Page last updated: 2024-11-01

nitidine and Hepatocellular Carcinoma

nitidine has been researched along with Hepatocellular Carcinoma in 7 studies

nitidine: RN given refers to parent cpd; synonym NSC 146397 refers to chloride; structure

Research Excerpts

ExcerptRelevanceReference
"Nitidine chloride (NC) has been demonstrated to have an anticancer effect in hepatocellular carcinoma (HCC)."7.91High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma. ( Chen, G; Dang, YW; Feng, ZB; Fu, HX; He, RQ; Lai, ZF; Liu, LM; Luo, DZ; Qin, Y; Wu, HY; Xiong, DD, 2019)
"Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers."5.72The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma. ( Chen, G; Dang, YW; Du, XF; Gao, L; He, RQ; Huang, ZG; Lai, ZF; Li, JD; Li, MF; Li, SH; Liu, LM; Luo, JY; Xiong, DD; Yang, X; Zeng, JH, 2022)
"Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I."5.39Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013)
"Nitidine chloride (NC) has been demonstrated to have an anticancer effect in hepatocellular carcinoma (HCC)."3.91High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma. ( Chen, G; Dang, YW; Feng, ZB; Fu, HX; He, RQ; Lai, ZF; Liu, LM; Luo, DZ; Qin, Y; Wu, HY; Xiong, DD, 2019)
"Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers."1.72The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma. ( Chen, G; Dang, YW; Du, XF; Gao, L; He, RQ; Huang, ZG; Lai, ZF; Li, JD; Li, MF; Li, SH; Liu, LM; Luo, JY; Xiong, DD; Yang, X; Zeng, JH, 2022)
"Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I."1.39Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Chen, S1
Liao, Y1
Lv, J1
Hou, H1
Feng, J1
Gao, L4
Xiong, DD5
Yang, X4
Li, JD4
He, RQ5
Huang, ZG4
Lai, ZF5
Liu, LM5
Luo, JY3
Du, XF3
Zeng, JH3
Li, MF3
Li, SH3
Dang, YW5
Chen, G5
Feng, ZB1
Qin, Y1
Fu, HX1
Wu, HY2
Luo, DZ1
Pang, YY1
Yang, J1
Yang, LH1
Shi, L1
Mo, WJ1
Tang, D1
Lu, HP1
Li, D2
Liu, S1
Zhu, J1
Shen, L1
Zhang, QY1
Zhu, H1
Liao, J1
Xu, T1
Zheng, JX1
Lin, JM1
Cai, QY1
Yu, DB1
Peng, J1
Ou, X1
Lu, Y1
Liao, L1
Liu, L1
Liu, H1
Xu, H1

Other Studies

7 other studies available for nitidine and Hepatocellular Carcinoma

ArticleYear
Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells.
    Planta medica, 2022, Volume: 88, Issue:13

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; JNK Mitogen-Activated Protein Kinases; Liver

2022
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
    BMC cancer, 2022, Dec-01, Volume: 22, Issue:1

    Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA

2022
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
    BMC cancer, 2022, Dec-01, Volume: 22, Issue:1

    Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA

2022
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
    BMC cancer, 2022, Dec-01, Volume: 22, Issue:1

    Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA

2022
The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.
    BMC cancer, 2022, Dec-01, Volume: 22, Issue:1

    Topics: Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mice; Mice, Nude; RNA

2022
High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma.
    Cell death & disease, 2019, 09-10, Volume: 10, Issue:9

    Topics: Animals; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromobox Protein Homolo

2019
The clinical value and potential molecular mechanism of the downregulation of MAOA in hepatocellular carcinoma tissues.
    Cancer medicine, 2020, Volume: 9, Issue:21

    Topics: Animals; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Biomarkers, Tumor; Carcinoma, Hepa

2020
Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma.
    BMC pharmacology & toxicology, 2021, 01-06, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carcinoma, Hepatocellular; Cell Line, Tumor;

2021
Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.
    International journal of molecular medicine, 2013, Volume: 32, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridi

2013
Nitidine chloride induces apoptosis in human hepatocellular carcinoma cells through a pathway involving p53, p21, Bax and Bcl-2.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridines; Carcinoma, Hepatocellular; Cas

2015