HC | 1 |
| Chen, TW | 1 |
| Yang, TC | 1 |
| Wei, HJ | 1 |
| Hsu, JC | 1 |
| Lin, CL | 1 |
| Sorokina, EG | 2 |
| Semenova, ZhB | 2 |
| Bazarnaya, NA | 1 |
| Meshcheryakov, SV | 1 |
| Reutov, VP | 2 |
| Goryunova, AV | 1 |
| Pinelis, VG | 2 |
| Granstrem, OK | 2 |
| Roshal, LM | 1 |
| Yu, G | 1 |
| Dymond, M | 1 |
| Yuan, L | 1 |
| Chaturvedi, LS | 1 |
| Shiratsuchi, H | 1 |
| Durairaj, S | 1 |
| Marsh, HM | 1 |
| Basson, MD | 1 |
| Tisdall, MM | 1 |
| Rejdak, K | 2 |
| Kitchen, ND | 1 |
| Smith, M | 2 |
| Petzold, A | 2 |
| Tuzgen, S | 1 |
| Tanriover, N | 1 |
| Uzan, M | 1 |
| Tureci, E | 1 |
| Tanriverdi, T | 1 |
| Gumustas, K | 1 |
| Kuday, C | 1 |
| Sharpe, MA | 1 |
| Keir, G | 1 |
| Stelmasiak, Z | 1 |
| Thompson, EJ | 1 |
| Giovannoni, G | 1 |
| Hlatky, R | 1 |
| Goodman, JC | 2 |
| Valadka, AB | 1 |
| Robertson, CS | 2 |
| Atan, MS | 1 |
| Moochhala, SM | 1 |
| Ng, KC | 1 |
| Low, K | 1 |
| Teo, AL | 1 |
| Lu, J | 1 |
| Deng, Y | 1 |
| Thompson, BM | 1 |
| Gao, X | 1 |
| Hall, ED | 2 |
| Bayir, H | 1 |
| Kagan, VE | 1 |
| Janesko-Feldman, K | 1 |
| Rafikov, R | 1 |
| Huang, Z | 1 |
| Zhang, X | 1 |
| Vagni, V | 1 |
| Billiar, TR | 1 |
| Bazarnaia, NA | 1 |
| Meshcheriakov, SV | 1 |
| Goriunova, AV | 1 |
| Roshal', LM | 1 |
| Ansari, MA | 1 |
| Roberts, KN | 1 |
| Scheff, SW | 1 |
| Beckman, JS | 1 |
| Rao, AM | 1 |
| Dogan, A | 1 |
| Hatcher, JF | 1 |
| Dempsey, RJ | 1 |
| Mésenge, C | 1 |
| Charriaut-Marlangue, C | 1 |
| Verrecchia, C | 1 |
| Allix, M | 1 |
| Boulu, RR | 1 |
| Plotkine, M | 1 |
| Koedel, U | 1 |
| Pfister, HW | 1 |
| Kupina, NC | 1 |
| Althaus, JS | 1 |
| Cherian, L | 1 |
| Görlach, C | 1 |
| Hortobágyi, T | 1 |
| Benyó, Z | 1 |
| Wahl, M | 1 |
| Stoffel, M | 1 |
| Rinecker, M | 1 |
| Graf, R | 1 |
| Baethmann, A | 1 |
| Plesnila, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453] | 150 participants (Actual) | Observational | 2021-08-18 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitrates and Brain Injuries
| Article | Year |
|---|---|
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury.
Topics: Animals; Brain; Brain Injuries; Humans; Hydroxyl Radical; Nitrates; Nitric Oxide; Superoxide Dismuta | 1994 |
Oxidative stress in bacterial meningitis.
Topics: Animals; Brain Injuries; Host-Parasite Interactions; Humans; Lipid Peroxidation; Meningitis, Bacteri | 1999 |
3 trials available for nitrates and Brain Injuries
| Article | Year |
|---|---|
Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury.
Topics: Adolescent; Arginine; Brain Injuries; Case-Control Studies; Cerebrospinal Fluid; Child; Child, Presc | 2013 |
Levels of F2-isoprostanes, F4-neuroprostanes, and total nitrate/nitrite in plasma and cerebrospinal fluid of patients with traumatic brain injury.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Biomarkers; Brain Injuries; Chromatography, Gas; | 2015 |
The prognostic value of brain extracellular fluid nitric oxide metabolites after traumatic brain injury.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Injuries; Extracellular Fluid; Feasibility Studies | 2013 |
18 other studies available for nitrates and Brain Injuries
| Article | Year |
|---|---|
Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke.
Topics: Animals; Aquaporin 1; Brain Edema; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Di | 2017 |
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Hum | 2019 |
Autoantibodies to glutamate receptors and products of nitric oxide metabolism in serum in children in the acute phase of craniocerebral trauma.
Topics: Autoantibodies; Brain Injuries; Child; Female; Glasgow Coma Scale; Humans; Male; Nitrates; Nitric Ox | 2009 |
Propofol's effects on phagocytosis, proliferation, nitrate production, and cytokine secretion in pressure-stimulated microglial cells.
Topics: Anesthetics, Intravenous; Biological Assay; Brain Injuries; Cell Division; Cell Line; Cytokines; Hum | 2011 |
Nitric oxide levels in rat cortex, hippocampus, cerebellum, and brainstem after impact acceleration head injury.
Topics: Animals; Brain Chemistry; Brain Injuries; Brain Stem; Cerebellum; Cerebral Cortex; Hippocampus; Male | 2003 |
Serum and urine nitrate and nitrite are not reliable indicators of intrathecal nitric oxide production in acute brain injury.
Topics: Adult; Aged; Brain Injuries; Female; Humans; Linear Models; Male; Middle Aged; Nitrates; Nitric Oxid | 2003 |
Role of nitric oxide in cerebral blood flow abnormalities after traumatic brain injury.
Topics: Adult; Brain; Brain Injuries; Cerebrovascular Circulation; Female; Humans; Male; Microdialysis; Nitr | 2003 |
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; | 2004 |
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Pe | 2007 |
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
Topics: Adolescent; Adult; Aged; Animals; Brain; Brain Injuries; Chemotaxis, Leukocyte; Encephalitis; Enzyme | 2007 |
[Autoantibodies to glutamate receptors and metabolic products of nitric oxide in blood serum of children in the acute period of brain trauma].
Topics: Autoantibodies; Brain Injuries; Child; Female; Glasgow Coma Scale; Humans; Male; Nitrates; Nitric Ox | 2008 |
Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury.
Topics: Animals; Brain Injuries; Cell Death; Glutathione; Glutathione Disulfide; Hippocampus; Lipid Peroxida | 2008 |
Fluorometric assay of nitrite and nitrate in brain tissue after traumatic brain injury and cerebral ischemia.
Topics: 2-Naphthylamine; 4-Hydroxycoumarins; Animals; Brain Chemistry; Brain Injuries; Gerbillinae; Ischemic | 1998 |
Reduction of tyrosine nitration after N(omega)-nitro-L-arginine-methylester treatment of mice with traumatic brain injury.
Topics: Animals; Brain Injuries; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Male; Mice; NG-Ni | 1998 |
Peroxynitrite scavengers for the acute treatment of traumatic brain injury.
Topics: Animals; Brain Injuries; Chelating Agents; Drug Evaluation, Preclinical; Male; Mice; Nitrates; Penic | 1999 |
Brain nitric oxide changes after controlled cortical impact injury in rats.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Enzyme Inhibitors; Ext | 2000 |
Aminoguanidine reduces brain lesion volume after cold injury in the rat.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cold Temperature; Enzyme Inhibitors; Guanidines; Mal | 2000 |
Nitric oxide in the penumbra of a focal cortical necrosis in rats.
Topics: Animals; Brain Injuries; Cerebral Cortex; Cold Temperature; Extracellular Space; Male; Microdialysis | 2002 |