nisoxetine has been researched along with Muscle Contraction in 5 studies
nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nisoxetine was also less potent than desipramine in inhibiting responses to histamine, carbachol and bradykinin on the guinea-pig isolated ileum." | 1.27 | Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake. ( Foley, AJ; Leedham, JA; Pennefather, JN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizutani, H | 1 |
| Sakakibara, F | 1 |
| Sasaki, E | 1 |
| Springer, JP | 1 |
| Kropp, BP | 1 |
| Thor, KB | 1 |
| Pubill, D | 1 |
| Canudas, AM | 1 |
| Pallàs, M | 1 |
| Sureda, FX | 1 |
| Escubedo, E | 1 |
| Camins, A | 1 |
| Camarasa, J | 1 |
| Cohen, ML | 1 |
| Wiley, KS | 1 |
| Leedham, JA | 1 |
| Foley, AJ | 1 |
| Pennefather, JN | 1 |
5 other studies available for nisoxetine and Muscle Contraction
| Article | Year |
|---|---|
TAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive Bladder.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Atropine; Carbachol; Dose-Response Relationship, Dr | 2020 |
Facilitatory and inhibitory effects of selective norepinephrine reuptake inhibitors on hypogastric nerve-evoked urethral contractions in the cat: a prominent role of urethral beta-adrenergic receptors.
Topics: Animals; Atomoxetine Hydrochloride; Cats; Dose-Response Relationship, Drug; Female; Fluoxetine; Musc | 1994 |
Assessment of the adrenergic effects of orphenadrine in rat vas deferens.
Topics: Adrenergic Agents; Animals; Atropine; Binding, Competitive; Dose-Response Relationship, Drug; Drug I | 1999 |
Neuronal uptake inhibitors, nisoxetine and fluoxetine on rat vascular contractions.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Drug Interactions; Electric Stimulation; Fluoxetine; In Vit | 1977 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques | 1985 |