Page last updated: 2024-11-01

nisoldipine and Albuminuria

nisoldipine has been researched along with Albuminuria in 7 studies

Nisoldipine: A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina.
nisoldipine : A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Our objective was to compare the effect of a long-acting calcium antagonist (nisoldipine) versus an ACE inhibitor (lisinopril) on albuminuria, arterial blood pressure, and glomerular filtration rate (GFR) in hypertensive IDDM patients with diabetic nephropathy."9.08Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment. ( Boelskifte, S; Jensen, BR; Nielsen, FS; Parving, HH; Rossing, P; Tarnow, L, 1997)
"73 m](-2); mean 24-h ambulatory blood pressure was 108 +/- 3 and 105 +/- 2 mmHg, and albuminuria was 1,554 mg/24 h (95% CI 980-2,465) and 1,033 mg/24 h (760-1,406) in the lisinopril and nisoldipine groups, respectively."5.09Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy. ( Hansen, BV; Jensen, C; Parving, HH; Rossing, P; Tarnow, L, 2000)
"Our objective was to compare the effect of a long-acting calcium antagonist (nisoldipine) versus an ACE inhibitor (lisinopril) on albuminuria, arterial blood pressure, and glomerular filtration rate (GFR) in hypertensive IDDM patients with diabetic nephropathy."5.08Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment. ( Boelskifte, S; Jensen, BR; Nielsen, FS; Parving, HH; Rossing, P; Tarnow, L, 1997)
"This study investigates the efficacy of late intervention with the calcium channel blockers (CCBs) nitrendipine and nisoldipine in preventing development of albuminuria and glomerular hypertrophy in experimental diabetes."3.70Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats. ( Flyvbjerg, A; Grønbaek, H; Nielsen, B; Osterby, R, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ruggenenti, P1
Cravedi, P1
Remuzzi, G1
Schrier, RW2
Estacio, RO2
Jeffers, B1
Rossing, P2
Tarnow, L2
Boelskifte, S1
Jensen, BR1
Nielsen, FS1
Parving, HH2
Molitch, ME1
Nielsen, B1
Grønbaek, H1
Osterby, R1
Flyvbjerg, A1
Jensen, C1
Hansen, BV1
Esler, A1
Mehler, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00311870]Phase 452 participants Interventional1993-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nisoldipine and Albuminuria

ArticleYear
The RAAS in the pathogenesis and treatment of diabetic nephropathy.
    Nature reviews. Nephrology, 2010, Volume: 6, Issue:6

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti

2010

Trials

4 trials available for nisoldipine and Albuminuria

ArticleYear
Appropriate Blood Pressure Control in NIDDM (ABCD) Trial.
    Diabetologia, 1996, Volume: 39, Issue:12

    Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel

1996
Differences between nisoldipine and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment.
    Diabetes, 1997, Volume: 46, Issue:3

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur

1997
Long-term renoprotective effect of nisoldipine and lisinopril in type 1 diabetic patients with diabetic nephropathy.
    Diabetes care, 2000, Volume: 23, Issue:12

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur

2000
Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes.
    Kidney international, 2002, Volume: 61, Issue:3

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes

2002

Other Studies

2 other studies available for nisoldipine and Albuminuria

ArticleYear
Nisoldipine and myocardial infarction.
    The New England journal of medicine, 1998, Jul-09, Volume: 339, Issue:2

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diabetes Mellitus,

1998
Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:2

    Topics: Albuminuria; Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Ex

2000