nisoldipine has been researched along with Chronic Illness in 9 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute and chronic effects of the dihydropyridine calcium antagonist nisoldipine were studied in patients with chronic heart failure (LV EF < ." | 9.07 | Acute and chronic effects of the dihydropyridine calcium antagonist nisoldipine on the resting and exercise hemodynamics, neurohumoral parameters, and functional capacity of patients with chronic heart failure. ( Dei Cas, L; Ferrari, R; Metra, M; Visioli, O, 1993) |
| "We studied the acute effects of the calcium antagonist nisoldipine in 10 conscious pigs with chronic heart failure." | 7.68 | Nisoldipine improves blood flow to skeletal muscles in conscious pigs with chronic heart failure. ( Roelandt, JR; Saxena, PR; van der Giessen, WJ; van Woerkens, LJ; Verdouw, PD, 1990) |
| "The acute systemic hemodynamic effects of the calcium antagonist nisoldipine and the pyridazinone-derivative pimobendan, a phosphodiesterase inhibitor with vasodilating as well as positive inotropic properties, were studied in conscious pigs with chronic heart failure." | 7.67 | Acute hemodynamic effects of nisoldipine and pimobendan in conscious pigs with chronic heart failure. ( Duncker, DJ; Roelandt, JR; van der Giessen, WJ; van Woerkens, LJ; Verdouw, PD, 1989) |
| " This trial confirms that immediate-release nisoldipine when added to existent beta-blocker therapy is an active antianginal and anti-ischemic agent, but that the immediate-release formulation loses its antianginal effect at the end of its dosing interval (9 to 14 hours)." | 6.67 | Antianginal and anti-ischemic efficacy of immediate-release nisoldipine in chronic stable angina pectoris. ( Bittar, N; Glasser, SP; Katz, R; Labreche, DG; Schulman, P; Singh, B, 1994) |
| "Nisoldipine is a second-generation dihydropyridine calcium antagonist that has been extensively studied as an antianginal and antihypertensive agent." | 6.39 | Nisoldipine coat core as concomitant therapy in chronic stable angina pectoris. ( Glasser, SP, 1995) |
| "The acute and chronic effects of the dihydropyridine calcium antagonist nisoldipine were studied in patients with chronic heart failure (LV EF < ." | 5.07 | Acute and chronic effects of the dihydropyridine calcium antagonist nisoldipine on the resting and exercise hemodynamics, neurohumoral parameters, and functional capacity of patients with chronic heart failure. ( Dei Cas, L; Ferrari, R; Metra, M; Visioli, O, 1993) |
| "We studied the acute effects of the calcium antagonist nisoldipine in 10 conscious pigs with chronic heart failure." | 3.68 | Nisoldipine improves blood flow to skeletal muscles in conscious pigs with chronic heart failure. ( Roelandt, JR; Saxena, PR; van der Giessen, WJ; van Woerkens, LJ; Verdouw, PD, 1990) |
| "The acute systemic hemodynamic effects of the calcium antagonist nisoldipine and the pyridazinone-derivative pimobendan, a phosphodiesterase inhibitor with vasodilating as well as positive inotropic properties, were studied in conscious pigs with chronic heart failure." | 3.67 | Acute hemodynamic effects of nisoldipine and pimobendan in conscious pigs with chronic heart failure. ( Duncker, DJ; Roelandt, JR; van der Giessen, WJ; van Woerkens, LJ; Verdouw, PD, 1989) |
| " This trial confirms that immediate-release nisoldipine when added to existent beta-blocker therapy is an active antianginal and anti-ischemic agent, but that the immediate-release formulation loses its antianginal effect at the end of its dosing interval (9 to 14 hours)." | 2.67 | Antianginal and anti-ischemic efficacy of immediate-release nisoldipine in chronic stable angina pectoris. ( Bittar, N; Glasser, SP; Katz, R; Labreche, DG; Schulman, P; Singh, B, 1994) |
| "A double-blind, placebo-controlled study was performed to assess whether a new calcium antagonist, nisoldipine, in doses of either 5 mg or 10 mg daily, in combination with beta-adrenergic-blocking drugs (combination therapy) was more effective than beta-adrenergic-blocking drugs alone (single therapy) in the treatment of chronic stable angina." | 2.66 | Efficacy of nisoldipine combined with beta-adrenergic-blocking drugs in the treatment of chronic stable angina. ( Banim, SO; Creamer, JE; O'Keefe, JC, 1987) |
| "Nisoldipine is an effective antianginal agent which performs well in comparison to nifedipine." | 2.66 | Comparative antianginal effects of nisoldipine and nifedipine in patients with chronic stable angina. ( Chaitman, BR; Crean, PA; Lam, J; Waters, DD, 1987) |
| "Nisoldipine was found to improve both left ventricular systolic and diastolic function without activating the adrenergic system." | 2.39 | Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease. ( Marini, A; Sheiban, I; Tonni, S; Trevi, G, 1995) |
| "Nisoldipine is a second-generation dihydropyridine calcium antagonist that has been extensively studied as an antianginal and antihypertensive agent." | 2.39 | Nisoldipine coat core as concomitant therapy in chronic stable angina pectoris. ( Glasser, SP, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheiban, I | 1 |
| Tonni, S | 1 |
| Marini, A | 1 |
| Trevi, G | 1 |
| Glasser, SP | 3 |
| Bittar, N | 2 |
| Labreche, DG | 1 |
| Singh, B | 1 |
| Katz, R | 1 |
| Schulman, P | 1 |
| Dei Cas, L | 1 |
| Metra, M | 1 |
| Ferrari, R | 1 |
| Visioli, O | 1 |
| Ripa, S | 1 |
| Garland, WT | 1 |
| Weiss, R | 1 |
| Nademanee, K | 1 |
| Singh, S | 1 |
| van der Giessen, WJ | 2 |
| van Woerkens, LJ | 2 |
| Saxena, PR | 1 |
| Roelandt, JR | 2 |
| Verdouw, PD | 2 |
| Duncker, DJ | 1 |
| O'Keefe, JC | 1 |
| Creamer, JE | 1 |
| Banim, SO | 1 |
| Crean, PA | 1 |
| Waters, DD | 1 |
| Lam, J | 1 |
| Chaitman, BR | 1 |
2 reviews available for nisoldipine and Chronic Illness
| Article | Year |
|---|---|
Clinical and therapeutic implications of chronic left ventricular dysfunction in coronary artery disease.
Topics: Chronic Disease; Coronary Circulation; Coronary Disease; Humans; Myocardial Contraction; Myocardial | 1995 |
Nisoldipine coat core as concomitant therapy in chronic stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Chronic Disease; Delayed-Action Preparations; Drug The | 1995 |
5 trials available for nisoldipine and Chronic Illness
| Article | Year |
|---|---|
Antianginal and anti-ischemic efficacy of immediate-release nisoldipine in chronic stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Chronic Disease; Double-Blind M | 1994 |
Acute and chronic effects of the dihydropyridine calcium antagonist nisoldipine on the resting and exercise hemodynamics, neurohumoral parameters, and functional capacity of patients with chronic heart failure.
Topics: Adult; Aged; Chronic Disease; Exercise; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Ag | 1993 |
Antianginal and antiischemic efficacy of monotherapy extended-release nisoldipine (Coat Core) in chronic stable angina.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Delayed- | 1995 |
Efficacy of nisoldipine combined with beta-adrenergic-blocking drugs in the treatment of chronic stable angina.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Chronic Disease; Coronary Angiography; Double-Bl | 1987 |
Comparative antianginal effects of nisoldipine and nifedipine in patients with chronic stable angina.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Double-B | 1987 |
2 other studies available for nisoldipine and Chronic Illness
| Article | Year |
|---|---|
Nisoldipine improves blood flow to skeletal muscles in conscious pigs with chronic heart failure.
Topics: Adrenal Glands; Animals; Cardiac Output; Chronic Disease; Coronary Circulation; Heart Failure; Hemod | 1990 |
Acute hemodynamic effects of nisoldipine and pimobendan in conscious pigs with chronic heart failure.
Topics: Acid-Base Equilibrium; Animals; Blood Gas Analysis; Chronic Disease; Heart Failure; Hemodynamics; Ni | 1989 |