nisoldipine has been researched along with Coronary Disease in 64 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Excerpt | Relevance | Reference |
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"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 6.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them." | 6.67 | [Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990) |
"The purpose of this study was to determine the response of plasma levels of endothelin-1 (ET-1) to dynamic exercise in patients with coronary artery disease and chronic stable angina pectoris and positive exercise tolerance test, before and after treatment with the calcium antagonist nisoldipine (20 mg/day buccally for 7 days)." | 3.69 | Plasma endothelin-1 concentrations in patients with coronary artery disease during stress test before and after nisoldipine administration. ( Barillà, F; Campa, PP; Cerci, S; Coassin, S; D'Ambrosio, C; De Ciocchis, A; Letizia, C; Mastroianni, MA; Scavo, D, 1996) |
" Among 15 patients with coronary artery disease who had been treated with nisoldipine, onset of severe unstable angina was observed in 2 and evolution of acute myocardial infarction in 1 patient after abrupt withdrawal of nisoldipine therapy." | 3.67 | Calcium-blocker withdrawal phenomenon: increase in affinity of alpha 2 adrenoceptors for agonist as a potential mechanism. ( Lopez, LM; Mehta, J, 1986) |
"To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 2.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
" In this dosage peripheral effects--decrease of peripheral vascular resistance and mean aortic pressure--did not differ significantly between them." | 2.67 | [Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease]. ( Ickrath, O; Karsch, KR; Kühlkamp, V; Mauser, M; Voelker, W, 1990) |
"Nisoldipine is a new calcium channel blocker of the dihydropyridine family with a high affinity for coronary vessels." | 2.66 | Silent myocardial ischemia: improvement with nisoldipine therapy. ( Arce-Weston, B; Clark, PI; Glasser, SP, 1989) |
" After a stable control period, dose-response curves were constructed for each drug with hemodynamics measured 10 minutes after intravenous boluses." | 2.66 | Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease. ( Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP, 1987) |
"Nisoldipine is a newly developed calcium channel blocker with outstanding vasodilatory properties especially with regard to the coronary arteries." | 2.66 | The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy. ( Flint, GR; Herbst, CP; Otto, AC; Sweetlove, MA; van Aswegen, A; Viviers, AC, 1988) |
" The required equally effective dosage was 0." | 2.66 | [Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function]. ( Aschenberg, W; Bleifeld, W; Nienaber, C; Spielmann, R, 1988) |
"Nisoldipine proved to be a potent calcium antagonist with slower onset and longer duration of action than nifedipine." | 2.66 | A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function. ( Herbst, CP; Otto, AC; Strugo, V; Sweetlove, A; van Aswegen, A, 1987) |
"Nisoldipine was found to improve both left ventricular systolic and diastolic function without activating the adrenergic system." | 2.39 | Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease. ( Marini, A; Sheiban, I; Tonni, S; Trevi, G, 1995) |
"Nisoldipine is a second-generation dihydropyridine calcium antagonist structurally related to nifedipine and used in the treatment of stable angina and arterial hypertension." | 2.39 | Clinical pharmacology of nisoldipine coat core. ( Zannad, F, 1995) |
"Treatment with nisoldipine induces a beneficial effect by reduction of infarct size in repeated coronary reperfusion." | 1.30 | Beneficial effect of nisoldipine in repeated coronary reperfusion. ( Hammerman, H; Hir, J; Moscovitz, M, 1997) |
"Pretreatment with nisoldipine completely prevented these increases." | 1.28 | Nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium. ( Gordon-Majszak, W; Herbaczynska-Cedro, K, 1990) |
" In order to compare the pharmacokinetic properties of these compounds the dilation of the 'normal' coronary segments was correlated with the respective drug plasma levels; maximal plasma concentrations averaged 62 +/- 21 ng ml-1 (7th min) in group I and 17 +/- 7 ng ml-1 (4th min) in group II respectively." | 1.28 | Coronary vasodilation with dihydropyridines--a pharmacokinetic study. ( Bossaller, C; Hecker, H; Jost, S; Lichtlen, PR; Lippolt, P; Mogwitz, B; Nellessen, U; Rafflenbeul, W; Zwicky, P, 1989) |
"When nisoldipine was included 10 min before ischemia, during ischemia (33 min) and reperfusion (30 min), however, the recovery of cardiac function and tissue ATP levels was significantly increased." | 1.27 | A low concentration of nisoldipine reduces ischemic heart injury: enhanced reflow and recovery of contractile function without energy preservation during ischemia. ( Hatley, AA; Watts, JA; Whipple, JP, 1987) |
" In 10 patients resting cardiac stroke output (thermodilution) and pulmonary artery occluded pressure were determined following four intravenous nisoldipine injections (cumulative dosage of 1, 2, 4 and 8 micrograms kg-1)." | 1.27 | Haemodynamic dose-response effects of intravenous nisoldipine in coronary artery disease. ( Frais, MA; Muller, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (43.75) | 18.7374 |
1990's | 34 (53.13) | 18.2507 |
2000's | 2 (3.13) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dens, J | 1 |
Desmet, W | 1 |
Piessens, J | 1 |
Takahashi, K | 2 |
Kako, KJ | 2 |
Klein, HH | 1 |
Schwarck, H | 1 |
Rauschning, W | 1 |
Kreuzer, H | 1 |
Altura, BM | 1 |
Altura, BT | 1 |
Brügmann, U | 1 |
Blasini, R | 1 |
Rudolph, W | 2 |
De Jong, JW | 1 |
Huizer, T | 1 |
Tijssen, JG | 1 |
Warltier, DC | 1 |
Meils, CM | 1 |
Gross, GJ | 1 |
Brooks, HL | 1 |
Fagbemi, O | 1 |
Parratt, JR | 1 |
Leischik, R | 1 |
Adamczewski, O | 1 |
Pötter, S | 1 |
Erbel, R | 1 |
Lösse, B | 1 |
Heintz, B | 1 |
vom Dahl, J | 1 |
Roeber, K | 1 |
Doettger, A | 1 |
Hanrath, P | 1 |
Sieberth, HG | 1 |
Sheiban, I | 2 |
Tonni, S | 2 |
Marini, A | 2 |
Trevi, G | 1 |
Brunelli, C | 1 |
Parodi, O | 1 |
Sambuceti, G | 1 |
Corsiglia, L | 1 |
Rosa, GM | 1 |
Giorgetti, A | 1 |
Bezante, GP | 1 |
Nista, N | 1 |
Caponnetto, S | 1 |
Zannad, F | 1 |
Fehske, W | 1 |
Niedeggen, A | 1 |
Omran, H | 1 |
Pizzulli, L | 1 |
Manz, M | 1 |
Lüderitz, B | 1 |
Grönefeld, G | 1 |
Bernhardt, J | 1 |
Schneider, W | 1 |
Benussi, P | 1 |
Trevi, GP | 1 |
Mauser, M | 2 |
Voelker, W | 2 |
Ickrath, O | 2 |
Karsch, KR | 2 |
Jost, S | 4 |
Sturm, M | 1 |
Hausmann, D | 1 |
Lippolt, P | 2 |
Lichtlen, PR | 4 |
Letizia, C | 1 |
Barillà, F | 1 |
Cerci, S | 1 |
De Ciocchis, A | 1 |
Coassin, S | 1 |
Mastroianni, MA | 1 |
D'Ambrosio, C | 1 |
Campa, PP | 1 |
Scavo, D | 1 |
Fujinishi, A | 1 |
Takahara, K | 1 |
Ohba, C | 1 |
Nakashima, Y | 1 |
Kuroiwa, A | 1 |
Hammerman, H | 1 |
Moscovitz, M | 1 |
Hir, J | 1 |
Nolte, CW | 1 |
Mügge, A | 1 |
Daniel, WG | 1 |
Dens, JA | 1 |
Desmet, WJ | 1 |
Coussement, P | 1 |
De Scheerder, IK | 1 |
Kostopoulos, K | 1 |
Kerdsinchai, P | 1 |
Supanantaroek, C | 1 |
Piessens, JH | 1 |
Tartagni, F | 2 |
Melandri, G | 2 |
De Tommaso, I | 1 |
Fallani, F | 1 |
di Niro, M | 1 |
Antonioli, P | 1 |
Dondi, M | 2 |
Corbelli, C | 1 |
Magnani, B | 2 |
Eber, B | 1 |
Schumacher, M | 1 |
Zweiker, R | 1 |
Pokan, R | 1 |
Klein, W | 1 |
Watts, JA | 4 |
Chapat, S | 1 |
Johnson, DE | 1 |
Janis, RA | 1 |
Amende, I | 2 |
Bentivegna, LA | 1 |
Zeind, AJ | 1 |
Wenzlaff, P | 2 |
Grossman, W | 1 |
Morgan, JP | 1 |
Crottogini, AJ | 1 |
Lascano, EC | 1 |
Barra, JG | 1 |
Morales, MC | 1 |
Depaoli, JR | 1 |
Pichel, RH | 1 |
Hawes, EM | 1 |
Jenkins, SH | 1 |
Williams, TC | 1 |
Fox, K | 1 |
Pool, J | 1 |
Vos, J | 1 |
Lubsen, J | 1 |
Tilton, RG | 1 |
Land, MP | 1 |
Larson, KB | 1 |
Sutera, SP | 1 |
Williamson, JR | 1 |
Scognamiglio, R | 1 |
Ponchia, A | 1 |
Fasoli, G | 1 |
Miraglia, G | 1 |
Dalla-Volta, S | 1 |
Waters, D | 1 |
Lehmann, G | 1 |
Reiniger, G | 1 |
Wolf, H | 1 |
Beyerle, A | 1 |
Tzivoni, D | 2 |
Banai, S | 2 |
Botvin, S | 1 |
Zilberman, A | 1 |
Weiss, TA | 1 |
Gavish, A | 1 |
Medina, A | 1 |
Benhorin, J | 2 |
Rogel, S | 1 |
Caspi, A | 1 |
Salmasi, AM | 1 |
Salmasi, S | 1 |
MacDonald, G | 1 |
Nicolaides, AN | 1 |
Sievert, H | 1 |
Friedmann, A | 1 |
Schräder, R | 1 |
Winkelmann, B | 1 |
Kaltenbach, M | 1 |
Kober, G | 1 |
Kühlkamp, V | 1 |
Kurita, A | 1 |
Takase, B | 2 |
Uehata, A | 1 |
Sugawara, H | 1 |
Nishioka, T | 1 |
Maruyama, T | 1 |
Satomura, K | 1 |
Kondo, S | 1 |
Mizuno, K | 1 |
Isojima, K | 1 |
Herbaczynska-Cedro, K | 1 |
Gordon-Majszak, W | 1 |
Rafflenbeul, W | 2 |
Mogwitz, B | 2 |
Gulba, D | 1 |
Hecker, H | 2 |
Kimball, BP | 1 |
Watson, KR | 1 |
Bui, S | 1 |
Frankel, D | 1 |
Herrmann, G | 1 |
Simon, R | 1 |
Nellessen, U | 1 |
Bossaller, C | 1 |
Zwicky, P | 1 |
Glasser, SP | 1 |
Arce-Weston, B | 1 |
Clark, PI | 1 |
Stern, S | 1 |
Silke, B | 3 |
Frais, MA | 3 |
Midtbo, KA | 2 |
Verma, SP | 3 |
Sharma, S | 1 |
Reynolds, G | 3 |
Jackson, N | 1 |
Taylor, SH | 3 |
Mehta, J | 1 |
Lopez, LM | 1 |
Otto, AC | 2 |
van Aswegen, A | 2 |
Herbst, CP | 2 |
Sweetlove, MA | 1 |
Viviers, AC | 1 |
Flint, GR | 1 |
McDonagh, PF | 1 |
Roberts, DJ | 1 |
Aschenberg, W | 1 |
Nienaber, C | 1 |
Spielmann, R | 1 |
Bleifeld, W | 1 |
Sweetlove, A | 1 |
Strugo, V | 1 |
Mentley, RK | 1 |
Brezinski, ME | 1 |
Tse, E | 1 |
Lefer, AM | 1 |
Dymond, DS | 1 |
Caplin, JL | 1 |
O'Keefe, JC | 1 |
Banim, S | 1 |
Whipple, JP | 1 |
Hatley, AA | 1 |
Kling, D | 1 |
Boldt, J | 1 |
Moosdorf, R | 1 |
von Bormann, B | 1 |
Hempelmann, G | 1 |
Müller, P | 2 |
Rùggiero, S | 1 |
Beato, E | 1 |
Monetti, N | 1 |
Suryapranata, H | 1 |
Serruys, PW | 1 |
Soward, AL | 1 |
Planellas, J | 1 |
Vanhaleweyk, G | 1 |
Hugenholtz, PG | 1 |
Lam, J | 1 |
Chaitman, BR | 1 |
Crean, P | 1 |
Blum, R | 1 |
Waters, DD | 1 |
Kimchi, A | 1 |
Ellrodt, AG | 1 |
Charuzi, Y | 1 |
Shell, W | 1 |
Murata, GH | 1 |
5 reviews available for nisoldipine and Coronary Disease
Article | Year |
---|---|
An updated meta-analysis of calcium-channel blockers in the prevention of restenosis after coronary angioplasty.
Topics: Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Confidence Intervals; Coronary | 2003 |
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease.
Topics: Chronic Disease; Coronary Circulation; Coronary Disease; Humans; Myocardial Contraction; Myocardial | 1995 |
Clinical pharmacology of nisoldipine coat core.
Topics: Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Hemodynamics; Humans; Myocardia | 1995 |
[Nisoldipine in comparison with long-term nitrates].
Topics: Angina Pectoris; Animals; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Humans; Myocar | 1992 |
24 trials available for nisoldipine and Coronary Disease
Article | Year |
---|---|
[Comparison of the anti-ischemia effect of nisoldipine and verapamil. Double-blind randomized cross-over and placebo-controlled acute and long-term study].
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Diseas | 1984 |
[Stress echocardiography--a new test for evaluating the anti-ischemic effect of medication].
Topics: Aged; Coronary Disease; Cross-Over Studies; Double-Blind Method; Echocardiography; Electrocardiograp | 1995 |
Effects of blood pressure reduction on the elastic profile of the aortic tree in patients with coronary heart disease.
Topics: Adult; Aorta; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Coronary Disease; Elasticity; Hemod | 1995 |
Perfusional and metabolic effects of nisoldipine as shown by positron emission tomography after acute myocardial infarction.
Topics: Adult; Coronary Circulation; Coronary Disease; Dobutamine; Echocardiography; Heart; Humans; Myocardi | 1995 |
[Effect of nisoldipine and diltiazem on systolic and diastolic function of the left ventricle in patients with coronary heart disease].
Topics: Aged; Coronary Disease; Diastole; Diltiazem; Echocardiography, Doppler; Exercise Test; Female; Hemod | 1994 |
[Dose-response relationship of nisoldipine in patients with stable angina pectoris and stress-induced myocardial ischemia].
Topics: Adult; Aged; Angina Pectoris; Cardiac Catheterization; Coronary Disease; Delayed-Action Preparations | 1993 |
Left ventricular dysfunction following transient ischaemia induced by transluminal coronary angioplasty. Beneficial effects of calcium antagonists against post-ischaemic myocardial stunning.
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Circulation; Coronary Disease | 1993 |
[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease].
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Exercise Test; Felodip | 1993 |
Usefulness of Nisoldipine for prevention of restenosis after percutaneous transluminal coronary angioplasty (results of the NICOLE study). NIsoldipine in COronary artery disease in LEuven.
Topics: Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; De | 2001 |
The effects of nisoldipine on the total ischaemic burden: the results of the ROCKET study.
Topics: Coronary Disease; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory | 1991 |
[Effectiveness of various combination therapies in patients with coronary heart disease].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-Blind Met | 1990 |
Effects of nisoldipine on myocardial ischemia during exercise and during daily activity.
Topics: Activities of Daily Living; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electr | 1991 |
Improvement of silent myocardial ischaemia and reduction of plasma fibrinogen during nisoldipine therapy in occult coronary arterial disease.
Topics: Adult; Aged; Coronary Disease; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; | 1991 |
[Effect of the calcium antagonist nisoldipine on coronary circulation and myocardial ischemia in temporary coronary occlusion].
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Combined Modality Therapy; Coronary Circulation; Corona | 1990 |
[Myocardial effects of the calcium antagonists nifedipine, nisoldipine and isradipine in coronary heart disease].
Topics: Blood Pressure; Calcium Channel Blockers; Coronary Disease; Heart; Heart Rate; Humans; Infusions, In | 1990 |
Silent myocardial ischemia: improvement with nisoldipine therapy.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electroca | 1989 |
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Re | 1987 |
The effects of nisoldipine on left ventricular filling rate in patients with ischemic heart disease measured with radionuclide gated blood pool scintigraphy.
Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind Meth | 1988 |
[Comparison of the acute hemodynamic effect of nisoldipine (Bay k 5552) and nifedipine in patients with ischemia-induced left ventricular impaired function].
Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Catheterization; Clinical Trials as Topic; Coronary D | 1988 |
A comparison of the acute hemodynamic effects of nifedipine and nisoldipine in patients with ischemic reduced left ventricular function.
Topics: Aged; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Female; Hemodynamics; Humans; | 1987 |
[Hemodynamic effects of nisoldipine (Bay k 5552), a calcium antagonist, in coronary surgery patients].
Topics: Calcium Channel Blockers; Coronary Disease; Coronary Vasospasm; Extracorporeal Circulation; Hemodyna | 1986 |
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemod | 1986 |
Acute coronary hemodynamic effects of equihypotensive doses of nisoldipine and diltiazem.
Topics: Adult; Aged; Benzazepines; Blood Flow Velocity; Calcium Channel Blockers; Coronary Disease; Coronary | 1985 |
A dose-ranging, placebo-controlled, double-blind trial of nisoldipine in effort angina: duration and extent of antianginal effects.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Dose-Re | 1985 |
35 other studies available for nisoldipine and Coronary Disease
Article | Year |
---|---|
Ischemia-induced changes in sarcolemmal (Na+, K+)-ATPase, K+-pNPPase, sialic acid, and phospholipid in the dog and effects of the nisoldipine and chlorpromazine treatment.
Topics: 4-Nitrophenylphosphatase; Animals; Chlorpromazine; Coronary Disease; Dogs; Electrocardiography; Fema | 1984 |
Effect of nisoldipine on electrophysiological parameters in patients pretreated with beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Catheterization; Coronary Disease; Elect | 1984 |
Energy conservation by nisoldipine in ischaemic heart.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Coronary Circulation; Coronary D | 1984 |
Blood flow in normal and acutely ischemic myocardium after verapamil, diltiazem and nisoldipine (Bay k 5552), a new dihydropyridine calcium antagonist.
Topics: Animals; Benzazepines; Calcium; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Hem | 1981 |
Suppression by orally-administered nifedipine, nisoldipine and niludipine of early, life-threatening ventricular arrhythmias resulting from acute myocardial ischaemia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; H | 1981 |
Standardization of coronary vasomotor tone with intracoronary nitroglycerin.
Topics: Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Coronary Angiography; Coronary Disea | 1996 |
Plasma endothelin-1 concentrations in patients with coronary artery disease during stress test before and after nisoldipine administration.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Endothelins; Exercise Test | 1996 |
Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Antithrombin III; beta-Thromboglobulin; Blood Coagulation; Blood | 1997 |
Beneficial effect of nisoldipine in repeated coronary reperfusion.
Topics: Animals; Calcium Channel Blockers; Coronary Disease; Disease Models, Animal; Dogs; Hemodynamics; Inf | 1997 |
Protection from digoxin-induced coronary vasoconstriction in patients with coronary artery disease by calcium antagonists.
Topics: Acetyldigoxins; Calcium Channel Blockers; Cardiotonic Agents; Coronary Angiography; Coronary Disease | 1999 |
Effects of nisoldipine in coronary artery disease: a radioisotopic approach.
Topics: Administration, Oral; Blood Pressure; Coronary Disease; Electrocardiography; Heart; Humans; Male; Mi | 1992 |
Effects of nisoldipine upon vasoconstrictor responses and binding of endothelin-1 in ischemic and reperfused rat hearts.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Coronary | 1992 |
Intracellular calcium and ventricular function. Effects of nisoldipine on global ischemia in the isovolumic, coronary-perfused heart.
Topics: Animals; Calcium; Coronary Disease; Ferrets; Heart Ventricles; Hemodynamics; In Vitro Techniques; Ma | 1992 |
Effect of long-term oral nisoldipine on infarct size and collateral development in pigs undergoing gradual occlusion of the left circumflex artery.
Topics: Administration, Oral; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Endocardium; | 1990 |
Effects of nisoldipine on the no-reflow phenomenon in globally ischemic rat hearts.
Topics: Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Energy Metabolism; In Vitro T | 1990 |
Discordant effects of nisoldipine on coronary vascular resistance and permeability changes during reflow after ischemia in isolated rabbit hearts.
Topics: Animals; Blood Flow Velocity; Cardiac Volume; Coronary Circulation; Coronary Disease; Endothelium, V | 1991 |
Exercise-induced left ventricular dysfunction in coronary heart disease. A model for studying the stunned myocardium in man.
Topics: Adult; Coronary Disease; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Nisoldipine; | 1991 |
Proischemic complications of dihydropyridine calcium channel blockers.
Topics: Angina Pectoris; Coronary Disease; Coronary Vessels; Humans; Nisoldipine | 1991 |
Effects of a low, oral dose of nisoldipine on the systemic and coronary hemodynamics and the prostaglandin metabolism of ischemic heart disease patients.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Aged; Blood Pressure; Coronary Circulatio | 1990 |
Nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium.
Topics: Acute Disease; Animals; Coronary Disease; Hemodynamics; Lipid Peroxidation; Myocardium; Nisoldipine; | 1990 |
Vasodilatory effects of nisoldipine on coronary arteries--correlation with plasma levels.
Topics: Adult; Aorta; Blood Pressure; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Hear | 1990 |
[Responses of plasma eicosanoids and hemodynamics to myocardial ischemia and the salutary effect of calcium entry blocker].
Topics: 6-Ketoprostaglandin F1 alpha; Coronary Circulation; Coronary Disease; Eicosanoids; Exercise Test; He | 1990 |
Preservation of left ventricular performance with reduced ischemic dysfunction by intravenous nisoldipine.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Heart; Humans; Infusions, Intravenous; Injec | 1990 |
Intracoronary nisoldipine: effects on acute myocardial ischemia during coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Vessels; Female; Humans; Injections, Intr | 1989 |
Coronary vasodilation with dihydropyridines--a pharmacokinetic study.
Topics: Adult; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Hemodynamics; Humans; Male; | 1989 |
Effect of nisoldipine on myocardial ischemia during daily activities: a preliminary report.
Topics: Activities of Daily Living; Aged; Coronary Disease; Electrocardiography, Ambulatory; Female; Humans; | 1989 |
Calcium-blocker withdrawal phenomenon: increase in affinity of alpha 2 adrenoceptors for agonist as a potential mechanism.
Topics: Adult; Angina Pectoris; Blood Platelets; Calcium Channel Blockers; Coronary Disease; Epinephrine; Hu | 1986 |
Prevention of transcoronary macromolecular leakage after ischemia-reperfusion by the calcium entry blocker nisoldipine. Direct observations in isolated rat hearts.
Topics: Animals; Capillaries; Coronary Circulation; Coronary Disease; Coronary Vessels; Extravasation of Dia | 1986 |
Cardioprotective actions of nisoldipine in postreperfusion myocardial ischemia.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cats; Coronary Circulation; Coronary Disease; Cre | 1988 |
Effects of nisoldipine on left ventricular function during exercise or cold pressor stress.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cold Temperature; Coronary Disease; Exercise Test; | 1987 |
A low concentration of nisoldipine reduces ischemic heart injury: enhanced reflow and recovery of contractile function without energy preservation during ischemia.
Topics: Adenosine Triphosphate; Animals; Cardiac Output; Coronary Circulation; Coronary Disease; Energy Meta | 1987 |
The effects of myocardial ischemia and nisoldipine pretreatment on the asymmetric distribution of phosphatidylethanolamine in a canine heart sarcolemmal preparation.
Topics: Animals; Calcium Channel Blockers; Cell Fractionation; Chlorpromazine; Coronary Disease; Dogs; Femal | 1986 |
Effects of oral nisoldipine in ischemic heart disease. A radioisotopic study.
Topics: Administration, Oral; Cardiovascular System; Coronary Disease; Evaluation Studies as Topic; Exercise | 1986 |
Salutary hemodynamic and sustained clinical beneficial effects of nisoldipine, a new calcium channel blocker, in patients with recurrent ischemia and severe heart failure.
Topics: Aged; Calcium Channel Blockers; Coronary Disease; Heart Failure; Hemodynamics; Humans; Male; Mitral | 1985 |
Haemodynamic dose-response effects of intravenous nisoldipine in coronary artery disease.
Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Dose-Response Relationship, | 1985 |