nisoldipine has been researched along with Kidney Diseases in 5 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cardiovascular responses to upright tilting were determined before and after treatment with the calcium antagonist, nisoldipine, in patients with essential hypertension and in patients of similar ages and similar degrees of hypertension complicated by renal impairment." | 3.68 | Cardiovascular responses to upright tilting in hypertensive patients, with and without renal impairment and before and following nisoldipine treatment. ( Hainsworth, R; Wahbha, MM; Wilson, J, 1990) |
| " The pharmacokinetic parameters of nisoldipine and its active metabolite in the NRF and IRF groups did not differ after the single and the consecutive dosing." | 2.68 | Pharmacokinetics and pharmacodynamics of nisoldipine in hypertensive patients with normal and mild to moderate impaired renal function. ( Jinno, Y; Masumori, S; Minamisawa, K; Minamisawa, M; Nagasawa, T; Satta, H; Shionoiri, H; Takasaki, I; Takeda, K; Takizawa, T, 1995) |
| "Nisoldipine is a high-clearance drug with substantial interindividual and relatively lower intraindividual variability in pharmacokinetics, dependent on liver blood flow." | 2.40 | Clinical pharmacokinetics of nisoldipine coat-core. ( Heinig, R, 1998) |
| " No significant differences were observed between Groups A, B and C (on an interdialysis day) in AUC (0-7h), tmax, Cmax and plasma protein binding." | 1.27 | Pharmacokinetics of nisoldipine in renal dysfunction. ( Ahr, G; Boelaert, J; Bogaert, MG; Dammekens, H; Daneels, R; De Vriese, G; Schurgers, M; Valcke, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shionoiri, H | 1 |
| Minamisawa, K | 1 |
| Masumori, S | 1 |
| Satta, H | 1 |
| Minamisawa, M | 1 |
| Takizawa, T | 1 |
| Jinno, Y | 1 |
| Takeda, K | 1 |
| Nagasawa, T | 1 |
| Takasaki, I | 1 |
| Heinig, R | 1 |
| Wahbha, MM | 1 |
| Wilson, J | 2 |
| Hainsworth, R | 1 |
| Orchard, MA | 1 |
| Spencer, AA | 1 |
| Davies, JA | 1 |
| Prentice, CR | 1 |
| Boelaert, J | 1 |
| Valcke, Y | 1 |
| Dammekens, H | 1 |
| De Vriese, G | 1 |
| Ahr, G | 1 |
| Schurgers, M | 1 |
| Daneels, R | 1 |
| Bogaert, MG | 1 |
1 review available for nisoldipine and Kidney Diseases
| Article | Year |
|---|---|
Clinical pharmacokinetics of nisoldipine coat-core.
Topics: Age Factors; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug In | 1998 |
2 trials available for nisoldipine and Kidney Diseases
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of nisoldipine in hypertensive patients with normal and mild to moderate impaired renal function.
Topics: Blood Pressure; Female; Half-Life; Heart Rate; Humans; Hypertension; Kidney Diseases; Male; Middle A | 1995 |
Anti-hypertensive drugs non-specifically reduce "spontaneous" activation of blood platelets.
Topics: Adult; Aged; Antihypertensive Agents; beta-Thromboglobulin; Double-Blind Method; Drug Evaluation; Fe | 1989 |
2 other studies available for nisoldipine and Kidney Diseases
| Article | Year |
|---|---|
Cardiovascular responses to upright tilting in hypertensive patients, with and without renal impairment and before and following nisoldipine treatment.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Kidne | 1990 |
Pharmacokinetics of nisoldipine in renal dysfunction.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Kidney Diseases; | 1988 |