Page last updated: 2024-09-03

nitisinone and Cancer of Liver

nitisinone has been researched along with Cancer of Liver in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's9 (39.13)29.6817
2010's7 (30.43)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Aktuglu Zeybek, AC; Cansever, MS; Erel, O; Iscan, HZ; Kiykim, E; Neselioglu, S; Zubarioglu, T1
Balouch, F; Bhushan, S; Ee, L; Hodgkinson, P; Lampe, G; Lewindon, P; McGill, J; Noble, C1
Bou-Gharios, G; Casimir, G; Claes, P; Colemonts-Vroninks, H; De Kock, J; Gallagher, JA; Goyens, P; Heymans, A; Hughes, JH; Lequeue, S; Marcélis, L; Martens, GA; Neuckermans, J; Vanhaecke, T1
Almuqbil, M; Chinsky, JM; Knoll, J1
Hakeem, A; Jalan, A; Menon, J; Reddy, MS; Rela, M; Shanmugam, N; Valamparampil, JJ; Vij, M1
Pennings, JP; van Ginkel, WG; van Spronsen, FJ1
Mitchell, GA; Yang, H1
Aydogdu, S; Farajov, R; Iakobadze, Z; Karaca, CA; Kilic, M; Yilmaz, C1
Janovszky, A; Karg, E; László, A; Rózsa, M; Sallay, E; Tiszlavicz, L; Túri, S; Ugarte, M; Várkonyi, A; Wittmann, G1
Chapchap, P; Feier, FH; Fonseca, EA; Leite, KM; Miura, IK; Porta, A; Porta, G; Pugliese, R; Seda Neto, J1
Finegold, M; Grompe, M; Lee, AY; Rothfuss, A; Sharma, AD; Vogel, A; Wang, Z; Willenbring, H1
Buitrago-Molina, LE; Cañón, JM; Finegold, M; Geffers, R; Grompe, M; Lamlé, J; Manns, MP; Marhenke, S; Sporn, M; Vogel, A; Yamamoto, M1
Callea, F; Castellano, A; Dionisi-Vici, C; Francalanci, P; Holme, E; Jenkner, A; Nobili, V1
Arias, C; Cabello, JF; Castro, G; Cornejo, V; de la Parra, A; Fernández, E; Raimann, E1
McKiernan, PJ1
Bijleveld, CM; Koelink, CJ; van den Heuvel-Eibrink, MM; van der Ploeg, A; van Hasselt, P; van Spronsen, FJ; Wijburg, FA1
Bergeron, A; Finegold, MJ; Jorquera, R; Langlois, C; Orejuela, D; Rhead, WJ; Tanguay, RM1
Bergeron, A; Finegold, MJ; Jorquera, R; Orejuela, D; Tanguay, RM1
Baumann, U; Santra, S1
al-Dhalimy, M; Finegold, M; Grompe, M; Kennaway, NG; Lindstedt, S; Ou, CN; Papaconstantinou, J; Torres-Ramos, CA1
Al-Dhalimy, M; Brantly, M; Finegold, M; Grompe, M; Ou, CN; Overturf, K; Tanguay, R1
Holme, E; Lindstedt, S1
González Pascual, E; Holme, E; Lambruschini Ferri, N; Mas Comas, A; Ros Viladoms, J; Vilaseca Buscà, MA1

Reviews

4 review(s) available for nitisinone and Cancer of Liver

ArticleYear
Liver Cancer in Tyrosinemia Type 1.
    Advances in experimental medicine and biology, 2017, Volume: 959

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Cyclohexanones; Early Detection of Cancer; Humans; Liver Neoplasms; Nitrobenzoates; Tyrosinemias

2017
Remaining Challenges in the Treatment of Tyrosinemia from the Clinician's Viewpoint.
    Advances in experimental medicine and biology, 2017, Volume: 959

    Topics: Animals; Cyclohexanones; Diet; Diet Therapy; Humans; Infant, Newborn; Kidney Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Neonatal Screening; Nitrobenzoates; Tyrosinemias

2017
Experience of nitisinone for the pharmacological treatment of hereditary tyrosinaemia type 1.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:7

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Carcinoma, Hepatocellular; Child; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Diseases; Liver Neoplasms; Monitoring, Physiologic; Nitrobenzoates; Tyrosinemias

2008
Nontransplant treatment of tyrosinemia.
    Clinics in liver disease, 2000, Volume: 4, Issue:4

    Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Humans; Infant; Liver Neoplasms; Nitrobenzoates; Risk Factors; Tyrosinemias

2000

Other Studies

19 other study(ies) available for nitisinone and Cancer of Liver

ArticleYear
Evaluation of dynamic thiol/disulfide homeostasis in hereditary tyrosinemia type 1 patients.
    Pediatric research, 2022, Volume: 92, Issue:2

    Topics: Carcinoma, Hepatocellular; Cyclohexanones; Disulfides; Homeostasis; Humans; Liver Neoplasms; Nitrobenzoates; Oxidative Stress; Sulfhydryl Compounds; Tyrosine; Tyrosinemias

2022
Hepatocellular carcinoma requiring liver transplantation in hereditary tyrosinemia type 1 despite nitisinone therapy and α1-fetoprotein normalization.
    Pediatric transplantation, 2022, Volume: 26, Issue:7

    Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Child; Cyclohexanones; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Nitrobenzoates; Tyrosinemias

2022
Hereditary Tyrosinemia Type 1 Mice under Continuous Nitisinone Treatment Display Remnants of an Uncorrected Liver Disease Phenotype.
    Genes, 2023, 03-11, Volume: 14, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mice; Phenotype; Tyrosine; Tyrosinemias

2023
Late Development of Hepatocellular Carcinoma in Tyrosinemia Type 1 Despite Nitisinone (NTBC) Treatment.
    Journal of pediatric gastroenterology and nutrition, 2020, Volume: 71, Issue:2

    Topics: Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Neoplasms; Nitrobenzoates; Tyrosinemias

2020
Liver Transplantation: A Safe and Definitive Alternative to Lifelong Nitisinone for Tyrosinemia Type 1.
    Indian journal of pediatrics, 2022, Volume: 89, Issue:5

    Topics: Carcinoma, Hepatocellular; Child; Cyclohexanones; Humans; Liver Neoplasms; Liver Transplantation; Nitrobenzoates; Retrospective Studies; Treatment Outcome; Tyrosinemias

2022
Live donor liver transplantation for type 1 tyrosinemia: An analysis of 15 patients.
    Pediatric transplantation, 2019, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclohexanones; Databases, Factual; Female; Humans; Infant; Infant, Newborn; Liver Neoplasms; Liver Transplantation; Living Donors; Male; Neonatal Screening; Nitrobenzoates; Retrospective Studies; Treatment Outcome; Tyrosinemias

2019
The fate of tyrosinaemic Hungarian patients before the NTBC aera.
    Ideggyogyaszati szemle, 2013, Nov-30, Volume: 66, Issue:11-12

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Fatal Outcome; Homozygote; Humans; Hungary; Hydrolases; Kidney Neoplasms; Liver Neoplasms; Male; Nitrobenzoates; Treatment Outcome; Tyrosine; Tyrosinemias

2013
HCC prevalence and histopathological findings in liver explants of patients with hereditary tyrosinemia type 1.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:9

    Topics: Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclohexanones; Drug Resistance; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infant; Liver; Liver Neoplasms; Liver Transplantation; Male; Nitrobenzoates; Prognosis; Retrospective Studies; Tomography, X-Ray Computed; Tyrosinemias

2014
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis.
    Cancer cell, 2008, Jul-08, Volume: 14, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Hepatectomy; Hepatocytes; Hydrolases; Kidney Diseases, Cystic; Kidney Neoplasms; Kidney Tubules, Proximal; Liver Neoplasms; Liver Regeneration; Mice; Mice, Knockout; Neoplasms; Nitrobenzoates; Tyrosinemias

2008
Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:2

    Topics: Animals; Cyclohexanones; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Hepatitis; Hydrolases; Imidazoles; Inactivation, Metabolic; Liver; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Mice; Mice, Knockout; NF-E2-Related Factor 2; Nitrobenzoates; Oleanolic Acid; Oxidative Stress; Tyrosinemias

2008
Tyrosinemia type 1: metastatic hepatoblastoma with a favorable outcome.
    Pediatrics, 2010, Volume: 126, Issue:1

    Topics: Adolescent; Biopsy, Needle; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Cyclohexanones; Diagnosis, Differential; Female; Follow-Up Studies; Hepatectomy; Hepatoblastoma; Humans; Immunohistochemistry; Liver Neoplasms; Nitrobenzoates; Risk Assessment; Treatment Outcome; Tyrosinemias

2010
[Clinical follow up of Chilean patients with tyrosinemia type 1 treated with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-ciclohexanedione (NTBC)].
    Revista medica de Chile, 2012, Volume: 140, Issue:2

    Topics: Child, Preschool; Chile; Cyclohexanones; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infant; Liver Neoplasms; Liver Transplantation; Male; Nitrobenzoates; Retrospective Studies; Time Factors; Treatment Outcome; Tyrosinemias

2012
Nitisinone in the treatment of hereditary tyrosinaemia type 1.
    Drugs, 2006, Volume: 66, Issue:6

    Topics: Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Kidney Diseases; Liver Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Monitoring, Physiologic; Nitrobenzoates; Tyrosine; Tyrosinemias

2006
Tyrosinemia type I treated by NTBC: how does AFP predict liver cancer?
    Molecular genetics and metabolism, 2006, Volume: 89, Issue:4

    Topics: alpha-Fetoproteins; Child; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Female; Humans; Infant; Liver Neoplasms; Male; Nitrobenzoates; Prognosis; Tyrosinemias

2006
Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment.
    Molecular genetics and metabolism, 2008, Volume: 93, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Drug Therapy, Combination; Female; Glutathione; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Oxidative Stress; Pregnancy; Tyrosinemias

2008
Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah-/- knockout mice model.
    Journal of hepatology, 2008, Volume: 48, Issue:2

    Topics: Animals; bcl-X Protein; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tyrosinemias

2008
Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.
    Nature genetics, 1995, Volume: 10, Issue:4

    Topics: alpha-Fetoproteins; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Heptanoates; Humans; Hydrolases; Liver; Liver Diseases; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Pancreas; RNA, Messenger; Tyrosine

1995
Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.
    Nature genetics, 1996, Volume: 12, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Cell Count; Cell Transplantation; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Genetic Therapy; Humans; Hydrolases; Immunoenzyme Techniques; Liver; Liver Function Tests; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Retroviridae; Tyrosine

1996
[Evolution of a case of tyrosinemia type I treated with NTBC].
    Anales espanoles de pediatria, 2001, Volume: 54, Issue:3

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Neoplasms; Male; Nitrobenzoates; Palliative Care; Tyrosinemias

2001