Page last updated: 2024-11-01

nisoldipine and Coronary Disease

nisoldipine has been researched along with Coronary Disease in 64 studies

Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0."6.67[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993)
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them."6.67[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990)
"The purpose of this study was to determine the response of plasma levels of endothelin-1 (ET-1) to dynamic exercise in patients with coronary artery disease and chronic stable angina pectoris and positive exercise tolerance test, before and after treatment with the calcium antagonist nisoldipine (20 mg/day buccally for 7 days)."3.69Plasma endothelin-1 concentrations in patients with coronary artery disease during stress test before and after nisoldipine administration. ( Barillà, F; Campa, PP; Cerci, S; Coassin, S; D'Ambrosio, C; De Ciocchis, A; Letizia, C; Mastroianni, MA; Scavo, D, 1996)
" Among 15 patients with coronary artery disease who had been treated with nisoldipine, onset of severe unstable angina was observed in 2 and evolution of acute myocardial infarction in 1 patient after abrupt withdrawal of nisoldipine therapy."3.67Calcium-blocker withdrawal phenomenon: increase in affinity of alpha 2 adrenoceptors for agonist as a potential mechanism. ( Lopez, LM; Mehta, J, 1986)
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0."2.67[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993)
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them."2.67[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990)
"Nisoldipine is a new calcium channel blocker of the dihydropyridine family with a high affinity for coronary vessels."2.66Silent myocardial ischemia: improvement with nisoldipine therapy. ( Arce-Weston, B; Clark, PI; Glasser, SP, 1989)
" After a stable control period, dose-response curves were constructed for each drug with hemodynamics measured 10 minutes after intravenous boluses."2.66Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. ( Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP, 1987)
"Nisoldipine is a newly developed calcium channel blocker with outstanding vasodilatory properties especially with regard to the coronary arteries."2.66The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy. ( Flint, GR; Herbst, CP; Otto, AC; Sweetlove, MA; van Aswegen, A; Viviers, AC, 1988)
" The required equally effective dosage was 0."2.66[Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function]. ( Aschenberg, W; Bleifeld, W; Nienaber, C; Spielmann, R, 1988)
"Nisoldipine proved to be a potent calcium antagonist with slower onset and longer duration of action than nifedipine."2.66A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function. ( Herbst, CP; Otto, AC; Strugo, V; Sweetlove, A; van Aswegen, A, 1987)
"Nisoldipine was found to improve both left ventricular systolic and diastolic function without activating the adrenergic system."2.39Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease. ( Marini, A; Sheiban, I; Tonni, S; Trevi, G, 1995)
"Nisoldipine is a second-generation dihydropyridine calcium antagonist structurally related to nifedipine and used in the treatment of stable angina and arterial hypertension."2.39Clinical pharmacology of nisoldipine coat core. ( Zannad, F, 1995)
"Treatment with nisoldipine induces a beneficial effect by reduction of infarct size in repeated coronary reperfusion."1.30Beneficial effect of nisoldipine in repeated coronary reperfusion. ( Hammerman, H; Hir, J; Moscovitz, M, 1997)
"Pretreatment with nisoldipine completely prevented these increases."1.28Nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium. ( Gordon-Majszak, W; Herbaczynska-Cedro, K, 1990)
" In order to compare the pharmacokinetic properties of these compounds the dilation of the 'normal' coronary segments was correlated with the respective drug plasma levels; maximal plasma concentrations averaged 62 +/- 21 ng ml-1 (7th min) in group I and 17 +/- 7 ng ml-1 (4th min) in group II respectively."1.28Coronary vasodilation with dihydropyridines--a pharmacokinetic study. ( Bossaller, C; Hecker, H; Jost, S; Lichtlen, PR; Lippolt, P; Mogwitz, B; Nellessen, U; Rafflenbeul, W; Zwicky, P, 1989)
"When nisoldipine was included 10 min before ischemia, during ischemia (33 min) and reperfusion (30 min), however, the recovery of cardiac function and tissue ATP levels was significantly increased."1.27A low concentration of nisoldipine reduces ischemic heart injury: enhanced reflow and recovery of contractile function without energy preservation during ischemia. ( Hatley, AA; Watts, JA; Whipple, JP, 1987)
" In 10 patients resting cardiac stroke output (thermodilution) and pulmonary artery occluded pressure were determined following four intravenous nisoldipine injections (cumulative dosage of 1, 2, 4 and 8 micrograms kg-1)."1.27Haemodynamic dose-response effects of intravenous nisoldipine in coronary artery disease. ( Frais, MA; Muller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1985)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199028 (43.75)18.7374
1990's34 (53.13)18.2507
2000's2 (3.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dens, J1
Desmet, W1
Piessens, J1
Takahashi, K2
Kako, KJ2
Klein, HH1
Schwarck, H1
Rauschning, W1
Kreuzer, H1
Altura, BM1
Altura, BT1
Brügmann, U1
Blasini, R1
Rudolph, W2
De Jong, JW1
Huizer, T1
Tijssen, JG1
Warltier, DC1
Meils, CM1
Gross, GJ1
Brooks, HL1
Fagbemi, O1
Parratt, JR1
Leischik, R1
Adamczewski, O1
Pötter, S1
Erbel, R1
Lösse, B1
Heintz, B1
vom Dahl, J1
Roeber, K1
Doettger, A1
Hanrath, P1
Sieberth, HG1
Sheiban, I2
Tonni, S2
Marini, A2
Trevi, G1
Brunelli, C1
Parodi, O1
Sambuceti, G1
Corsiglia, L1
Rosa, GM1
Giorgetti, A1
Bezante, GP1
Nista, N1
Caponnetto, S1
Zannad, F1
Fehske, W1
Niedeggen, A1
Omran, H1
Pizzulli, L1
Manz, M1
Lüderitz, B1
Grönefeld, G1
Bernhardt, J1
Schneider, W1
Benussi, P1
Trevi, GP1
Mauser, M2
Voelker, W2
Ickrath, O2
Karsch, KR2
Jost, S4
Sturm, M1
Hausmann, D1
Lippolt, P2
Lichtlen, PR4
Letizia, C1
Barillà, F1
Cerci, S1
De Ciocchis, A1
Coassin, S1
Mastroianni, MA1
D'Ambrosio, C1
Campa, PP1
Scavo, D1
Fujinishi, A1
Takahara, K1
Ohba, C1
Nakashima, Y1
Kuroiwa, A1
Hammerman, H1
Moscovitz, M1
Hir, J1
Nolte, CW1
Mügge, A1
Daniel, WG1
Dens, JA1
Desmet, WJ1
Coussement, P1
De Scheerder, IK1
Kostopoulos, K1
Kerdsinchai, P1
Supanantaroek, C1
Piessens, JH1
Tartagni, F2
Melandri, G2
De Tommaso, I1
Fallani, F1
di Niro, M1
Antonioli, P1
Dondi, M2
Corbelli, C1
Magnani, B2
Eber, B1
Schumacher, M1
Zweiker, R1
Pokan, R1
Klein, W1
Watts, JA4
Chapat, S1
Johnson, DE1
Janis, RA1
Amende, I2
Bentivegna, LA1
Zeind, AJ1
Wenzlaff, P2
Grossman, W1
Morgan, JP1
Crottogini, AJ1
Lascano, EC1
Barra, JG1
Morales, MC1
Depaoli, JR1
Pichel, RH1
Hawes, EM1
Jenkins, SH1
Williams, TC1
Fox, K1
Pool, J1
Vos, J1
Lubsen, J1
Tilton, RG1
Land, MP1
Larson, KB1
Sutera, SP1
Williamson, JR1
Scognamiglio, R1
Ponchia, A1
Fasoli, G1
Miraglia, G1
Dalla-Volta, S1
Waters, D1
Lehmann, G1
Reiniger, G1
Wolf, H1
Beyerle, A1
Tzivoni, D2
Banai, S2
Botvin, S1
Zilberman, A1
Weiss, TA1
Gavish, A1
Medina, A1
Benhorin, J2
Rogel, S1
Caspi, A1
Salmasi, AM1
Salmasi, S1
MacDonald, G1
Nicolaides, AN1
Sievert, H1
Friedmann, A1
Schräder, R1
Winkelmann, B1
Kaltenbach, M1
Kober, G1
Kühlkamp, V1
Kurita, A1
Takase, B2
Uehata, A1
Sugawara, H1
Nishioka, T1
Maruyama, T1
Satomura, K1
Kondo, S1
Mizuno, K1
Isojima, K1
Herbaczynska-Cedro, K1
Gordon-Majszak, W1
Rafflenbeul, W2
Mogwitz, B2
Gulba, D1
Hecker, H2
Kimball, BP1
Watson, KR1
Bui, S1
Frankel, D1
Herrmann, G1
Simon, R1
Nellessen, U1
Bossaller, C1
Zwicky, P1
Glasser, SP1
Arce-Weston, B1
Clark, PI1
Stern, S1
Silke, B3
Frais, MA3
Midtbo, KA2
Verma, SP3
Sharma, S1
Reynolds, G3
Jackson, N1
Taylor, SH3
Mehta, J1
Lopez, LM1
Otto, AC2
van Aswegen, A2
Herbst, CP2
Sweetlove, MA1
Viviers, AC1
Flint, GR1
McDonagh, PF1
Roberts, DJ1
Aschenberg, W1
Nienaber, C1
Spielmann, R1
Bleifeld, W1
Sweetlove, A1
Strugo, V1
Mentley, RK1
Brezinski, ME1
Tse, E1
Lefer, AM1
Dymond, DS1
Caplin, JL1
O'Keefe, JC1
Banim, S1
Whipple, JP1
Hatley, AA1
Kling, D1
Boldt, J1
Moosdorf, R1
von Bormann, B1
Hempelmann, G1
Müller, P2
Rùggiero, S1
Beato, E1
Monetti, N1
Suryapranata, H1
Serruys, PW1
Soward, AL1
Planellas, J1
Vanhaleweyk, G1
Hugenholtz, PG1
Lam, J1
Chaitman, BR1
Crean, P1
Blum, R1
Waters, DD1
Kimchi, A1
Ellrodt, AG1
Charuzi, Y1
Shell, W1
Murata, GH1

Reviews

5 reviews available for nisoldipine and Coronary Disease

ArticleYear
An updated meta-analysis of calcium-channel blockers in the prevention of restenosis after coronary angioplasty.
    American heart journal, 2003, Volume: 145, Issue:3

    Topics: Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Confidence Intervals; Coronary

2003
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
    Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:2

    Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe

1984
Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease.
    The American journal of cardiology, 1995, Apr-27, Volume: 75, Issue:13

    Topics: Chronic Disease; Coronary Circulation; Coronary Disease; Humans; Myocardial Contraction; Myocardial

1995
Clinical pharmacology of nisoldipine coat core.
    The American journal of cardiology, 1995, Apr-27, Volume: 75, Issue:13

    Topics: Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Hemodynamics; Humans; Myocardia

1995
[Nisoldipine in comparison with long-term nitrates].
    Acta medica Austriaca, 1992, Volume: 19, Issue:5

    Topics: Angina Pectoris; Animals; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Humans; Myocar

1992

Trials

24 trials available for nisoldipine and Coronary Disease

ArticleYear
[Comparison of the anti-ischemia effect of nisoldipine and verapamil. Double-blind randomized cross-over and placebo-controlled acute and long-term study].
    Herz, 1984, Volume: 9, Issue:4

    Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Diseas

1984
[Stress echocardiography--a new test for evaluating the anti-ischemic effect of medication].
    Zeitschrift fur Kardiologie, 1995, Volume: 84, Issue:8

    Topics: Aged; Coronary Disease; Cross-Over Studies; Double-Blind Method; Echocardiography; Electrocardiograp

1995
Effects of blood pressure reduction on the elastic profile of the aortic tree in patients with coronary heart disease.
    American journal of hypertension, 1995, Volume: 8, Issue:6

    Topics: Adult; Aorta; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Coronary Disease; Elasticity; Hemod

1995
Perfusional and metabolic effects of nisoldipine as shown by positron emission tomography after acute myocardial infarction.
    The American journal of cardiology, 1995, Apr-27, Volume: 75, Issue:13

    Topics: Adult; Coronary Circulation; Coronary Disease; Dobutamine; Echocardiography; Heart; Humans; Myocardi

1995
[Effect of nisoldipine and diltiazem on systolic and diastolic function of the left ventricle in patients with coronary heart disease].
    Zeitschrift fur Kardiologie, 1994, Volume: 83, Issue:1

    Topics: Aged; Coronary Disease; Diastole; Diltiazem; Echocardiography, Doppler; Exercise Test; Female; Hemod

1994
[Dose-response relationship of nisoldipine in patients with stable angina pectoris and stress-induced myocardial ischemia].
    Zeitschrift fur Kardiologie, 1993, Volume: 82, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Cardiac Catheterization; Coronary Disease; Delayed-Action Preparations

1993
Left ventricular dysfunction following transient ischaemia induced by transluminal coronary angioplasty. Beneficial effects of calcium antagonists against post-ischaemic myocardial stunning.
    European heart journal, 1993, Volume: 14 Suppl A

    Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Circulation; Coronary Disease

1993
[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease].
    Zeitschrift fur Kardiologie, 1993, Volume: 82, Issue:1

    Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Exercise Test; Felodip

1993
Usefulness of Nisoldipine for prevention of restenosis after percutaneous transluminal coronary angioplasty (results of the NICOLE study). NIsoldipine in COronary artery disease in LEuven.
    The American journal of cardiology, 2001, Jan-01, Volume: 87, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; De

2001
The effects of nisoldipine on the total ischaemic burden: the results of the ROCKET study.
    European heart journal, 1991, Volume: 12, Issue:12

    Topics: Coronary Disease; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory

1991
[Effectiveness of various combination therapies in patients with coronary heart disease].
    Herz, 1990, Volume: 15, Issue:6

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-Blind Met

1990
Effects of nisoldipine on myocardial ischemia during exercise and during daily activity.
    The American journal of cardiology, 1991, Mar-15, Volume: 67, Issue:7

    Topics: Activities of Daily Living; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electr

1991
Improvement of silent myocardial ischaemia and reduction of plasma fibrinogen during nisoldipine therapy in occult coronary arterial disease.
    International journal of cardiology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Coronary Disease; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test;

1991
[Effect of the calcium antagonist nisoldipine on coronary circulation and myocardial ischemia in temporary coronary occlusion].
    Zeitschrift fur Kardiologie, 1990, Volume: 79, Issue:10

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Combined Modality Therapy; Coronary Circulation; Corona

1990
[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease].
    Deutsche medizinische Wochenschrift (1946), 1990, May-11, Volume: 115, Issue:19

    Topics: Blood Pressure; Calcium Channel Blockers; Coronary Disease; Heart; Heart Rate; Humans; Infusions, In

1990
Silent myocardial ischemia: improvement with nisoldipine therapy.
    Southern medical journal, 1989, Volume: 82, Issue:1

    Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electroca

1989
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Re

1987
The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy.
    European journal of nuclear medicine, 1988, Volume: 14, Issue:11

    Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Meth

1988
[Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function].
    Zeitschrift fur Kardiologie, 1988, Volume: 77, Issue:4

    Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Catheterization; Clinical Trials as Topic; Coronary D

1988
A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function.
    European journal of nuclear medicine, 1987, Volume: 13, Issue:2

    Topics: Aged; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Female; Hemodynamics; Humans;

1987
[Hemodynamic effects of nisoldipine (Bay k 5552), a calcium antagonist, in coronary surgery patients].
    Der Anaesthesist, 1986, Volume: 35, Issue:10

    Topics: Calcium Channel Blockers; Coronary Disease; Coronary Vasospasm; Extracorporeal Circulation; Hemodyna

1986
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease.
    International journal of cardiology, 1986, Volume: 13, Issue:2

    Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemod

1986
Acute coronary hemodynamic effects of equihypotensive doses of nisoldipine and diltiazem.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:6

    Topics: Adult; Aged; Benzazepines; Blood Flow Velocity; Calcium Channel Blockers; Coronary Disease; Coronary

1985
A dose-ranging, placebo-controlled, double-blind trial of nisoldipine in effort angina: duration and extent of antianginal effects.
    Journal of the American College of Cardiology, 1985, Volume: 6, Issue:2

    Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Dose-Re

1985

Other Studies

35 other studies available for nisoldipine and Coronary Disease

ArticleYear
Ischemia-induced changes in sarcolemmal (Na+, K+)-ATPase, K+-pNPPase, sialic acid, and phospholipid in the dog and effects of the nisoldipine and chlorpromazine treatment.
    Biochemical medicine, 1984, Volume: 31, Issue:3

    Topics: 4-Nitrophenylphosphatase; Animals; Chlorpromazine; Coronary Disease; Dogs; Electrocardiography; Fema

1984
Effect of nisoldipine on electrophysiological parameters in patients pretreated with beta-blockers.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Catheterization; Coronary Disease; Elect

1984
Energy conservation by nisoldipine in ischaemic heart.
    British journal of pharmacology, 1984, Volume: 83, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Coronary Circulation; Coronary D

1984
Blood flow in normal and acutely ischemic myocardium after verapamil, diltiazem and nisoldipine (Bay k 5552), a new dihydropyridine calcium antagonist.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1

    Topics: Animals; Benzazepines; Calcium; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Hem

1981
Suppression by orally-administered nifedipine, nisoldipine and niludipine of early, life-threatening ventricular arrhythmias resulting from acute myocardial ischaemia.
    British journal of pharmacology, 1981, Volume: 74, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; H

1981
Standardization of coronary vasomotor tone with intracoronary nitroglycerin.
    The American journal of cardiology, 1996, Jul-01, Volume: 78, Issue:1

    Topics: Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Coronary Angiography; Coronary Disea

1996
Plasma endothelin-1 concentrations in patients with coronary artery disease during stress test before and after nisoldipine administration.
    Acta cardiologica, 1996, Volume: 51, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Endothelins; Exercise Test

1996
Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease.
    Angiology, 1997, Volume: 48, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Antithrombin III; beta-Thromboglobulin; Blood Coagulation; Blood

1997
Beneficial effect of nisoldipine in repeated coronary reperfusion.
    Coronary artery disease, 1997, Volume: 8, Issue:2

    Topics: Animals; Calcium Channel Blockers; Coronary Disease; Disease Models, Animal; Dogs; Hemodynamics; Inf

1997
Protection from digoxin-induced coronary vasoconstriction in patients with coronary artery disease by calcium antagonists.
    The American journal of cardiology, 1999, Feb-01, Volume: 83, Issue:3

    Topics: Acetyldigoxins; Calcium Channel Blockers; Cardiotonic Agents; Coronary Angiography; Coronary Disease

1999
Effects of nisoldipine in coronary artery disease: a radioisotopic approach.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 5

    Topics: Administration, Oral; Blood Pressure; Coronary Disease; Electrocardiography; Heart; Humans; Male; Mi

1992
Effects of nisoldipine upon vasoconstrictor responses and binding of endothelin-1 in ischemic and reperfused rat hearts.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Coronary

1992
Intracellular calcium and ventricular function. Effects of nisoldipine on global ischemia in the isovolumic, coronary-perfused heart.
    The Journal of clinical investigation, 1992, Volume: 89, Issue:6

    Topics: Animals; Calcium; Coronary Disease; Ferrets; Heart Ventricles; Hemodynamics; In Vitro Techniques; Ma

1992
Effect of long-term oral nisoldipine on infarct size and collateral development in pigs undergoing gradual occlusion of the left circumflex artery.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:4

    Topics: Administration, Oral; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Endocardium;

1990
Effects of nisoldipine on the no-reflow phenomenon in globally ischemic rat hearts.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:3

    Topics: Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Energy Metabolism; In Vitro T

1990
Discordant effects of nisoldipine on coronary vascular resistance and permeability changes during reflow after ischemia in isolated rabbit hearts.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:7

    Topics: Animals; Blood Flow Velocity; Cardiac Volume; Coronary Circulation; Coronary Disease; Endothelium, V

1991
Exercise-induced left ventricular dysfunction in coronary heart disease. A model for studying the stunned myocardium in man.
    European heart journal, 1991, Volume: 12 Suppl G

    Topics: Adult; Coronary Disease; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Nisoldipine;

1991
Proischemic complications of dihydropyridine calcium channel blockers.
    Circulation, 1991, Volume: 84, Issue:6

    Topics: Angina Pectoris; Coronary Disease; Coronary Vessels; Humans; Nisoldipine

1991
Effects of a low, oral dose of nisoldipine on the systemic and coronary hemodynamics and the prostaglandin metabolism of ischemic heart disease patients.
    Japanese heart journal, 1990, Volume: 31, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Aged; Blood Pressure; Coronary Circulatio

1990
Nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium.
    Cardiovascular research, 1990, Volume: 24, Issue:8

    Topics: Acute Disease; Animals; Coronary Disease; Hemodynamics; Lipid Peroxidation; Myocardium; Nisoldipine;

1990
Vasodilatory effects of nisoldipine on coronary arteries--correlation with plasma levels.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:1

    Topics: Adult; Aorta; Blood Pressure; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Hear

1990
[Responses of plasma eicosanoids and hemodynamics to myocardial ischemia and the salutary effect of calcium entry blocker].
    Nihon Ika Daigaku zasshi, 1990, Volume: 57, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Coronary Circulation; Coronary Disease; Eicosanoids; Exercise Test; He

1990
Preservation of left ventricular performance with reduced ischemic dysfunction by intravenous nisoldipine.
    The American journal of cardiology, 1990, Aug-15, Volume: 66, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Heart; Humans; Infusions, Intravenous; Injec

1990
Intracoronary nisoldipine: effects on acute myocardial ischemia during coronary angioplasty.
    Cardiovascular drugs and therapy, 1989, Volume: 2, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Vessels; Female; Humans; Injections, Intr

1989
Coronary vasodilation with dihydropyridines--a pharmacokinetic study.
    European heart journal, 1989, Volume: 10 Suppl F

    Topics: Adult; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Hemodynamics; Humans; Male;

1989
Effect of nisoldipine on myocardial ischemia during daily activities: a preliminary report.
    Israel journal of medical sciences, 1989, Volume: 25, Issue:9

    Topics: Activities of Daily Living; Aged; Coronary Disease; Electrocardiography, Ambulatory; Female; Humans;

1989
Calcium-blocker withdrawal phenomenon: increase in affinity of alpha 2 adrenoceptors for agonist as a potential mechanism.
    The American journal of cardiology, 1986, Aug-01, Volume: 58, Issue:3

    Topics: Adult; Angina Pectoris; Blood Platelets; Calcium Channel Blockers; Coronary Disease; Epinephrine; Hu

1986
Prevention of transcoronary macromolecular leakage after ischemia-reperfusion by the calcium entry blocker nisoldipine. Direct observations in isolated rat hearts.
    Circulation research, 1986, Volume: 58, Issue:1

    Topics: Animals; Capillaries; Coronary Circulation; Coronary Disease; Coronary Vessels; Extravasation of Dia

1986
Cardioprotective actions of nisoldipine in postreperfusion myocardial ischemia.
    American heart journal, 1988, Volume: 115, Issue:5

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cats; Coronary Circulation; Coronary Disease; Cre

1988
Effects of nisoldipine on left ventricular function during exercise or cold pressor stress.
    European heart journal, 1987, Volume: 8 Suppl K

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cold Temperature; Coronary Disease; Exercise Test;

1987
A low concentration of nisoldipine reduces ischemic heart injury: enhanced reflow and recovery of contractile function without energy preservation during ischemia.
    Journal of molecular and cellular cardiology, 1987, Volume: 19, Issue:8

    Topics: Adenosine Triphosphate; Animals; Cardiac Output; Coronary Circulation; Coronary Disease; Energy Meta

1987
The effects of myocardial ischemia and nisoldipine pretreatment on the asymmetric distribution of phosphatidylethanolamine in a canine heart sarcolemmal preparation.
    Biochemical medicine and metabolic biology, 1986, Volume: 35, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cell Fractionation; Chlorpromazine; Coronary Disease; Dogs; Femal

1986
Effects of oral nisoldipine in ischemic heart disease. A radioisotopic study.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Administration, Oral; Cardiovascular System; Coronary Disease; Evaluation Studies as Topic; Exercise

1986
Salutary hemodynamic and sustained clinical beneficial effects of nisoldipine, a new calcium channel blocker, in patients with recurrent ischemia and severe heart failure.
    American heart journal, 1985, Volume: 110, Issue:2

    Topics: Aged; Calcium Channel Blockers; Coronary Disease; Heart Failure; Hemodynamics; Humans; Male; Mitral

1985
Haemodynamic dose-response effects of intravenous nisoldipine in coronary artery disease.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:6

    Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Dose-Response Relationship,

1985