nisoldipine has been researched along with Hypertension, Renal in 8 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nisoldipine was well tolerated and an effective antihypertensive agent when administered over a period of 6 weeks." | 6.66 | The effect of nisoldipine on renal function in the long-term treatment of hypertension in patients with and without renal impairment. ( Brownjohn, AM; Davies, JA; Hainsworth, R; Martin, PG; Prentice, CR; Turney, JH; Wahbha, MM; Wilson, J, 1989) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 6.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| "Patients with a stable progression of chronic renal failure with a creatinine clearance of 15-45 mL/min were randomly assigned to two groups of antihypertensive therapy: 1--nisoldipine as the only antihypertensive agent and 2--antihypertensive drugs without calcium channel blockers and a placebo tablet instead of nisoldipine." | 2.67 | Calcium channel blocker nisoldipine in chronic renal failure. ( Blau, A; Eliahou, HE; Herzog, D; Sachs, D; Shechter, P, 1990) |
| "Nisoldipine was well tolerated and an effective antihypertensive agent when administered over a period of 6 weeks." | 2.66 | The effect of nisoldipine on renal function in the long-term treatment of hypertension in patients with and without renal impairment. ( Brownjohn, AM; Davies, JA; Hainsworth, R; Martin, PG; Prentice, CR; Turney, JH; Wahbha, MM; Wilson, J, 1989) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 2.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| "3-3 mg/kg), dose-response curves of the antihypertensive effect did not change and body weight gain was equal to that of the vehicle-treated group." | 1.28 | Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs. ( Haruno, A; Kanda, A; Miyake, H; Nagasaka, M, 1992) |
| " Nisoldipine had the lowest maximum plasma concentration and the longest elimination half-life among the four 1,4-dihydropyridines, resulting in no significant difference in the area under the plasma concentration-time curve." | 1.27 | Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs. ( Kato, H; Takata, Y, 1986) |
| "Nisoldipine has a long lasting antihypertensive action (12 hr at 0." | 1.26 | Nisoldipine (BAY K 5552), a new calcium antagonist. Antihypertensive effect in conscious, unrestrained renal hypertensive dogs. ( Knorr, A, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wambach, G | 1 |
| Breuer, G | 1 |
| Kaufmann, W | 1 |
| Knorr, A | 1 |
| Kanda, A | 1 |
| Haruno, A | 1 |
| Miyake, H | 1 |
| Nagasaka, M | 1 |
| Liu, WH | 1 |
| Fu, SX | 1 |
| Li, YS | 1 |
| Blau, A | 1 |
| Herzog, D | 1 |
| Shechter, P | 1 |
| Sachs, D | 1 |
| Eliahou, HE | 1 |
| Wilson, J | 1 |
| Wahbha, MM | 1 |
| Martin, PG | 1 |
| Hainsworth, R | 1 |
| Brownjohn, AM | 1 |
| Turney, JH | 1 |
| Davies, JA | 1 |
| Prentice, CR | 1 |
| Tasaka, K | 1 |
| Kamei, C | 1 |
| Tagami, H | 1 |
| Hokonohara, T | 1 |
| Sugimoto, Y | 1 |
| Takata, Y | 1 |
| Kato, H | 1 |
3 trials available for nisoldipine and Hypertension, Renal
| Article | Year |
|---|---|
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc | 1984 |
Calcium channel blocker nisoldipine in chronic renal failure.
Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Follow-Up Studies; Human | 1990 |
The effect of nisoldipine on renal function in the long-term treatment of hypertension in patients with and without renal impairment.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method | 1989 |
5 other studies available for nisoldipine and Hypertension, Renal
| Article | Year |
|---|---|
Nisoldipine (BAY K 5552), a new calcium antagonist. Antihypertensive effect in conscious, unrestrained renal hypertensive dogs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Heart Rate | 1982 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Co | 1992 |
Antihypertensive effects of m-nisoldipine and nisoldipine on conscious renal hypertensive rats and dogs.
Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension, R | 1992 |
Antihypertensive effects of nisoldipine and reference drugs in certain types of hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension, | 1987 |
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relation | 1986 |