Page last updated: 2024-11-01

nimodipine and Thiamine Deficiency

nimodipine has been researched along with Thiamine Deficiency in 2 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)

Research Excerpts

ExcerptRelevanceReference
"The effect of the calcium channel blocker nimodipine on the previously described regional cerebral acidosis accompanying thiamine deficiency was investigated."7.67Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat. ( Hakim, AM; Vogel, S, 1988)
"The effect of the calcium channel blocker nimodipine on the previously described regional cerebral acidosis accompanying thiamine deficiency was investigated."3.67Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat. ( Hakim, AM; Vogel, S, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hazell, AS1
Hakim, AM2
Senterman, MK1
Hogan, MJ1
Vogel, S1

Other Studies

2 other studies available for nimodipine and Thiamine Deficiency

ArticleYear
Regional activation of L-type voltage-sensitive calcium channels in experimental thiamine deficiency.
    Journal of neuroscience research, 1998, Jun-15, Volume: 52, Issue:6

    Topics: Animals; Autoradiography; Brain; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Enzy

1998
Effect of nimodipine on the regional cerebral acidosis accompanying thiamine deficiency in the rat.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: Animals; Body Weight; Brain; Cerebrovascular Circulation; Hydrogen-Ion Concentration; Male; Nimodipi

1988