Page last updated: 2024-10-19

nitrates and Acute Brain Injuries

nitrates has been researched along with Acute Brain Injuries in 23 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"Moreover, MN-08 also alleviated cerebral vasospasm in a cisterna magna single-injection model in rabbits."1.51The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models. ( Guo, B; Han, Y; Ju, J; Li, N; Li, S; Liu, Z; Luo, F; Mak, S; Sun, Y; Wang, Y; Wu, L; Yang, X; Zhang, G; Zhang, Z; Zhou, Q; Zhu, Z, 2019)
"Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion."1.46Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke. ( Darabi, S; Mohammadi, MT, 2017)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (21.74)18.2507
2000's12 (52.17)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Darabi, S1
Mohammadi, MT1
Luo, F1
Wu, L1
Zhang, Z2
Zhu, Z1
Liu, Z1
Guo, B1
Li, N1
Ju, J1
Zhou, Q1
Li, S1
Yang, X1
Mak, S1
Han, Y1
Sun, Y1
Wang, Y1
Zhang, G1
Thampatty, BP1
Klamerus, MM1
Oberly, PJ1
Feldman, KL1
Bell, MJ1
Tyler-Kabara, EC1
Adelson, PD1
Clark, RS2
Kochanek, PM2
Poloyac, SM1
Yen, HC1
Chen, TW1
Yang, TC1
Wei, HJ1
Hsu, JC1
Lin, CL1
Sorokina, EG2
Semenova, ZhB2
Bazarnaya, NA1
Meshcheryakov, SV1
Reutov, VP2
Goryunova, AV1
Pinelis, VG2
Granstrem, OK2
Roshal, LM1
Yu, G1
Dymond, M1
Yuan, L1
Chaturvedi, LS1
Shiratsuchi, H1
Durairaj, S1
Marsh, HM1
Basson, MD1
Tisdall, MM1
Rejdak, K2
Kitchen, ND1
Smith, M2
Petzold, A2
Tuzgen, S1
Tanriover, N1
Uzan, M1
Tureci, E1
Tanriverdi, T1
Gumustas, K1
Kuday, C1
Sharpe, MA1
Keir, G1
Stelmasiak, Z1
Thompson, EJ1
Giovannoni, G1
Hlatky, R1
Goodman, JC2
Valadka, AB1
Robertson, CS2
Atan, MS1
Moochhala, SM1
Ng, KC1
Low, K1
Teo, AL1
Lu, J1
Deng, Y1
Thompson, BM1
Gao, X1
Hall, ED2
Bayir, H1
Kagan, VE1
Janesko-Feldman, K1
Rafikov, R1
Huang, Z1
Zhang, X1
Vagni, V1
Billiar, TR1
Bazarnaia, NA1
Meshcheriakov, SV1
Goriunova, AV1
Roshal', LM1
Ansari, MA1
Roberts, KN1
Scheff, SW1
Beckman, JS1
Rao, AM1
Dogan, A1
Hatcher, JF1
Dempsey, RJ1
Mésenge, C1
Charriaut-Marlangue, C1
Verrecchia, C1
Allix, M1
Boulu, RR1
Plotkine, M1
Koedel, U1
Pfister, HW1
Kupina, NC1
Althaus, JS1
Cherian, L1
Görlach, C1
Hortobágyi, T1
Benyó, Z1
Wahl, M1
Stoffel, M1
Rinecker, M1
Graf, R1
Baethmann, A1
Plesnila, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury[NCT04951453]150 participants (Actual)Observational2021-08-18Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for nitrates and Acute Brain Injuries

ArticleYear
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Animals; Brain; Brain Injuries; Humans; Hydroxyl Radical; Nitrates; Nitric Oxide; Superoxide Dismuta

1994
Oxidative stress in bacterial meningitis.
    Brain pathology (Zurich, Switzerland), 1999, Volume: 9, Issue:1

    Topics: Animals; Brain Injuries; Host-Parasite Interactions; Humans; Lipid Peroxidation; Meningitis, Bacteri

1999

Trials

3 trials available for nitrates and Acute Brain Injuries

ArticleYear
Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013, Volume: 14, Issue:4

    Topics: Adolescent; Arginine; Brain Injuries; Case-Control Studies; Cerebrospinal Fluid; Child; Child, Presc

2013
Levels of F2-isoprostanes, F4-neuroprostanes, and total nitrate/nitrite in plasma and cerebrospinal fluid of patients with traumatic brain injury.
    Free radical research, 2015, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Biomarkers; Brain Injuries; Chromatography, Gas;

2015
The prognostic value of brain extracellular fluid nitric oxide metabolites after traumatic brain injury.
    Neurocritical care, 2013, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Injuries; Extracellular Fluid; Feasibility Studies

2013

Other Studies

18 other studies available for nitrates and Acute Brain Injuries

ArticleYear
Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke.
    Brain injury, 2017, Volume: 31, Issue:8

    Topics: Animals; Aquaporin 1; Brain Edema; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Di

2017
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
    British journal of pharmacology, 2019, Volume: 176, Issue:17

    Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Hum

2019
Autoantibodies to glutamate receptors and products of nitric oxide metabolism in serum in children in the acute phase of craniocerebral trauma.
    Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:4

    Topics: Autoantibodies; Brain Injuries; Child; Female; Glasgow Coma Scale; Humans; Male; Nitrates; Nitric Ox

2009
Propofol's effects on phagocytosis, proliferation, nitrate production, and cytokine secretion in pressure-stimulated microglial cells.
    Surgery, 2011, Volume: 150, Issue:5

    Topics: Anesthetics, Intravenous; Biological Assay; Brain Injuries; Cell Division; Cell Line; Cytokines; Hum

2011
Nitric oxide levels in rat cortex, hippocampus, cerebellum, and brainstem after impact acceleration head injury.
    Neurological research, 2003, Volume: 25, Issue:1

    Topics: Animals; Brain Chemistry; Brain Injuries; Brain Stem; Cerebellum; Cerebral Cortex; Hippocampus; Male

2003
Serum and urine nitrate and nitrite are not reliable indicators of intrathecal nitric oxide production in acute brain injury.
    Journal of the neurological sciences, 2003, Apr-15, Volume: 208, Issue:1-2

    Topics: Adult; Aged; Brain Injuries; Female; Humans; Linear Models; Male; Middle Aged; Nitrates; Nitric Oxid

2003
Role of nitric oxide in cerebral blood flow abnormalities after traumatic brain injury.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:5

    Topics: Adult; Brain; Brain Injuries; Cerebrovascular Circulation; Female; Humans; Male; Microdialysis; Nitr

2003
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
    Journal of neurosurgery, 2004, Volume: 101, Issue:1

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal;

2004
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
    Experimental neurology, 2007, Volume: 205, Issue:1

    Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Pe

2007
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
    Journal of neurochemistry, 2007, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Brain; Brain Injuries; Chemotaxis, Leukocyte; Encephalitis; Enzyme

2007
[Autoantibodies to glutamate receptors and metabolic products of nitric oxide in blood serum of children in the acute period of brain trauma].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:3

    Topics: Autoantibodies; Brain Injuries; Child; Female; Glasgow Coma Scale; Humans; Male; Nitrates; Nitric Ox

2008
Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury.
    Free radical biology & medicine, 2008, Aug-15, Volume: 45, Issue:4

    Topics: Animals; Brain Injuries; Cell Death; Glutathione; Glutathione Disulfide; Hippocampus; Lipid Peroxida

2008
Fluorometric assay of nitrite and nitrate in brain tissue after traumatic brain injury and cerebral ischemia.
    Brain research, 1998, May-18, Volume: 793, Issue:1-2

    Topics: 2-Naphthylamine; 4-Hydroxycoumarins; Animals; Brain Chemistry; Brain Injuries; Gerbillinae; Ischemic

1998
Reduction of tyrosine nitration after N(omega)-nitro-L-arginine-methylester treatment of mice with traumatic brain injury.
    European journal of pharmacology, 1998, Jul-17, Volume: 353, Issue:1

    Topics: Animals; Brain Injuries; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Male; Mice; NG-Ni

1998
Peroxynitrite scavengers for the acute treatment of traumatic brain injury.
    Annals of the New York Academy of Sciences, 1999, Volume: 890

    Topics: Animals; Brain Injuries; Chelating Agents; Drug Evaluation, Preclinical; Male; Mice; Nitrates; Penic

1999
Brain nitric oxide changes after controlled cortical impact injury in rats.
    Journal of neurophysiology, 2000, Volume: 83, Issue:4

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Enzyme Inhibitors; Ext

2000
Aminoguanidine reduces brain lesion volume after cold injury in the rat.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:2

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cold Temperature; Enzyme Inhibitors; Guanidines; Mal

2000
Nitric oxide in the penumbra of a focal cortical necrosis in rats.
    Neuroscience letters, 2002, May-24, Volume: 324, Issue:3

    Topics: Animals; Brain Injuries; Cerebral Cortex; Cold Temperature; Extracellular Space; Male; Microdialysis

2002
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