Page last updated: 2024-08-23

nimustine and Glioma

nimustine has been researched along with Glioma in 223 studies

Research

Studies (223)

TimeframeStudies, this research(%)All Research%
pre-1990105 (47.09)18.7374
1990's73 (32.74)18.2507
2000's33 (14.80)29.6817
2010's10 (4.48)24.3611
2020's2 (0.90)2.80

Authors

AuthorsStudies
Endo, T; Inoue, T; Saito, R; Sugiyama, S; Tominaga, T1
Chonan, M; Kanamori, M; Nakasato, N; Osawa, SI; Saito, R; Suzuki, H; Tominaga, T; Watanabe, M1
Ikuta, S; Maruyama, T; Muragaki, Y; Nitta, M1
Atta, J; Franz, K; Lemercier, S; Rieger, J; Steinbach, JP; Sulzbacher, A; Thiepold, AL1
Cui, XL; Li, HL; Lin, S; Zhang, JN1
Ding, L; Gao, L; Lv, P; Qi, L; Wang, S; Wang, W; Xu, Y; Zhao, D; Zhong, Y1
Dai, C; Dong, J; Huang, Q; Lan, Q; Li, M; Liu, B; Lu, Z; Ma, J; Ma, X; Xie, T1
Endo, T; Inoue, T; Kawashima, R; Nonaka, H; Ogita, S; Saito, R; Sonoda, Y; Sugiyama, S; Sumiyoshi, A; Tominaga, T1
Eisele, G; Happold, C; Linnebank, M; Roth, P; Steinbach, JP; Weller, M; Wick, W1
Gong, F; Ji, SP; Li, AM; Tai, JL; Zhang, YP; Zheng, CQ1
Fujioka, K; Inaba, N; Ishizawa, S; Kimura, M; Manome, Y; Shibasaki, T; Watanabe, M1
Chen, ZP; Jiang, XB; Mu, YG; Sai, K; Shen, D; Yang, QY; Zhang, XH1
Du, H; Hong, Y; Huang, H; Shen, G; Song, J; Wen, X; Xu, G; Yin, Y; Zhang, X1
Christmann, M; Kaina, B; Meise, R; Tomicic, MT1
Fujii, K; Hori, T; Kobayashi, I; Nagashima, T; Oka, H; Tanaka, S; Utsuki, S; Watanabe, T1
Arai, H; Beppu, T; Fukuda, T; Kamada, K; Nakamura, R; Ogasawara, K; Ogawa, A; Oikawa, H; Takeda, M1
Adachi, G; Inoue, O; Ishikawa, Y; Kakinohana, Y; Kin, S; Murayama, S; Ogawa, K; Saito, A; Toita, T; Yoshii, Y1
Fukumoto, M; Hashimoto, N; Itoh, N; Kono, K; Murai, N; Myoumoto, A; Takahashi, JA; Ueba, T1
Bamberg, M; Koch, R; Krauseneck, P; Müller, B; Weller, M1
Asai, J; Chang, CW; Fujimoto, T; Nagashima, G; Suzuki, R1
Baba, K; Fukami, T; Matsuda, M; Nakasu, S1
Boiardi, A; Botturi, A; Broggi, G; Di Meco, F; Eoli, M; Lamperti, E; Salmaggi, A; Silvani, A; Solari, A1
Bratengeier, K; Flentje, M; Kölbl, O; Ruprecht, K; Vince, GH; Vordermark, D1
Fujii, K; Kobayashi, I; Oka, H; Tanaka, S; Utsuki, S; Yasui, Y1
Shibui, S1
Fujibayashi, Y; Furukawa, T; Kado, H; Kawai, H; Kubota, T; Nakagawa, T; Takamatsu, S; Toyohara, J; Yonekura, Y1
Ido, K; Kubota, T; Matsuda, K; Nakagawa, T; Sakuma, T2
Natsume, A; Wakabayashi, T; Yoshida, J1
Adachi, G; Hyodo, A; Inoue, O; Iraha, S; Kakinohana, Y; Murayama, S; Ogawa, K; Saito, A; Sugimoto, K; Tamaki, W; Toita, T; Yoshii, Y1
Fujiwara, T; Hosoda, K; Kawamura, A; Kohmura, E; Kondoh, T; Mizukawa, K; Sasayama, T; Tanaka, K1
Hasegawa, A; Kamada, T; Mizoe, JE; Takagi, R; Takakura, K; Tsuji, H; Tsujii, H; Yanagi, T1
Berrak, S; Koontz Webb, SE; Wolff, JE; Zhang, M1
Arai, H; Konno, K; Murakami, N; Suzuki, Y; Takeda, N; Tanaka, R; Tanimura, K1
Katakura, R; Kitahara, M; Mori, T; Sasaki, T; Suzuki, J2
Mori, T; Sasaki, T; Sugiyama, S; Suzuki, J2
Itagaki, T; Kaba, K; Morimura, T; Tani, E1
Harada, K; Kiya, K; Okamoto, H; Uozumi, T1
Asari, S; Doi, A; Fujiwara, T; Furuta, T; Matsumoto, K; Moriya, Y; Nakasone, S; Nishimoto, A; Ohnishi, R; Tabuchi, K1
Allen, NJ; Clendenon, NR; Kaneko, S; Kartha, M1
Hayakawa, T; Mogami, H; Nakata, Y; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T2
Harada, K; Kiya, K; Uosumi, T1
Kageyama, N; Kobayashi, T; Shibuya, N; Yoshida, J2
Miki, Y; Nakamura, O; Nomura, K; Ohira, M; Shibui, S; Takakura, K; Watanabe, T1
Handa, H; Teraura, T; Yamashita, J; Yumitori, K2
Ha, YS; Handa, H; Otsuka, SI; Suda, K; Taki, W; Tokuriki, Y; Yamashita, J1
Hokama, Y; Hori, T; Muraoka, K; Numata, H; Saito, Y; Takami, M1
Fujiwara, T; Matsumoto, K; Nakasone, S; Nishimoto, A; Ohnishi, R; Tabuchi, K1
Kohono, T; Matsutani, M; Nagashima, T1
Iwasa, H; Kohno, T; Matsutani, M; Satoh, F; Takakura, K; Yamamoto, H1
Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T5
Muraoka, K1
Abe, H; Aida, T; Iwakuma, T; Kaneko, S; Kashiwaba, T; Kitaoka, K; Sato, M; Tokuda, K; Tsuru, M; Ueno, K1
Ishiwata, Y; Kuwabara, T; Kyuma, Y; Murai, M; Nishimura, S; Shinonaga, M; Yamashita, T1
Inoue, I; Kageyama, N; Kanzaki, M; Nagata, M; Wakabayashi, T; Yoshida, J1
Akanuma, A; Kohno, T; Maehara, T; Nakamura, O; Sano, K; Sato, F; Shitara, N; Takakura, K; Yamamoto, H1
Nakamura, O; Nomura, K; Shibui, S; Watanabe, T1
Hayakawa, T; Kato, A; Mogami, H; Nakata, Y; Ushio, Y; Yamada, K; Yoshida, T1
Tanaka, R1
Katakura, R; Mineura, K; Mori, T; Sasaki, T1
Fujiwara, T; Honma, Y; Kuyama, H; Matsumoto, Y; Nagao, S; Ohkawa, M1
Arai, Y; Kabuto, M; Kitai, R; Kobayashi, H; Kubota, T; Nakagawa, T1
Imahori, T; Kasai, H; Kawamoto, K; Numa, Y; Tsuchida, T1
Kreth, FW; Ostertag, CB; Warnke, PC1
Kohda, K; Koyama, K; Mineura, K; Terashima, I; Watanabe, K1
Felix, R; Golde, G; Gremmler, M; Löffel, J; Maier-Hauff, K; Mischel, M; Seebass, M; Stahl, H; Wust, P1
Hyodo, A; Nose, T; Takada, K; Tsuboi, K; Yoshii, Y1
Andoh, T; Hara, A; Murakawa, T; Niikawa, S; Sakai, N; Yamada, H; Zhang, W1
Ikenaga, M; Izumi, I; Kohda, K; Kowada, M; Mineura, K; Watanabe, K1
Fujita, H; Hotta, T; Ikenaga, M; Ishizaki, K; Isowa, G; Kiya, K; Kurisu, K; Mikami, T; Saito, Y; Uozumi, T1
Kihara, S; Nakagawa, S; Shiraishi, T; Tabuchi, K1
Cazzaniga, S; Charles, HC; Schold, SC; Sostman, HD1
Hara, A; Kobayashi, H; Niikawa, S; Sakai, N; Yamada, H; Zhang, W1
Kuratsu, J; Ushio, Y2
Nakajima, Y; Ohnishi, T; Sasaki, T; Tanaka, M; Terasaki, T; Tsuji, A; Yamashima, T; Yamashita, J1
Hotta, T; Ikenaga, M; Ishizaki, K; Isowa, G; Kiya, K; Kurisu, K; Mikami, T; Saito, Y; Uozumi, T1
Hara, A; Mori, H; Niikawa, S; Sakai, N; Yamada, H; Yoshimi, N; Zhang, W1
Izumi, I; Kowada, M; Mineura, K; Watanabe, K2
Iwadate, Y; Namba, H; Saegusa, T; Sueyoshi, K1
Krossnes, BK; Schem, BC1
Kawamoto, K1
Baillet, F; Capelle, L; Chauveinc, L; Chiras, J; Cornu, P; Delattre, JY; Faillot, T; Martin-Duverneuil, M; Mazeron, JJ; Poisson, M; Sola-Martinez, MT1
Abe, H; Aida, T; Ikeda, J; Kaneko, S; Kashiwaba, T; Kawamoto, T; Mitsumori, K; Saitoh, H; Sawamura, Y1
Hatakeyama, T; Kumon, Y; Nakagawa, K; Ohta, S; Sakaki, S; Zenke, K1
Gomi, A; Hirai, H; Masuzawa, T; Ozawa, K; Sakai, R; Shinoda, S1
Amemiya, Y; Hatake, K; Miura, Y; Miyata, T; Muroi, K; Saito, M1
Abe, M; Nishimura, Y; Sasai, K; Shibamoto, Y; Takahashi, M; Tsutsui, K1
Dichgans, J; Roth, W; Schmidt, C; Weller, M1
Fukuchi, M; Kohda, K; Kowada, M; Mineura, K; Terashima, I1
Asai, A; Kuchino, Y; Nagane, M; Nomura, K; Shibui, S1
Aoyagi, M; Hirakawa, K; Ichimura, K; Nagashima, G; Niimi, Y; Ohno, K; Tamaki, M1
Gomi, A; Ishikawa, T; Kuo, MT; Masuzawa, T1
Gomi, A; Ishikawa, T; Kuo, MT; Masuzawa, T; Shinoda, S1
Marchenko, SV1
Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Tsunoda, S; Tsuzuki, T; Yabuno, T1
Arita, K; Curiel, DT; Goldman, CK; Hama, S; Heike, Y; Kurisu, K; Naruse, I; Saijo, N; Takahashi, M; Yoshioka, H1
Asai, A; Kuchino, Y; Nagane, M; Nomura, K; Oyama, H; Shibui, S1
Horikoshi, T; Naganuma, H; Nukui, H; Ohashi, Y; Ueno, T1
Ghulam Muhammad, AK; Isaka, T; Maruno, M; Nakagawa, H; Nakata, H; Ninomiya, H; Yoshimine, T1
Weller, M; Winter, S1
Amin, MR; Fujii, K; Hori, T; Kamitani, H; Nagashima, T; Oka, H; Tanaka, S; Watanabe, T1
Kubo, O; Takakura, K1
Kohshi, K1
Abe, T; Hikawa, T; Hori, S; Mori, T1
Mima, T; Mori, K; Mostafa, MG1
Arai, H; Beppu, T; Hakozaki, S; Kubo, N; Ogawa, A; Suzuki, M; Wada, T; Yoshida, Y1
Nakanishi, Y; Nomura, K; Shibui, S; Tanaka, M1
Kajita, Y; Mizuno, M; Wakabayashi, T; Yoshida, J1
Fukumoto, M; Hashimoto, N; Kono, K; Mori, H; Takahashi, JA; Ueba, T1
Kito, A; Mizuno, M; Sugita, K; Wakabayashi, T; Yoshida, J1
Fujiwara, T; Honma, Y; Matsumoto, Y; Mino, S; Nagao, S; Tsuchida, T1
Hoshi, A; Kakuto, Y; Kayama, T; Nemoto, K; Ogawa, Y; Sakamoto, K; Takai, Y; Yamada, S; Yoshimoto, T1
Koulousakis, A; Shimizu, K; Sturm, V; Yoshida, TK1
Fujiwara, T; Matsumoto, Y; Nagao, S; Sasaoka, N; Tsuchida, T1
Niikawa, S; Nozawa, Y; Sakai, N; Yamada, H; Zhang, W1
Hyodo, A; Kobayashi, E; Komatsu, Y; Nose, T; Yamada, T; Yoshii, Y1
Beuls, E; Koulousakis, A; Shimizu, K; Sturm, V; Yoshida, TK1
Ishiwata, K; Kameyama, M; Katakura, R; Sato, K; Yoshimoto, T1
Asai, A; Kuchino, Y; Matsutani, M; Nagane, M; Nomura, K; Shibui, S1
Darling, JL; Hoffmann, O; Kraemer, HP; Nikkhah, G; Schachenmayr, W; Schönmayr, R; Tonn, JC1
Fujita, T; Furuta, Y; Murasawa, A; Nakagawa, H; Nakajima, S; Nakamura, H; Niiyama, K; Shibata, H; Taki, T; Tsuruzono, K1
Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T1
Matsutani, M; Nakamura, O; Nomura, K; Takakura, K1
Katakura, R; Kitahara, M; Mashiyama, S; Sasaki, T; Suzuki, J; Takahashi, K2
Daita, G; Fujita, T; Hodozuka, A; Okazaki, S; Sako, K; Takei, H; Yonemasu, Y1
Kawamoto, K; Matsumura, H; Numa, Y1
Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Saito, Y; Uozumi, T1
Hirao, J; Hori, T; Muraoka, K; Nakajima, E; Nishiyama, M; Okamoto, H; Tabuchi, F; Tanaka, S; Tatsuhara, T1
Roosen, K; Schachenmayr, W; Tonn, JC1
Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K2
Bodell, WJ1
Katakura, R; Mashiyama, S; Sasaki, T; Suzuki, J; Takahashi, K; Yoshimoto, T1
Dahl, O; Schem, BC1
Fujita, H; Higano, S; Inugami, A; Kanno, I; Kato, T; Murakami, M; Ogawa, T; Shishido, F; Tomura, N; Uemura, K1
Miyagami, M; Tsubokawa, T1
Sasaoka, N1
Heuser, K1
Kraemer, HP; Schönmayr, R; Tonn, JC1
Miyamachi, K1
Tanaka, S1
Shoin, K; Yamashima, T; Yamashita, J1
Abe, H; Aida, T; Kaneko, S; Sugimoto, S; Tokuda, K1
Maruo, K; Nakamura, O; Nomura, K; Takakura, K; Ueyama, Y3
Mori, K; Moriyama, T; Moroki, J; Shibata, S; Tanaka, K2
Akagi, K; Kawakami, K; Kawamoto, K; Kawamura, Y; Matsumura, H; Numa, Y; Ohyama, A; Oka, N1
Ito, T; Kawakami, K; Kawamoto, K; Kawamura, Y; Matsumura, H; Ohyama, A; Oka, N1
Kageyama, N; Kida, Y; Kobayashi, T; Shibuya, N; Tanaka, T1
Aida, T; Bodell, WJ4
Murakami, N; Onda, K; Suzuki, Y; Tanaka, R; Yamazaki, K1
Enomoto, H; Kageyama, N; Yoshida, J1
Handa, H; Hori, R; Iwakawa, S; Okumura, K; Okumura, T; Tokuriki, Y; Tsukamoto, T; Yamashita, J1
Hondo, H; Sato, I; Suzuki, Y; Takeda, N; Tanaka, R1
Kasahara, E; Miyagami, M; Tazoe, M; Tsubokawa, T1
Hosoya, T; Nakai, O; Takahama, H; Takanashi, T; Yamada, K1
Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K1
Bamberg, M; Budach, W; Sprengel, M; Strehl, K; Stuschke, M1
Bock, WJ; Kiwit, JC; Lins, E; Roosen, N; Schirmer, M2
Bock, WJ; Feinendegen, LE; Herzog, H; Kiwit, JC; Kuwert, T; Langen, KJ; Muzik, O; Roosen, N; Rota Kops, E1
Fushimi, S; Ishino, Y; Itoh, Y; Kowada, M; Mineura, K1
Fushimi, S; Ishino, Y; Kowada, M; Mineura, K; Sasajima, H; Sasaki, J3
Hayashi, M; Ishii, H; Ishii, Y; Kawano, H; Nakatsugawa, S; Satoh, K1
Nagashima, T; Takakura, K1
Mabuchi, E; Matsui, Y; Mogami, H; Moriuchi, S; Park, K; Shimizu, K; Tamura, K; Yamada, M1
Furuta, Y; Murasawa, A; Nakagawa, H; Nakajima, S; Nakajima, Y1
Kageyama, N; Kito, A; Yoshida, J1
Furuta, Y; Masaoka, T; Murasawa, A; Nakagawa, H; Nakajima, S; Nakamura, H; Niiyama, K; Shibata, H; Taki, T1
Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y1
Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M1
Ishizaki, R; Matsutani, M; Nakamura, O; Nomura, K; Shitara, N; Takakura, K1
Jaksche, H; Loew, F; Papavero, L1
Goya, T; Kaji, Y; Kinoshita, K; Kodama, T; Maruoka, N; Moriyama, T; Nonaka, A; Oyama, H; Shimauchi, M; Wakisaka, S1
Kowada, M; Mineura, K; Ogawa, T; Shishido, F; Suda, Y; Uemura, K; Yasuda, T1
Endo, Y; Matsutani, M; Nakamura, O; Nishikawa, K; Sasaki, T; Takakura, K; Tanaka, M; Uchida, H1
Hirabuki, N; Kawai, R; Kozuka, T; Mitomo, M; Miura, T; Murayama, S; Usio, Y1
Aida, T1
Fushimi, S; Itoh, Y; Kowada, M; Mineura, K2
Kanno, S; Kitahara, M; Kuwahara, K; Mashiyama, S; Sasaki, T; Sugiyama, S; Takahashi, K1
Enkaku, F; Ito, H; Shoin, K; Yamamoto, S; Yamashima, T1
Abe, H; Handa, H; Kageyama, N; Kitamura, K; Miwa, T; Mogami, H; Takakura, K; Takeuchi, K; Tanaka, R; Yamamoto, S1
Enomoto, H; Kageyama, N; Kato, K; Kito, A; Wakabayashi, T; Yoshida, J1
Hayakawa, T; Kato, A; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T2
Tokuda, K1
Berger, MS; Rosenblum, ML1
Kageyama, N; Kida, Y; Kobayashi, T; Tanaka, T1
Egawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Yoshida, T1
Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T2
Arita, N; Hayakawa, T; Mogami, H; Mori, S; Nagatani, M; Tzuu-Yuan, H; Ushio, Y; Yoshimine, T1
Adachi, S; Anno, Y; Hori, T; Inagaki, H; Inoue, Y; Muraoka, K; Saito, Y; Sasahara, K1
Kokunai, T; Matsumoto, S; Tamaki, N2
Egawa, T; Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Yoshida, T1
Genka, S; Kosugi, Y; Shitara, N; Takakura, K; Tsujita, Y; Wu, Y1
Arai, K; Endoh, S; Horie, Y; Kuroki, T; Takaku, A1
Katakura, R; Kitahara, M; Sasaki, T; Suzuki, J1
Matsui, Y; Miyao, Y; Mogami, H; Okamoto, Y; Shimizu, K; Tsuda, N; Yamada, M1
Inoue, I; Kageyama, N; Wakabayashi, T; Yoshida, J1
Matsutani, M; Nagashima, T; Orii, H; Tamura, A1
Hoshino, T; Kohno, T; Matsutani, M; Takakura, K1

Reviews

8 review(s) available for nimustine and Glioma

ArticleYear
Regression of Recurrent Spinal Cord High-Grade Glioma After Convection-Enhanced Delivery of Nimustine Hydrochloride: Case Reports and Literature Review.
    Operative neurosurgery (Hagerstown, Md.), 2020, 04-01, Volume: 18, Issue:4

    Topics: Convection; Drug Delivery Systems; Glioma; Humans; Neoplasm Recurrence, Local; Nimustine; Spinal Cord

2020
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Cisplatin; Dacarbazine; Disease-Free Survival; Eflornithine; Glioma; Humans; Mitolactol; Network Meta-Analysis; Nimustine; Probability; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide; Treatment Outcome; Vincristine

2016
[Treatment for malignant glioma].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Glioma; Humans; Nimustine

2005
[Glioma].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Drug Synergism; Genetic Therapy; Glioma; Humans; Interferon-beta; Nimustine; Radiotherapy; Temozolomide

2006
[Hyperthermic treatment of malignant tumors. Possible application to the treatment of brain tumors].
    No shinkei geka. Neurological surgery, 1982, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cobalt Radioisotopes; Culture Techniques; Electrocoagulation; Glioma; Haplorhini; Hot Temperature; Humans; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats; Sarcoma, Experimental

1982
[Chemotherapy of brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Glioma; Humans; Nimustine

1994
[Malignant brain tumor treatment and hyperbaric oxygenation].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Glioma; Humans; Hyperbaric Oxygenation; Nimustine

2000
[Chemical modifiers in radiotherapy].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: 35, Issue:11

    Topics: Brain Neoplasms; Bromodeoxyuridine; Combined Modality Therapy; Glioma; Humans; Immunologic Factors; Interferon Type I; Nimustine; Radiation-Sensitizing Agents

1989

Trials

17 trial(s) available for nimustine and Glioma

ArticleYear
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:7

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Postoperative Complications; Temozolomide; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult

2014
A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Hyperbaric Oxygenation; Interferon-beta; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Nimustine; Radiotherapy Dosage; Survival Rate

2003
Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Progression; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Prognosis; Prospective Studies; Survival Analysis; Teniposide; Treatment Outcome

2003
Local drug delivery in recurrent malignant gliomas.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2005, Volume: 26 Suppl 1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Doxorubicin; Drug Delivery Systems; Drug Therapy, Combination; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Survival Rate; Treatment Outcome

2005
Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
    British journal of cancer, 2006, Oct-09, Volume: 95, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nimustine; Procarbazine; Radiotherapy; Survival Analysis; Treatment Outcome; Vincristine

2006
Phase I/II clinical trial of carbon ion radiotherapy for malignant gliomas: combined X-ray radiotherapy, chemotherapy, and carbon ion radiotherapy.
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carbon Radioisotopes; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Radiotherapy Dosage

2007
Leukoencephalopathy associated with intra-arterial ACNU in patients with gliomas.
    Journal of neuro-oncology, 1995, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Aged; Brain; Brain Diseases; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Infant; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Recurrence; Tomography, X-Ray Computed

1995
Intra-arterial mannitol infusion in the chemotherapy for malignant brain tumors.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Cisplatin; Combined Modality Therapy; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Mannitol; Middle Aged; Nimustine; Survival Rate

1993
Intra arterial chemotherapy with ACNU and radiotherapy in inoperable malignant gliomas.
    Journal of neuro-oncology, 1996, Volume: 27, Issue:2

    Topics: Adult; Aged; Combined Modality Therapy; Drug Administration Schedule; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Nimustine; Survival Rate

1996
Phase II study of DTIC, ACNU, and vincristine combination chemotherapy for supratentorial malignant astrocytomas.
    Neurologia medico-chirurgica, 1996, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Astrocytoma; Child; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Radiation Dosage; Supratentorial Neoplasms; Treatment Outcome; Vincristine

1996
Preliminary individual adjuvant therapy for gliomas based on the results of molecular biological analyses for drug-resistance genes.
    Journal of neuro-oncology, 2000, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Brain Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioma; Humans; Immunohistochemistry; Middle Aged; Multidrug Resistance-Associated Proteins; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prospective Studies; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured

2000
A phase II study of nimustine hydrochloride, cisplatin, and etoposide combination chemotherapy for supratentorial malignant gliomas.
    Journal of neuro-oncology, 2000, Volume: 49, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Survival Analysis; Treatment Outcome

2000
Intratumoral microinfusion of nimustine (ACNU) for recurrent glioma.
    Brain tumor pathology, 2001, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Child; Female; Glioma; Humans; Injections, Intralesional; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Nimustine; Oligodendroglioma; Prospective Studies

2001
[Randomized controlled study on the effect of adjuvant immunotherapy with OK-432 on malignant gliomas].
    Neurologia medico-chirurgica, 1985, Volume: 25, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Biological Products; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Picibanil; Random Allocation

1985
[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage; Tegafur

1985
Effects of ACNU and radiotherapy on malignant glioma.
    Journal of neurosurgery, 1986, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; Glioma; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nimustine; Nitrosourea Compounds

1986
Randomized controlled study of the effect of adjuvant immunotherapy with Picibanil on 51 malignant gliomas.
    Surgical neurology, 1987, Volume: 27, Issue:3

    Topics: Adult; Aged; Biological Products; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Picibanil; Random Allocation; Skin Tests

1987

Other Studies

198 other study(ies) available for nimustine and Glioma

ArticleYear
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
    Neurologia medico-chirurgica, 2020, Jan-15, Volume: 60, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Drug Resistance; Drug Resistant Epilepsy; Female; Follow-Up Studies; Glioma; Humans; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Neurosurgical Procedures; Nimustine; Nitriles; Pyridones; Radiotherapy, Adjuvant; Receptors, AMPA; Retrospective Studies; Temozolomide; Young Adult

2020
[Nimustine hydrochloride/ranimustine efficacy and safety in glioma].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74 Suppl 7

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Nimustine; Nitrosourea Compounds

2016
Prophylactic use of pegfilgrastim in patients treated with a nitrosourea and teniposide for recurrent glioma.
    Pharmacotherapy, 2014, Volume: 34, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Communicable Diseases; Disease-Free Survival; Female; Filgrastim; Germany; Glioma; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Severity of Illness Index; Survival Rate; Teniposide

2014
Hyperbaric oxygen therapy sensitizes nimustine treatment for glioma in mice.
    Cancer medicine, 2016, Volume: 5, Issue:11

    Topics: Animals; Antineoplastic Agents; Biomarkers; Body Weight; Cell Line, Tumor; Disease Models, Animal; Glioma; Humans; Hyperbaric Oxygenation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Mice; Mice, Transgenic; Models, Biological; NF-kappa B; Nimustine; Signal Transduction; Tumor Burden; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays

2016
Convection-enhanced delivery of a hydrophilic nitrosourea ameliorates deficits and suppresses tumor growth in experimental spinal cord glioma models.
    Acta neurochirurgica, 2017, Volume: 159, Issue:5

    Topics: Animals; Antineoplastic Agents; Convection; Drug Delivery Systems; Glioma; Male; Nimustine; Rats; Rats, Inbred F344; Spinal Cord Neoplasms

2017
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Temozolomide

2009
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azacitidine; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Dacarbazine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Survival Rate; Temozolomide; Young Adult

2009
Effect of inhibition of the ROCK isoform on RT2 malignant glioma cells.
    Anticancer research, 2010, Volume: 30, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; Glioma; Humans; Immunoblotting; Isoenzymes; Nimustine; Rats; rho-Associated Kinases; RNA, Small Interfering; Transfection

2010
[Nimotuzumab in combination with chemotherapy for patients with malignant gliomas].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Child; Cisplatin; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Infusions, Intravenous; Male; Nausea; Neutropenia; Nimustine; Temozolomide; Teniposide; Thrombocytopenia; Young Adult

2011
An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human glioma cells.
    International immunopharmacology, 2011, Volume: 11, Issue:11

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Glioma; Humans; Immunohistochemistry; Nimustine; Receptors, Transferrin

2011
The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; DNA Repair; Down-Regulation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Glioma; Humans; Mice; Nimustine; Proto-Oncogene Proteins c-fos; Transcription Factor AP-1

2012
O6-methylguanine-DNA methyltranspherase gene expression in gliomas by means of real-time quantitative RT-PCR and clinical response to nitrosoureas.
    International journal of cancer, 2003, Jan-01, Volume: 103, Issue:1

    Topics: Adult; Antineoplastic Agents; beta 2-Microglobulin; Brain Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Middle Aged; Neoplasm Recurrence, Local; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Rate; Transcription, Genetic

2003
Prospective trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 67, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Hyperbaric Oxygenation; Japan; Male; Middle Aged; Nimustine; Procarbazine; Prospective Studies; Supratentorial Neoplasms; Survival Rate; Vincristine

2003
In vitro growth suppression of human glioma cells by a 16-mer oligopeptide: a potential new treatment modality for malignant glioma.
    Journal of neuro-oncology, 2003, Volume: 63, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cisplatin; Drug Synergism; Etoposide; Fibroblast Growth Factor 2; Glioma; Humans; Nimustine; Oligopeptides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Antisense; Signal Transduction; Tumor Cells, Cultured

2003
[Role of thallium SPECT for evaluating the effect of maintenance chemotherapy against malignant gliomas].
    No shinkei geka. Neurological surgery, 2003, Volume: 31, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Administration Schedule; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon; Vincristine

2003
Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Brain; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Immunohistochemistry; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Radiotherapy; Survival Analysis

2004
Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma.
    BMC cancer, 2005, May-30, Volume: 5

    Topics: Antineoplastic Agents; Brain Neoplasms; Disease Progression; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Nimustine; Prognosis; Radiosurgery; Radiotherapy; Recurrence; Stereotaxic Techniques; Teniposide; Time Factors; Treatment Outcome

2005
Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds.
    Oncology reports, 2005, Volume: 14, Issue:5

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cisplatin; Down-Regulation; Female; Gene Expression Profiling; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2005
Acquisition of resistance to antitumor alkylating agent ACNU: a possible target of positron emission tomography monitoring.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistance, Neoplasm; Fluorodeoxyglucose F18; Glioma; Nimustine; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Rats; Treatment Outcome

2006
Gene expression profiles of 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU)-resistant C6 rat glioma cells.
    Journal of neuro-oncology, 2006, Volume: 79, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Profiling; Glioma; Immunohistochemistry; Nimustine; Oligonucleotide Array Sequence Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction

2006
The combined effects of multiple chemotherapeutic agents for malignant glioma cells.
    Journal of neuro-oncology, 2007, Volume: 84, Issue:1

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Etoposide; Glioma; Humans; Models, Statistical; Nimustine; Vincristine

2007
Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells.
    Journal of neuro-oncology, 2007, Volume: 84, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Glioma; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Neoplasms, Experimental; Nimustine; Protein Kinases; Rats; Rats, Nude; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2007
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cohort Studies; Data Interpretation, Statistical; Databases, Factual; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Nimustine; Nitrosourea Compounds; Reproducibility of Results; Selection Bias; Survival Analysis; Treatment Outcome

2008
[Radiotherapy using bleomycin, ACNU, and vincristine for malignant brain tumors. Efficacy for tumor regression].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bleomycin; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Vincristine

1984
[Combined effect of ACNU and 5-fluorouracil on spheroids of rat glioma cells].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Fluorouracil; Glioma; Nimustine; Nitrosourea Compounds; Rats

1984
[Lethal effect of X-ray and ACNU on cultured rat glioma cells in multicellular spheroids].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Glioma; Nimustine; Nitrosourea Compounds; Rats

1984
Preliminary study of the effects of vitamin A on antineoplastic activities of chemotherapeutic agents in glioma.
    Neurologia medico-chirurgica, 1980, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Survival; Glioma; Humans; In Vitro Techniques; Mice; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Vincristine; Vitamin A

1980
[Comparative studies on anti-tumor effects of nitrosoureas, ACNU and MCNU, on experimental brain tumors (author's transl)].
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Glioma; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds

1981
[Combination chemotherapy of brain tumors with ACNU and 5-FU].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:8

    Topics: Astrocytoma; Biological Products; Brain Neoplasms; Combined Modality Therapy; Drug Therapy, Combination; Ependymoma; Fluorouracil; Glioma; Humans; Lymphoma; Meningeal Neoplasms; Meningioma; Nimustine; Nitrosourea Compounds; Oligodendroglioma; Picibanil

1983
[Treatment schedule of combination using radiation and ACNU in the experimental brain tumors].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; DNA, Neoplasm; Drug Administration Schedule; Glioma; Male; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1983
[Chemotherapy of experimental meningeal gliomatosis].
    Neurologia medico-chirurgica, 1984, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain; Carmustine; Glioma; Male; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
Pharmacokinetics of a new water-soluble nitrosourea derivative (ACNU) in human gliomas.
    Surgical neurology, 1981, Volume: 15, Issue:6

    Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Glioma; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tissue Distribution

1981
[Anti-tumor activity of ACNU against malignant glioma--a clinical application of in vitro sensitivity test of chemotherapeutic agent].
    No shinkei geka. Neurological surgery, 1983, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds

1983
Intensive chemotherapy with autologous bone marrow rescue for recurrent malignant gliomas.
    Neurosurgical review, 1984, Volume: 7, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Male; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds

1984
[Treatment of brain tumor with phenobarbital and continuous infusion of ACNU into internal carotid artery].
    No shinkei geka. Neurological surgery, 1983, Volume: 11, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carotid Artery, Internal; Drug Therapy, Combination; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital

1983
Intra-arterial ACNU therapy for malignant brain tumors. Experimental studies and preliminary clinical results.
    Journal of neurosurgery, 1983, Volume: 59, Issue:3

    Topics: Adult; Animals; Brain Neoplasms; Cell Line; Female; Glioma; Humans; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intravenous; Male; Mice; Middle Aged; Nimustine; Nitrosourea Compounds; Platelet Count; Radiography; Rats; Rats, Inbred Strains

1983
[Study on postoperative local chemotherapy of malignant brain tumors using ACNU and PSK].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:9

    Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carotid Arteries; Drug Therapy, Combination; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Postoperative Period; Proteoglycans

1983
[Effect of ACNU, a water-soluble nitrosourea, on cell cycle of cultured glioma cells--flow cytometric analysis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Glioma; Humans; Mitosis; Nimustine; Nitrosourea Compounds; Rats

1983
[Effects of phenobarbital on the metabolism of ACNU in vivo].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Glioma; Male; Nimustine; Nitrosourea Compounds; Phenobarbital; Rats; Rats, Inbred Strains

1983
[Second-look operations and chemotherapy for malignant tumors of the brain].
    Gan no rinsho. Japan journal of cancer clinics, 1983, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Reoperation; Teniposide

1983
[Meningeal gliomatosis models as a chemosensitivity assay system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Disease Models, Animal; Drug Resistance; Glioma; Male; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
[Enhanced effect of reserpine on growth-inhibitory action of ACNU on ACNU resistance C6 glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Animals; Brain Neoplasms; DNA Repair; Drug Resistance; Drug Synergism; Glioma; Growth Inhibitors; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine

1984
[ACNU delivery to malignant tumor tissue and serum--route of administration and combined use of phenobarbital].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain; Brain Neoplasms; Child, Preschool; Drug Therapy, Combination; Ependymoma; Female; Glioma; Humans; Injections, Intra-Arterial; Kinetics; Lymphoma; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital

1983
[Evaluation of radiation immunochemotherapy in the treatment of malignant glioma. Combined use of ACNU, VCR and PS-K].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1983, Volume: 58, Issue:6

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Glioma; Humans; Middle Aged; Nimustine; Nitrosourea Compounds; Proteoglycans; Vincristine

1983
Treatment of malignant brain tumours with ACNU and phenobarbital: continuous infusion of ACNU into internal carotid artery and systemic administration of phenobarbital.
    Acta neurochirurgica, 1984, Volume: 70, Issue:3-4

    Topics: Adult; Aged; Astrocytoma; Bone Marrow; Brain Neoplasms; Carotid Artery, Internal; Erythrocyte Count; Female; Glioma; Humans; Infusions, Intra-Arterial; Leukocyte Count; Lymphoma; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital; Tomography, X-Ray Computed

1984
[Chemotherapy for experimental subarachnoid dissemination model of brain tumor].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Injections, Intraperitoneal; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Picibanil; Rats; Rats, Inbred Strains

1984
[MCNU effectiveness on brain tumor. Part I: Antitumor activity in vitro on human glioma and neuroblastoma cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line; Cells, Cultured; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Mitosis; Neuroblastoma; Nimustine; Nitrosourea Compounds

1984
[Synchronization chemoradiotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Teniposide; Vincristine

1984
[Flow cytometric study of enhanced effect of anti-cancer drugs induced by nicardipine hydrochloride].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Glioma; Interphase; Methylnitrosourea; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Vincristine

1984
[Development of ACNU-resistant meningeal gliomatosis models: establishment of resistant rat glioma subline against ACNU].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; Drug Resistance; Glioma; Male; Meningeal Neoplasms; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1984
[Therapeutic effects of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and radiation on the rat glioma (author's transl)].
    No shinkei geka. Neurological surgery, 1981, Volume: 9, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Glioma; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats

1981
Sensitivity to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) of glioma cells in vivo and in vitro.
    Cancer, 1982, Aug-01, Volume: 50, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line; Drug Evaluation, Preclinical; Glioma; Humans; Kinetics; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats

1982
A comparison of intraarterial carboplatin and ACNU for the treatment of gliomas.
    Surgical neurology, 1995, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Carboplatin; Child; Drug Therapy; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; Treatment Outcome

1995
Experimental study of intraoperative local chemotherapy with fibrin glue containing nitrosourea for malignant gliomas.
    Surgical neurology, 1995, Volume: 44, Issue:2

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy; Fibrin Tissue Adhesive; Glioma; Male; Nimustine; Rats; Rats, Wistar; Time Factors; Treatment Outcome

1995
[Effective measures against side effects by increasing ACNU dose for malignant glioma: effects on digestive organs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:12

    Topics: Adult; Aged; Anorexia; Brain Neoplasms; Drug Therapy, Combination; Female; Glioma; Granisetron; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Nausea; Nimustine; Vomiting

1994
Long-term follow-up results of 175 patients with malignant glioma.
    Acta neurochirurgica, 1994, Volume: 131, Issue:1-2

    Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Follow-Up Studies; Glioma; Humans; Interferons; Nimustine; Radiotherapy, Adjuvant; Survival Rate; Treatment Outcome

1994
Potentiation of the cytotoxicity of chloroethylnitrosourea by O6-arylmethylguanines.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:3

    Topics: Alkylation; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Drug Synergism; Glioma; Guanine; HeLa Cells; Humans; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Phenols; Prohibitins; Rats; Tumor Cells, Cultured

1995
[The use of an early postoperative interstitial-hyperthermia combination therapy in malignant gliomas].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1995, Volume: 171, Issue:9

    Topics: Antineoplastic Agents; Brachytherapy; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Glioma; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Nimustine; Pilot Projects; Postoperative Care; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Time Factors; Tomography, X-Ray Computed

1995
Effect of interferon-gamma on ACNU-induced DNA damage and cytotoxicity in human glioblastoma cells.
    Neurologia medico-chirurgica, 1993, Volume: 33, Issue:5

    Topics: Brain Neoplasms; Cell Line; Cell Survival; DNA Damage; Drug Synergism; Glioma; Humans; Interferon-gamma; Microscopy, Fluorescence; Nimustine; Tumor Cells, Cultured

1993
Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
    Acta neurochirurgica, 1994, Volume: 128, Issue:1-4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Basal Ganglia; Brain Neoplasms; Cell Count; Cell Division; Culture Techniques; DNA Repair; DNA, Neoplasm; Drug Synergism; Glioma; Guanine; Male; Nimustine; Rats; Rats, Wistar

1994
O6-alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications.
    Journal of neuro-oncology, 1994, Volume: 21, Issue:2

    Topics: Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Glioblastoma; Glioma; Humans; Methyltransferases; Neoplasm Proteins; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Tetrazolium Salts; Thiazoles

1994
Induced expression and subcellular localization of the Bcl-2 protein in cultured glioma cells.
    Noshuyo byori = Brain tumor pathology, 1994, Volume: 11, Issue:2

    Topics: Blotting, Southern; Brain Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Microscopy, Confocal; Nimustine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1994
Effects of therapy on the 1H NMR spectrum of a human glioma line.
    Magnetic resonance imaging, 1994, Volume: 12, Issue:6

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Lactates; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nimustine; Tumor Cells, Cultured

1994
A single cell gel electrophoresis technique for the detection of DNA damage induced by ACNU, an alkylating agent or irradiation in murine glioma cell lines.
    Neurological research, 1994, Volume: 16, Issue:4

    Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Glioma; Kinetics; Nimustine; Rats; Tumor Cells, Cultured; X-Rays

1994
Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma.
    Experimental brain research, 1993, Volume: 95, Issue:1

    Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Capillaries; Carrier Proteins; Cerebral Cortex; Drug Resistance; Fluorouracil; Glioma; Hippocampus; Male; Membrane Glycoproteins; Mesencephalon; Microscopy, Electron; Microscopy, Immunoelectron; Nimustine; Rats; Rats, Inbred F344; Sucrose; Tumor Cells, Cultured; Venules

1993
Interrelationship between O6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:1

    Topics: Animals; Drug Resistance; Glioma; Humans; Interferon-beta; Methyltransferases; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tumor Cells, Cultured

1993
Identification of placental form of glutathione S-transferase in ACNU-resistant murine glioma cell lines.
    Journal of neuro-oncology, 1993, Volume: 17, Issue:3

    Topics: Animals; Blotting, Northern; Blotting, Western; Drug Resistance; Glioma; Glutathione Transferase; Mice; Nimustine; Placenta; Tumor Cells, Cultured

1993
Influence of O6-methylguanine-DNA methyltransferase activity on chloroethylnitrosourea chemotherapy in brain tumors.
    International journal of cancer, 1993, Aug-19, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Follow-Up Studies; Glioma; Humans; Male; Methyltransferases; Middle Aged; Neoplasms, Nerve Tissue; Nimustine; O(6)-Methylguanine-DNA Methyltransferase

1993
Enhancement of ACNU treatment of the BT4An rat glioma by local brain hyperthermia and intra-arterial drug administration.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:11

    Topics: Animals; Brain Neoplasms; Combined Modality Therapy; Glioma; Hyperthermia, Induced; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nimustine; Random Allocation; Rats; Rats, Inbred Strains; Survival Rate

1995
[Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents].
    Human cell, 1995, Volume: 8, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cisplatin; Flow Cytometry; Glioma; Humans; Interferons; Nimustine; Prostaglandin D2; Tumor Cells, Cultured

1995
A strategy for selective anti-cancer drug concentration increase in rat glioma tissue with Ca(2+)-channel blocker co-administration: calcium kinetics in intra-glioma arteriolar smooth muscle cells.
    Journal of neuro-oncology, 1996, Volume: 30, Issue:1

    Topics: Animals; Antineoplastic Agents; Arterioles; Brain Neoplasms; Calcium; Calcium Channel Blockers; Diltiazem; Glioma; Kinetics; Male; Muscle, Smooth, Vascular; Nimustine; Rats; Rats, Wistar; Reference Values; Regional Blood Flow; Tumor Cells, Cultured

1996
Elevated expression of DNA polymerase beta gene in glioma cell lines with acquired resistance to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea.
    Biochemical and biophysical research communications, 1996, Oct-14, Volume: 227, Issue:2

    Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Cell Line; DNA Polymerase I; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Nimustine; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1996
Therapy-related chronic myelomonocytic leukaemia with bone marrow eosinophilia associated with der(11)t(1;11)(q21;q14).
    Acta haematologica, 1996, Volume: 96, Issue:4

    Topics: Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Child; Chromosome Aberrations; Eosinophilia; Fatal Outcome; Glioma; Humans; Hydroxyurea; Karyotyping; Leukemia, Myelomonocytic, Chronic; Leukocyte Count; Lymphocyte Activation; Male; Nimustine

1996
Comparison of accelerated hyperfractionated radiotherapy and conventional radiotherapy for supratentorial malignant glioma.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:1

    Topics: Adult; Antineoplastic Agents; Female; Glioma; Humans; Interferon-beta; Male; Middle Aged; Multivariate Analysis; Nimustine; Prognosis; Radiotherapy Dosage; Supratentorial Neoplasms; Survival Rate

1997
Chemotherapy of human malignant glioma: prevention of efficacy by dexamethasone?
    Neurology, 1997, Volume: 48, Issue:6

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Cell Cycle; Cell Survival; Cytarabine; Dexamethasone; Doxorubicin; Drug Interactions; Glioma; Humans; Methotrexate; Nimustine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Teniposide; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vincristine

1997
[Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
    No to shinkei = Brain and nerve, 1997, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glioma; Guanine; Humans; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Tumor Cells, Cultured

1997
Application of antisense ribonucleic acid complementary to O6-methylguanine-deoxyribonucleic acid methyltransferase messenger ribonucleic acid for therapy of malignant gliomas.
    Neurosurgery, 1997, Volume: 41, Issue:2

    Topics: Animals; Antineoplastic Agents; Antisense Elements (Genetics); Drug Resistance, Neoplasm; Glioma; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Protein Biosynthesis; Rats; RNA, Complementary; RNA, Messenger; Transfection; Tumor Cells, Cultured

1997
Parenchymal damage in the territory of the anterior choroidal artery following supraophthalmic intracarotid administration of CDDP for treatment of malignant gliomas.
    Journal of neuro-oncology, 1997, Volume: 35, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carotid Arteries; Choroid Plexus; Cisplatin; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Retrospective Studies; Tomography, X-Ray Computed

1997
Posttranscriptional regulation of MRP/GS-X pump and gamma-glutamylcysteine synthetase expression by 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea and by cycloheximide in human glioma cells.
    Biochemical and biophysical research communications, 1997, Oct-09, Volume: 239, Issue:1

    Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Carrier Proteins; Cycloheximide; Dactinomycin; Glioma; Glutamate-Cysteine Ligase; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Nimustine; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; RNA, Messenger; Tumor Cells, Cultured

1997
Transient induction of the MRP/GS-X pump and gamma-glutamylcysteine synthetase by 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea in human glioma cells.
    Cancer research, 1997, Dec-01, Volume: 57, Issue:23

    Topics: Amino Acid Sequence; Animals; Antibodies; Antineoplastic Agents; Arsenates; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioma; Glutamate-Cysteine Ligase; Glutathione; Humans; Leukotriene C4; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Models, Biological; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Nimustine; Peptide Fragments; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1997
[Comprehensive therapy of malignant glioma of the brain].
    Voprosy onkologii, 1997, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Glioma; Humans; Infant; Middle Aged; Nimustine; Radioimmunotherapy; Survival Analysis; Treatment Outcome

1997
Drug resistance and apoptosis in ENU-induced rat brain tumors treated with anti-cancer drugs.
    Journal of neuro-oncology, 1998, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Nimustine; Pregnancy; Rats; Rats, Wistar; Vincristine

1998
Adenovirus-mediated p16 gene transfer prevents drug-induced cell death through G1 arrest in human glioma cells.
    International journal of cancer, 1998, Jul-03, Volume: 77, Issue:1

    Topics: Adenoviridae; Antineoplastic Agents; Cell Death; Cyclin-Dependent Kinase Inhibitor p16; Drug Resistance, Neoplasm; G1 Phase; Gene Transfer Techniques; Genetic Vectors; Glioma; Humans; Nimustine; Tumor Cells, Cultured

1998
Expression pattern of chemoresistance-related genes in human malignant brain tumors: a working knowledge for proper selection of anticancer drugs.
    Japanese journal of clinical oncology, 1999, Volume: 29, Issue:11

    Topics: Antigens, CD; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Doxorubicin; Etoposide; Genes, MDR; Glioma; Humans; Membrane Glycoproteins; Nimustine; RNA, Messenger; Tetraspanin 29; Tumor Cells, Cultured

1999
Enhancing effect of electric stimulation on cytotoxicity of anticancer agents against rat and human glioma cells.
    Brain research bulletin, 2000, Mar-15, Volume: 51, Issue:5

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carboplatin; Cell Division; Electric Stimulation; Etoposide; Glioma; Humans; Nimustine; Rats; Tumor Cells, Cultured; Vincristine

2000
Effectiveness of spray application of ACNU in the local control of malignant gliomas: report of two cases.
    Neurological research, 2000, Volume: 22, Issue:2

    Topics: Aerosols; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Combinations; Fibrin Tissue Adhesive; Follow-Up Studies; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Postoperative Care; Tissue Adhesives

2000
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioma; Humans; Lomustine; Methylnitrosourea; Mitosis; Nimustine; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured

2000
Treatment of malignant brain tumors.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Prognosis; Radiosurgery; Survival Rate; Vincristine

2000
The ability in adhesion and invasion of drug-resistant human glioma cells.
    Journal of experimental & clinical cancer research : CR, 2000, Volume: 19, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Adhesion; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Extracellular Matrix Proteins; Flow Cytometry; Glioma; Humans; Matrix Metalloproteinases; Mice; Neoplasm Proteins; Neural Cell Adhesion Molecules; Nimustine; Tumor Cells, Cultured; Vincristine

2000
Antitumor effect and peritumoral brain edema formation in relation to MX2, ACNU, and doxorubicin therapy: a comparative analysis using rodent models of gliomas.
    Neurological research, 2000, Volume: 22, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Body Weight; Brain Edema; Brain Neoplasms; Carubicin; Disease Models, Animal; Doxorubicin; Glioma; Leukocyte Count; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nimustine; Rats; Survival Rate

2000
Radiotherapy combined with nimustine hydrochloride and etoposide for malignant gliomas: results of a pilot study.
    Japanese journal of clinical oncology, 2001, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Disease-Free Survival; Etoposide; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Pilot Projects; Prognosis; Supratentorial Neoplasms

2001
Effects of combination chemotherapy with biscoclaurine-derived alkaloid (Cepharanthine) and nimustine hydrochloride on malignant glioma cell lines.
    Journal of neuro-oncology, 2002, Volume: 56, Issue:2

    Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylisoquinolines; Caspase Inhibitors; Cell Division; Central Nervous System Neoplasms; Genes, p53; Glioma; Humans; Nimustine; Oligopeptides; Tumor Cells, Cultured

2002
Effectiveness of interferon-beta, ACNU, and radiation therapy in pediatric patients with brainstem glioma.
    Neurologia medico-chirurgica, 1992, Volume: 32, Issue:13

    Topics: Adolescent; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Combined Modality Therapy; Female; Glioma; Humans; Interferon-beta; Magnetic Resonance Imaging; Male; Nimustine

1992
[Intra-arterial chemotherapy with ACNU in the treatment of malignant gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carotid Artery, Internal; Female; Glioblastoma; Glioma; Humans; Infant, Newborn; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Prognosis; Tomography, X-Ray Computed

1992
Treatment results by uneven fractionated irradiation, low-dose rate telecobalt therapy as a boost, and intraoperative irradiation for malignant glioma.
    The Tohoku journal of experimental medicine, 1992, Volume: 167, Issue:4

    Topics: Adolescent; Adult; Aged; Brain; Brain Neoplasms; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Necrosis; Nimustine; Prognosis; Radioisotope Teletherapy; Regression Analysis

1992
Intrathecal chemotherapy with ACNU in a meningeal gliomatosis rat model.
    Journal of neurosurgery, 1992, Volume: 77, Issue:5

    Topics: Animals; Disease Models, Animal; Glioma; Injections, Spinal; Male; Meningeal Neoplasms; Nimustine; Rats; Rats, Wistar

1992
[Quantitative analysis of glutathione and glutathione S-transferase in human brain tumors, C6 rat glioma cells and drug resistant C6 cells].
    No shinkei geka. Neurological surgery, 1992, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Drug Resistance; Glioma; Glutathione; Glutathione Transferase; Nimustine; Rats; Tumor Cells, Cultured; Vincristine

1992
Enhancement of radiosensitivity by tamoxifen in C6 glioma cells.
    Neurosurgery, 1992, Volume: 31, Issue:4

    Topics: Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Glioma; Humans; Nimustine; Protein Kinase C; Radiation-Sensitizing Agents; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay

1992
Malignancy and viability of intraparenchymal brain tumours: correlation between Gd-DTPA contrast MR images and proliferative potentials.
    Acta neurochirurgica, 1992, Volume: 117, Issue:3-4

    Topics: Brain; Brain Neoplasms; Cell Division; Cell Survival; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Gadolinium DTPA; Glioma; Humans; Magnetic Resonance Imaging; Nimustine; Organometallic Compounds; Pentetic Acid; Premedication; Radiation Injuries

1992
Intrathecal chemotherapy with ACNU for meningeal gliomatosis.
    British journal of cancer, 1992, Volume: 66, Issue:6

    Topics: Animals; Drug Administration Schedule; Glioma; Injections, Spinal; Male; Meningeal Neoplasms; Nimustine; Rats; Rats, Inbred F344; Rats, Wistar

1992
Modulation of BUdR labeling index in rat brain tumors following intracarotid ACNU administration.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:3

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carotid Arteries; Cell Division; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Neoplasm Transplantation; Nimustine; Rats; Time Factors; Tumor Cells, Cultured

1992
Metabolic changes of glioma following chemotherapy: an experimental study using four PET tracers.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:1

    Topics: Animals; Body Weight; Carbon Radioisotopes; Deoxyglucose; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorine Radioisotopes; Glioma; Groin; Male; Methionine; Neoplasm Proteins; Neoplasm Transplantation; Nimustine; Rats; Rats, Wistar; RNA, Neoplasm; Survival Rate; Thymidine; Tomography, Emission-Computed; Tritium

1992
Expression of O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea resistance of human brain tumors.
    Japanese journal of clinical oncology, 1992, Volume: 22, Issue:3

    Topics: Blotting, Northern; Brain Neoplasms; Cell Survival; DNA Probes; Drug Resistance; Glioma; Humans; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured

1992
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Glioma; Humans; Mitomycin; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1992
[Treatment of malignant gliomas by selective intraarterial infusion chemotherapy with high-dose ACNU and autologous bone marrow transplantation--preliminary report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:14

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Transplantation, Autologous

1991
Hypersensitivity of rat glioma sublines with acquired ACNU resistance to L-asparaginase.
    Journal of neurosurgery, 1991, Volume: 75, Issue:6

    Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Cell Division; Drug Resistance; Glioma; Nimustine; Rats; Tumor Cells, Cultured

1991
[Drug sensitivity test against malignant gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Humans; Interferons; Mice; Mice, Inbred C57BL; Mitomycin; Mitomycins; Neoplasm Transplantation; Nimustine; Vincristine

1990
Effects of X-irradiation alone and in combination with ACNU on human glioblastoma cells in vitro.
    Neurologia medico-chirurgica, 1990, Volume: 30, Issue:5

    Topics: Cell Line; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Radiation; Glioma; Humans; Nimustine; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Diffuse low-density areas in white matter on CT scans after intracarotid ACNU infusion--report of three cases.
    Neurologia medico-chirurgica, 1990, Volume: 30, Issue:9

    Topics: Brain; Brain Neoplasms; Carotid Arteries; Female; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Nimustine; Tomography, X-Ray Computed

1990
[Multidisciplinary therapy using interferon and immunological evaluation for glioma patients: two-color analysis of T cell subsets].
    No shinkei geka. Neurological surgery, 1991, Volume: 19, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Interferons; Male; Middle Aged; Nimustine; Picibanil; Radiotherapy Dosage; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory

1991
[Establishment of ACNU-resistant rat gliosarcoma cell lines and their characteristics].
    Neurologia medico-chirurgica, 1991, Volume: 31, Issue:13

    Topics: Animals; Cell Separation; Drug Resistance; Drug Screening Assays, Antitumor; Glioma; Karyotyping; Microscopy, Electron; Mutation; Nimustine; Rats; Tumor Cells, Cultured

1991
[Intrathecal distribution of ACNU by various modes of its administration analyzed by HPLC and autoradiography].
    No to shinkei = Brain and nerve, 1991, Volume: 43, Issue:9

    Topics: Animals; Autoradiography; Brain Neoplasms; Chromatography, High Pressure Liquid; Cisterna Magna; Dogs; Glioma; Injections, Intraventricular; Injections, Spinal; Nimustine; Perfusion

1991
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
    Journal of neuro-oncology, 1991, Volume: 11, Issue:3

    Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Glioma; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Necrosis; Nimustine; Prospective Studies; Radiation Injuries

1991
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
    International journal of cancer, 1991, Jul-30, Volume: 48, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine

1991
Molecular dosimetry of sister chromatid exchange induction in 9L cells treated with 6-thioguanine.
    Mutagenesis, 1991, Volume: 6, Issue:3

    Topics: Alkylating Agents; Animals; DNA Damage; Dose-Response Relationship, Drug; Ethylnitrosourea; Glioma; Nimustine; Rats; Sister Chromatid Exchange; Thioguanine; Tumor Cells, Cultured

1991
[Effect of X-rays combined with ACNU and O6-ethylguanine on rat subcutaneous gliomas].
    No shinkei geka. Neurological surgery, 1991, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Combined Modality Therapy; Glioma; Guanine; Male; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred Strains; Skin Neoplasms; Tumor Cells, Cultured

1991
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Glioma; Glucose; Hydrogen-Ion Concentration; Hyperthermia, Induced; Hypertonic Solutions; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred Strains; Retinal Diseases; Skin Neoplasms; Tumor Cells, Cultured

1991
Cross-resistance patterns in ACNU-resistant glioma sublines in culture.
    Journal of neurosurgery, 1991, Volume: 75, Issue:2

    Topics: Animals; Brain Neoplasms; Clone Cells; Doxorubicin; Drug Resistance; Glioma; Glutathione; Hot Temperature; Nimustine; Phenotype; Radiation Tolerance; Rats; Rats, Inbred F344; Vinblastine

1991
[The changes of cerebral blood flow and metabolism of normal brain tissue after surgery, radiation, and chemotherapy in brain tumor patients: evaluated by position emission tomography].
    No to shinkei = Brain and nerve, 1990, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; Radiotherapy Dosage; Tegafur; Tomography, Emission-Computed

1990
[Chemotherapy with ACNU and radiation therapy in malignant glioma in cerebral hemisphere of adult].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 1

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Glioma; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Mannitol; Middle Aged; Nimustine; Remission Induction; Retrospective Studies; Survival Rate

1990
[Chemosensitivity assays for malignant gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Drug Screening Assays, Antitumor; Glioma; Humans; Male; Nimustine; Rats; Rats, Inbred F344; Vincristine

1990
[Chemotherapy in malignant gliomas].
    Neurochirurgia, 1990, Volume: 33 Suppl 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up Studies; Glioma; Humans; Nimustine; Survival Rate; Teniposide

1990
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured

1990
[Chemotherapy responsiveness of brain tumors in subrenal capsule assay].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1990, Volume: 65, Issue:1

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Glioma; Male; Nimustine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Subrenal Capsule Assay; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine

1990
[Application of interleukin 1 in the treatment of malignant gliomas with special reference to the experimental combination therapy with ACNU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Glioma; Interferon Type I; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nimustine; Tumor Cells, Cultured

1990
Neurotoxicity of local administration of two nitrosoureas in malignant gliomas.
    Neurosurgery, 1990, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Dose-Response Relationship, Drug; Female; Glioma; Humans; Male; Middle Aged; Neurotoxins; Nimustine; Nitrosourea Compounds

1990
Modification of tumor blood flow and enhancement of therapeutic effect of ACNU on experimental rat gliomas with angiotensin II.
    Journal of neuro-oncology, 1990, Volume: 8, Issue:3

    Topics: Angiotensin II; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Hypertension; Nimustine; Rats; Rats, Inbred Strains

1990
Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro.
    Journal of neurosurgery, 1990, Volume: 73, Issue:3

    Topics: Animals; Glioma; Nimustine; Platelet-Derived Growth Factor; Pyrimidines; Suramin; Time Factors; Trapidil; Tumor Cells, Cultured

1990
[Antineoplastic effect of Hu-IFN-beta and other anticancer drugs on malignant brain tumors in athymic nude mice].
    No shinkei geka. Neurological surgery, 1985, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Ependymoma; Glioblastoma; Glioma; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Nude; Nimustine; Nitrosourea Compounds; Vincristine

1985
[Effect of combined treatment of x-rays and ACNU on rat glioma cells in monolayer and multicellular spheroids].
    Neurologia medico-chirurgica, 1985, Volume: 25, Issue:9

    Topics: Animals; Cell Survival; Cells, Cultured; Combined Modality Therapy; Cytological Techniques; Glioma; Necrosis; Nimustine; Nitrosourea Compounds; Radiation Effects; Rats

1985
[Multidisciplinary therapy for gliomas. Experimental study using brain tumor-bearing rats and analytical study of clinical cases].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:2

    Topics: Animals; Astrocytoma; Biological Products; Brain Neoplasms; Cobalt Radioisotopes; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Picibanil; Rats

1986
[Flow cytometric studies of brain tumors--5: New sensitivity test of antineoplastic agents for brain tumors and its clinical application].
    No shinkei geka. Neurological surgery, 1986, Volume: 14, Issue:5

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Cell Cycle; Cell Survival; Colony-Forming Units Assay; Flow Cytometry; Fluorouracil; Glioma; Humans; Infant; Medulloblastoma; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay

1986
[In vitro response characteristics of brain tumor cell lines to hyperthermia].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; Glioma; Hot Temperature; Humans; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay

1986
[Interaction of human fibroblast interferon with chemotherapeutic agents and radiation of human gliomas in nude mice].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Glioma; Interferon Type I; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage

1986
[Enhancing effect of reserpine upon the cytotoxicity of ACNU on ACNU-resistant glioma cells].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Membrane Permeability; Cells, Cultured; Drug Resistance; Drug Synergism; Glioma; Nimustine; Nitrosourea Compounds; Rats; Reserpine

1986
[Mechanism of cellular resistance to ACNU in rat brain tumor cell line].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; DNA Repair; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats; Sister Chromatid Exchange; Tumor Stem Cell Assay

1986
[DNA content and sensitivity to ACNU of human glioma cell lines].
    Neurologia medico-chirurgica, 1986, Volume: 26, Issue:12

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Cell Line; DNA, Neoplasm; Female; Glioma; Humans; Male; Nimustine; Nitrosourea Compounds

1986
The effectiveness of combination therapy with Hu IFN-beta and ACNU against malignant glioma.
    Neurologia medico-chirurgica, 1987, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Glioma; Humans; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds

1987
[Pharmacokinetics in intra-arterial ACNU therapy in malignant brain tumors].
    Neurologia medico-chirurgica, 1987, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Child; Female; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tissue Distribution

1987
[Mechanisms of cellular resistance to ACNU in cell lines derived from human brain tumors].
    Neurologia medico-chirurgica, 1987, Volume: 27, Issue:9

    Topics: Brain Neoplasms; Drug Resistance; Glioma; Humans; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured

1987
[Computed tomographic features of cerebral malignant glioma following treatment and regrowth. Tumor response to radiochemotherapy].
    Neurologia medico-chirurgica, 1988, Volume: 28, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Child; Combined Modality Therapy; Follow-Up Studies; Glioma; Humans; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Tomography, X-Ray Computed; Vincristine

1988
[Enhancement of the effect of X-irradiation against cultured human glioblastoma cells by pretreatment with ACNU].
    Neurologia medico-chirurgica, 1989, Volume: 29, Issue:12

    Topics: Brain Neoplasms; Cell Survival; Glioma; Humans; Nimustine; Tumor Cells, Cultured

1989
[Therapeutic efficacy of intracarotid infusion of 20% mannitol with ACNU in Fischer rats with intracerebrally implanted 9L gliosarcoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Bromodeoxyuridine; Carotid Artery, Internal; Cell Division; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Infusions, Intra-Arterial; Infusions, Parenteral; Male; Mannitol; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred F344

1989
[Intra-arterial chemotherapy of malignant glioma after osmotic blood-brain barrier disruption].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Glioma; Humans; Infusions, Intra-Arterial; Interferon Type I; Leukopenia; Male; Mannitol; Middle Aged; Nimustine; Osmotic Pressure; Remission Induction; Thrombocytopenia

1989
[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain; Brain Neoplasms; Carbon Radioisotopes; Cerebrovascular Circulation; Combined Modality Therapy; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glioma; Humans; Male; Middle Aged; Nimustine; Oxygen Radioisotopes; Tegafur; Tomography, Emission-Computed

1989
Treatment of high grade glioma xenografts with nitrosoureas in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Carmustine; Glioblastoma; Glioma; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Oligodendroglioma; Transplantation, Heterologous

1989
Adjuvant intraarterial chemotherapy with nimustine in the management of World Health Organization Grade IV gliomas of the brain. Experience at the Department of Neurosurgery of Düsseldorf University.
    Cancer, 1989, Nov-15, Volume: 64, Issue:10

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Neoplasm Staging; Nimustine; Radiotherapy Dosage; World Health Organization

1989
Early effects of intra-arterial chemotherapy in patients with brain tumours studied with PET: preliminary results.
    Nuclear medicine communications, 1989, Volume: 10, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Deoxy Sugars; Deoxyglucose; Female; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Predictive Value of Tests; Prognosis; Tomography, Emission-Computed

1989
Microspectrofluorometric evaluation of single- and double-stranded DNA in short-term cultured human glioma cells.
    Neurological research, 1989, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Child; DNA; DNA, Neoplasm; Female; Glioma; Humans; Infant; Male; Middle Aged; Nimustine; Polyploidy; Spectrometry, Fluorescence; Tumor Cells, Cultured

1989
[Chemotherapeutic strategy in rat brain tumor cells resistant to ACNU using an in vitro colony formation assay].
    No to shinkei = Brain and nerve, 1989, Volume: 41, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Nimustine; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
[A trial of ACNU and radiation therapy with sensitizing agents for malignant gliomas].
    No to shinkei = Brain and nerve, 1989, Volume: 41, Issue:11

    Topics: Acyclovir; Adolescent; Adult; Aged; Brain Neoplasms; Bromodeoxyuridine; Combined Modality Therapy; Evaluation Studies as Topic; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Vidarabine

1989
[Antitumor efficacy of FK 973 on malignant glioma cells].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Methotrexate; Mice; Mice, Inbred C3H; Nimustine; Oxazines

1989
[Concentration of ACNU in a branch of middle cerebral artery, femoral vein and brain tissue by intracarotid or intravenous administration in a patient with recurrent glioblastoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 1

    Topics: Adult; Brain; Brain Neoplasms; Carotid Artery, Internal; Cerebral Arteries; Female; Femoral Vein; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Neoplasm Recurrence, Local; Nimustine; Tissue Distribution

1989
[Controlled multimodality treatment of brain stem gliomas].
    No shinkei geka. Neurological surgery, 1987, Volume: 15, Issue:7

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Interferon Type I; Male; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage

1987
[Treatment of malignant gliomas with high-dose ACNU and autologous bone marrow transplantation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:11

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Transplantation, Autologous

1988
Interactions of human fibroblast interferon with chemotherapeutic agents and radiation against human gliomas in nude mice.
    Neurological research, 1986, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Doxorubicin; Female; Glioma; Interferon Type I; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds

1986
[Circumvention of ACNU-resistance in rat glioma cells by pretreatment with O6-methylguanine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Survival; Drug Resistance; Drug Synergism; Enzyme Induction; Glioma; Guanine; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Intra-arterial chemotherapy with ACNU for the treatment of glioblastoma. Preliminary experience.
    Acta radiologica. Supplementum, 1986, Volume: 369

    Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine

1986
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
    No shinkei geka. Neurological surgery, 1986, Volume: 14, Issue:10

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysgerminoma; Ependymoma; Fluorouracil; Glioma; Humans; Medulloblastoma; Methylmethacrylates; Mitomycin; Mitomycins; Neoplasms, Germ Cell and Embryonal; Nimustine; Nitrosourea Compounds; Teratoma

1986
[Treatment of autochthonous rat brain tumors with chemotherapy and radiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Brain Neoplasms; Carboxymethylcellulose Sodium; Combined Modality Therapy; Glioma; Nimustine; Nitrosourea Compounds; Poly I-C; Polylysine; Radiotherapy Dosage; Rats; Sarcoma, Avian; Vincristine

1987
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
    Acta neurochirurgica, 1987, Volume: 85, Issue:3-4

    Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Studies; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Oligodendroglioma

1987
[AUFRAP therapy: combined modality treatment of malignant gliomas with intraarterial infusion of ACNU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotid Artery, Internal; Combined Modality Therapy; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Proteoglycans; Radiotherapy Dosage; Remission Induction; Tegafur; Uracil; Vitamin A

1988
Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy.
    Acta neurochirurgica, 1988, Volume: 93, Issue:3-4

    Topics: Adolescent; Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Tegafur; Tomography, Emission-Computed

1988
[Response to antitumor agents of human transplantable glioma implanted into chorioallantoic membrane of chick embryo].
    No shinkei geka. Neurological surgery, 1988, Volume: 16, Issue:4

    Topics: Allantois; Animals; Antineoplastic Agents; Brain Neoplasms; Chick Embryo; Chorion; Drug Screening Assays, Antitumor; Extraembryonic Membranes; Glioma; Humans; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds

1988
[Intra-arterial ACNU chemotherapy of malignant glioma].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1988, Feb-25, Volume: 48, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Child; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Nimustine; Nitrosourea Compounds

1988
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Cells, Cultured

1988
In vitro damage of isolated DNA from two brain tumor cell lines induced by a water-soluble antitumor nitrosourea.
    Acta neurologica Scandinavica, 1988, Volume: 77, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line; DNA Damage; DNA, Neoplasm; Glioma; In Vitro Techniques; Nimustine; Nitrosourea Compounds; Rats; Solubility; Water

1988
[Biological basis for combined radio-chemotherapy in radioresistant tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:13

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Survival; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Neoplasms; Nimustine; Prognosis; Radiation Tolerance

1988
DNA lability induced by nimustine and ramustine in rat glioma cells.
    Journal of neurology, neurosurgery, and psychiatry, 1988, Volume: 51, Issue:11

    Topics: Animals; Antineoplastic Agents; Base Sequence; Brain Neoplasms; Cell Line; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Nimustine; Nitrosourea Compounds; Rats; Tumor Cells, Cultured

1988
[Ring enhancement on CT scan associated with the local ACNU administration therapy following glioblastoma surgery].
    Rinsho hoshasen. Clinical radiography, 1988, Volume: 33, Issue:7

    Topics: Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Female; Glioma; Humans; Neoplasm Recurrence, Local; Nimustine; Radiographic Image Enhancement; Reoperation; Tomography, X-Ray Computed

1988
[Analysis of DNA damage induced by nitrosourea derivatives in rat brain tumor cells using a sequencing procedure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Animals; Antineoplastic Agents; Base Sequence; Brain Neoplasms; DNA Damage; DNA, Neoplasm; DNA, Satellite; Glioma; Nimustine; Nitrosourea Compounds; Rats

1988
[Combination therapy with IFN-beta, ACNU and radiation (IAR) in malignant brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Female; Glioma; Humans; Interferon Type I; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage

1986
[Overcoming of ACNU resistance in a subline of rat glioma in vitro and in vivo by reserpine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Drug Resistance; Drug Synergism; Glioma; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Reserpine

1986
Enhanced effect of reserpine upon growth-inhibitory action of ACNU on ACNU-resistant C6 glioma.
    British journal of cancer, 1986, Volume: 53, Issue:6

    Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine

1986
Combined effect of ACNU and 5-FU on rat glioma cells in spheroids and monolayer cultures.
    International journal of cancer, 1986, Aug-15, Volume: 38, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Fluorouracil; Glioma; Nimustine; Nitrosourea Compounds; Rats

1986
[Mechanism and overcoming of resistance in ACNU-resistant sublines of rat brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Membrane Permeability; Drug Resistance; Glioma; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Verapamil

1986
[Experimental studies on induced hypertension chemotherapy of intracerebral inoculated gliomas in rats].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1986, Volume: 61, Issue:4

    Topics: Angiotensin II; Animals; Antineoplastic Agents; Blood Pressure; Brain Neoplasms; Cerebrovascular Circulation; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats

1986
Resistance of tumor cells to chemotherapy.
    Journal of neurosurgery, 1986, Volume: 65, Issue:4

    Topics: Animals; Cell Line; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats

1986
[The effect of hyperthermia and antitumor drugs on brain tumor cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:10

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line; Cisplatin; Combined Modality Therapy; Glioma; Humans; Hyperthermia, Induced; Naphthacenes; Nimustine; Nitrosourea Compounds; Rats

1986
[Intrathecal ACNU for the treatment of a meningeal gliomatosis model].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Body Weight; Glioma; Male; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1987
Modulation in vitro and in vivo of ACNU resistance in a subline of C6 glioma with reserpine.
    Journal of neurosurgery, 1987, Volume: 66, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Glioma; Male; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine

1987
[Studies on the mechanism of ACNU resistance in sublines of rat C6 glioma and 9L gliosarcoma in vitro].
    No shinkei geka. Neurological surgery, 1986, Volume: 14, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Membrane Permeability; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains

1986
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug Therapy, Combination; Glioma; Male; Nicardipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine; Trifluoperazine; Verapamil

1986
[Intrathecal ACNU against malignant leptomeningeal tumors--toxicity and therapeutic effect in experimental animals].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:11

    Topics: Animals; Antineoplastic Agents; Arachnoid; Glioma; Meningeal Neoplasms; Nimustine; Nitrosourea Compounds; Pia Mater; Rats; Rats, Inbred Strains

1986
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Humans; Mechlorethamine; Methylation; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange

1987
Influence of modes of ACNU administration on tissue and blood drug concentration in malignant brain tumors.
    Journal of neurosurgery, 1987, Volume: 66, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Squamous Cell; Female; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Lymphoma; Male; Meningioma; Middle Aged; Nimustine; Nitrosourea Compounds

1987
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Humans; Mechlorethamine; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Stem Cell Assay

1987
Significance of DNA cross-links on 1-(4-amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3- nitrosourea (ACNU)-induced cytotoxicity against ACNU-sensitive and -resistant lines of 9L rat glioma cells.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344

1987
[Overcoming of ACNU resistance in an ACNU-resistant subline of rat C6 glioma in vivo through enhanced effect of ACNU by calmodulin inhibitor].
    No shinkei geka. Neurological surgery, 1987, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Calmodulin; Drug Resistance; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Trifluoperazine

1987
Cell cycle perturbation of cultured C6 glioma cells following short-term contact with a low dose of ACNU.
    Cytometry, 1987, Volume: 8, Issue:4

    Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; DNA, Neoplasm; Flow Cytometry; Glioma; Interphase; Kinetics; Mitosis; Nimustine; Nitrosourea Compounds; Rats

1987
Specific induction of ACNU-resistance in V79 Chinese hamster cells and C6 rat glioma cells.
    Journal of neurosurgery, 1987, Volume: 67, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line; Drug Resistance; Glioma; Mutation; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured

1987
Experimental combination chemotherapy of ACNU and 5-FU against cultured glioma model (spheroid) and subcutaneous rat glioma.
    International journal of cancer, 1987, Oct-15, Volume: 40, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colony-Forming Units Assay; Disease Models, Animal; Fluorouracil; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Time Factors

1987
The mechanism and overcoming of resistance in ACNU-resistant sublines of C6 and 9L rat glioma.
    Journal of neuro-oncology, 1987, Volume: 5, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Membrane Permeability; Dinitrophenols; Drug Resistance; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains; Reserpine

1987
[Experimental studies on the treatment of recurrent gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:6 Pt 1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Glioma; Humans; Immunization, Passive; Interleukin-2; Killer Cells, Natural; Nimustine; Nitrosourea Compounds

1987
[Combination therapy with HU IFN-beta and ACNU against malignant brain tumors, Part 1. Experimental study in vitro].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cells, Cultured; Drug Synergism; Flow Cytometry; Glioma; Humans; Interferon Type I; Nimustine; Nitrosourea Compounds

1985
[Regional blood flow of experimental brain tumors with special reference to effects of chemotherapy and radiotherapy].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Capillary Permeability; Disease Models, Animal; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Regional Blood Flow; Tumor Stem Cell Assay

1985
ACNU-resistant mutants of 9L rat glioma cell line. Isolation and preliminary characterization of these subclones.
    Journal of neurosurgery, 1985, Volume: 63, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line; Drug Resistance; Glioma; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344

1985
[Effects of anticancer drugs on multicellular spheroid of 9L rat brain tumor].
    No to shinkei = Brain and nerve, 1985, Volume: 37, Issue:10

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Glioma; Naphthacenes; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay

1985