Page last updated: 2024-11-01

nisoldipine and Alloxan Diabetes

nisoldipine has been researched along with Alloxan Diabetes in 3 studies

Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

Research Excerpts

ExcerptRelevanceReference
"This study investigates the efficacy of late intervention with the calcium channel blockers (CCBs) nitrendipine and nisoldipine in preventing development of albuminuria and glomerular hypertrophy in experimental diabetes."3.70Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats. ( Flyvbjerg, A; Grønbaek, H; Nielsen, B; Osterby, R, 2000)
"Nisoldipine, a CaCb agent was given to half of the diabetic rats in a dose of 0."1.30Renal response to volume expansion in streptozotocin-induced diabetic rats: influence of calcium channel blockade. ( Kauker, ML; Patel, KP; Zeigler, DW; Zhang, PL, 1997)
"Nisoldipine treatment for five months prevented a rise in blood pressure in Cohen diabetic rats with Goldblatt hypertension, compared to a significant elevation in untreated controls."1.29Effects of nisoldipine on hypertension and glomerulosclerosis in Cohen diabetic rat with Goldblatt hypertension. ( Cohen, AM; Rosenmann, E; Rosenthal, T, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosenthal, T1
Rosenmann, E1
Cohen, AM1
Patel, KP1
Zhang, PL1
Zeigler, DW1
Kauker, ML1
Nielsen, B1
Grønbaek, H1
Osterby, R1
Flyvbjerg, A1

Other Studies

3 other studies available for nisoldipine and Alloxan Diabetes

ArticleYear
Effects of nisoldipine on hypertension and glomerulosclerosis in Cohen diabetic rat with Goldblatt hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:2

    Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic

1993
Renal response to volume expansion in streptozotocin-induced diabetic rats: influence of calcium channel blockade.
    Diabetes research and clinical practice, 1997, Volume: 35, Issue:2-3

    Topics: Animals; Calcium Channel Blockers; Cohort Studies; Denervation; Diabetes Mellitus, Experimental; Glo

1997
Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:2

    Topics: Albuminuria; Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Ex

2000