nipecotic acid has been researched along with Sclerosis in 1 studies
nipecotic acid: RN given refers to cpd without isomeric designation
nipecotic acid : A piperidinemonocarboxylic acid that is piperidine in which one of the hydrogens at position 3 is substituted by a carboxylic acid group.
Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test whether GABA transport is compromised in both the forward (uptake) and reverse (heterotransport) direction in the sclerotic epileptic dentate gyrus, the physiological effects of microapplied GABA and nipecotic acid (NPA; a compound that induces heterotransport) were examined in granule cells in hippocampal slices from kainate (KA)-induced epileptic rats and patients with temporal lobe epilepsy (TLE)." | 3.71 | GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis. ( Patrylo, PR; Spencer, DD; Williamson, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patrylo, PR | 1 |
| Spencer, DD | 1 |
| Williamson, A | 1 |
1 other study available for nipecotic acid and Sclerosis
| Article | Year |
|---|---|
GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis.
Topics: Animals; Biological Transport; Carrier Proteins; Dentate Gyrus; Electrophysiology; Epilepsy; Excitat | 2001 |