nisoldipine has been researched along with Cardiomegaly in 3 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age." | 7.67 | Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987) |
| "This study examined the protective effects of a calcium channel blocker, nisoldipine (NSL), against organ damage secondary to severe hypertension." | 3.69 | Benefits and demerits of antihypertensive therapy by high-dose calcium channel blocker in severely hypertensive rats. ( Ishimitsu, T; Ogawa, Y; Tsukada, H; Yagi, S, 1994) |
| "The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age." | 3.67 | Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogawa, Y | 1 |
| Ishimitsu, T | 1 |
| Tsukada, H | 1 |
| Yagi, S | 1 |
| Stasch, JP | 2 |
| Kazda, S | 2 |
| Hirth-Dietrich, C | 1 |
| Neuser, D | 1 |
| Hirth, C | 1 |
| Morich, F | 1 |
3 other studies available for nisoldipine and Cardiomegaly
| Article | Year |
|---|---|
Benefits and demerits of antihypertensive therapy by high-dose calcium channel blocker in severely hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Body Weight; Calcium Channel Blockers; Cardiomegaly; Dose-R | 1994 |
Effects of nisoldipine on atrial natriuretic peptides, blood pressure and cardiac hypertrophy in Dahl rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Male; Minoxidil; Nisoldipine; Rats | 1990 |
Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Hypertension; Male; Nifedipine; Ni | 1987 |