Page last updated: 2024-11-01

nisoxetine and Obesity

nisoxetine has been researched along with Obesity in 2 studies

nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Because obesity can affect catecholaminergic signaling, we determined the effects of i."1.34Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice. ( Billes, SK; Cowley, MA, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billes, SK1
Cowley, MA1
Jackson, HC1
Needham, AM1
Hutchins, LJ1
Mazurkiewicz, SE1
Heal, DJ1

Other Studies

2 other studies available for nisoxetine and Obesity

ArticleYear
Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Bupropion; Dopamine; Dose-Response Relationship, Drug; Drug

2007
Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Animals; Cyclobutanes; Cyclohexanols; Eating; Fenfluramine; Fluoxetine; Male; Neurotransmitter Uptak

1997