Page last updated: 2024-11-01

nisoxetine and Cocaine Abuse

nisoxetine has been researched along with Cocaine Abuse in 5 studies

nisoxetine: potent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain; NM refers to (+-)-isomer; RN given refers to parent cpd; structure
nisoxetine : A secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with nisoxetine and fluoxetine both attenuated cocaine-induced aversions in a manner comparable to that produced by cocaine itself."1.35Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. ( Hall, FS; Jones, JD; Rice, K; Riley, AL; Uhl, GR, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, HR1
Beveridge, TJ1
Nader, MA1
Porrino, LJ1
Jones, JD1
Hall, FS1
Uhl, GR1
Rice, K1
Riley, AL1
Mash, DC1
Ouyang, Q1
Qin, Y1
Pablo, J1
Kim, DI1
Deutsch, HM1
Ye, X1
Schweri, MM1
Platt, DM1
Rowlett, JK1
Spealman, RD1

Other Studies

5 other studies available for nisoxetine and Cocaine Abuse

ArticleYear
Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures.
    Brain structure & function, 2016, Volume: 221, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Autoradiography; Brain; Cocaine; Cocaine-Related D

2016
Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Dopamine Uptake

2009
Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers.
    Journal of neuroscience methods, 2005, Apr-15, Volume: 143, Issue:1

    Topics: Antibodies; Antibody Specificity; Binding Sites; Binding, Competitive; Brain Chemistry; Cerebral Cor

2005
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.
    Journal of medicinal chemistry, 2007, May-31, Volume: 50, Issue:11

    Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Cocaine-Related Disord

2007
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Be

2007