nisoldipine has been researched along with Autoimmune Diabetes in 6 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to compare the effect of a long-acting calcium antagonist (nisoldipine) versus an ACE inhibitor (lisinopril) on albuminuria, arterial blood pressure, and glomerular filtration rate (GFR) in hypertensive IDDM patients with diabetic nephropathy." | 9.08 | Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment. ( Boelskifte, S; Jensen, BR; Nielsen, FS; Parving, HH; Rossing, P; Tarnow, L, 1997) |
| "73 m](-2); mean 24-h ambulatory blood pressure was 108 +/- 3 and 105 +/- 2 mmHg, and albuminuria was 1,554 mg/24 h (95% CI 980-2,465) and 1,033 mg/24 h (760-1,406) in the lisinopril and nisoldipine groups, respectively." | 5.09 | Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy. ( Hansen, BV; Jensen, C; Parving, HH; Rossing, P; Tarnow, L, 2000) |
| "Our objective was to compare the effect of a long-acting calcium antagonist (nisoldipine) versus an ACE inhibitor (lisinopril) on albuminuria, arterial blood pressure, and glomerular filtration rate (GFR) in hypertensive IDDM patients with diabetic nephropathy." | 5.08 | Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment. ( Boelskifte, S; Jensen, BR; Nielsen, FS; Parving, HH; Rossing, P; Tarnow, L, 1997) |
| "Nisoldipine treatment for seven days is not associated with altered platelet function, but platelet hypersensitivity is observed after treatment for 24 hours in both insulin-dependent diabetics and controls." | 1.27 | Ex vivo platelet studies following oral nisoldipine in normotensive insulin-dependent diabetics and non-diabetic controls. ( Betteridge, DJ; Dandona, P; Hendra, TJ; Jeremy, JY; Oughton, J; Smith, CC; Yudkin, JS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rossing, P | 4 |
| Tarnow, L | 4 |
| Boelskifte, S | 1 |
| Jensen, BR | 1 |
| Nielsen, FS | 2 |
| Parving, HH | 3 |
| Sørensen, VB | 1 |
| Parving, H | 1 |
| Nørgaard, T | 1 |
| Kastrup, J | 1 |
| Sato, A | 1 |
| Ali, S | 1 |
| Cooper, ME | 1 |
| Jensen, C | 1 |
| Hansen, BV | 1 |
| Hendra, TJ | 1 |
| Oughton, J | 1 |
| Jeremy, JY | 1 |
| Smith, CC | 1 |
| Betteridge, DJ | 1 |
| Dandona, P | 1 |
| Yudkin, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00311870] | Phase 4 | 52 participants | Interventional | 1993-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for nisoldipine and Autoimmune Diabetes
| Article | Year |
|---|---|
Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur | 1997 |
Effects of nisoldipine and lisinopril on microvascular dysfunction in hypertensive Type I diabetes patients with nephropathy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Delayed-A | 1998 |
Effects of nisoldipine and lisinopril on left ventricular mass and function in diabetic nephropathy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulato | 1999 |
Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur | 2000 |
2 other studies available for nisoldipine and Autoimmune Diabetes
| Article | Year |
|---|---|
Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy: response to Tarnow et al.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabete | 2000 |
Ex vivo platelet studies following oral nisoldipine in normotensive insulin-dependent diabetics and non-diabetic controls.
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Platelets; Catecholamines; Collagen; Diabetes Mel | 1988 |