nitidine has been researched along with Disease Models, Animal in 5 studies
nitidine: RN given refers to parent cpd; synonym NSC 146397 refers to chloride; structure
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Psoriasis is a common dermatosis causing considerable inconvenience to 4% of the general population." | 5.51 | Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models. ( Bao, YL; Jiang, BW; Jing, QQ; Li, WJ; Li, YX; Liu, L; Liu, YC; Song, ZB; Tan, LP; Yang, XG; Yu, CL, 2019) |
| "Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I." | 5.39 | Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013) |
| "Psoriasis is a common dermatosis causing considerable inconvenience to 4% of the general population." | 1.51 | Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models. ( Bao, YL; Jiang, BW; Jing, QQ; Li, WJ; Li, YX; Liu, L; Liu, YC; Song, ZB; Tan, LP; Yang, XG; Yu, CL, 2019) |
| "Nitidine chloride has obvious therapeutic effects on DSS induced mouse colitis, and its anti-inflammatory mechanism is related to the down-regulation of miR-31 expression." | 1.51 | Effects of nitidine chloride on ulcerative colitis in mice and its mechanism ( Cui, XL; Liu, KL; Liu, X; Wang, CF; Wu, YL, 2019) |
| "Nitidine chloride (NC) is a benzophenanthridine alkaloid that has been reported as an antitumor agent due to its its inhibitory effects on topoisomerase I." | 1.39 | Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway. ( Cai, QY; Liao, J; Lin, JM; Peng, J; Xu, T; Yu, DB; Zheng, JX, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, XG | 1 |
| Jiang, BW | 1 |
| Jing, QQ | 1 |
| Li, WJ | 1 |
| Tan, LP | 1 |
| Bao, YL | 1 |
| Song, ZB | 1 |
| Yu, CL | 1 |
| Liu, L | 1 |
| Liu, YC | 1 |
| Li, YX | 1 |
| Wu, YL | 1 |
| Liu, X | 1 |
| Liu, KL | 1 |
| Cui, XL | 1 |
| Wang, CF | 1 |
| Yang, IH | 1 |
| Jung, W | 1 |
| Kim, LH | 1 |
| Shin, JA | 1 |
| Cho, NP | 1 |
| Hong, SD | 1 |
| Hong, KO | 1 |
| Cho, SD | 1 |
| Liao, J | 1 |
| Xu, T | 1 |
| Zheng, JX | 1 |
| Lin, JM | 1 |
| Cai, QY | 1 |
| Yu, DB | 1 |
| Peng, J | 1 |
| Liu, Q | 1 |
| Wang, T | 1 |
| Zhou, L | 1 |
| Song, F | 1 |
| Qin, A | 1 |
| Feng, HT | 1 |
| Lin, XX | 1 |
| Lin, Z | 1 |
| Yuan, JB | 1 |
| Tickner, J | 1 |
| Liu, HG | 1 |
| Zheng, MH | 1 |
| Xu, J | 1 |
| Zhao, JM | 1 |
5 other studies available for nitidine and Disease Models, Animal
| Article | Year |
|---|---|
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Topics: Animals; Apoptosis; Benzophenanthridines; Cell Line; Cell Survival; Disease Models, Animal; Female; | 2019 |
Effects of nitidine chloride on ulcerative colitis in mice and its mechanism
Topics: Animals; Benzophenanthridines; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dextran Sulfate; Diseas | 2019 |
Nitidine chloride represses Mcl-1 protein via lysosomal degradation in oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Benzophenanthridines; Carcinoma, Squamous Cell; Cell Line, Tumor; Di | 2018 |
Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridi | 2013 |
Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation.
Topics: Animals; Benzophenanthridines; Bone Resorption; Cell Differentiation; Disease Models, Animal; Dose-R | 2016 |