nitidine has been researched along with Liver Neoplasms in 9 studies
nitidine: RN given refers to parent cpd; synonym NSC 146397 refers to chloride; structure
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers." | 5.72 | The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma. ( Chen, G; Dang, YW; Du, XF; Gao, L; He, RQ; Huang, ZG; Lai, ZF; Li, JD; Li, MF; Li, SH; Liu, LM; Luo, JY; Xiong, DD; Yang, X; Zeng, JH, 2022) |
| "Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I." | 5.39 | Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013) |
| "Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers." | 1.72 | The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma. ( Chen, G; Dang, YW; Du, XF; Gao, L; He, RQ; Huang, ZG; Lai, ZF; Li, JD; Li, MF; Li, SH; Liu, LM; Luo, JY; Xiong, DD; Yang, X; Zeng, JH, 2022) |
| " Additionally, long-term use of these agents probably generates drug resistance and unacceptable adverse effects." | 1.40 | Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways. ( Chen, H; Liao, J; Lin, J; Liu, L; Peng, J; Shen, A; Xu, T, 2014) |
| "Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I." | 1.39 | Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S | 1 |
| Liao, Y | 1 |
| Lv, J | 1 |
| Hou, H | 1 |
| Feng, J | 1 |
| Gao, L | 4 |
| Xiong, DD | 5 |
| Yang, X | 4 |
| Li, JD | 4 |
| He, RQ | 4 |
| Huang, ZG | 4 |
| Lai, ZF | 4 |
| Liu, LM | 6 |
| Luo, JY | 3 |
| Du, XF | 3 |
| Zeng, JH | 3 |
| Li, MF | 3 |
| Li, SH | 3 |
| Dang, YW | 6 |
| Chen, G | 6 |
| Pang, YY | 1 |
| Yang, J | 1 |
| Wu, HY | 1 |
| Yang, LH | 1 |
| Shi, L | 1 |
| Mo, WJ | 1 |
| Tang, D | 1 |
| Lu, HP | 1 |
| Li, D | 2 |
| Liu, S | 1 |
| Zhu, J | 1 |
| Shen, L | 1 |
| Zhang, QY | 1 |
| Zhu, H | 1 |
| Lin, P | 2 |
| Yang, H | 2 |
| Liao, J | 2 |
| Xu, T | 2 |
| Zheng, JX | 1 |
| Lin, JM | 1 |
| Cai, QY | 1 |
| Yu, DB | 1 |
| Peng, J | 2 |
| Lin, J | 2 |
| Shen, A | 1 |
| Chen, H | 1 |
| Liu, L | 2 |
| Ou, X | 1 |
| Lu, Y | 1 |
| Liao, L | 1 |
| Liu, H | 1 |
| Xu, H | 1 |
9 other studies available for nitidine and Liver Neoplasms
| Article | Year |
|---|---|
Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; JNK Mitogen-Activated Protein Kinases; Liver | 2022 |
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA | 2022 |
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA | 2022 |
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA | 2022 |
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA | 2022 |
The clinical value and potential molecular mechanism of the downregulation of MAOA in hepatocellular carcinoma tissues.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Biomarkers, Tumor; Carcinoma, Hepa | 2020 |
Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; | 2021 |
DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride.
Topics: Animals; Benzophenanthridines; Biomarkers, Tumor; Disease-Free Survival; DNA Topoisomerases, Type I; | 2018 |
Gene profiling of HepG2 cells following nitidine chloride treatment: An investigation with microarray and Connectivity Mapping.
Topics: Animals; Apoptosis; Benzophenanthridines; Cell Proliferation; Gene Expression Regulation, Neoplastic | 2019 |
Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridi | 2013 |
Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridines; Cell | 2014 |
Nitidine chloride induces apoptosis in human hepatocellular carcinoma cells through a pathway involving p53, p21, Bax and Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridines; Carcinoma, Hepatocellular; Cas | 2015 |