Page last updated: 2024-09-03

nitisinone and Disease Exacerbation

nitisinone has been researched along with Disease Exacerbation in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barton, GJ; Briggs, M; Cox, TF; Daroszewska, A; Davison, AS; Devine, JM; Dillon, JP; Fisher, M; Gallagher, JA; Griffin, R; Harrold, J; Hughes, AT; Hughes, G; Jarvis, JC; Jones, A; Judd, S; Khedr, M; Loftus, N; McCormick, M; Milan, AM; Psarelli, EE; Ranganath, LR; Sireau, N; Taylor, S; Usher, JL; Vinjamuri, S; West, E1
Adam, D1
Bendadi, F; de Koning, TJ; de Sain, MG; Prinsen, HC; Sinnema, G; van Hasselt, PM; van Spronsen, FJ; Verhoeven-Duif, N; Visser, G1
Cox, TF; Ranganath, LR1
Anderson, PD; Anikster, Y; Bernardini, I; Fitzpatrick, DL; Gahl, WA; Gerber, LH; Huizing, M; Introne, WJ; Murphey, MD; Perry, MB; Phornphutkul, C1
Kobrinsky, NL; Sjolander, DE1

Other Studies

6 other study(ies) available for nitisinone and Disease Exacerbation

ArticleYear
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.
    Molecular genetics and metabolism, 2018, Volume: 125, Issue:1-2

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Cyclohexanones; Disease Progression; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; United Kingdom

2018
A father's fight to help his sons - and fix clinical trials.
    Nature, 2019, Volume: 565, Issue:7738

    Topics: Adolescent; Alkaptonuria; Animals; Autopsy; Child; Clinical Trials as Topic; Compassionate Use Trials; Cyclohexanones; Disease Models, Animal; Disease Progression; Drug Approval; Endpoint Determination; Female; Homogentisic Acid; Humans; Infant; Male; Mice; National Health Programs; National Institutes of Health (U.S.); Nitrobenzoates; Observational Studies as Topic; Off-Label Use; Orphan Drug Production; Rare Diseases; Rats; Sample Size; Tyrosine; Tyrosinemias; United States; United States Food and Drug Administration

2019
Impaired cognitive functioning in patients with tyrosinemia type I receiving nitisinone.
    The Journal of pediatrics, 2014, Volume: 164, Issue:2

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Child; Child Development; Child, Preschool; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Cyclohexanones; Disease Progression; Enzyme Inhibitors; Female; Humans; Incidence; Male; Netherlands; Nitrobenzoates; Prognosis; Risk Factors; Tyrosinemias; Young Adult

2014
Natural history of alkaptonuria revisited: analyses based on scoring systems.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:6

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Aged; Aged, 80 and over; Alkaptonuria; Arthralgia; Arthritis; Cartilage, Articular; Causality; Cohort Studies; Comorbidity; Cyclohexanones; Disease Progression; Female; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Ochronosis; Pain; Surveys and Questionnaires

2011
Natural history of alkaptonuria.
    The New England journal of medicine, 2002, Dec-26, Volume: 347, Issue:26

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Alkaptonuria; Child; Child, Preschool; Connective Tissue Diseases; Cyclohexanones; Dioxygenases; Disease Progression; DNA Mutational Analysis; Enzyme Inhibitors; Female; Heart Valve Diseases; Homogentisate 1,2-Dioxygenase; Humans; Joint Diseases; Kidney Calculi; Life Tables; Linear Models; Longitudinal Studies; Male; Middle Aged; Mutation; Nitrobenzoates; Oxygenases; Severity of Illness Index; Tyrosine

2002
Response of metastatic recurrent neuroblastoma to nitisinone: a modulator of tyrosine metabolism.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Combined Modality Therapy; Cyclohexanones; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Fatal Outcome; Humans; Male; Neoplasm Recurrence, Local; Neuroblastoma; Nitrobenzoates; Remission Induction; Treatment Outcome; Tyrosine

2006