nisoxetine has been researched along with Urinary Incontinence, Stress in 2 studies
nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.
Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the role of noradrenergic pathways in preventing stress urinary incontinence (SUI) during sneezing, we investigated the effect of the norepinephrine reuptake inhibitor nisoxetine and alpha-adrenoceptor antagonists phentolamine (nonspecific blocker) and prazosin (alpha(1)-receptor-selective blocker) on the neurally evoked urethral continence reflex induced by sneezing in rats." | 3.74 | Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats. ( Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Yoshimura, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawamorita, N | 1 |
| Kaiho, Y | 2 |
| Miyazato, M | 1 |
| Arai, Y | 2 |
| Yoshimura, N | 2 |
| Kamo, I | 1 |
| Chancellor, MB | 1 |
| de Groat, WC | 1 |
2 other studies available for nisoxetine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Roles of the spinal glutamatergic pathway activated through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Norepinephrine; Piperazines; Quinoxa | 2015 |
Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Female; Fluoxetine; Norepinephr | 2007 |