Page last updated: 2024-11-01

nisoxetine and Pain

nisoxetine has been researched along with Pain in 3 studies

nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Pain is a significant public health problem, and assessment of pain-related impairment of behavior is a key clinical indicator and treatment target."1.51Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice. ( Alexander, KS; Miller, LL; Patton, TB; Rodriguez, TR; Sarfo, AN, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brust, A1
Palant, E1
Croker, DE1
Colless, B1
Drinkwater, R1
Patterson, B1
Schroeder, CI1
Wilson, D1
Nielsen, CK1
Smith, MT1
Alewood, D1
Alewood, PF1
Lewis, RJ1
Alexander, KS1
Rodriguez, TR1
Sarfo, AN1
Patton, TB1
Miller, LL1
Izenwasser, S1
Kornetsky, C1

Other Studies

3 other studies available for nisoxetine and Pain

ArticleYear
chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain.
    Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Chlorocebus aethiops; Conotoxins; COS Cells; Dr

2009
Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice.
    Behavioural pharmacology, 2019, Volume: 30, Issue:6

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bupropion; Citalopram; Conditioning, Operant; Dopamin

2019
Potentiation of morphine analgesia by D-amphetamine is mediated by norepinephrine and not dopamine.
    Pain, 1988, Volume: 33, Issue:3

    Topics: Amphetamine; Analgesics; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Electric Stimulati

1988