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nimodipine and Vitreoretinopathy, Proliferative

nimodipine has been researched along with Vitreoretinopathy, Proliferative in 1 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Vitreoretinopathy, Proliferative: Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.

Research Excerpts

ExcerptRelevanceReference
"Nimodipine can inhibit the expression of VEGF at certain degrees."1.32[Experimental study of nimodipine and vascular endothelial growth factor in proliferative retinopathy]. ( Deng, DY; Han, LR; Kong, Y; Peng, YJ, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kong, Y1
Han, LR1
Peng, YJ1
Deng, DY1

Other Studies

1 other study available for nimodipine and Vitreoretinopathy, Proliferative

ArticleYear
[Experimental study of nimodipine and vascular endothelial growth factor in proliferative retinopathy].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2004, Volume: 40, Issue:5

    Topics: Animals; Calcium Channel Blockers; Nimodipine; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal

2004