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nimodipine and Retinal Degeneration

nimodipine has been researched along with Retinal Degeneration in 1 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research Excerpts

ExcerptRelevanceReference
" In the current study, we investigated the effect of nimodipine, a specific voltage-sensitive calcium channel blocker, in light-induced retinal degeneration to further define the factors involved in the retinal degenerative process."7.68Nimodipine, a voltage-sensitive calcium channel antagonist, fails to ameliorate light-induced retinal degeneration in rat. ( Edward, DP; Lam, TT; Li, JP; Tso, MO, 1991)
" In the current study, we investigated the effect of nimodipine, a specific voltage-sensitive calcium channel blocker, in light-induced retinal degeneration to further define the factors involved in the retinal degenerative process."3.68Nimodipine, a voltage-sensitive calcium channel antagonist, fails to ameliorate light-induced retinal degeneration in rat. ( Edward, DP; Lam, TT; Li, JP; Tso, MO, 1991)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, JP1
Edward, DP1
Lam, TT1
Tso, MO1

Other Studies

1 other study available for nimodipine and Retinal Degeneration

ArticleYear
Nimodipine, a voltage-sensitive calcium channel antagonist, fails to ameliorate light-induced retinal degeneration in rat.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 72, Issue:3

    Topics: Animals; Light; Male; Nimodipine; Rats; Rats, Inbred Lew; Retina; Retinal Degeneration; Rhodopsin

1991