nimustine has been researched along with Brain Neoplasms in 296 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 125 (42.23) | 18.7374 |
| 1990's | 88 (29.73) | 18.2507 |
| 2000's | 59 (19.93) | 29.6817 |
| 2010's | 20 (6.76) | 24.3611 |
| 2020's | 4 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A | 1 |
| Bu, XY; Cheng, X; Kong, LF; Luo, JC; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW | 1 |
| Kanamori, M; Okuno, S; Osada, Y; Saigusa, D; Saito, R; Sato, A; Shao, X; Tominaga, T; Uruno, A | 1 |
| Chonan, M; Kanamori, M; Nakasato, N; Osawa, SI; Saito, R; Suzuki, H; Tominaga, T; Watanabe, M | 1 |
| Chen, H; Chen, YJ; Li, YL; Luo, W; Xiang, Q | 1 |
| Hosono, J; Kawamata, T; Komori, T; Maruyama, T; Masui, K; Muragaki, Y; Nitta, M; Saito, T; Yokoo, H | 1 |
| Ikuta, S; Maruyama, T; Muragaki, Y; Nitta, M | 1 |
| Ikuta, S; Muragaki, Y; Shibahara, T | 1 |
| Chen, B; Chen, L; Chen, X; Jiang, T; Li, S; Wang, J; Wang, L; Wang, Y; Wu, C; Zhang, X; Zhang, Z | 1 |
| Chonan, M; Jokura, H; Kanamori, M; Katakura, R; Kato, H; Kawagishi, J; Kawaguchi, T; Kayama, T; Kumabe, T; Mano, Y; Saito, R; Shibahara, I; Sonoda, Y; Tominaga, T; Watanabe, M; Yamashita, Y | 1 |
| Cui, XL; Li, HL; Lin, S; Zhang, JN | 1 |
| Ding, L; Gao, L; Lv, P; Qi, L; Wang, S; Wang, W; Xu, Y; Zhao, D; Zhong, Y | 1 |
| Kikuchi, T; Kumabe, T; Sonoda, Y; Sugiyama, S; Tominaga, T; Yamashita, Y | 1 |
| Eisele, G; Happold, C; Linnebank, M; Roth, P; Steinbach, JP; Weller, M; Wick, W | 1 |
| Heo, DS; Jung, HW; Kim, CY; Kim, DG; Kim, DW; Kim, IH; Lee, SH; Paek, SH; Park, CK; Park, SH | 1 |
| Chernov, M; Hori, T; Iseki, H; Kubo, O; Muragaki, Y; Tajika, Y; Takakura, K | 1 |
| Glas, M; Herrlinger, U; Hundsberger, T; Kurzwelly, D; Nguyen-Huu, B; Rasch, K; Stuplich, M; Wiewrodt, D | 1 |
| Han, JH; Heo, DS; Jung, HW; Kim, CY; Kim, DG; Kim, DW; Kim, IH; Lee, SH; Paek, SH; Park, CK | 1 |
| Christmann, M; Kaina, B; Nikolova, T | 1 |
| Gong, F; Ji, SP; Li, AM; Tai, JL; Zhang, YP; Zheng, CQ | 1 |
| Inoue, T; Kanamori, M; Kumabe, T; Nakazato, Y; Sonoda, Y; Tominaga, T; Watanabe, M | 1 |
| Kochi, M; Kuratsu, J; Makino, K; Nakamura, H; Nakazato, Y | 1 |
| Jung, S; Jung, TY; Kang, SS; Kim, IY; Kim, YH; Lee, KH; Moon, KS; Park, CS | 1 |
| Bertalanffy, H; Bozinov, O; Kalk, JM; Krayenbühl, N; Sure, U; Woernle, CM | 1 |
| Doi, H; Iizuka, H; Ishida-Yamamto, A; Ito, Y; Tsuji, H | 1 |
| Inoue, T; Kanamori, M; Kumabe, T; Sonoda, Y; Tominaga, T; Watanabe, M | 1 |
| Ariga, T; Inoue, O; Iraha, S; Ishiuchi, S; Kakinohana, Y; Kasuya, G; Murayama, S; Ogawa, K; Saito, A; Toita, T; Watanabe, T; Yoshii, Y | 1 |
| Kumabe, T; Nakamura, T; Saito, R; Sonoda, Y; Sugiyama, S; Tominaga, T | 1 |
| Du, H; Hong, Y; Huang, H; Shen, G; Song, J; Wen, X; Xu, G; Yin, Y; Zhang, X | 1 |
| Hamada, J; Hamaguchi, Y; Hayashi, Y; Nakada, M; Shimizu, Y; Sugimori, N; Watanabe, T | 1 |
| Christmann, M; Kaina, B; Meise, R; Tomicic, MT | 1 |
| Guo, Z; Li, J | 1 |
| Fujii, T; Saito, N; Takahashi, K; Tanaka, M; Todo, T; Tsuno, NH | 1 |
| Asai, A; Beppu, T; Fujimaki, T; Fukuda, H; Ito, T; Kayama, T; Kobayashi, H; Kobayashi, K; Kochi, M; Kumabe, T; Kuratsu, J; Maruyama, T; Minamida, Y; Mishima, K; Miyakita, Y; Mizusawa, J; Muragaki, Y; Nagane, M; Nakamura, H; Nakazato, Y; Narita, Y; Nishikawa, R; Nomura, K; Ogasawara, K; Sakurada, K; Sasaki, H; Sato, A; Sawamura, Y; Shibui, S; Sumi, M; Takahashi, H; Takahashi, J; Takano, S; Tanaka, K; Todo, T; Tominaga, T; Wakabayashi, T; Yamaki, T; Yazaki, T | 1 |
| Fujii, K; Hori, T; Kobayashi, I; Nagashima, T; Oka, H; Tanaka, S; Utsuki, S; Watanabe, T | 1 |
| Arai, H; Beppu, T; Fukuda, T; Kamada, K; Nakamura, R; Ogasawara, K; Ogawa, A; Oikawa, H; Takeda, M | 1 |
| Bang, JS; Bang, YJ; Choi, IS; Heo, DS; Jung, HW; Kim, DG; Kim, IH; Kim, NK; Kim, S; Kim, TY; Lee, SH; Paek, SH | 1 |
| Fukumoto, M; Hashimoto, N; Itoh, N; Kono, K; Murai, N; Myoumoto, A; Takahashi, JA; Ueba, T | 1 |
| Bamberg, M; Koch, R; Krauseneck, P; Müller, B; Weller, M | 1 |
| Asai, J; Chang, CW; Fujimoto, T; Nagashima, G; Suzuki, R | 1 |
| Kamiryo, T; Kochi, M; Shinojima, N; Shiraishi, S; Tada, K; Ushio, Y | 1 |
| Shibui, S | 3 |
| Zhang, YP | 1 |
| Fukushima, T; Katayama, Y; Komine, C; Ogino, A; Ohta, T; Watanabe, T; Yoshino, A | 1 |
| Mineta, T; Nakahara, Y; Okamoto, H; Shiraishi, T; Tabuchi, K; Ueda, S | 1 |
| Higuchi, Y; Iwadate, Y; Yamaura, A | 1 |
| Baba, K; Fukami, T; Matsuda, M; Nakasu, S | 1 |
| Boiardi, A; Botturi, A; Broggi, G; Di Meco, F; Eoli, M; Lamperti, E; Salmaggi, A; Silvani, A; Solari, A | 1 |
| Bratengeier, K; Flentje, M; Kölbl, O; Ruprecht, K; Vince, GH; Vordermark, D | 1 |
| Gwak, HS; Kim, JH; Kwon, AH; Lee, SH; Rhee, CH; Youn, SM | 1 |
| Takahashi, H; Tanaka, R | 1 |
| Weller, M | 1 |
| Fujii, K; Kobayashi, I; Oka, H; Tanaka, S; Utsuki, S; Yasui, Y | 1 |
| Kraemer, HP; Schönmayr, R; Tonn, JC | 2 |
| Ido, K; Kubota, T; Matsuda, K; Nakagawa, T; Sakuma, T | 2 |
| Natsume, A; Wakabayashi, T; Yoshida, J | 1 |
| Abe, T; Miyagi, N; Ogo, E; Shigemori, M; Terasaki, M | 1 |
| Adachi, G; Hyodo, A; Inoue, O; Iraha, S; Kakinohana, Y; Murayama, S; Ogawa, K; Saito, A; Sugimoto, K; Tamaki, W; Toita, T; Yoshii, Y | 1 |
| Aoki, T; Fukui, T; Hashimoto, N; Hiraoka, M; Ishikawa, M; Matsui, K; Nakashima, Y; Oya, N; Takahashi, JA; Ueba, T | 1 |
| Kikuchi, T; Kumabe, T; Saito, R; Sugiyama, S; Tominaga, T; Yamashita, Y | 1 |
| Flentje, M; Kölbl, O; Rieckmann, P; Roggendorf, W; Ruprecht, K; Vince, GH; Vordermark, D; Warmuth-Metz, M | 1 |
| Fukaya, R; Hirose, Y; Ikeda, E; Kawase, T; Takahashi, S | 1 |
| Hasegawa, A; Kamada, T; Mizoe, JE; Takagi, R; Takakura, K; Tsuji, H; Tsujii, H; Yanagi, T | 1 |
| Kakuto, Y; Katakura, R; Kumabe, T; Matsumoto, K; Nishino, Y; Sonoda, Y; Tominaga, T | 1 |
| Kumabe, T; Nemoto, K; Nomiya, T; Takai, Y; Yamada, S | 1 |
| Berrak, S; Koontz Webb, SE; Wolff, JE; Zhang, M | 1 |
| Adler, JR; Jackson, PS; Lipani, JD; Sato, K; Soltys, SG | 1 |
| Arai, H; Konno, K; Murakami, N; Suzuki, Y; Takeda, N; Tanaka, R; Tanimura, K | 1 |
| Suzuki, Y; Tanaka, R | 1 |
| Abe, H; Aida, T; Kaneko, S; Kobayashi, H; Kodama, T; Tsuru, M | 1 |
| Harada, K; Kiya, K; Okamoto, H; Uozumi, T | 1 |
| Kageyama, N; Kida, Y; Kobayashi, T; Shibuya, N; Yoshida, J | 1 |
| Kuninaka, A; Machida, H; Nakamura, O; Takakura, K; Takezawa, J; Yoshino, H | 1 |
| Nomura, K; Shibui, S; Watanabe, T | 1 |
| Asari, S; Doi, A; Fujiwara, T; Furuta, T; Matsumoto, K; Moriya, Y; Nakasone, S; Nishimoto, A; Ohnishi, R; Tabuchi, K | 1 |
| Allen, NJ; Clendenon, NR; Kaneko, S; Kartha, M | 1 |
| Kageyama, N; Kobayashi, T; Yoshida, J | 1 |
| Niitani, H; Saijo, N | 1 |
| Harada, K; Kiya, K; Uosumi, T | 1 |
| Kohno, T; Shitara, N; Takakura, K | 1 |
| Kageyama, N; Kobayashi, T; Shibuya, N; Yoshida, J | 2 |
| Kobayashi, T | 2 |
| Saito, Y | 1 |
| Miki, Y; Nakamura, O; Nomura, K; Ohira, M; Shibui, S; Takakura, K; Watanabe, T | 1 |
| Goya, N; Hara, T; Ikeda, K; Inaba, K; Ishii, E; Miyazaki, S; Yoshida, N | 1 |
| Handa, H; Teraura, T; Yamashita, J; Yumitori, K | 2 |
| Honma, T; Min, KY; Nakagawa, H; Yoneda, S; Yoshida, S | 1 |
| Ha, YS; Handa, H; Otsuka, SI; Suda, K; Taki, W; Tokuriki, Y; Yamashita, J | 1 |
| Hokama, Y; Hori, T; Muraoka, K; Numata, H; Saito, Y; Takami, M | 1 |
| Kohono, T; Matsutani, M; Nagashima, T | 1 |
| Iwasa, H; Kohno, T; Matsutani, M; Satoh, F; Takakura, K; Yamamoto, H | 1 |
| Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T | 2 |
| Muraoka, K | 1 |
| Abe, H; Aida, T; Iwakuma, T; Kaneko, S; Kashiwaba, T; Kitaoka, K; Sato, M; Tokuda, K; Tsuru, M; Ueno, K | 1 |
| Ishiwata, Y; Kuwabara, T; Kyuma, Y; Murai, M; Nishimura, S; Shinonaga, M; Yamashita, T | 1 |
| Inoue, I; Kageyama, N; Kanzaki, M; Nagata, M; Wakabayashi, T; Yoshida, J | 1 |
| Akanuma, A; Kohno, T; Maehara, T; Nakamura, O; Sano, K; Sato, F; Shitara, N; Takakura, K; Yamamoto, H | 1 |
| Nakamura, O; Nomura, K; Shibui, S; Watanabe, T | 1 |
| Tanaka, R | 1 |
| Katakura, R; Mineura, K; Mori, T; Sasaki, T | 1 |
| Ito, H; Ohsumi, A; Ohta, Y; Ohyashiki, J; Ohyasiki, K; Osamura, S; Tomita, T; Umehara, S; Yunokawa, K | 1 |
| Hokama, Y; Hori, T; Muraoka, K; Saito, Y; Takami, M | 1 |
| Asai, A; Hayashi, M; Imagawa, K; Kawasaki, M; Nomura, T; Toda, I | 1 |
| Chiba, M; Homma, K; Jimbow, K; Kizukuri, K | 1 |
| Imahori, T; Kasai, H; Kawamoto, K; Numa, Y; Tsuchida, T | 1 |
| Kreth, FW; Ostertag, CB; Warnke, PC | 1 |
| Felix, R; Golde, G; Gremmler, M; Löffel, J; Maier-Hauff, K; Mischel, M; Seebass, M; Stahl, H; Wust, P | 1 |
| Akai, F; Ioku, M; Iwasaki, H; Kaetsu, I; Kuroda, R; Nakatani, J; Uchiyama, T | 1 |
| Hyodo, A; Nose, T; Takada, K; Tsuboi, K; Yoshii, Y | 1 |
| Andoh, T; Hara, A; Murakawa, T; Niikawa, S; Sakai, N; Yamada, H; Zhang, W | 1 |
| Chen, KT; Hau, DM; Pan, HC; Wong, RW; You, JS | 1 |
| Asai, A; Fujimaki, T; Matsutani, M; Nagashima, T; Nakamura, M; Nakamura, O; Tanaka, H; Tanaka, Y; Ueki, K | 1 |
| Izumi, I; Kowada, M; Mineura, K; Watanabe, K | 3 |
| Ikenaga, M; Izumi, I; Kohda, K; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Fujita, H; Hotta, T; Ikenaga, M; Ishizaki, K; Isowa, G; Kiya, K; Kurisu, K; Mikami, T; Saito, Y; Uozumi, T | 1 |
| Kihara, S; Nakagawa, S; Shiraishi, T; Tabuchi, K | 1 |
| Kajita, Y; Sugita, K; Wakabayashi, T; Yoshida, J | 1 |
| Cazzaniga, S; Charles, HC; Schold, SC; Sostman, HD | 1 |
| Kuratsu, J; Ushio, Y | 1 |
| Kayama, T; Kumabe, T; Mizoi, K; Yoshimoto, T | 1 |
| Ikenaga, M; Izumi, I; Kohda, K; Kowada, M; Koyama, K; Mineura, K; Terashima, I; Watanabe, K | 1 |
| Izumu, I; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Kikuchi, H; Moritake, K; Paine, JT; Shima, N; Yamabe, H; Yamasaki, T | 1 |
| Kochi, M; Kuratsu, J; Mihara, Y; Seto, H; Takaki, S; Uemura, S; Ushio, Y | 1 |
| Iwadate, Y; Namba, H; Saegusa, T; Sueyoshi, K | 2 |
| Nemoto, S | 1 |
| Akita, S; Aoki, S; Fujii, H; Kawakami, R; Kosuda, S; Kusano, S; Mezaki, T; Nakamura, O; Shidara, N; Suzuki, K | 1 |
| Shoin, K; Soma, M; Yamashita, J | 1 |
| Ishikawa, H; Kato, T; Kobayashi, M; Kowada, M; Seino, Y; Shindo, M; Tomura, N; Watarai, J | 1 |
| Chiba, Y; Hayashi, A; Kojima, Y; Kuwana, N; Kyuma, Y | 1 |
| Krossnes, BK; Schem, BC | 1 |
| Fujiwara, S; Fukui, M; Inamura, T; Morioka, T; Nishio, S; Shono, T; Takeshita, I | 1 |
| Kawamoto, K | 1 |
| Hatakeyama, T; Kumon, Y; Nakagawa, K; Ohta, S; Sakaki, S; Zenke, K | 1 |
| Amemiya, Y; Hatake, K; Miura, Y; Miyata, T; Muroi, K; Saito, M | 1 |
| Fukuchi, M; Kohda, K; Kowada, M; Mineura, K; Terashima, I | 1 |
| Aoyagi, M; Hirakawa, K; Ichimura, K; Nagashima, G; Niimi, Y; Ohno, K; Tamaki, M | 1 |
| Diete, S; Dietzmann, K; Kirches, E; von Bossanyi, P; Warich-Kirches, M | 1 |
| Marchenko, SV | 1 |
| Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Tsunoda, S; Tsuzuki, T; Yabuno, T | 1 |
| Damian, MS; Leweke, F; Schachenmayr, W; Schindler, C | 1 |
| Flores, LG; Futami, S; Jinnouchi, S; Kawano, H; Kodama, T; Nagamachi, S; Nakahara, H; Ohnishi, T; Tamura, S; Wakisaka, S; Watanabe, K; Yokogami, K | 1 |
| Hirano, Y; Mineura, K; Mizoi, K; Tomura, N | 1 |
| Iseki, H; Kubo, O; Muragaki, Y; Takakura, K | 1 |
| Abe, T; Fujiki, M; Hori, S; Kaku, T; Kawashima, H; Konisi, Y; Mori, T; Morikawa, N; Takeyama, M | 1 |
| Asai, A; Kirino, T; Kuchino, Y; Narita, Y | 1 |
| Asai, A; Kuchino, Y; Nagane, M; Nomura, K; Oyama, H; Shibui, S | 1 |
| Kohda, K; Mineura, K; Takahashi, M; Watanabe, K | 1 |
| Ghulam Muhammad, AK; Isaka, T; Maruno, M; Nakagawa, H; Nakata, H; Ninomiya, H; Yoshimine, T | 1 |
| Amin, MR; Fujii, K; Hori, T; Kamitani, H; Nagashima, T; Oka, H; Tanaka, S; Watanabe, T | 1 |
| Kubo, O; Takakura, K | 1 |
| Hatano, N; Kajita, Y; Nagasaka, T; Thompson, T; Wakabayashi, T; Yoshida, J | 1 |
| Kohshi, K | 1 |
| Anders, K; Fahlbusch, R; Fietkau, R; Grabenbauer, GG; Krauseneck, P; Sauer, R; Schuchardt, U | 1 |
| Deininger, MH; Grote, E; Meyermann, R; Wickboldt, J | 1 |
| Goto, T; Iwasaki, T; Kimura, T; Kino, T; Kitamura, I; Kochii, M; Kuratsu, J; Nishi, T; Saito, Y; Shiraishi, S; Tada, K; Takeshima, H; Uemura, S; Ushio, Y; Yamamoto, K | 1 |
| Abe, T; Hikawa, T; Hori, S; Mori, T | 1 |
| Mima, T; Mori, K; Mostafa, MG | 1 |
| Abe, T; Kawashima, H; Kobayashi, H; Mori, T; Morikawa, N; Takeyama, M | 1 |
| Kajita, Y; Mizuno, M; Wakabayashi, T; Yoshida, J | 1 |
| Kito, A; Mizuno, M; Sugita, K; Wakabayashi, T; Yoshida, J | 1 |
| Fujiwara, T; Honma, Y; Matsumoto, Y; Mino, S; Nagao, S; Tsuchida, T | 1 |
| Akatsuka, K; Hokama, Y; Hori, T; Numata, H; Tabuchi, S; Takigawa, H; Tanaka, S; Watanabe, K | 1 |
| Hoshi, A; Kakuto, Y; Kayama, T; Nemoto, K; Ogawa, Y; Sakamoto, K; Takai, Y; Yamada, S; Yoshimoto, T | 1 |
| Ishiyama, Y; Kowada, M; Mineura, K | 2 |
| Fujiwara, T; Matsumoto, Y; Nagao, S; Sasaoka, N; Tsuchida, T | 1 |
| Niikawa, S; Nozawa, Y; Sakai, N; Yamada, H; Zhang, W | 1 |
| Hyodo, A; Kobayashi, E; Komatsu, Y; Nose, T; Yamada, T; Yoshii, Y | 1 |
| Nagane, M; Nomura, K; Shibui, S | 1 |
| Kan, S; Miyasaka, Y; Murata, K; Ohbu, M; Saito, M; Takagi, H; Takano, S; Yada, K | 1 |
| Beuls, E; Koulousakis, A; Shimizu, K; Sturm, V; Yoshida, TK | 1 |
| Asai, A; Kuchino, Y; Matsutani, M; Nagane, M; Nomura, K; Shibui, S | 1 |
| Darling, JL; Hoffmann, O; Kraemer, HP; Nikkhah, G; Schachenmayr, W; Schönmayr, R; Tonn, JC | 1 |
| Fujita, T; Furuta, Y; Murasawa, A; Nakagawa, H; Nakajima, S; Nakamura, H; Niiyama, K; Shibata, H; Taki, T; Tsuruzono, K | 1 |
| Kagawa, Y; Miyagami, M; Tazoe, M; Tsubokawa, T | 1 |
| Daita, G; Fujita, T; Hodozuka, A; Okazaki, S; Sako, K; Takei, H; Yonemasu, Y | 1 |
| Kawamoto, K; Matsumura, H; Numa, Y | 1 |
| Hanakita, J; Iihara, K; Nishi, S; Nishihara, K; Ohta, F; Sakaida, H; Suwa, H | 1 |
| Andoh, T; Hirata, T; Miwa, Y; Nishimura, Y; Sakai, N; Shimizu, K; Yamada, H; Yanagawa, S | 1 |
| Fujiwara, T; Ohmoto, T; Yoshioka, J | 1 |
| Hirao, J; Hori, T; Muraoka, K; Nakajima, E; Nishiyama, M; Okamoto, H; Tabuchi, F; Tanaka, S; Tatsuhara, T | 1 |
| Apfel, R; Behl, C; Bogdahn, U; Drenkard, D; Lutz, M | 1 |
| Roosen, K; Schachenmayr, W; Tonn, JC | 1 |
| Dahl, O; Schem, BC | 1 |
| Hayakawa, T; Mabuchi, E; Mogami, H; Moriuchi, S; Park, K; Shimizu, K; Tamura, K; Yamada, M | 1 |
| Arita, N; Bitoh, S; Hasegawa, H; Hayakawa, T; Ikeda, H; Kanai, N; Kanoh, M; Mogami, H; Oku, Y; Ushio, Y | 1 |
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Fujita, H; Higano, S; Inugami, A; Kanno, I; Kato, T; Murakami, M; Ogawa, T; Shishido, F; Tomura, N; Uemura, K | 1 |
| Miyagami, M; Tsubokawa, T | 1 |
| Abe, H; Aida, T; Ikoda, T; Itoh, T; Kaneko, S; Kashiwaba, T; Kawamoto, T; Sugimoto, S; Tokuda, K; Ueno, K | 1 |
| Chiba, Y; Fujitsu, K; Hayashi, A; Kuwabara, T; Kyuma, Y; Oda, M; Sekido, K; Shinonaga, M; Yamaguchi, K; Yamashita, T | 1 |
| Sasaoka, N | 1 |
| Yoshii, Y | 1 |
| Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Shimomura, T; Tsunoda, S; Watabe, Y | 1 |
| Heuser, K | 1 |
| Chikama, M; Kawakami, Y; Shimamura, Y; Tanimoto, T; Tsutsumi, A | 1 |
| Miyamachi, K | 1 |
| Shoin, K; Yamashima, T; Yamashita, J | 1 |
| Abe, H; Aida, T; Kaneko, S; Sugimoto, S; Tokuda, K | 1 |
| Amemiya, Y; Kida, Y; Kobayashi, T; Matsui, M | 1 |
| Fushimi, S; Ikenaga, M; Ishizaki, K; Isowa, G; Kowada, M; Mineura, K | 1 |
| Maruo, K; Nakamura, O; Nomura, K; Takakura, K; Ueyama, Y | 2 |
| Cravioto, H; Kida, Y | 1 |
| Mori, K; Moriyama, T; Moroki, J; Shibata, S; Tanaka, K | 2 |
| Handa, Y; Hayashi, M; Ishikura, A; Itoh, H; Kabuto, M; Kawano, H; Kobayashi, H; Kubota, T; Yamamoto, S; Yamashima, T | 1 |
| Akagi, K; Kawakami, K; Kawamoto, K; Kawamura, Y; Matsumura, H; Numa, Y; Ohyama, A; Oka, N | 1 |
| Ito, T; Kawakami, K; Kawamoto, K; Kawamura, Y; Matsumura, H; Ohyama, A; Oka, N | 1 |
| Kageyama, N; Kida, Y; Kobayashi, T; Shibuya, N; Tanaka, T | 1 |
| Matsuoka, K; Nakamura, O; Nomura, K; Shibui, S; Takakura, K; Watanabe, T | 1 |
| Aida, T; Bodell, WJ | 3 |
| Murakami, N; Onda, K; Suzuki, Y; Tanaka, R; Yamazaki, K | 1 |
| Handa, H; Hori, R; Iwakawa, S; Okumura, K; Okumura, T; Tokuriki, Y; Tsukamoto, T; Yamashita, J | 1 |
| Fields, WS; Iwata, K; Yung, WK | 1 |
| Hondo, H; Sato, I; Suzuki, Y; Takeda, N; Tanaka, R | 1 |
| Hattori, K; Kobayashi, T; Takahashi, T; Tanaka, T | 1 |
| Ishida, Y; Nakatsukasa, M; Ogawa, Y; Otani, M; Toya, S; Yoshida, K | 1 |
| Katakura, R; Kitahara, M; Mashiyama, S; Sasaki, T; Suzuki, J; Takahashi, K | 1 |
| Kasahara, E; Miyagami, M; Tazoe, M; Tsubokawa, T | 1 |
| Hosoya, T; Nakai, O; Takahama, H; Takanashi, T; Yamada, K | 1 |
| Kowada, M; Mineura, K; Ogawa, T; Sasajima, T; Shishido, F; Suda, Y; Uemura, K | 1 |
| Fukamachi, A; Kimurat, R; Naganuma, H; Nukui, H; Sasaki, A; Tasaka, K | 1 |
| Bock, WJ; Kiwit, JC; Lins, E; Roosen, N; Schirmer, M | 2 |
| Bock, WJ; Feinendegen, LE; Herzog, H; Kiwit, JC; Kuwert, T; Langen, KJ; Muzik, O; Roosen, N; Rota Kops, E | 1 |
| Fushimi, S; Ishino, Y; Itoh, Y; Kowada, M; Mineura, K | 1 |
| Fushimi, S; Ishino, Y; Kowada, M; Mineura, K; Sasajima, H; Sasaki, J | 3 |
| Hayashi, M; Ishii, H; Ishii, Y; Kawano, H; Nakatsugawa, S; Satoh, K | 1 |
| Nagashima, T; Takakura, K | 1 |
| Mabuchi, E; Matsui, Y; Mogami, H; Moriuchi, S; Park, K; Shimizu, K; Tamura, K; Yamada, M | 1 |
| Furuta, Y; Murasawa, A; Nakagawa, H; Nakajima, S; Nakajima, Y | 1 |
| Kageyama, N; Kito, A; Yoshida, J | 1 |
| Furuta, Y; Masaoka, T; Murasawa, A; Nakagawa, H; Nakajima, S; Nakamura, H; Niiyama, K; Shibata, H; Taki, T | 1 |
| Koga, K; Nishikawa, K; Wakisaka, S; Watanabe, K | 1 |
| Kato, T; Ota, K | 1 |
| Kagawa, Y; Miyagami, M; Tsubokawa, T | 1 |
| Abe, H; Kitamura, K; Matsutani, M; Miwa, T; Nomura, K; Suzuki, J; Takakura, K; Takeuchi, K; Tanaka, R; Ushio, Y | 1 |
| Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M | 1 |
| Ishizaki, R; Matsutani, M; Nakamura, O; Nomura, K; Shitara, N; Takakura, K | 1 |
| Jaksche, H; Loew, F; Papavero, L | 1 |
| Namiki, T; Ogawa, A; Shingai, J; Suzuki, J; Wada, T | 1 |
| Kanno, M; Katakura, R; Kitahara, M; Mori, T; Niizuma, H; Suzuki, J; Wada, T; Yoshimoto, T | 1 |
| Katakura, R; Kitahara, M; Mori, T; Niizuma, H; Shingai, J; Suzuki, J; Wada, T; Yoshimoto, T | 1 |
| Goya, T; Kaji, Y; Kinoshita, K; Kodama, T; Maruoka, N; Moriyama, T; Nonaka, A; Oyama, H; Shimauchi, M; Wakisaka, S | 1 |
| Kowada, M; Mineura, K; Ogawa, T; Shishido, F; Suda, Y; Uemura, K; Yasuda, T | 1 |
| Hioki, K; Hiramatsu, Y; Kojima, Y; Nakane, Y; Sanada, T; Watanabe, T; Yamamoto, M; Yamamura, M | 1 |
| Kawakami, K; Kawamoto, K; Kawamura, Y; Matsumura, H; Miki, K; Nishimura, T; Oka, N; Okuyama, T; Ouchi, M | 1 |
| Endo, Y; Matsutani, M; Nakamura, O; Nishikawa, K; Sasaki, T; Takakura, K; Tanaka, M; Uchida, H | 1 |
| Hirabuki, N; Kawai, R; Kozuka, T; Mitomo, M; Miura, T; Murayama, S; Usio, Y | 1 |
| Aida, T | 1 |
| Fushimi, S; Itoh, Y; Kowada, M; Mineura, K | 2 |
| Kanno, S; Kitahara, M; Kuwahara, K; Mashiyama, S; Sasaki, T; Sugiyama, S; Takahashi, K | 1 |
| Arita, N; Hayakawa, T; Izumoto, S; Mogami, H; Nagatani, M; Oku, Y; Tzuu-Yuan, H; Ushio, Y; Yoshimine, T | 1 |
| Enkaku, F; Ito, H; Shoin, K; Yamamoto, S; Yamashima, T | 1 |
| Niitani, H | 1 |
| Abe, H; Doi, S; Murai, H; Sawamura, Y; Tashiro, K | 1 |
| Abe, H; Handa, H; Kageyama, N; Kitamura, K; Miwa, T; Mogami, H; Takakura, K; Takeuchi, K; Tanaka, R; Yamamoto, S | 1 |
| Enomoto, H; Kageyama, N; Kato, K; Kito, A; Wakabayashi, T; Yoshida, J | 1 |
| Konishi, Y; Nagano, Y; Nakamoto, K; Ohara, H; Terai, T; Tokunaga, Y; Yamauchi, Y | 1 |
| Hayakawa, T; Kato, A; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T | 2 |
| Tokuda, K | 1 |
| Kageyama, N; Kida, Y; Kobayashi, T; Tanaka, T | 1 |
| Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T | 2 |
| Adachi, S; Anno, Y; Hori, T; Inagaki, H; Inoue, Y; Muraoka, K; Saito, Y; Sasahara, K | 1 |
| Arita, N; Hayakawa, T; Huang, TY; Mogami, H; Nagatani, M; Ushio, Y; Yamada, K; Yamada, N | 1 |
| Egawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Yoshida, T | 1 |
| Egawa, T; Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Yoshida, T | 1 |
| Iryo, O; Katayama, M; Kobayashi, S; Kuramoto, S; Miyagi, J; Ootsubo, M; Shigemori, M; Sugita, Y; Uegaki, M | 1 |
| Matsui, Y; Miyao, Y; Mogami, H; Okamoto, Y; Shimizu, K; Tsuda, N; Yamada, M | 1 |
| Inoue, I; Kageyama, N; Wakabayashi, T; Yoshida, J | 1 |
| Asari, S; Kawakami, Y; Nishimoto, A; Ohnishi, R; Tabuchi, K | 1 |
| Aida, T; Bodell, WJ; Rasmussen, J | 1 |
| Matsutani, M; Nagashima, T; Orii, H; Tamura, A | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 1 |
| Hoshino, T; Kohno, T; Matsutani, M; Takakura, K | 1 |
| Nakasu, S; Saito, A; Suda, K | 1 |
13 review(s) available for nimustine and Brain Neoplasms
| Article | Year |
|---|---|
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Cisplatin; Dacarbazine; Disease-Free Survival; Eflornithine; Glioma; Humans; Mitolactol; Network Meta-Analysis; Nimustine; Probability; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide; Treatment Outcome; Vincristine | 2016 |
[Study on MGMT assay and tumor individual predictable chemotherapy].
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Resistance, Neoplasm; HeLa Cells; Humans; Mice; Mice, Nude; Neoplasms; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Reagent Kits, Diagnostic; RNA, Messenger | 2004 |
[Resent advances in chemotherapy for malignant brain tumors].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Humans; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Procarbazine; Quality Control; Randomized Controlled Trials as Topic | 2005 |
[Chemotherapy for brain tumor].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Delivery Systems; Etoposide; Humans; Lymphoma; Medulloblastoma; Methotrexate; Neoplasms, Germ Cell and Embryonal; Nimustine; Oligodendroglioma; Platinum Compounds; Randomized Controlled Trials as Topic; Vincristine | 2005 |
[Standards and new developments in the chemotherapy of glioblastomas].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Cytarabine; Dacarbazine; Decanoic Acids; DNA Modification Methylases; Glioblastoma; Humans; Nimustine; Polyesters; Promoter Regions, Genetic; Temozolomide; Teniposide | 2005 |
[Treatment for malignant glioma].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Glioma; Humans; Nimustine | 2005 |
[Glioma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Drug Synergism; Genetic Therapy; Glioma; Humans; Interferon-beta; Nimustine; Radiotherapy; Temozolomide | 2006 |
[Hyperthermic treatment of malignant tumors. Possible application to the treatment of brain tumors].
Topics: Animals; Brain Neoplasms; Cobalt Radioisotopes; Culture Techniques; Electrocoagulation; Glioma; Haplorhini; Hot Temperature; Humans; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats; Sarcoma, Experimental | 1982 |
[Chemotherapy of brain tumors].
Topics: Blood-Brain Barrier; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Glioma; Humans; Nimustine | 1994 |
[Malignant brain tumor treatment and hyperbaric oxygenation].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Glioma; Humans; Hyperbaric Oxygenation; Nimustine | 2000 |
[Chemical modifiers in radiotherapy].
Topics: Brain Neoplasms; Bromodeoxyuridine; Combined Modality Therapy; Glioma; Humans; Immunologic Factors; Interferon Type I; Nimustine; Radiation-Sensitizing Agents | 1989 |
[Advances on ACNU in the past 10 years].
Topics: Antineoplastic Agents; Brain Neoplasms; Humans; Lung Neoplasms; Neoplasms; Nimustine; Nitrosourea Compounds | 1988 |
[An autopsy case of neurocutaneous melanosis associated with intracerebral malignant melanoma].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Humans; Male; Melanoma; Nevus, Pigmented; Nimustine; Nitrosourea Compounds; Skin Neoplasms; Vincristine | 1987 |
34 trial(s) available for nimustine and Brain Neoplasms
| Article | Year |
|---|---|
Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma.
Topics: Brain Neoplasms; Glioblastoma; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Macrophage Colony-Stimulating Factor; Neutropenia; Nimustine; Temozolomide; Thrombocytopenia | 2023 |
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Postoperative Complications; Temozolomide; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult | 2014 |
Phase II trial of radiotherapy after hyperbaric oxygenation with multiagent chemotherapy (procarbazine, nimustine, and vincristine) for high-grade gliomas: long-term results.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Follow-Up Studies; Glioblastoma; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Multivariate Analysis; Nimustine; Procarbazine; Radiation Tolerance; Supratentorial Neoplasms; Vincristine; Young Adult | 2012 |
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Immunotherapy, Active; Male; Middle Aged; Nimustine; Temozolomide | 2013 |
Randomized trial of chemoradiotherapy and adjuvant chemotherapy with nimustine (ACNU) versus nimustine plus procarbazine for newly diagnosed anaplastic astrocytoma and glioblastoma (JCOG0305).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Procarbazine | 2013 |
A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Hyperbaric Oxygenation; Interferon-beta; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Middle Aged; Nimustine; Radiotherapy Dosage; Survival Rate | 2003 |
Phase II study of chemotherapy with ACNU plus cisplatin followed by cranial irradiation in patients with newly diagnosed glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Survival Analysis | 2002 |
Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Progression; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Prognosis; Prospective Studies; Survival Analysis; Teniposide; Treatment Outcome | 2003 |
Randomized controlled trial on malignant brain tumors--activities of the Japan Clinical Oncology Group-Brain Tumor Study Group.
Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Nimustine; Procarbazine | 2004 |
Local drug delivery in recurrent malignant gliomas.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Doxorubicin; Drug Delivery Systems; Drug Therapy, Combination; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Survival Rate; Treatment Outcome | 2005 |
Feasibility and response to 1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride chemotherapy with pre-treated procarbazine for elderly patients with newly diagnosed glioblastoma.
Topics: Aged; Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Benzylisoquinolines; Brain Neoplasms; Disease-Free Survival; Feasibility Studies; Female; Glioblastoma; Humans; Male; Middle Aged; Neutropenia; Nimustine; Procarbazine; Survival Analysis; Treatment Outcome; Vincristine | 2007 |
Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nimustine; Procarbazine; Radiotherapy; Survival Analysis; Treatment Outcome; Vincristine | 2006 |
Phase II study of nimustine, carboplatin, vincristine, and interferon-beta with radiotherapy for glioblastoma multiforme: experience of the Kyoto Neuro-Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Drug Tolerance; Female; Glioblastoma; Humans; Interferon-beta; Male; Middle Aged; Nimustine; Vincristine | 2006 |
Phase I/II clinical trial of carbon ion radiotherapy for malignant gliomas: combined X-ray radiotherapy, chemotherapy, and carbon ion radiotherapy.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carbon Radioisotopes; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Radiotherapy Dosage | 2007 |
Prospective single-arm study of 72 Gy hyperfractionated radiation therapy and combination chemotherapy for anaplastic astrocytomas.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Humans; Male; Nimustine | 2008 |
Leukoencephalopathy associated with intra-arterial ACNU in patients with gliomas.
Topics: Adolescent; Adult; Aged; Brain; Brain Diseases; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Infant; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Recurrence; Tomography, X-Ray Computed | 1995 |
Radiation therapy combined with radiosensitizing agents for cerebral glioblastoma in adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Glioblastoma; Humans; Male; Middle Aged; Nicardipine; Nimustine; Radiation-Sensitizing Agents; Survival Analysis; Vincristine | 1994 |
Long-term follow-up results of 175 patients with malignant glioma: importance of radical tumour resection and postoperative adjuvant therapy with interferon, ACNU and radiation.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Female; Follow-Up Studies; Glioblastoma; Humans; Infant; Interferon-beta; Male; Middle Aged; Nimustine; Postoperative Complications; Radiotherapy, Adjuvant; Survival Rate | 1994 |
[Intra-arterial ACNU, CDDP chemotherapy for brain metastases from lung cancer: comparison of cases with and without intra-arterial mannitol infusion].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cisplatin; Female; Humans; Infusions, Intra-Arterial; Lung Neoplasms; Male; Mannitol; Middle Aged; Nimustine; Quality of Life; Survival Rate | 1993 |
Intra-arterial mannitol infusion in the chemotherapy for malignant brain tumors.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Cisplatin; Combined Modality Therapy; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Mannitol; Middle Aged; Nimustine; Survival Rate | 1993 |
Therapeutic results of intra-arterial chemotherapy in patients with malignant glioma.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Male; Middle Aged; Nimustine; Survival Analysis | 1998 |
Pharmacokinetics of nimustine, methotrexate, and cytosine arabinoside during cerebrospinal fluid perfusion chemotherapy in patients with disseminated brain tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Female; Half-Life; Humans; Injections, Intraventricular; Methotrexate; Middle Aged; Nimustine; Perfusion | 1998 |
Preliminary individual adjuvant therapy for gliomas based on the results of molecular biological analyses for drug-resistance genes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Brain Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioma; Humans; Immunohistochemistry; Middle Aged; Multidrug Resistance-Associated Proteins; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prospective Studies; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured | 2000 |
Accelerated radiotherapy with concomitant ACNU/Ara-C for the treatment of malignant glioma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Radiotherapy; Survival Rate | 2000 |
Randomized comparison of intra-arterial versus intravenous infusion of ACNU for newly diagnosed patients with glioblastoma.
Topics: Adolescent; Adult; Aged; Aging; Antineoplastic Agents; Brain Neoplasms; Disease Progression; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Middle Aged; Nimustine; Proportional Hazards Models; Prospective Studies; Survival Analysis | 2000 |
Pharmacokinetics of nimustine, cytosine arabinoside, and methotrexate in cerebrospinal fluid during cerebrospinal fluid perfusion chemotherapy.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cytarabine; Humans; Male; Methotrexate; Nimustine; Perfusion | 2001 |
Intratumoral microinfusion of nimustine (ACNU) for recurrent glioma.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Child; Female; Glioma; Humans; Injections, Intralesional; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Nimustine; Oligodendroglioma; Prospective Studies | 2001 |
Preventive effects of interleukin 1 beta for ACNU-induced myelosuppression in malignant brain tumors: the experimental and preliminary clinical studies.
Topics: Aged; Agranulocytosis; Animals; Brain Neoplasms; Combined Modality Therapy; Drug Screening Assays, Antitumor; Female; Glioblastoma; Humans; Immunologic Factors; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Nimustine; Recombinant Proteins; Remission Induction; Thrombocytopenia; Transplantation, Heterologous; Vincristine | 1992 |
Intraoperative radiation therapy for malignant glioma.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Intraoperative Care; Life Tables; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Survival Rate | 1991 |
Chemotherapy of brain metastases from lung carcinoma: a controlled randomized study.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Carmustine; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nimustine; Radiotherapy Dosage; Remission Induction; Semustine; Survival Rate; Tegafur | 1991 |
[Randomized controlled study on the effect of adjuvant immunotherapy with OK-432 on malignant gliomas].
Topics: Adult; Aged; Antineoplastic Agents; Biological Products; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Picibanil; Random Allocation | 1985 |
[Evaluation of ACNU alone and combined with tegafur as additions to radiotherapy of the treatment of malignant gliomas--a cooperative clinical trial].
Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage; Tegafur | 1985 |
Effects of ACNU and radiotherapy on malignant glioma.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; Glioma; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nimustine; Nitrosourea Compounds | 1986 |
Randomized controlled study of the effect of adjuvant immunotherapy with Picibanil on 51 malignant gliomas.
Topics: Adult; Aged; Biological Products; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Picibanil; Random Allocation; Skin Tests | 1987 |
249 other study(ies) available for nimustine and Brain Neoplasms
| Article | Year |
|---|---|
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glioblastoma; Histones; Humans; Injections, Intraperitoneal; Lomustine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2021 |
Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Delivery Systems; Nimustine; Rats; Rats, Inbred F344; Transforming Growth Factor beta1; Tumor Microenvironment | 2023 |
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Drug Resistance; Drug Resistant Epilepsy; Female; Follow-Up Studies; Glioma; Humans; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Neurosurgical Procedures; Nimustine; Nitriles; Pyridones; Radiotherapy, Adjuvant; Receptors, AMPA; Retrospective Studies; Temozolomide; Young Adult | 2020 |
High dose of nimustine as an add-on treatment for small cell lung cancer with intracranial metastasis: A case report and literature review.
Topics: Aged; Antineoplastic Agents; Antineoplastic Protocols; Brain; Brain Neoplasms; Chemoradiotherapy; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neurologic Examination; Nimustine; Small Cell Lung Carcinoma; Treatment Outcome; Vision Disorders | 2017 |
Role of a Promoter Mutation in TERT in Malignant Transformation of Pleomorphic Xanthoastrocytoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Transformation, Neoplastic; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p15; Cytoreduction Surgical Procedures; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Deletion; Genes, p16; Humans; Mutation; Neoplasm Proteins; Neoplasm Recurrence, Local; Nimustine; Photochemotherapy; Porphyrins; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Radiosurgery; Reoperation; Telomerase; Temporal Lobe | 2019 |
[Nimustine hydrochloride/ranimustine efficacy and safety in glioma].
Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Nimustine; Nitrosourea Compounds | 2016 |
Machine-Learning Approach for Modeling Myelosuppression Attributed to Nimustine Hydrochloride.
Topics: Adult; Antineoplastic Agents; Blood Platelets; Brain Neoplasms; Female; Follow-Up Studies; Humans; Leukopenia; Lymphocytes; Machine Learning; Male; Middle Aged; Models, Statistical; Myelopoiesis; Nimustine; Prognosis | 2018 |
Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Middle Aged; Nimustine; Survival Analysis; Temozolomide; Tumor Suppressor Proteins; Young Adult | 2014 |
Treatment results of glioblastoma during the last 30 years in a single institute.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Hospitals, University; Humans; Japan; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Neuronavigation; Nimustine; Prognosis; Retrospective Studies; Temozolomide; Treatment Outcome | 2013 |
Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Convection; Cranial Irradiation; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Gliosarcoma; Injections, Intraperitoneal; Male; Nimustine; Rats; Rats, Inbred F344; Survival Analysis; Survival Rate; Temozolomide; Treatment Outcome; Xenograft Model Antitumor Assays | 2008 |
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Temozolomide | 2009 |
Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Cisplatin; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Predictive Value of Tests; Promoter Regions, Genetic; Treatment Outcome; Tumor Suppressor Proteins; Young Adult | 2009 |
Coincidence of central neurocytoma and multiple glioblastomas: a rare case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Lineage; Combined Modality Therapy; Cranial Irradiation; Electroencephalography; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Neoplasms, Multiple Primary; Neurocytoma; Neurosurgical Procedures; Nimustine; Tomography, X-Ray Computed; Vincristine | 2009 |
Nimustine (ACNU) plus teniposide (VM26) in recurrent glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Retrospective Studies; Teniposide | 2009 |
Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dacarbazine; Drug Therapy, Combination; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Staging; Nimustine; Retrospective Studies; Salvage Therapy; Survival Analysis; Temozolomide | 2009 |
FEN1 is overexpressed in testis, lung and brain tumors.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Brain Neoplasms; Cisplatin; Dacarbazine; Flap Endonucleases; Flow Cytometry; Humans; Lung Neoplasms; Male; Methyl Methanesulfonate; Nimustine; RNA, Messenger; RNA, Small Interfering; Temozolomide; Testicular Neoplasms | 2009 |
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azacitidine; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Dacarbazine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Survival Rate; Temozolomide; Young Adult | 2009 |
Long-term survivors of glioblastoma: clinical features and molecular analysis.
Topics: Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Protocols; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Male; Middle Aged; Neurosurgical Procedures; Nimustine; Prognosis; Promoter Regions, Genetic; Radiotherapy; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome; Tumor Suppressor Proteins; Young Adult | 2009 |
Successful treatment of neoadjuvant therapy for papillary tumor of the pineal region.
Topics: Brain Neoplasms; Carcinoma, Papillary; Child; Humans; Hydrocephalus; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neoadjuvant Therapy; Neurosurgical Procedures; Nimustine; Pineal Gland; Pinealoma; Treatment Outcome | 2009 |
Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Cisplatin; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Immunohistochemistry; Male; Microsurgery; Middle Aged; Neoplasm Recurrence, Local; Neurosurgical Procedures; Nimustine; Polymerase Chain Reaction; Promoter Regions, Genetic; Radiotherapy, Adjuvant; Reoperation; Temozolomide; Time Factors; Treatment Outcome; Tumor Suppressor Proteins | 2010 |
Decreasing expression of the interleukin-13 receptor IL-13Ralpha2 in treated recurrent malignant gliomas.
Topics: Actins; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Exotoxins; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunotoxins; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Recombinant Fusion Proteins; RNA; Teniposide; Young Adult | 2010 |
Malignant melanoma of the breast: N-isopropyl-p-(123) I-iodoamphetamine single photon emission computed tomography ((123) I-IMP SPECT) is useful for the detection of metastasis.
Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Dacarbazine; Fatal Outcome; Female; Humans; Interferon-beta; Iofetamine; Liver Neoplasms; Lung Neoplasms; MART-1 Antigen; Mastectomy, Modified Radical; Melanoma; Middle Aged; Neoplasm Staging; Nimustine; Nipples; Radiopharmaceuticals; S100 Proteins; Skin Neoplasms; Tamoxifen; Tomography, Emission-Computed, Single-Photon; Vincristine | 2010 |
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fatal Outcome; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasms, Neuroepithelial; Neurosurgical Procedures; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Retrospective Studies; Temozolomide; Tumor Suppressor Protein p53; Young Adult | 2010 |
Local convection-enhanced delivery of chemotherapeutic agent transiently opens blood-brain barrier and improves efficacy of systemic chemotherapy in intracranial xenograft tumor model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Convection; Doxorubicin; Drug Delivery Systems; Gliosarcoma; Kaplan-Meier Estimate; Male; Nimustine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Treatment Outcome; Xenograft Model Antitumor Assays | 2011 |
An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human glioma cells.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Glioma; Humans; Immunohistochemistry; Nimustine; Receptors, Transferrin | 2011 |
Neuro-Sweet disease mimicking recurrent anaplastic astrocytoma associated with therapy-related myelodysplastic syndrome: a case report.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Astrocytoma; Brain; Brain Neoplasms; Carcinoma; Chemoradiotherapy; Drug Eruptions; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Myelodysplastic Syndromes; Nimustine; Sweet Syndrome | 2012 |
The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; DNA Repair; Down-Regulation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Glioma; Humans; Mice; Nimustine; Proto-Oncogene Proteins c-fos; Transcription Factor AP-1 | 2012 |
[Selected arterial infusion chemotherapy combined with target drugs for non-small cell lung cancer with multiple brain metastase].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Carcinoma, Non-Small-Cell Lung; Crown Ethers; Deoxycytidine; Drug Administration Schedule; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gemcitabine; Humans; Infusions, Intra-Arterial; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nimustine; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Skin Diseases; Survival Analysis; Treatment Outcome | 2012 |
O6-methylguanine-DNA methyltranspherase gene expression in gliomas by means of real-time quantitative RT-PCR and clinical response to nitrosoureas.
Topics: Adult; Antineoplastic Agents; beta 2-Microglobulin; Brain Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Middle Aged; Neoplasm Recurrence, Local; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Rate; Transcription, Genetic | 2003 |
In vitro growth suppression of human glioma cells by a 16-mer oligopeptide: a potential new treatment modality for malignant glioma.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cisplatin; Drug Synergism; Etoposide; Fibroblast Growth Factor 2; Glioma; Humans; Nimustine; Oligopeptides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Antisense; Signal Transduction; Tumor Cells, Cultured | 2003 |
[Role of thallium SPECT for evaluating the effect of maintenance chemotherapy against malignant gliomas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Administration Schedule; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon; Vincristine | 2003 |
Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Methylation; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Retrospective Studies | 2004 |
O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course.
Topics: Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Interferon-beta; Male; Middle Aged; Mutation; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Prospective Studies; Radiation Dosage; Radiotherapy, Adjuvant; Survival Rate; Tumor Suppressor Protein p53 | 2005 |
Induction of the DNA repair gene O6-methylguanine-DNA methyltransferase by dexamethasone in glioblastomas.
Topics: Antineoplastic Agents; Antineoplastic Agents, Hormonal; Brain Neoplasms; Dexamethasone; Drug Resistance, Neoplasm; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 2004 |
Treatment of low-grade oligodendroglial tumors without radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Life Tables; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Oligodendroglioma; Procarbazine; Prospective Studies; Survival Analysis; Treatment Outcome; Vincristine | 2004 |
Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Brain; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Immunohistochemistry; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Radiotherapy; Survival Analysis | 2004 |
Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma.
Topics: Antineoplastic Agents; Brain Neoplasms; Disease Progression; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Nimustine; Prognosis; Radiosurgery; Radiotherapy; Recurrence; Stereotaxic Techniques; Teniposide; Time Factors; Treatment Outcome | 2005 |
ACNU-cisplatin continuous infusion chemotherapy as salvage therapy for recurrent glioblastomas: phase II study.
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Clinical Trials, Phase II as Topic; Cohort Studies; Drug Therapy, Combination; Female; Glioblastoma; Humans; In Vitro Techniques; Korea; Magnetic Resonance Imaging; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Survival Analysis; Tomography, X-Ray Computed | 2005 |
Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cisplatin; Down-Regulation; Female; Gene Expression Profiling; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
Resistance of human malignant intracranial tumors in vitro: potential guidelines to clinical therapy?
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Division; Drug Resistance, Neoplasm; Humans; Models, Biological; Nimustine; Tumor Cells, Cultured | 1989 |
Gene expression profiles of 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU)-resistant C6 rat glioma cells.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Profiling; Glioma; Immunohistochemistry; Nimustine; Oligonucleotide Array Sequence Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Safety and efficacy of convection-enhanced delivery of ACNU, a hydrophilic nitrosourea, in intracranial brain tumor models.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Cancer, Regional Perfusion; Convection; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Gliosarcoma; Humans; Male; Maximum Tolerated Dose; Nimustine; Random Allocation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Survival Analysis; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2007 |
Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Craniotomy; Disease Progression; Disease-Free Survival; Female; Glioblastoma; Humans; Life Tables; Male; Middle Aged; Nimustine; Oligodendroglia; Oligodendroglioma; Prognosis; Radiotherapy, Adjuvant; Survival Analysis; Teniposide; Treatment Outcome | 2006 |
The combined effects of multiple chemotherapeutic agents for malignant glioma cells.
Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Etoposide; Glioma; Humans; Models, Statistical; Nimustine; Vincristine | 2007 |
Chromosome arm 1q gain associated with good response to chemotherapy in a malignant glioma. Case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosome Aberrations; Chromosomes, Human, Pair 1; Glioblastoma; Humans; Male; Nimustine; Peplomycin; Treatment Outcome; Vincristine | 2007 |
Primary CNS lymphoma treated with combined intra-arterial ACNU and radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Disease-Free Survival; Female; Humans; Infusions, Intra-Arterial; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Middle Aged; Nimustine; Prognosis; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies | 2007 |
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Cohort Studies; Data Interpretation, Statistical; Databases, Factual; Female; Glioblastoma; Glioma; Humans; Lomustine; Male; Nimustine; Nitrosourea Compounds; Reproducibility of Results; Selection Bias; Survival Analysis; Treatment Outcome | 2008 |
Survival following CyberKnife radiosurgery and hypofractionated radiotherapy for newly diagnosed glioblastoma multiforme.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nimustine; Radiosurgery; Radiotherapy; Retrospective Studies; Vincristine | 2008 |
[Radiotherapy using bleomycin, ACNU, and vincristine for malignant brain tumors. Efficacy for tumor regression].
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bleomycin; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Vincristine | 1984 |
[Anti-tumor effect of ACNU on experimental mouse brain tumors].
Topics: Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Male; Mice; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds | 1980 |
[Experimental study of immunochemotherapy of brain tumors--experimental brain tumor model and immunochemotherapy by a combination of PS-K and ACNU (author's transl)].
Topics: Animals; Basidiomycota; Brain Neoplasms; Drug Therapy, Combination; Immunotherapy; Neoplasm Transplantation; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Proteoglycans; Rats | 1980 |
[Comparative studies on anti-tumor effects of nitrosoureas, ACNU and MCNU, on experimental brain tumors (author's transl)].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Glioma; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds | 1981 |
[Chemotherapy of a rat brain tumor model by innoculation of ascites hepatoma cells--effects of ACNU and adriamycin, and their tissue concentrations (author's transl)].
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cells, Cultured; Disease Models, Animal; Doxorubicin; Liver Neoplasms, Experimental; Male; Nimustine; Nitrosourea Compounds; Rats | 1981 |
Interferon induction and therapy of brain tumors in rats by poly(ICLC).
Topics: Animals; Body Weight; Brain Neoplasms; Carboxymethylcellulose Sodium; Dose-Response Relationship, Drug; Interferons; Male; Methylcellulose; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Peptides; Picibanil; Poly I-C; Polylysine; Rats | 1982 |
[Application of flow cytometry to chemotherapy of malignant brain tumor].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Survival; Cells, Cultured; DNA; Drug Evaluation, Preclinical; Drug Resistance; Flow Cytometry; Humans; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats; Staining and Labeling | 1982 |
[Combination chemotherapy of brain tumors with ACNU and 5-FU].
Topics: Astrocytoma; Biological Products; Brain Neoplasms; Combined Modality Therapy; Drug Therapy, Combination; Ependymoma; Fluorouracil; Glioma; Humans; Lymphoma; Meningeal Neoplasms; Meningioma; Nimustine; Nitrosourea Compounds; Oligodendroglioma; Picibanil | 1983 |
[Treatment schedule of combination using radiation and ACNU in the experimental brain tumors].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; DNA, Neoplasm; Drug Administration Schedule; Glioma; Male; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1983 |
Multimodality treatment of malignant glioma. Effect of chemotherapy with ACNU and immunotherapy with N-CWS.
Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds | 1984 |
Experimental and clinical effect of ACNU in Japan with emphasis on small-cell carcinoma of the lung.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Japan; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats | 1980 |
Pharmacokinetics of a new water-soluble nitrosourea derivative (ACNU) in human gliomas.
Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Glioma; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tissue Distribution | 1981 |
[Adjuvant immunotherapy with levamisole for malignant glioma].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Bromodeoxyuridine; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Glioblastoma; Humans; Levamisole; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Vincristine | 1983 |
[Anti-tumor activity of ACNU against malignant glioma--a clinical application of in vitro sensitivity test of chemotherapeutic agent].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds | 1983 |
[Multidisciplinary treatment of metastatic brain tumor and its fundamental studies for chemo-immunotherapy].
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Humans; Immunity, Cellular; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; T-Lymphocytes | 1984 |
[Long-term survival of patients with brain tumors treated with ACNU and PSK after surgery--with special reference to there immunological follow-up].
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Immunoglobulins; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Postoperative Period; Proteoglycans; T-Lymphocytes | 1984 |
Intensive chemotherapy with autologous bone marrow rescue for recurrent malignant gliomas.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Male; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds | 1984 |
High-dose 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitro sou rea hydrochloride (ACNU) with autologous bone marrow rescue for patients with brain stem tumors.
Topics: Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Combined Modality Therapy; Humans; Kinetics; Nimustine; Nitrosourea Compounds; Prohibitins; Transplantation, Autologous | 1984 |
[Treatment of brain tumor with phenobarbital and continuous infusion of ACNU into internal carotid artery].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carotid Artery, Internal; Drug Therapy, Combination; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital | 1983 |
[Combination chemotherapy of primary adenocarcinoma of the lung using adriamycin, ACNU, and vindesine].
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nimustine; Nitrosourea Compounds; Vinblastine; Vindesine | 1983 |
Intra-arterial ACNU therapy for malignant brain tumors. Experimental studies and preliminary clinical results.
Topics: Adult; Animals; Brain Neoplasms; Cell Line; Female; Glioma; Humans; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intravenous; Male; Mice; Middle Aged; Nimustine; Nitrosourea Compounds; Platelet Count; Radiography; Rats; Rats, Inbred Strains | 1983 |
[Study on postoperative local chemotherapy of malignant brain tumors using ACNU and PSK].
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carotid Arteries; Drug Therapy, Combination; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Postoperative Period; Proteoglycans | 1983 |
[Effects of phenobarbital on the metabolism of ACNU in vivo].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Glioma; Male; Nimustine; Nitrosourea Compounds; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
[Second-look operations and chemotherapy for malignant tumors of the brain].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Reoperation; Teniposide | 1983 |
[Enhanced effect of reserpine on growth-inhibitory action of ACNU on ACNU resistance C6 glioma].
Topics: Animals; Brain Neoplasms; DNA Repair; Drug Resistance; Drug Synergism; Glioma; Growth Inhibitors; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine | 1984 |
[ACNU delivery to malignant tumor tissue and serum--route of administration and combined use of phenobarbital].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain; Brain Neoplasms; Child, Preschool; Drug Therapy, Combination; Ependymoma; Female; Glioma; Humans; Injections, Intra-Arterial; Kinetics; Lymphoma; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital | 1983 |
[Evaluation of radiation immunochemotherapy in the treatment of malignant glioma. Combined use of ACNU, VCR and PS-K].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Glioma; Humans; Middle Aged; Nimustine; Nitrosourea Compounds; Proteoglycans; Vincristine | 1983 |
Treatment of malignant brain tumours with ACNU and phenobarbital: continuous infusion of ACNU into internal carotid artery and systemic administration of phenobarbital.
Topics: Adult; Aged; Astrocytoma; Bone Marrow; Brain Neoplasms; Carotid Artery, Internal; Erythrocyte Count; Female; Glioma; Humans; Infusions, Intra-Arterial; Leukocyte Count; Lymphoma; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Phenobarbital; Tomography, X-Ray Computed | 1984 |
[Chemotherapy for experimental subarachnoid dissemination model of brain tumor].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Injections, Intraperitoneal; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Picibanil; Rats; Rats, Inbred Strains | 1984 |
[MCNU effectiveness on brain tumor. Part I: Antitumor activity in vitro on human glioma and neuroblastoma cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line; Cells, Cultured; DNA, Neoplasm; Flow Cytometry; Glioma; Humans; Mitosis; Neuroblastoma; Nimustine; Nitrosourea Compounds | 1984 |
[Synchronization chemoradiotherapy for malignant gliomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Teniposide; Vincristine | 1984 |
[Flow cytometric study of enhanced effect of anti-cancer drugs induced by nicardipine hydrochloride].
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Glioma; Interphase; Methylnitrosourea; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Vincristine | 1984 |
[Therapeutic effects of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) and radiation on the rat glioma (author's transl)].
Topics: Animals; Brain Neoplasms; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Glioma; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats | 1981 |
Sensitivity to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) of glioma cells in vivo and in vitro.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line; Drug Evaluation, Preclinical; Glioma; Humans; Kinetics; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats | 1982 |
[Two cases of central nervous system leukemia which responded excellently to intra-arterial injection of ACNU].
Topics: Adolescent; Adult; Brain Neoplasms; Humans; Injections, Intra-Arterial; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Nimustine; Nitrosourea Compounds | 1982 |
[Postoperative treatment of malignant brain tumors with ACNU and PSK-particularly immunological follow-up research].
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Therapy, Combination; Female; Humans; Immunoglobulins; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Postoperative Care; Proteoglycans | 1982 |
[Pharmacokinetics of ACNU in cerebrospinal fluid].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Child; Female; Humans; Intracranial Pressure; Kinetics; Male; Middle Aged; Nimustine; Nitrosourea Compounds | 1982 |
Chemoimmunotherapy for disseminated malignant melanoma with DTIC, ACNU, VCR and OK432. Case presentation of two complete and one partial reponse out of fifteen attempts.
Topics: Adjuvants, Immunologic; Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Nimustine; Nitrosourea Compounds; Picibanil; Skin Neoplasms; Vincristine | 1982 |
[Effective measures against side effects by increasing ACNU dose for malignant glioma: effects on digestive organs].
Topics: Adult; Aged; Anorexia; Brain Neoplasms; Drug Therapy, Combination; Female; Glioma; Granisetron; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Nausea; Nimustine; Vomiting | 1994 |
Long-term follow-up results of 175 patients with malignant glioma.
Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Follow-Up Studies; Glioma; Humans; Interferons; Nimustine; Radiotherapy, Adjuvant; Survival Rate; Treatment Outcome | 1994 |
[The use of an early postoperative interstitial-hyperthermia combination therapy in malignant gliomas].
Topics: Antineoplastic Agents; Brachytherapy; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Glioma; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Nimustine; Pilot Projects; Postoperative Care; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Time Factors; Tomography, X-Ray Computed | 1995 |
Interstitial chemotherapy with biodegradable ACNU pellet for glioblastoma.
Topics: Adult; Aged; Animals; Biodegradation, Environmental; Brain Neoplasms; Drug Implants; Female; Glioblastoma; Humans; Lactates; Lactic Acid; Male; Middle Aged; Nimustine; Polyesters; Polymers; Rats; Rats, Wistar | 1994 |
Effect of interferon-gamma on ACNU-induced DNA damage and cytotoxicity in human glioblastoma cells.
Topics: Brain Neoplasms; Cell Line; Cell Survival; DNA Damage; Drug Synergism; Glioma; Humans; Interferon-gamma; Microscopy, Fluorescence; Nimustine; Tumor Cells, Cultured | 1993 |
Therapeutic effects of photosensitizers in combination with laser and ACNU on an in vivo or in vitro model of cerebral glioma.
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Gliosarcoma; Hematoporphyrin Derivative; Humans; Laser Therapy; Male; Neoplasm Transplantation; Nimustine; Photochemotherapy; Rats; Rats, Sprague-Dawley; RNA, Neoplasm; Tumor Cells, Cultured | 1995 |
Enhancement of ACNU cytotoxicity by pretreatment with O6-methylguanine in ACNU-resistant brain tumors.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Densitometry; Drug Resistance; Drug Synergism; Guanine; Humans; Male; Neoplasm Transplantation; Nimustine; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Basal Ganglia; Brain Neoplasms; Cell Count; Cell Division; Culture Techniques; DNA Repair; DNA, Neoplasm; Drug Synergism; Glioma; Guanine; Male; Nimustine; Rats; Rats, Wistar | 1994 |
O6-alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications.
Topics: Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Glioblastoma; Glioma; Humans; Methyltransferases; Neoplasm Proteins; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Tetrazolium Salts; Thiazoles | 1994 |
Induced expression and subcellular localization of the Bcl-2 protein in cultured glioma cells.
Topics: Blotting, Southern; Brain Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Microscopy, Confocal; Nimustine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1994 |
Effects of therapy on the 1H NMR spectrum of a human glioma line.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Lactates; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nimustine; Tumor Cells, Cultured | 1994 |
[Follow-up study of malignant astrocytomas showing complete response after initial treatment].
Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Nimustine; Prognosis; Radiography; Radiotherapy Dosage; Remission Induction | 1994 |
Enhancing effect of O6-alkylguanine derivatives on chloroethylnitrosourea cytotoxicity toward tumor cells.
Topics: Animals; Brain Neoplasms; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Nimustine; Rats; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Characterization and chemosensitivity of two cell lines derived from human glioblastomas.
Topics: Animals; Brain Neoplasms; Drug Resistance; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Karyotyping; Male; Methyltransferases; Mice; Mice, Inbred BALB C; Middle Aged; Neoplasm Transplantation; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Occipital Lobe; Parietal Lobe; S100 Proteins; Tumor Cells, Cultured | 1993 |
Chemotherapeutic effects of intra-arterial administration of ACNU in primary intracerebral non-Hodgkin's lymphoma.
Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Infusions, Intra-Arterial; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nimustine; Tomography, X-Ray Computed; Treatment Outcome | 1993 |
Ventriculolumbar perfusion of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosou rea hydrochloride.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebellar Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Drug; Ependymoma; Female; Follow-Up Studies; Glioblastoma; Half-Life; Humans; Injections, Intraventricular; Injections, Spinal; Male; Medulloblastoma; Meningeal Neoplasms; Metabolic Clearance Rate; Neoplasm Recurrence, Local; Neuroectodermal Tumors; Nimustine; Prohibitins; Subarachnoid Space; Survival Rate | 1993 |
[Intravascular surgery for brain tumors].
Topics: Brain Neoplasms; Carmustine; Chemoembolization, Therapeutic; Humans; Meningeal Neoplasms; Meningioma; Nimustine | 1993 |
[Brain SPECT by intraarterial infusion of 99mTc-HMPAO for assessing the cerebral distribution of carotid artery infusions in patients with brain tumor].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Carotid Artery, Internal; Etoposide; Female; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Organotechnetium Compounds; Oximes; Pulsatile Flow; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1993 |
Influence of O6-methylguanine-DNA methyltransferase activity on chloroethylnitrosourea chemotherapy in brain tumors.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Follow-Up Studies; Glioma; Humans; Male; Methyltransferases; Middle Aged; Neoplasms, Nerve Tissue; Nimustine; O(6)-Methylguanine-DNA Methyltransferase | 1993 |
Effects of high-dose chemotherapy with syngeneic bone marrow transplantation in experimental brain tumor in rats.
Topics: Animals; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Female; Leukocyte Count; Nimustine; Rats; Rats, Inbred F344 | 1993 |
[Usefulness of 201T1C1-SPECT in the evaluation of radiation and chemotherapy for brain tumors].
Topics: Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Nimustine; Thallium; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon | 1993 |
[Treatment results of intra-arterial ACNU infusion chemotherapy for primary cerebral malignant lymphoma].
Topics: Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Lymphoma; Male; Middle Aged; Nimustine; Radioisotope Teletherapy; Survival Rate | 1993 |
Enhancement of ACNU treatment of the BT4An rat glioma by local brain hyperthermia and intra-arterial drug administration.
Topics: Animals; Brain Neoplasms; Combined Modality Therapy; Glioma; Hyperthermia, Induced; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nimustine; Random Allocation; Rats; Rats, Inbred Strains; Survival Rate | 1995 |
Chemotherapy for progressive pilocytic astrocytomas in the chiasmo-hypothalamic regions.
Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Etoposide; Female; Humans; Hypothalamus; Infant; Magnetic Resonance Imaging; Male; Nimustine; Nitrosourea Compounds; Optic Chiasm | 1995 |
[Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents].
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cisplatin; Flow Cytometry; Glioma; Humans; Interferons; Nimustine; Prostaglandin D2; Tumor Cells, Cultured | 1995 |
A strategy for selective anti-cancer drug concentration increase in rat glioma tissue with Ca(2+)-channel blocker co-administration: calcium kinetics in intra-glioma arteriolar smooth muscle cells.
Topics: Animals; Antineoplastic Agents; Arterioles; Brain Neoplasms; Calcium; Calcium Channel Blockers; Diltiazem; Glioma; Kinetics; Male; Muscle, Smooth, Vascular; Nimustine; Rats; Rats, Wistar; Reference Values; Regional Blood Flow; Tumor Cells, Cultured | 1996 |
Therapy-related chronic myelomonocytic leukaemia with bone marrow eosinophilia associated with der(11)t(1;11)(q21;q14).
Topics: Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Child; Chromosome Aberrations; Eosinophilia; Fatal Outcome; Glioma; Humans; Hydroxyurea; Karyotyping; Leukemia, Myelomonocytic, Chronic; Leukocyte Count; Lymphocyte Activation; Male; Nimustine | 1996 |
[Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glioma; Guanine; Humans; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Tumor Cells, Cultured | 1997 |
Parenchymal damage in the territory of the anterior choroidal artery following supraophthalmic intracarotid administration of CDDP for treatment of malignant gliomas.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Carotid Arteries; Choroid Plexus; Cisplatin; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Retrospective Studies; Tomography, X-Ray Computed | 1997 |
Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Glutathione Transferase; Humans; Immunohistochemistry; Isoenzymes; Karnofsky Performance Status; Nimustine; Teniposide | 1997 |
[Comprehensive therapy of malignant glioma of the brain].
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Glioma; Humans; Infant; Middle Aged; Nimustine; Radioimmunotherapy; Survival Analysis; Treatment Outcome | 1997 |
Drug resistance and apoptosis in ENU-induced rat brain tumors treated with anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Nimustine; Pregnancy; Rats; Rats, Wistar; Vincristine | 1998 |
Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Immunohistochemistry; Methotrexate; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
[Evaluation of brain tumor by 99mTc-MIBI: comparison study with 201Tl and predictivity of therapeutic effect].
Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Glioblastoma; Humans; Middle Aged; Nimustine; Predictive Value of Tests; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Thallium; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon | 1998 |
[Clinical evaluation of intraoperative radiotherapy using photon radiosurgery system for brain tumors].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Humans; Nimustine; Radiosurgery; Stereotaxic Techniques; Vincristine | 1998 |
Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cisplatin; Dactinomycin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glioblastoma; Humans; Nimustine; Staurosporine; Tumor Cells, Cultured | 2000 |
Expression pattern of chemoresistance-related genes in human malignant brain tumors: a working knowledge for proper selection of anticancer drugs.
Topics: Antigens, CD; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Doxorubicin; Etoposide; Genes, MDR; Glioma; Humans; Membrane Glycoproteins; Nimustine; RNA, Messenger; Tetraspanin 29; Tumor Cells, Cultured | 1999 |
O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.
Topics: Animals; Benzyl Compounds; Brain Neoplasms; Cell Division; DNA Damage; DNA, Neoplasm; Guanine; Mice; Mice, Nude; Nimustine; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Transplantation, Heterologous | 2000 |
Effectiveness of spray application of ACNU in the local control of malignant gliomas: report of two cases.
Topics: Aerosols; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Combinations; Fibrin Tissue Adhesive; Follow-Up Studies; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Postoperative Care; Tissue Adhesives | 2000 |
Treatment of malignant brain tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Nimustine; Prognosis; Radiosurgery; Survival Rate; Vincristine | 2000 |
Clinicopathological study of oligodendroglial tumors: the effectiveness of interferon beta, ACNU/MCNU, and radiation (IAR/IMR) for anaplastic tumors.
Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Interferon-beta; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Oligodendroglioma; Retrospective Studies; Survival Analysis | 2000 |
Distinct radiochemotherapy protocols differentially influence cellular proliferation and expression of p53 and Bcl-2 in glioblastoma multiforme relapses in vivo.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Brain Neoplasms; Cell Division; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes; Genes, bcl-2; Glioblastoma; GTP-Binding Proteins; Humans; Ki-67 Antigen; Life Tables; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Nimustine; Protein Glutamine gamma Glutamyltransferase 2; Proto-Oncogene Proteins c-bcl-2; Radiotherapy, Adjuvant; Survival Analysis; Teniposide; Transglutaminases; Tumor Suppressor Protein p53 | 2000 |
The ability in adhesion and invasion of drug-resistant human glioma cells.
Topics: Animals; Brain Neoplasms; Cell Adhesion; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Extracellular Matrix Proteins; Flow Cytometry; Glioma; Humans; Matrix Metalloproteinases; Mice; Neoplasm Proteins; Neural Cell Adhesion Molecules; Nimustine; Tumor Cells, Cultured; Vincristine | 2000 |
Antitumor effect and peritumoral brain edema formation in relation to MX2, ACNU, and doxorubicin therapy: a comparative analysis using rodent models of gliomas.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Body Weight; Brain Edema; Brain Neoplasms; Carubicin; Disease Models, Animal; Doxorubicin; Glioma; Leukocyte Count; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nimustine; Rats; Survival Rate | 2000 |
Effectiveness of interferon-beta, ACNU, and radiation therapy in pediatric patients with brainstem glioma.
Topics: Adolescent; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Combined Modality Therapy; Female; Glioma; Humans; Interferon-beta; Magnetic Resonance Imaging; Male; Nimustine | 1992 |
[Intra-arterial chemotherapy with ACNU in the treatment of malignant gliomas].
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Carotid Artery, Internal; Female; Glioblastoma; Glioma; Humans; Infant, Newborn; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Prognosis; Tomography, X-Ray Computed | 1992 |
Treatment results by uneven fractionated irradiation, low-dose rate telecobalt therapy as a boost, and intraoperative irradiation for malignant glioma.
Topics: Adolescent; Adult; Aged; Brain; Brain Neoplasms; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Necrosis; Nimustine; Prognosis; Radioisotope Teletherapy; Regression Analysis | 1992 |
Cross-resistance pattern in brain tumour cells resistant to antitumour chloroethylnitrosoureas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Resistance; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
[Quantitative analysis of glutathione and glutathione S-transferase in human brain tumors, C6 rat glioma cells and drug resistant C6 cells].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Drug Resistance; Glioma; Glutathione; Glutathione Transferase; Nimustine; Rats; Tumor Cells, Cultured; Vincristine | 1992 |
Enhancement of radiosensitivity by tamoxifen in C6 glioma cells.
Topics: Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Glioma; Humans; Nimustine; Protein Kinase C; Radiation-Sensitizing Agents; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
Malignancy and viability of intraparenchymal brain tumours: correlation between Gd-DTPA contrast MR images and proliferative potentials.
Topics: Brain; Brain Neoplasms; Cell Division; Cell Survival; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Gadolinium DTPA; Glioma; Humans; Magnetic Resonance Imaging; Nimustine; Organometallic Compounds; Pentetic Acid; Premedication; Radiation Injuries | 1992 |
[Chemo-sensitivity test for malignant brain tumors by DNA histogram, in vitro].
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Nimustine; Tumor Cells, Cultured | 1992 |
[Primary intracranial melanoma: a case report].
Topics: Adult; Amphetamines; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Dacarbazine; Diagnosis, Differential; Humans; Interferon-beta; Iodine Radioisotopes; Iofetamine; Magnetic Resonance Imaging; Male; Melanoma; Nimustine; Prognosis; Tomography, Emission-Computed, Single-Photon; Vincristine | 1992 |
Modulation of BUdR labeling index in rat brain tumors following intracarotid ACNU administration.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carotid Arteries; Cell Division; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Neoplasm Transplantation; Nimustine; Rats; Time Factors; Tumor Cells, Cultured | 1992 |
Development of resistance to antitumor chloroethylnitrosoureas in vitro in brain tumor cells.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Resistance; HeLa Cells; Humans; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Wistar; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
Isolation and preliminary characterization of ACNU-resistant sublines of rat brain tumors in vivo.
Topics: Animals; Brain Neoplasms; Cell Division; Drug Resistance; Male; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tumor Cells, Cultured | 1992 |
Expression of O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea resistance of human brain tumors.
Topics: Blotting, Northern; Brain Neoplasms; Cell Survival; DNA Probes; Drug Resistance; Glioma; Humans; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Glioma; Humans; Mitomycin; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
[Treatment of malignant gliomas by selective intraarterial infusion chemotherapy with high-dose ACNU and autologous bone marrow transplantation--preliminary report].
Topics: Adolescent; Adult; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Transplantation, Autologous | 1991 |
Intra-arterial ACNU chemotherapy employing 20% mannitol osmotic blood-brain barrier disruption for malignant brain tumors.
Topics: Adolescent; Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Child; Electroencephalography; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Male; Mannitol; Middle Aged; Nimustine; Osmotic Pressure; Tomography, X-Ray Computed | 1990 |
Diffuse low-density areas in white matter on CT scans after intracarotid ACNU infusion--report of three cases.
Topics: Brain; Brain Neoplasms; Carotid Arteries; Female; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Nimustine; Tomography, X-Ray Computed | 1990 |
[Multidisciplinary therapy using interferon and immunological evaluation for glioma patients: two-color analysis of T cell subsets].
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Interferons; Male; Middle Aged; Nimustine; Picibanil; Radiotherapy Dosage; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1991 |
Complete remission of metastatic teratoma from malignant testicular tumor using salvage chemotherapy with VP-16 (etoposide), CDDP, and ACNU--case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Etoposide; Humans; Male; Nimustine; Organoplatinum Compounds; Remission Induction; Salvage Therapy; Teratoma; Testicular Neoplasms | 1991 |
Treatment of malignant glioma with high dose intra-arterial ACNU and autologous bone marrow transplantation--case report.
Topics: Adult; Agranulocytosis; Astrocytoma; Bone Marrow Transplantation; Brain Edema; Brain Neoplasms; Combined Modality Therapy; Female; Frontal Lobe; Glycerol; Humans; Injections, Intra-Arterial; Neoplasm Recurrence, Local; Nimustine; Thrombocytopenia | 1991 |
[Intrathecal distribution of ACNU by various modes of its administration analyzed by HPLC and autoradiography].
Topics: Animals; Autoradiography; Brain Neoplasms; Chromatography, High Pressure Liquid; Cisterna Magna; Dogs; Glioma; Injections, Intraventricular; Injections, Spinal; Nimustine; Perfusion | 1991 |
In vitro studies on drug interaction of ifosfamide and ACNU in primary and metastatic human brain tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Interactions; Humans; Ifosfamide; Nimustine; Tumor Cells, Cultured | 1991 |
Brain necroses after intraarterial chemotherapy and irradiation of malignant gliomas--a complication of both ACNU and BCNU?
Topics: Brain; Brain Diseases; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Glioma; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Necrosis; Nimustine; Prospective Studies; Radiation Injuries | 1991 |
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma.
Topics: Animals; Brain Neoplasms; Carmustine; Combined Modality Therapy; Drug Screening Assays, Antitumor; Drug Synergism; Glioma; Glucose; Hydrogen-Ion Concentration; Hyperthermia, Induced; Hypertonic Solutions; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred Strains; Retinal Diseases; Skin Neoplasms; Tumor Cells, Cultured | 1991 |
[In vitro chemosensitivity test with several antitumor agents against eight malignant brain tumor cell-lines].
Topics: Antineoplastic Agents; Brain Neoplasms; Drug Screening Assays, Antitumor; Humans; Interferon Type I; Methotrexate; Nimustine; Tumor Cells, Cultured; Vincristine | 1991 |
Cross-resistance patterns in ACNU-resistant glioma sublines in culture.
Topics: Animals; Brain Neoplasms; Clone Cells; Doxorubicin; Drug Resistance; Glioma; Glutathione; Hot Temperature; Nimustine; Phenotype; Radiation Tolerance; Rats; Rats, Inbred F344; Vinblastine | 1991 |
[The changes of cerebral blood flow and metabolism of normal brain tissue after surgery, radiation, and chemotherapy in brain tumor patients: evaluated by position emission tomography].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality Therapy; Cranial Irradiation; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; Radiotherapy Dosage; Tegafur; Tomography, Emission-Computed | 1990 |
[Chemotherapy with ACNU and radiation therapy in malignant glioma in cerebral hemisphere of adult].
Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Drug Evaluation; Female; Glioma; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Mannitol; Middle Aged; Nimustine; Remission Induction; Retrospective Studies; Survival Rate | 1990 |
[Combined postoperative radiotherapy and chemotherapy for malignant gliomas].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Nimustine; Proteoglycans; Retrospective Studies; Survival Rate; Vincristine | 1990 |
[Management results of primary intracranial malignant lymphoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; Cytarabine; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Nimustine; Prognosis; Radiotherapy Dosage | 1990 |
[Chemosensitivity assays for malignant gliomas].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Drug Screening Assays, Antitumor; Glioma; Humans; Male; Nimustine; Rats; Rats, Inbred F344; Vincristine | 1990 |
[Radiation injury of the normal brain tissue after external radiotherapy of brain tumor].
Topics: Aged; Aging; Antineoplastic Agents; Brain; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Necrosis; Nimustine; Radiation Injuries; Radiotherapy Dosage; Tomography, X-Ray Computed | 1990 |
[Immunohistochemical study of placental form of glutathione S-transferase in human brain tumors and fetal brains].
Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Clinical Enzyme Tests; Drug Resistance; Female; Glutathione Transferase; Humans; Immunohistochemistry; Neoplasm Recurrence, Local; Nimustine; Placenta; Pregnancy | 1990 |
[Chemotherapy in malignant gliomas].
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Combined Modality Therapy; Cytarabine; Follow-Up Studies; Glioma; Humans; Nimustine; Survival Rate; Teniposide | 1990 |
Optic nerve degeneration caused by supraophthalmic carotid artery infusion with cisplatin and ACNU. Case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blindness; Brain Neoplasms; Carotid Artery, Internal; Cisplatin; Female; Hemianopsia; Humans; Infusions, Intra-Arterial; Nerve Degeneration; Nimustine; Ophthalmic Artery; Optic Nerve Diseases | 1990 |
Sensitivity of human malignant intracranial tumors against MCNU in vitro in comparison to ACNU and BCNU.
Topics: Aged; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured | 1990 |
[Chemotherapy responsiveness of brain tumors in subrenal capsule assay].
Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Glioma; Male; Nimustine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Subrenal Capsule Assay; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vincristine | 1990 |
Neurotoxicity of local administration of two nitrosoureas in malignant gliomas.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Dose-Response Relationship, Drug; Female; Glioma; Humans; Male; Middle Aged; Neurotoxins; Nimustine; Nitrosourea Compounds | 1990 |
Modification of tumor blood flow and enhancement of therapeutic effect of ACNU on experimental rat gliomas with angiotensin II.
Topics: Angiotensin II; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Hypertension; Nimustine; Rats; Rats, Inbred Strains | 1990 |
[Interstitial hyperthermia of malignant brain tumors using implant heating system (IHS)].
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Temperature; Brain Neoplasms; Child; Cisplatin; Combined Modality Therapy; Etoposide; Female; Humans; Hyperthermia, Induced; Male; Middle Aged; Nimustine; Prostheses and Implants; Rabbits | 1990 |
Linkage between O6-methylguanine-DNA methyltransferase (O6-MT) activity and cellular resistance to antitumour nitrosoureas in cultured rat brain tumour cell strains.
Topics: Animals; Brain Neoplasms; Cell Line; Guanine; Humans; Methyltransferases; Nimustine; Nitrosourea Compounds; Rats | 1990 |
[Antineoplastic effect of Hu-IFN-beta and other anticancer drugs on malignant brain tumors in athymic nude mice].
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Ependymoma; Glioblastoma; Glioma; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Nude; Nimustine; Nitrosourea Compounds; Vincristine | 1985 |
Comparative study of chemotherapy and/or immunotherapy of established experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Combined Modality Therapy; Glioblastoma; Immunotherapy; Male; Nimustine; Nitrosourea Compounds; Propionibacterium acnes; Rats; Rats, Inbred Strains | 1985 |
[Evaluation of ACNU and 5-FU in the treatment of gliomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biological Products; Brain Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Glioblastoma; Humans; Male; Nimustine; Nitrosourea Compounds; Picibanil | 1986 |
[Multidisciplinary therapy for gliomas. Experimental study using brain tumor-bearing rats and analytical study of clinical cases].
Topics: Animals; Astrocytoma; Biological Products; Brain Neoplasms; Cobalt Radioisotopes; Combined Modality Therapy; Glioma; Humans; Nimustine; Nitrosourea Compounds; Picibanil; Rats | 1986 |
[Flow cytometric studies of brain tumors--5: New sensitivity test of antineoplastic agents for brain tumors and its clinical application].
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Cell Cycle; Cell Survival; Colony-Forming Units Assay; Flow Cytometry; Fluorouracil; Glioma; Humans; Infant; Medulloblastoma; Mitomycin; Mitomycins; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay | 1986 |
[In vitro response characteristics of brain tumor cell lines to hyperthermia].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; Glioma; Hot Temperature; Humans; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay | 1986 |
[Interaction of human fibroblast interferon with chemotherapeutic agents and radiation of human gliomas in nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Female; Glioma; Interferon Type I; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage | 1986 |
[Application of flow cytometry to the chemosensitivity test by the BrdU labeling method; a preliminary report].
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Bromodeoxyuridine; Flow Cytometry; Humans; Nimustine; Nitrosourea Compounds; Staining and Labeling | 1987 |
[Enhancing effect of reserpine upon the cytotoxicity of ACNU on ACNU-resistant glioma cells].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Membrane Permeability; Cells, Cultured; Drug Resistance; Drug Synergism; Glioma; Nimustine; Nitrosourea Compounds; Rats; Reserpine | 1986 |
[Mechanism of cellular resistance to ACNU in rat brain tumor cell line].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; DNA Repair; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats; Sister Chromatid Exchange; Tumor Stem Cell Assay | 1986 |
[DNA content and sensitivity to ACNU of human glioma cell lines].
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Cell Line; DNA, Neoplasm; Female; Glioma; Humans; Male; Nimustine; Nitrosourea Compounds | 1986 |
[Pharmacokinetics in intra-arterial ACNU therapy in malignant brain tumors].
Topics: Adolescent; Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Child; Female; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Tissue Distribution | 1987 |
[Mechanisms of cellular resistance to ACNU in cell lines derived from human brain tumors].
Topics: Brain Neoplasms; Drug Resistance; Glioma; Humans; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured | 1987 |
In vitro effects of ACNU, BCNU, CDDP, and bleomycin on human glioma cells.
Topics: Antineoplastic Agents; Bleomycin; Brain Neoplasms; Carmustine; Cell Line; Cisplatin; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Nimustine; Tumor Cells, Cultured | 1988 |
[Computed tomographic features of cerebral malignant glioma following treatment and regrowth. Tumor response to radiochemotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Child; Combined Modality Therapy; Follow-Up Studies; Glioma; Humans; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Tomography, X-Ray Computed; Vincristine | 1988 |
Effect of combined treatment with magnetic induction hyperthermia and chemotherapy in a rabbit brain tumor model.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma; Combined Modality Therapy; Female; Hyperthermia, Induced; Magnetics; Nimustine; Rabbits | 1989 |
[Cystic pineocytoma successfully treated with synchronized chemoradiotherapy. Case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Ventricle Neoplasms; Combined Modality Therapy; Female; Humans; Meningeal Neoplasms; Nimustine; Pinealoma; Remission Induction; Tomography, X-Ray Computed; Vincristine | 1989 |
[Enhancement of the effect of X-irradiation against cultured human glioblastoma cells by pretreatment with ACNU].
Topics: Brain Neoplasms; Cell Survival; Glioma; Humans; Nimustine; Tumor Cells, Cultured | 1989 |
[Therapeutic efficacy of intracarotid infusion of 20% mannitol with ACNU in Fischer rats with intracerebrally implanted 9L gliosarcoma].
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Bromodeoxyuridine; Carotid Artery, Internal; Cell Division; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Infusions, Intra-Arterial; Infusions, Parenteral; Male; Mannitol; Neoplasm Transplantation; Nimustine; Rats; Rats, Inbred F344 | 1989 |
[Intra-arterial chemotherapy of malignant glioma after osmotic blood-brain barrier disruption].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Glioma; Humans; Infusions, Intra-Arterial; Interferon Type I; Leukopenia; Male; Mannitol; Middle Aged; Nimustine; Osmotic Pressure; Remission Induction; Thrombocytopenia | 1989 |
[Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET].
Topics: Adolescent; Adult; Antineoplastic Agents; Brain; Brain Neoplasms; Carbon Radioisotopes; Cerebrovascular Circulation; Combined Modality Therapy; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glioma; Humans; Male; Middle Aged; Nimustine; Oxygen Radioisotopes; Tegafur; Tomography, Emission-Computed | 1989 |
Complete remission of recurrent glioblastoma multiforme following local infusions of lymphokine activated killer cells. Case report.
Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Frontal Lobe; Glioblastoma; Humans; Immunization, Passive; Interferon Type I; Interleukin-2; Killer Cells, Natural; Male; Neoplasm Recurrence, Local; Nimustine; Parietal Lobe; Postoperative Complications; Recombinant Proteins | 1989 |
Adjuvant intraarterial chemotherapy with nimustine in the management of World Health Organization Grade IV gliomas of the brain. Experience at the Department of Neurosurgery of Düsseldorf University.
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Neoplasm Staging; Nimustine; Radiotherapy Dosage; World Health Organization | 1989 |
Early effects of intra-arterial chemotherapy in patients with brain tumours studied with PET: preliminary results.
Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Deoxy Sugars; Deoxyglucose; Female; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Predictive Value of Tests; Prognosis; Tomography, Emission-Computed | 1989 |
Microspectrofluorometric evaluation of single- and double-stranded DNA in short-term cultured human glioma cells.
Topics: Adult; Brain Neoplasms; Child; DNA; DNA, Neoplasm; Female; Glioma; Humans; Infant; Male; Middle Aged; Nimustine; Polyploidy; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1989 |
[Chemotherapeutic strategy in rat brain tumor cells resistant to ACNU using an in vitro colony formation assay].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Nimustine; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
[A trial of ACNU and radiation therapy with sensitizing agents for malignant gliomas].
Topics: Acyclovir; Adolescent; Adult; Aged; Brain Neoplasms; Bromodeoxyuridine; Combined Modality Therapy; Evaluation Studies as Topic; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy Dosage; Remission Induction; Vidarabine | 1989 |
[Antitumor efficacy of FK 973 on malignant glioma cells].
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Methotrexate; Mice; Mice, Inbred C3H; Nimustine; Oxazines | 1989 |
[Concentration of ACNU in a branch of middle cerebral artery, femoral vein and brain tissue by intracarotid or intravenous administration in a patient with recurrent glioblastoma].
Topics: Adult; Brain; Brain Neoplasms; Carotid Artery, Internal; Cerebral Arteries; Female; Femoral Vein; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Neoplasm Recurrence, Local; Nimustine; Tissue Distribution | 1989 |
[Controlled multimodality treatment of brain stem gliomas].
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Interferon Type I; Male; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage | 1987 |
[Treatment of malignant gliomas with high-dose ACNU and autologous bone marrow transplantation].
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nimustine; Transplantation, Autologous | 1988 |
[Radiotherapy of astrocytoma].
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Nimustine; Prognosis; Radiotherapy Dosage; Remission Induction | 1988 |
[Circumvention of ACNU-resistance in rat glioma cells by pretreatment with O6-methylguanine].
Topics: Animals; Brain Neoplasms; Cell Survival; Drug Resistance; Drug Synergism; Enzyme Induction; Glioma; Guanine; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Fluorouracil; Leukemia L1210; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Streptozocin; Tegafur; Uracil | 1987 |
Intra-arterial chemotherapy with ACNU for the treatment of glioblastoma. Preliminary experience.
Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine | 1986 |
[ACNU delivery to malignant glioma tissue by osmotic blood brain barrier modification with intracarotid infusion of hyperosmoral mannitol].
Topics: Adult; Aged; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Cerebral Cortex; Combined Modality Therapy; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Male; Mannitol; Middle Aged; Nimustine; Nitrosourea Compounds; Osmolar Concentration | 1985 |
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysgerminoma; Ependymoma; Fluorouracil; Glioma; Humans; Medulloblastoma; Methylmethacrylates; Mitomycin; Mitomycins; Neoplasms, Germ Cell and Embryonal; Nimustine; Nitrosourea Compounds; Teratoma | 1986 |
[Treatment of autochthonous rat brain tumors with chemotherapy and radiotherapy].
Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Brain Neoplasms; Carboxymethylcellulose Sodium; Combined Modality Therapy; Glioma; Nimustine; Nitrosourea Compounds; Poly I-C; Polylysine; Radiotherapy Dosage; Rats; Sarcoma, Avian; Vincristine | 1987 |
Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas. Clinical aspects and critical considerations.
Topics: Astrocytoma; Brain Neoplasms; Carmustine; Carotid Arteries; Combined Modality Therapy; Follow-Up Studies; Glioblastoma; Glioma; Humans; Infusions, Intra-Arterial; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Oligodendroglioma | 1987 |
[A case of adult respiratory distress syndrome (ARDS) induced by radio-chemotherapy (RAFP therapy) of brain metastasis of stomach cancer].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Brain Neoplasms; Humans; Male; Nimustine; Nitrosourea Compounds; Proteoglycans; Radiotherapy; Respiratory Distress Syndrome; Stomach Neoplasms; Tegafur | 1986 |
[Results of combined radiochemotherapy of intracranial ependymoma].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Ventricle Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Ependymoma; Female; Fluorouracil; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; Tegafur | 1987 |
[Results of supratentorial low-grade astrocytoma--effects of combined radiochemotherapy].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Combined Modality Therapy; Humans; Nimustine; Nitrosourea Compounds; Prognosis; Proteoglycans; Radiotherapy Dosage; Tegafur | 1987 |
[AUFRAP therapy: combined modality treatment of malignant gliomas with intraarterial infusion of ACNU].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotid Artery, Internal; Combined Modality Therapy; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Proteoglycans; Radiotherapy Dosage; Remission Induction; Tegafur; Uracil; Vitamin A | 1988 |
Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy.
Topics: Adolescent; Adult; Brain; Brain Neoplasms; Cerebrovascular Circulation; Child; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Nimustine; Tegafur; Tomography, Emission-Computed | 1988 |
[A case report of brain metastasis due to an advanced gastric cancer].
Topics: Brain Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Stomach Neoplasms; Tegafur | 1988 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Floxuridine; Hydantoins; Leukemia, Myeloid; Liver Neoplasms, Experimental; Lomustine; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Procarbazine; Rats | 1985 |
[Clinico-immunological evaluation of T cells bearing IgG Fc receptors in brain tumor patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dysgerminoma; Humans; Immunoglobulin A; Immunoglobulin Fc Fragments; Immunoglobulin Fragments; Immunoglobulin M; Lymphocyte Activation; Nimustine; Nitrosourea Compounds; Phytohemagglutinins; Picibanil; Receptors, IgG; Receptors, Immunologic; T-Lymphocytes | 1985 |
[Response to antitumor agents of human transplantable glioma implanted into chorioallantoic membrane of chick embryo].
Topics: Allantois; Animals; Antineoplastic Agents; Brain Neoplasms; Chick Embryo; Chorion; Drug Screening Assays, Antitumor; Extraembryonic Membranes; Glioma; Humans; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds | 1988 |
[Intra-arterial ACNU chemotherapy of malignant glioma].
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Child; Female; Glioma; Humans; Infusions, Intra-Arterial; Male; Nimustine; Nitrosourea Compounds | 1988 |
[Mechanisms of cellular resistance to chloroethylnitrosourea in cell lines derived from human brain tumors].
Topics: Brain Neoplasms; Carmustine; Cell Line; DNA Damage; Drug Resistance; Glioma; Humans; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Cells, Cultured | 1988 |
In vitro damage of isolated DNA from two brain tumor cell lines induced by a water-soluble antitumor nitrosourea.
Topics: Animals; Brain Neoplasms; Cell Line; DNA Damage; DNA, Neoplasm; Glioma; In Vitro Techniques; Nimustine; Nitrosourea Compounds; Rats; Solubility; Water | 1988 |
[Biological basis for combined radio-chemotherapy in radioresistant tumors].
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Survival; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Neoplasms; Nimustine; Prognosis; Radiation Tolerance | 1988 |
[Effect of ACNU against experimental brain tumor--immunohistochemical study using anti-BrdU monoclonal antibody].
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Bromodeoxyuridine; Carcinoma 256, Walker; Cell Cycle; Female; Immunohistochemistry; Injections, Intravenous; Injections, Spinal; Nimustine; Rats | 1988 |
DNA lability induced by nimustine and ramustine in rat glioma cells.
Topics: Animals; Antineoplastic Agents; Base Sequence; Brain Neoplasms; Cell Line; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Nimustine; Nitrosourea Compounds; Rats; Tumor Cells, Cultured | 1988 |
[Ring enhancement on CT scan associated with the local ACNU administration therapy following glioblastoma surgery].
Topics: Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Female; Glioma; Humans; Neoplasm Recurrence, Local; Nimustine; Radiographic Image Enhancement; Reoperation; Tomography, X-Ray Computed | 1988 |
[Analysis of DNA damage induced by nitrosourea derivatives in rat brain tumor cells using a sequencing procedure].
Topics: Animals; Antineoplastic Agents; Base Sequence; Brain Neoplasms; DNA Damage; DNA, Neoplasm; DNA, Satellite; Glioma; Nimustine; Nitrosourea Compounds; Rats | 1988 |
[Combination therapy with IFN-beta, ACNU and radiation (IAR) in malignant brain tumors].
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Female; Glioma; Humans; Interferon Type I; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Radiotherapy Dosage | 1986 |
[Successful chemotherapy in postoperative brain metastasis of breast cancer using ACNU--two case reports].
Topics: Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Papillary; Female; Humans; Mastectomy; Middle Aged; Nimustine; Nitrosourea Compounds; Postoperative Period | 1986 |
[Mechanism and overcoming of resistance in ACNU-resistant sublines of rat brain tumors].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Membrane Permeability; Drug Resistance; Glioma; Nicardipine; Nifedipine; Nimustine; Nitrosourea Compounds; Rats; Verapamil | 1986 |
[Experimental studies on induced hypertension chemotherapy of intracerebral inoculated gliomas in rats].
Topics: Angiotensin II; Animals; Antineoplastic Agents; Blood Pressure; Brain Neoplasms; Cerebrovascular Circulation; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats | 1986 |
[The effect of hyperthermia and antitumor drugs on brain tumor cell lines].
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line; Cisplatin; Combined Modality Therapy; Glioma; Humans; Hyperthermia, Induced; Naphthacenes; Nimustine; Nitrosourea Compounds; Rats | 1986 |
Modulation in vitro and in vivo of ACNU resistance in a subline of C6 glioma with reserpine.
Topics: Animals; Brain Neoplasms; Cell Line; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Glioma; Male; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine | 1987 |
[Studies on the mechanism of ACNU resistance in sublines of rat C6 glioma and 9L gliosarcoma in vitro].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Membrane Permeability; Drug Resistance; Glioma; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1986 |
[Possibility of overcoming of ACNU resistance in an ACNU-resistant subline of C6 rat glioma].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Drug Therapy, Combination; Glioma; Male; Nicardipine; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Reserpine; Trifluoperazine; Verapamil | 1986 |
Influence of modes of ACNU administration on tissue and blood drug concentration in malignant brain tumors.
Topics: Adenocarcinoma; Adolescent; Adult; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Squamous Cell; Female; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Lymphoma; Male; Meningioma; Middle Aged; Nimustine; Nitrosourea Compounds | 1987 |
Distribution of radiolabeled 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitros ourea hydrochloride in rat brain tumor: intraarterial versus intravenous administration.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Carbon Radioisotopes; Injections, Intra-Arterial; Injections, Intravenous; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1987 |
[Possibility of overcoming ACNU resistance in ACNU-resistant sublines of rat brain tumors in vitro by a calmodulin inhibitor].
Topics: Animals; Brain Neoplasms; Calmodulin; Cell Line; Drug Resistance; Drug Therapy, Combination; In Vitro Techniques; Nimustine; Nitrosourea Compounds; Rats; Trifluoperazine | 1987 |
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Humans; Mechlorethamine; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange; Tumor Stem Cell Assay | 1987 |
[Overcoming of ACNU resistance in an ACNU-resistant subline of rat C6 glioma in vivo through enhanced effect of ACNU by calmodulin inhibitor].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Calmodulin; Drug Resistance; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Trifluoperazine | 1987 |
[Assessment of functional status in children with brain tumors].
Topics: Adolescent; Brain; Brain Neoplasms; Child; Female; Humans; Male; Nimustine; Nitrosourea Compounds; Personality Tests; Prognosis; Radiotherapy Dosage; Vincristine; Wechsler Scales | 1987 |
[Experimental studies on the treatment of recurrent gliomas].
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cells, Cultured; Drug Resistance; Glioma; Humans; Immunization, Passive; Interleukin-2; Killer Cells, Natural; Nimustine; Nitrosourea Compounds | 1987 |
[Combination therapy with HU IFN-beta and ACNU against malignant brain tumors, Part 1. Experimental study in vitro].
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cells, Cultured; Drug Synergism; Flow Cytometry; Glioma; Humans; Interferon Type I; Nimustine; Nitrosourea Compounds | 1985 |
Primary central nervous system lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child, Preschool; Craniotomy; Cyclophosphamide; Doxorubicin; Female; Humans; Immunoglobulin G; Immunoglobulin M; Lymphoma; Male; Middle Aged; Nimustine; Nitrosourea Compounds; Prednisone; Retrospective Studies; Tomography, X-Ray Computed; Vincristine | 1985 |
Comparison of sister-chromatid exchange induction caused by nitrosoureas that alkylate or alkylate and crosslink DNA.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Cells, Cultured; Cross-Linking Reagents; DNA; Ethylnitrosourea; Nimustine; Nitrosourea Compounds; Rats; Sister Chromatid Exchange | 1985 |
[Regional blood flow of experimental brain tumors with special reference to effects of chemotherapy and radiotherapy].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Capillary Permeability; Disease Models, Animal; Glioma; Male; Nimustine; Nitrosourea Compounds; Rats; Regional Blood Flow; Tumor Stem Cell Assay | 1985 |
ACNU-resistant mutants of 9L rat glioma cell line. Isolation and preliminary characterization of these subclones.
Topics: Animals; Brain Neoplasms; Cell Line; Drug Resistance; Glioma; Neoplasms, Experimental; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred F344 | 1985 |
[Effects of anticancer drugs on multicellular spheroid of 9L rat brain tumor].
Topics: Aclarubicin; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Glioma; Naphthacenes; Nimustine; Nitrosourea Compounds; Rats; Tumor Stem Cell Assay | 1985 |
Ocular complication of combined intracarotid chemotherapy and osmotic blood-brain barrier disruption.
Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carotid Arteries; Combined Modality Therapy; Female; Humans; Infusions, Intra-Arterial; Mannitol; Middle Aged; Nimustine; Nitrosourea Compounds; Oligodendroglioma; Ophthalmoplegia; Vision Disorders | 1985 |