nisoldipine has been researched along with Arrhythmia in 10 studies
Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.
| Excerpt | Relevance | Reference |
|---|---|---|
| "m-Nisoldipine iv 3, 5 and 10 micrograms/kg before coronary artery ligation markedly reduced the early ischemic arrhythmia in conscious rats." | 7.67 | [Effects of m-nisoldipine on ischemic arrhythmia in conscious rats]. ( An, RH; Fu, SX; Li, YS, 1989) |
| "They prevented reperfusion arrhythmias exacerbated by X-XOD and decreased the free radicals generated by X-XOD." | 5.28 | Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat. ( Fu, SX; Li, YL; Li, YS, 1989) |
| " We therefore decided to compare the influence of oral and intravenous administration of furnidipine, nifedipine, nitrendipine and nimodipine to examine their effects on hemodynamics and arrhythmias." | 3.78 | Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine. ( Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B, 2012) |
| "m-Nisoldipine iv 3, 5 and 10 micrograms/kg before coronary artery ligation markedly reduced the early ischemic arrhythmia in conscious rats." | 3.67 | [Effects of m-nisoldipine on ischemic arrhythmia in conscious rats]. ( An, RH; Fu, SX; Li, YS, 1989) |
| "The intravenous administration of either nifedipine (in doses of 5-50 microgram/kg), or nisoldipine (5-1000 microgram/kg) markedly reduced, or abolished, the serious ventricular arrhythmias (tachycardia and fibrillation) that result from acute coronary artery artery ligation in pentobarbitone-anaesthetized rats." | 3.66 | Calcium antagonists prevent early post-infarction ventricular fibrillation. ( Fagbemi, O; Parratt, JR, 1981) |
| "They prevented reperfusion arrhythmias exacerbated by X-XOD and decreased the free radicals generated by X-XOD." | 1.28 | Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat. ( Fu, SX; Li, YL; Li, YS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Splawski, I | 1 |
| Timothy, KW | 1 |
| Sharpe, LM | 1 |
| Decher, N | 1 |
| Kumar, P | 1 |
| Bloise, R | 1 |
| Napolitano, C | 1 |
| Schwartz, PJ | 1 |
| Joseph, RM | 1 |
| Condouris, K | 1 |
| Tager-Flusberg, H | 1 |
| Priori, SG | 1 |
| Sanguinetti, MC | 1 |
| Keating, MT | 1 |
| Mitręga, KA | 1 |
| Varghese, B | 1 |
| Porc, M | 1 |
| Krzemiński, TF | 1 |
| Fagbemi, O | 2 |
| Parratt, JR | 2 |
| Bjørnstad, H | 1 |
| Lathrop, DA | 1 |
| Refsum, H | 1 |
| Li, YL | 2 |
| Fu, SX | 3 |
| Li, YS | 3 |
| An, RH | 1 |
| Thandroyen, FT | 1 |
| Flint, NS | 1 |
| Worthington, MG | 1 |
| Opie, LH | 1 |
| Vatner, SF | 1 |
| Patrick, TA | 1 |
| Knight, DR | 1 |
| Manders, WT | 1 |
| Fallon, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives[NCT04832126] | 100 participants (Anticipated) | Observational | 2018-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for nisoldipine and Arrhythmia
| Article | Year |
|---|---|
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Topics: Abnormalities, Multiple; Action Potentials; Animals; Arrhythmias, Cardiac; Autistic Disorder; Brain; | 2004 |
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Car | 2012 |
Suppression by orally-administered nifedipine, nisoldipine and niludipine of early, life-threatening ventricular arrhythmias resulting from acute myocardial ischaemia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; H | 1981 |
Calcium antagonists prevent early post-infarction ventricular fibrillation.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Hemodynamics; Male; Myocardial Infarction; | 1981 |
Prevention of some hypothermia induced electromechanical changes by calcium channel blockade.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cold Temperatur | 1994 |
Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmias exacerbated by free radical generating system in Langendorff heart of rat.
Topics: Animals; Arrhythmias, Cardiac; Free Radicals; Male; Myocardial Reperfusion Injury; Nisoldipine; Rats | 1989 |
[Effects of m-nisoldipine on ischemic arrhythmia in conscious rats].
Topics: Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; | 1989 |
Arrhythmogenic action of alpha 1-adrenoceptor stimulation in normoxic rat ventricular myocardium: influence of nisoldipine, reduced extracellular Ca2+ and ryanodine.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Arrhythmias, Cardiac; Azepines; Calcium; Calcium Chan | 1987 |
[Prophylactic effects of m-nisoldipine and nisoldipine on reperfusion arrhythmia in hearts of rats].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Fatty Acids, Nonesterified; Free Radicals; Isomerism; Male; | 1988 |
Effects of calcium channel blocker on responses of blood flow, function, arrhythmias, and extent of infarction following reperfusion in conscious baboons.
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Cre | 1988 |