nisoldipine has been researched along with Arrhythmias, Cardiac in 10 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "m-Nisoldipine iv 3, 5 and 10 micrograms/kg before coronary artery ligation markedly reduced the early ischemic arrhythmia in conscious rats." | 7.67 | [Effects of m-nisoldipine on ischemic arrhythmia in conscious rats]. ( An, RH; Fu, SX; Li, YS, 1989) |
| "They prevented reperfusion arrhythmias exacerbated by X-XOD and decreased the free radicals generated by X-XOD." | 5.28 | Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat. ( Fu, SX; Li, YL; Li, YS, 1989) |
| " We therefore decided to compare the influence of oral and intravenous administration of furnidipine, nifedipine, nitrendipine and nimodipine to examine their effects on hemodynamics and arrhythmias." | 3.78 | Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine. ( Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B, 2012) |
| "m-Nisoldipine iv 3, 5 and 10 micrograms/kg before coronary artery ligation markedly reduced the early ischemic arrhythmia in conscious rats." | 3.67 | [Effects of m-nisoldipine on ischemic arrhythmia in conscious rats]. ( An, RH; Fu, SX; Li, YS, 1989) |
| "The intravenous administration of either nifedipine (in doses of 5-50 microgram/kg), or nisoldipine (5-1000 microgram/kg) markedly reduced, or abolished, the serious ventricular arrhythmias (tachycardia and fibrillation) that result from acute coronary artery artery ligation in pentobarbitone-anaesthetized rats." | 3.66 | Calcium antagonists prevent early post-infarction ventricular fibrillation. ( Fagbemi, O; Parratt, JR, 1981) |
| "They prevented reperfusion arrhythmias exacerbated by X-XOD and decreased the free radicals generated by X-XOD." | 1.28 | Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat. ( Fu, SX; Li, YL; Li, YS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Splawski, I | 1 |
| Timothy, KW | 1 |
| Sharpe, LM | 1 |
| Decher, N | 1 |
| Kumar, P | 1 |
| Bloise, R | 1 |
| Napolitano, C | 1 |
| Schwartz, PJ | 1 |
| Joseph, RM | 1 |
| Condouris, K | 1 |
| Tager-Flusberg, H | 1 |
| Priori, SG | 1 |
| Sanguinetti, MC | 1 |
| Keating, MT | 1 |
| Mitręga, KA | 1 |
| Varghese, B | 1 |
| Porc, M | 1 |
| Krzemiński, TF | 1 |
| Fagbemi, O | 2 |
| Parratt, JR | 2 |
| Bjørnstad, H | 1 |
| Lathrop, DA | 1 |
| Refsum, H | 1 |
| Li, YL | 2 |
| Fu, SX | 3 |
| Li, YS | 3 |
| An, RH | 1 |
| Thandroyen, FT | 1 |
| Flint, NS | 1 |
| Worthington, MG | 1 |
| Opie, LH | 1 |
| Vatner, SF | 1 |
| Patrick, TA | 1 |
| Knight, DR | 1 |
| Manders, WT | 1 |
| Fallon, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives[NCT04832126] | 100 participants (Anticipated) | Observational | 2018-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for nisoldipine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Topics: Abnormalities, Multiple; Action Potentials; Animals; Arrhythmias, Cardiac; Autistic Disorder; Brain; | 2004 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Car | 2012 |
Suppression by orally-administered nifedipine, nisoldipine and niludipine of early, life-threatening ventricular arrhythmias resulting from acute myocardial ischaemia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; H | 1981 |
Calcium antagonists prevent early post-infarction ventricular fibrillation.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Hemodynamics; Male; Myocardial Infarction; | 1981 |
Prevention of some hypothermia induced electromechanical changes by calcium channel blockade.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cold Temperatur | 1994 |
Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat.
Topics: Animals; Arrhythmias, Cardiac; Free Radicals; Male; Myocardial Reperfusion Injury; Nisoldipine; Rats | 1989 |
[Effects of m-nisoldipine on ischemic arrhythmia in conscious rats].
Topics: Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; | 1989 |
Arrhythmogenic action of alpha 1-adrenoceptor stimulation in normoxic rat ventricular myocardium: influence of nisoldipine, reduced extracellular Ca2+ and ryanodine.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Arrhythmias, Cardiac; Azepines; Calcium; Calcium Chan | 1987 |
[Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmia in hearts of rats].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Fatty Acids, Nonesterified; Free Radicals; Isomerism; Male; | 1988 |
Effects of calcium channel blocker on responses of blood flow, function, arrhythmias, and extent of infarction following reperfusion in conscious baboons.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Cre | 1988 |