Page last updated: 2024-11-01

nisoldipine and Kidney Failure, Chronic

nisoldipine has been researched along with Kidney Failure, Chronic in 7 studies

Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."6.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)
"Patients with a stable progression of chronic renal failure with a creatinine clearance of 15-45 mL/min were randomly assigned to two groups of antihypertensive therapy: 1--nisoldipine as the only antihypertensive agent and 2--antihypertensive drugs without calcium channel blockers and a placebo tablet instead of nisoldipine."2.67Calcium channel blocker nisoldipine in chronic renal failure. ( Blau, A; Eliahou, HE; Herzog, D; Sachs, D; Shechter, P, 1990)
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."2.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wambach, G1
Breuer, G1
Kaufmann, W1
Blau, A1
Herzog, D4
Shechter, P3
Sachs, D1
Eliahou, HE4
Shimamatsu, K1
van Harten, J1
Burggraaf, J1
van Brummelen, P1
Breimer, DD1
Cohen, D3
Serban, I2
Kapuler, S3
Schiby, G1
Gavendo, S2
Ben-David, A2
Kogan, N2
Hellberg, B2

Trials

4 trials available for nisoldipine and Kidney Failure, Chronic

ArticleYear
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:5

    Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc

1984
Calcium channel blocker nisoldipine in chronic renal failure.
    Renal failure, 1990, Volume: 12, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Follow-Up Studies; Human

1990
The calcium channel blocker nisoldipine delays progression of chronic renal failure in humans (preliminary communication).
    Cardiovascular drugs and therapy, 1988, Volume: 1, Issue:5

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dietary Proteins; Follow-Up Studies; Humans; Hypert

1988
Effect of the calcium channel blocker nisoldipine on the progression of chronic renal failure in man.
    American journal of nephrology, 1988, Volume: 8, Issue:4

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Dietary Proteins; Energy Intake; Female; Huma

1988

Other Studies

3 other studies available for nisoldipine and Kidney Failure, Chronic

ArticleYear
Diastolic blood pressure and progression of chronic renal failure.
    Nephron, 1990, Volume: 55, Issue:4

    Topics: Diastole; Glomerulonephritis; Humans; Hypertension; Kidney Failure, Chronic; Myocardial Contraction;

1990
Influence of renal function on the pharmacokinetics and cardiovascular effects of nisoldipine after single and multiple dosing.
    Clinical pharmacokinetics, 1989, Volume: 16, Issue:1

    Topics: Administration, Oral; Adult; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule;

1989
The control of hypertension and its effect on renal function in rat remnant kidney.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1988, Volume: 3, Issue:1

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dietary Proteins; Dihydralazine; Fema

1988