nisoxetine has been researched along with Sneezing in 2 studies
nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.
Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the role of noradrenergic pathways in preventing stress urinary incontinence (SUI) during sneezing, we investigated the effect of the norepinephrine reuptake inhibitor nisoxetine and alpha-adrenoceptor antagonists phentolamine (nonspecific blocker) and prazosin (alpha(1)-receptor-selective blocker) on the neurally evoked urethral continence reflex induced by sneezing in rats." | 3.74 | Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats. ( Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Yoshimura, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawamorita, N | 1 |
| Kaiho, Y | 2 |
| Miyazato, M | 1 |
| Arai, Y | 2 |
| Yoshimura, N | 2 |
| Kamo, I | 1 |
| Chancellor, MB | 1 |
| de Groat, WC | 1 |
2 other studies available for nisoxetine and Sneezing
| Article | Year |
|---|---|
Roles of the spinal glutamatergic pathway activated through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Norepinephrine; Piperazines; Quinoxa | 2015 |
Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Female; Fluoxetine; Norepinephr | 2007 |