nisoldipine has been researched along with Cirrhosis, Liver in 3 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compared with previously published data from young healthy volunteers, the values for Cmax and AUC appear to be higher in elderly hypertensive patients while Tmax and half-life were unchanged." | 2.68 | The effect of age and liver disease on the pharmacokinetics of the calcium antagonist, nisoldipine. ( Davidson, C; Davidsson, GK; Edwards, JS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davidsson, GK | 1 |
| Edwards, JS | 1 |
| Davidson, C | 1 |
| Heinig, R | 1 |
| Muschalek, V | 1 |
| Ahr, G | 1 |
| van Harten, J | 1 |
| van Brummelen, P | 1 |
| Wilson, JH | 1 |
| Lodewijks, MT | 1 |
| Breimer, DD | 1 |
1 trial available for nisoldipine and Cirrhosis, Liver
| Article | Year |
|---|---|
The effect of age and liver disease on the pharmacokinetics of the calcium antagonist, nisoldipine.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Calcium Channel Blockers; Edema; | 1995 |
2 other studies available for nisoldipine and Cirrhosis, Liver
| Article | Year |
|---|---|
Determination of the enantiomers of nisoldipine in human plasma using high-performance liquid chromatography on a chiral stationary phase and gas chromatography with mass-selective detection.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Deuterium; Female; Humans; Hypertension; Liver Ci | 1994 |
Nisoldipine: kinetics and effects on blood pressure and heart rate in patients with liver cirrhosis after intravenous and oral administration.
Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Hal | 1988 |