nisoxetine and Pain
nisoxetine has been researched along with Pain in 3 studies
nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pain is a significant public health problem, and assessment of pain-related impairment of behavior is a key clinical indicator and treatment target." | 1.51 | Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice. ( Alexander, KS; Miller, LL; Patton, TB; Rodriguez, TR; Sarfo, AN, 2019) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Brust, A | 1 |
| Palant, E | 1 |
| Croker, DE | 1 |
| Colless, B | 1 |
| Drinkwater, R | 1 |
| Patterson, B | 1 |
| Schroeder, CI | 1 |
| Wilson, D | 1 |
| Nielsen, CK | 1 |
| Smith, MT | 1 |
| Alewood, D | 1 |
| Alewood, PF | 1 |
| Lewis, RJ | 1 |
| Alexander, KS | 1 |
| Rodriguez, TR | 1 |
| Sarfo, AN | 1 |
| Patton, TB | 1 |
| Miller, LL | 1 |
| Izenwasser, S | 1 |
| Kornetsky, C | 1 |
Other Studies
3 other studies available for nisoxetine and Pain
| Article | Year |
|---|---|
chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Chlorocebus aethiops; Conotoxins; COS Cells; Dr | 2009 |
Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bupropion; Citalopram; Conditioning, Operant; Dopamin | 2019 |
Potentiation of morphine analgesia by D-amphetamine is mediated by norepinephrine and not dopamine.
Topics: Amphetamine; Analgesics; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Electric Stimulati | 1988 |