nitidine has been researched along with Brain Injuries in 1 studies
nitidine: RN given refers to parent cpd; synonym NSC 146397 refers to chloride; structure
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitidine was shown to prevent cultured microglia from LPS-induced reactive activation by regulation of ERK and NF-κB signaling pathway." | 1.42 | Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation. ( He, C; Hu, X; Huang, A; Pu, Y; Qin, S; Su, Z; Sun, X; Wang, D; Yuan, Y; Zhu, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, Y | 1 |
| Zhu, F | 1 |
| Pu, Y | 1 |
| Wang, D | 1 |
| Huang, A | 1 |
| Hu, X | 1 |
| Qin, S | 1 |
| Sun, X | 1 |
| Su, Z | 1 |
| He, C | 1 |
1 other study available for nitidine and Brain Injuries
| Article | Year |
|---|---|
Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation.
Topics: Animals; Benzophenanthridines; Brain Injuries; Cell Survival; Lipopolysaccharides; Macrophage Activa | 2015 |