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nitrates and Angina Pectoris, Stable

nitrates has been researched along with Angina Pectoris, Stable in 20 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
" In the current study, we investigate whether oral sodium nitrate treatment will improve myocardial ischemia in patients with stable angina."5.22A randomized double-blind placebo-controlled crossover trial of sodium nitrate in patients with stable angina INAS. ( Ahmad, S; Bruce, M; Dawson, DK; Feelisch, M; Frenneaux, MP; Horowitz, J; Minnion, M; Parasuraman, SK; Schwarz, K; Shepstone, L; Singh, S, 2016)
"The main aims of therapy in chronic stable angina are to reduce the risk of myocardial infarction and death and improve symptoms and quality of life (QoL)."3.11Quality of Life Assessment in Trials of Revascularization for Chronic Stable Angina: Insights from ORBITA and the Implications of Blinding. ( Al-Lamee, RK; Francis, DP; Nowbar, AN, 2022)
"Ivabradine may be valuable for tailoring early antianginal treatment when used in combination with beta-blockers for chronic stable angina inadequately controlled by beta-blockers."2.82Efficacy and Safety of Ivabradine in Combination with Beta-Blockers in Patients with Stable Angina Pectoris: A Systematic Review and Meta-analysis. ( Karpov, Y; Nedoshivin, A; Petrova, PTS, 2022)
"ADDITIONS (prActical Daily efficacy anD safety of Procoralan® In combinaTION with betablockerS) was a multicenter, 4-month, noninterventional, prospective, open-label trial that involved stable-angina patients."2.82Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial. ( Ebelt, H; Höpfner, F; Müller-Werdan, U; Nuding, S; Stöckl, G; Werdan, K, 2016)
"Long-term nitrate treatment of stable angina is associated with side effects that can interfere with health-related quality of life (HRQoL) and medication adherence."2.79Effect of nitrate withdrawal on quality of life and adherence to treatment in patients with stable angina: evidence from a randomized clinical trial. ( Cruz, LN; Lemos, KF; Polanczyk, CA; Rabelo-Silva, ER; Ribeiro, LW, 2014)
"Clinical trials have proven the anti-anginal and anti-ischemic efficacy of the pacemaker current inhibitor ivabradine in combination with beta-blockers in patients with stable angina pectoris (AP)."2.79Ivabradine in combination with beta-blocker reduces symptoms and improves quality of life in elderly patients with stable angina pectoris: age-related results from the ADDITIONS study. ( Ebelt, H; Höpfner, F; Müller-Werdan, U; Nuding, S; Stöckl, G; Werdan, K, 2014)
" Compared with nitrates, the percentage of patients with adverse events significantly decreased when prescribed with compound salvia pellet (3."2.61Compound salvia pellet might be more effective and safer for chronic stable angina pectoris compared with nitrates: A systematic review and meta-analysis of randomized controlled trials. ( Hugang, J; Huiping, W; Jiao, L; Pei, J; Shian, Z; Yingdong, L; Yu, W; Zheng, W, 2019)
"Nitrates have been used to treat symptoms of chronic stable angina for over 135 years."2.53Vasodilator Therapy: Nitrates and Nicorandil. ( Kaski, JC; Tarkin, JM, 2016)
"Trimetazidine (TMZ) has been shown to reduce angina symptoms and to increase exercise capacity in randomized clinical trials, but more extensive data would be useful to assess its effects in real-world clinical practice and in patients with different durations of disease."1.48The Effectiveness of Trimetazidine Treatment in Patients with Stable Angina Pectoris of Various Durations: Results from the CHOICE-2 Study. ( Glezer, M, 2018)
"Ivabradine is an effective and well-tolerated anti-anginal treatment in patients with stable angina after PCI."1.42Ivabradine in combination with Beta-blockers in patients with chronic stable angina after percutaneous coronary intervention. ( Ebelt, H; Höpfner, F; Müller-Werdan, U; Nuding, S; Stöckl, G; Werdan, K, 2015)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's16 (80.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Nedoshivin, A1
Petrova, PTS1
Karpov, Y1
Knuuti, J1
Wijns, W1
Funck-Brentano, C1
Kallistratos, MS1
Poulimenos, LE1
Manolis, AJ1
Nowbar, AN1
Francis, DP1
Al-Lamee, RK1
Glezer, M1
Huiping, W1
Yu, W1
Pei, J1
Jiao, L1
Shian, Z1
Hugang, J1
Zheng, W1
Yingdong, L1
Rutherford, E1
Struthers, AD1
Lemos, KF1
Rabelo-Silva, ER1
Ribeiro, LW1
Cruz, LN1
Polanczyk, CA1
Valgimigli, M1
Biscaglia, S1
Khera, S1
Kolte, D1
Aronow, WS1
Müller-Werdan, U3
Stöckl, G3
Ebelt, H3
Nuding, S3
Höpfner, F3
Werdan, K3
Rognoni, A1
Ohman, EM1
Tarkin, JM1
Kaski, JC1
Schwarz, K1
Singh, S1
Parasuraman, SK1
Bruce, M1
Shepstone, L1
Feelisch, M1
Minnion, M1
Ahmad, S1
Horowitz, J1
Dawson, DK1
Frenneaux, MP1
Rathod, KS1
Jones, DA1
Van-Eijl, TJ1
Tsang, H1
Warren, H1
Hamshere, SM1
Kapil, V1
Jain, AK1
Deaner, A1
Poulter, N1
Caulfield, MJ1
Mathur, A1
Ahluwalia, A1
Di Monaco, A1
Sestito, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris: Randomised, Double Blind, Placebo Controlled Trial[NCT04270071]Phase 480 participants (Anticipated)Interventional2020-12-31Not yet recruiting
The Effects of Inorganic Nitrate on Cardiac Muscle: Physiology, Pharmacology and Therapeutic Potential in Patients Suffering From Angina[NCT02078921]Phase 270 participants (Anticipated)Interventional2012-10-31Completed
NITRATE-OCT-CIN Trial: A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina (Sub-study of the NITRATE-OCT Trial)[NCT05544981]300 participants (Actual)Interventional2016-01-02Completed
A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina[NCT02529189]Phase 2300 participants (Anticipated)Interventional2015-11-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for nitrates and Angina Pectoris, Stable

ArticleYear
Efficacy and Safety of Ivabradine in Combination with Beta-Blockers in Patients with Stable Angina Pectoris: A Systematic Review and Meta-analysis.
    Advances in therapy, 2022, Volume: 39, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Stable; Benzazepines; Cardiovascular Agents; Drug Therapy, Comb

2022
Compound salvia pellet might be more effective and safer for chronic stable angina pectoris compared with nitrates: A systematic review and meta-analysis of randomized controlled trials.
    Medicine, 2019, Volume: 98, Issue:9

    Topics: Angina, Stable; Drug Implants; Drugs, Chinese Herbal; Humans; Nitrates; Phytotherapy; Randomized Con

2019
Stable angina pectoris.
    Current atherosclerosis reports, 2014, Volume: 16, Issue:7

    Topics: Acetanilides; Angina, Stable; Benzazepines; Coronary Artery Bypass; Coronary Artery Disease; Coronar

2014
CLINICAL PRACTICE. Chronic Stable Angina.
    The New England journal of medicine, 2016, Mar-24, Volume: 374, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Stable; Calcium Channel Blockers; Coronary Artery Disease

2016
Vasodilator Therapy: Nitrates and Nicorandil.
    Cardiovascular drugs and therapy, 2016, Volume: 30, Issue:4

    Topics: Angina, Stable; Humans; Nicorandil; Nitrates; Nitric Oxide Donors; Vasodilator Agents

2016
The patient with chronic ischemic heart disease. Role of ranolazine in the management of stable angina.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:12

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina, Stable; Angiotensin-Converting Enzyme Inhibitors;

2012

Trials

6 trials available for nitrates and Angina Pectoris, Stable

ArticleYear
Quality of Life Assessment in Trials of Revascularization for Chronic Stable Angina: Insights from ORBITA and the Implications of Blinding.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:5

    Topics: Angina, Stable; Canada; Humans; Myocardial Infarction; Nitrates; Percutaneous Coronary Intervention;

2022
Effect of nitrate withdrawal on quality of life and adherence to treatment in patients with stable angina: evidence from a randomized clinical trial.
    Coronary artery disease, 2014, Volume: 25, Issue:3

    Topics: Aged; Angina, Stable; Cardiovascular Agents; Female; Humans; Male; Medication Adherence; Middle Aged

2014
Ivabradine in combination with beta-blocker reduces symptoms and improves quality of life in elderly patients with stable angina pectoris: age-related results from the ADDITIONS study.
    Experimental gerontology, 2014, Volume: 59

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angina, Stable; Benzazepines; Blood Pressure;

2014
Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial.
    Cardiology, 2016, Volume: 133, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Angina, Stable; Benzazepines; Cardi

2016
A randomized double-blind placebo-controlled crossover trial of sodium nitrate in patients with stable angina INAS.
    Future cardiology, 2016, Volume: 12, Issue:6

    Topics: Administration, Oral; Aged; Angina, Stable; Cross-Over Studies; Double-Blind Method; Exercise Test;

2016
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
    BMJ open, 2016, 12-20, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat

2016
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
    BMJ open, 2016, 12-20, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat

2016
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
    BMJ open, 2016, 12-20, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat

2016
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
    BMJ open, 2016, 12-20, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat

2016

Other Studies

8 other studies available for nitrates and Angina Pectoris, Stable

ArticleYear
Anti-ischaemic medication must be adapted to each patient's characteristics and preferences in patients with chronic coronary syndromes.
    European heart journal, 2020, 01-14, Volume: 41, Issue:3

    Topics: Angina, Stable; Calcium Channel Blockers; Humans; Hypotension; Nitrates; Syndrome

2020
Beta blockers, calcium channel blockers, and long-acting nitrates for patients with stable angina and low blood pressure levels: should this recommendation be reconsidered?
    European heart journal, 2020, 01-14, Volume: 41, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina, Stable; Calcium Channel Blockers; Humans; Hypotension; Nitrates

2020
The Effectiveness of Trimetazidine Treatment in Patients with Stable Angina Pectoris of Various Durations: Results from the CHOICE-2 Study.
    Advances in therapy, 2018, Volume: 35, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Stable; Angiotensin Receptor Antagonists; Angiotensin-Con

2018
Pentaerythrityl tetranitrate (PETN): a better nitrate?
    European heart journal, 2019, 12-07, Volume: 40, Issue:46

    Topics: Angina, Stable; Double-Blind Method; Humans; Nitrates; Pentaerythritol Tetranitrate; Vasodilator Age

2019
Use of ranolazine in patients with stable angina pectoris.
    Cardiology, 2014, Volume: 128, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina, Stable; Calcium Channel Blockers; Delayed-Action

2014
Ivabradine in combination with Beta-blockers in patients with chronic stable angina after percutaneous coronary intervention.
    Advances in therapy, 2015, Volume: 32, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Stable; Benzazepines; Canada; Cardiovascular Agents; Drug

2015
Old and New Drugs for Treatment of Stable Angina.
    Cardiovascular & hematological agents in medicinal chemistry, 2015, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Angina, Stable; Calcium Channel Blockers; Cardiovascular Agents; Drug D

2015
[Trimetazidine addition to antianginal therapy: effects on efficacy and quality of life in patients with stable angina treated outpatiently].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Angina, Stable; Drug Therapy, Combination; Drugs, Generic; Female; Hum

2012