Page last updated: 2024-08-22

nimorazole and Cancer of Head

nimorazole has been researched along with Cancer of Head in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's7 (26.92)29.6817
2010's14 (53.85)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Baumann, M; Besso, MJ; Bitto, V; Koi, L; Krause, M; Kurth, I; Linge, A; Löck, S; Möbius, L; Overgaard, J; Pfeifer, M; Valentini, C; Weise, C; Yaromina, A; Zips, D1
Grimm, P; Söderman, M1
Andersen, M; Eriksen, JG; Hansen, CR; Jensen, K; Overgaard, J; Saksø, M1
Bar-Deroma, R; Castadot, P; Christiaens, M; Collette, S; Giralt, J; Grant, W; Gregoire, V; Hurkmans, CW; Kazmierska, J; Monti, AF; Overgaard, J; Tomsej, M; Weber, DC1
Ajmal Ali, M; Akilarasan, M; Al-Hemaid, FMA; Chen, SM; Cheng, YH; Kogularasu, S; Liu, X; Mani, V; Umamaheswari, R1
Alsner, J; Andersen, E; Andersen, LJ; Evensen, JF; Grau, C; Hansen, HS; Hoff, CM; Johansen, J; Lassen, P; Overgaard, J; Overgaard, M; Specht, L1
Alsner, J; Busk, M; Horsman, MR; Olthof, N; Overgaard, J; Speel, EJ; Sørensen, BS1
Frederiksen, KD; Metwally, MA; Overgaard, J1
Baines, H; Bolton, S; Miles, E; Slevin, N; Thomson, D; West, C; Yang, H1
Hassan Metwally, MA; Jansen, JA; Overgaard, J1
Andersen, LJ; Bentzen, J; Eriksen, JG; Overgaard, J; Primdahl, H; Toustrup, K1
Ali, R; Grau, C; Hassan Metwally, MA; Iqbal, K; Kuddu, M; Overgaard, J; Prasad, R; Shouman, T; Strojan, P1
Ali, R; Grau, C; Hassan Metwally, MA; Kuddu, M; Overgaard, J; Shouman, T; Strojan, P1
Alsner, J; Eriksen, JG; Hamilton-Dutoit, S; Lassen, P; Overgaard, J; Tramm, T1
Andersen, L; Bentzen, J; Eriksen, JG; Evensen, JF; Grau, C; Hansen, HS; Hoff, CM; Johansen, J; Lassen, P; Overgaard, J; Overgaard, M; Specht, L1
Alsner, J; Lassen, P; Overgaard, J; Sørensen, BS; Toustrup, K; Wiuf, C1
Bishop, K; Henk, JM; Shepherd, SF1
Andersen, E; Andersen, L; Bastholt, L; Bentzen, J; Evensen, JF; Grau, C; Hansen, HS; Hansen, O; Johansen, J; Overgaard, J; Overgaard, M; Specht, L1
Alsner, J; Eriksen, JG; Horsman, MR; Nordsmark, M; Overgaard, J1
Corvò, R1
Alsner, J; Eriksen, JG; Gebski, V; Horsman, MR; Nordsmark, M; Overgaard, J1
Eriksen, JG; Overgaard, J1
Bjarnason, NH; Christiansen, M; Specht, L1
Bishop, K; Cottrill, CP; Henk, JM; Walton, MI1
Berthelsen, A; Jørgensen, K; Lindeløv, B; Overgaard, J; Overgaard, M; Rasmusson, B; Sand Hansen, H1
Cohen, MS; Mukerji, R; Samadi, AK; Timmermann, BN; Tong, X; Zhang, H1

Reviews

1 review(s) available for nimorazole and Cancer of Head

ArticleYear
Evidence-based radiation oncology in head and neck squamous cell carcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007, Volume: 85, Issue:1

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Dose Fractionation, Radiation; Evidence-Based Medicine; Head and Neck Neoplasms; Humans; Nimorazole; Radiotherapy, Conformal

2007

Trials

14 trial(s) available for nimorazole and Cancer of Head

ArticleYear
DAHANCA 28: A phase I/II feasibility study of hyperfractionated, accelerated radiotherapy with concomitant cisplatin and nimorazole (HART-CN) for patients with locally advanced, HPV/p16-negative squamous cell carcinoma of the oropharynx, hypopharynx, lary
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 148

    Topics: Carcinoma, Squamous Cell; Cisplatin; Dose Fractionation, Radiation; Feasibility Studies; Head and Neck Neoplasms; Humans; Hypopharynx; Larynx; Middle Aged; Mouth; Neoplasm Recurrence, Local; Nimorazole; Oropharynx; Papillomavirus Infections

2020
Quality assurance of radiotherapy in the ongoing EORTC 1219-DAHANCA-29 trial for HPV/p16 negative squamous cell carcinoma of the head and neck: Results of the benchmark case procedure.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 123, Issue:3

    Topics: Benchmarking; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Nimorazole; Organs at Risk; Prospective Studies; Quality Assurance, Health Care; Radiotherapy Planning, Computer-Assisted; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck

2017
DAHANCA 10 - Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Darbepoetin alfa; Disease-Free Survival; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Hemoglobins; Humans; Male; Middle Aged; Nimorazole; Oxygen; Patient Compliance; Radiation-Sensitizing Agents; Squamous Cell Carcinoma of Head and Neck

2018
NIMRAD - a phase III trial to investigate the use of nimorazole hypoxia modification with intensity-modulated radiotherapy in head and neck cancer.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2014, Volume: 26, Issue:6

    Topics: Antitrichomonal Agents; Carcinoma, Squamous Cell; Cell Hypoxia; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Nimorazole; Radiation-Sensitizing Agents; Radiotherapy, Intensity-Modulated; Research Design; Squamous Cell Carcinoma of Head and Neck

2014
Locally advanced head and neck cancer treated with accelerated radiotherapy, the hypoxic modifier nimorazole and weekly cisplatin. Results from the DAHANCA 18 phase II study.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nimorazole; Squamous Cell Carcinoma of Head and Neck

2015
IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hypoxia; Male; Middle Aged; Neoplasm Staging; Nimorazole; Patient Compliance; Radiation-Sensitizing Agents; Squamous Cell Carcinoma of Head and Neck

2015
Does transfusion improve the outcome for HNSCC patients treated with radiotherapy? - results from the randomized DAHANCA 5 and 7 trials.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:7

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Erythrocyte Transfusion; Female; Head and Neck Neoplasms; Hemoglobins; Humans; Male; Middle Aged; Nimorazole; Radiotherapy; Survival Analysis

2011
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Cell Hypoxia; Chi-Square Distribution; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nimorazole; Predictive Value of Tests; Proportional Hazards Models; Radiation-Sensitizing Agents; Survival Rate

2012
Treatment of head and neck cancer with CHART and nimorazole: phase II study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 66, Issue:1

    Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Nimorazole; Palliative Care; Prognosis; Radiation Dosage; Risk Assessment; Survival Analysis; Terminally Ill; Treatment Outcome

2003
Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6 and 7 randomised controlled trial.
    Lancet (London, England), 2003, Sep-20, Volume: 362, Issue:9388

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Denmark; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nimorazole; Proportional Hazards Models; Radiation-Sensitizing Agents; Radiotherapy Dosage; Survival Rate; Treatment Outcome

2003
Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:10

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Child; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nimorazole; Osteopontin; Placebos; Radiation-Sensitizing Agents; Sialoglycoproteins; Survival Analysis

2005
Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007, Volume: 83, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Combined Modality Therapy; Drug Screening Assays, Antitumor; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Male; Middle Aged; Nimorazole; Osteopontin; Oxygen; Prospective Studies; Radiation-Sensitizing Agents; Risk Assessment

2007
Pilot study of nimorazole as a hypoxic-cell sensitizer with the "chart" regimen in head and neck cancer.
    International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4

    Topics: Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Nimorazole; Pilot Projects; Radiation-Sensitizing Agents

1998
Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1991, Volume: 20 Suppl 1

    Topics: Carcinoma; Combined Modality Therapy; Denmark; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Nimorazole; Radiation-Sensitizing Agents

1991

Other Studies

11 other study(ies) available for nimorazole and Cancer of Head

ArticleYear
Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts.
    Journal of translational medicine, 2023, 08-26, Volume: 21, Issue:1

    Topics: Chemoradiotherapy; Head and Neck Neoplasms; Heterografts; Humans; Hypoxia; Nimorazole; Prognosis; Squamous Cell Carcinoma of Head and Neck

2023
Phlegmasia cerulea dolens in a patient treated with carboplatin.
    BMJ case reports, 2020, Apr-14, Volume: 13, Issue:4

    Topics: Aged; Carboplatin; Chemoradiotherapy; Female; Fibrinolytic Agents; Head and Neck Neoplasms; Heparin, Low-Molecular-Weight; Humans; Leg; Neoplasms, Squamous Cell; Neoplasms, Unknown Primary; Nimorazole; Surgical Procedures, Operative; Thrombophlebitis; Venous Thrombosis

2020
One-pot synthesis of three-dimensional Mn
    Journal of colloid and interface science, 2017, Nov-01, Volume: 505

    Topics: Antitrichomonal Agents; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Head and Neck Neoplasms; Humans; Manganese Compounds; Nimorazole; Oxides; Tablets

2017
Radiosensitivity and effect of hypoxia in HPV positive head and neck cancer cells.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Head and Neck Neoplasms; Humans; Neoplasm Proteins; Nimorazole; Papillomaviridae; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck

2013
Compliance and toxicity of the hypoxic radiosensitizer nimorazole in the treatment of patients with head and neck squamous cell carcinoma (HNSCC).
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:5

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Medication Adherence; Middle Aged; Nimorazole; Radiation-Sensitizing Agents; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck

2014
Study of the population pharmacokinetic characteristics of nimorazole in head and neck cancer patients treated in the DAHANCA-5 trial.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nimorazole; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Squamous Cell Carcinoma of Head and Neck

2015
Radiotherapy quality assurance of the IAEA-HypoX trial of the accelerated radiotherapy in the treatment of head and neck squamous cell carcinoma with or without the hypoxic radiosensitizer nimorazole.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Guideline Adherence; Head and Neck Neoplasms; Humans; Medical Audit; Multicenter Studies as Topic; Nimorazole; Practice Guidelines as Topic; Quality Assurance, Health Care; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Retrospective Studies

2015
HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 94, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antitrichomonal Agents; Carcinoma, Squamous Cell; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, p16; Head and Neck Neoplasms; Humans; Hypoxia; Male; Middle Aged; Neoplasm Staging; Nimorazole; Retrospective Studies; Treatment Outcome

2010
Lack of prognostic and predictive value of CA IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: an evaluation of the DAHANCA 5 study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2007, Volume: 83, Issue:3

    Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Cells, Cultured; Disease-Free Survival; Follow-Up Studies; Head and Neck Neoplasms; Humans; Immunohistochemistry; Nimorazole; Predictive Value of Tests; Prognosis; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic

2007
The nimorazole regimen in patients with head and neck cancer can increase the effect of vitamin K antagonists.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:1

    Topics: Aged; Aged, 80 and over; Drug Interactions; Female; Fibrinolysis; Glottis; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; International Normalized Ratio; Laryngeal Neoplasms; Male; Nimorazole; Vitamin K

2008
Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.
    Journal of natural products, 2010, Sep-24, Volume: 73, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Argentina; Carcinoma, Squamous Cell; Cell Cycle; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; Molecular Structure; Plants, Medicinal; Solanaceae; Withanolides

2010