Page last updated: 2024-11-01

nimodipine and Reperfusion Injury

nimodipine has been researched along with Reperfusion Injury in 34 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"The aim: To see whether nimodipine had neuroprotective effects in cerebral ischemia/reperfusion injury."8.12POTENTIAL PROTECTIVE EFFECTS OF NIMODIPINE FROM CEREBRAI ISCHEMIA REPERFUSION INJURY IN RATS. ( Al-Mudhafar, A; Fakharaldeen, Z; Hadi, N; Radhi, A, 2022)
" The aim of the present study was to investigate effects of intraperitoneal administration of nimodipine on ischemia-reperfusion injury in ovaries."7.85Protective effects of intraperitoneal administration of nimodipine on ischemia-reperfusion injury in ovaries: Histological and biochemical assessments in a rat model. ( Behroozi-Lak, T; Farhad, N; Mohammadi, R; Moloody-Tapeh, M; Zarei, L, 2017)
"To compare the individual effects of baicalin and jasminoidin with the combined effect of them on cerebral ischemia-reperfusion injury, and test whether the combined administration of baicalin and jasminoidin can improve the therapeutic effect."7.73A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury. ( Li, P; Li, PT; Sun, ZH; Wang, YY; Wang, Z; Zhang, WS; Zhang, XJ; Zhang, ZJ, 2006)
"The protective effect of the calcium channel blocker nimodipine on liver ischemia and reperfusion was studied in the rat."7.69Ischemia and reperfusion injury of the rat liver: the role of nimodipine. ( Calne, RY; Chávez-Cartaya, RE; Jamieson, NV; Pino DeSola, G; Ramirez-Romero, P, 1996)
"Reperfusion injury is a pathophysiological entity distinct from the primary ischaemic injury; the oxygen arriving with blood recirculation, although necessary for alleviating the ischaemic status, may be harmful and provoke additional injury in the already damaged tissue."5.29Can nimodipine prevent ischaemic reperfusion injury in the rat brain? ( Albariño, AR; Carceller, F; Díez-Tejedor, E; Gutiérrez-Molina, M; López-Pajares, R; Roda, JM, 1993)
"The aim: To see whether nimodipine had neuroprotective effects in cerebral ischemia/reperfusion injury."4.12POTENTIAL PROTECTIVE EFFECTS OF NIMODIPINE FROM CEREBRAI ISCHEMIA REPERFUSION INJURY IN RATS. ( Al-Mudhafar, A; Fakharaldeen, Z; Hadi, N; Radhi, A, 2022)
" The aim of the present study was to investigate effects of intraperitoneal administration of nimodipine on ischemia-reperfusion injury in ovaries."3.85Protective effects of intraperitoneal administration of nimodipine on ischemia-reperfusion injury in ovaries: Histological and biochemical assessments in a rat model. ( Behroozi-Lak, T; Farhad, N; Mohammadi, R; Moloody-Tapeh, M; Zarei, L, 2017)
"To compare the individual effects of baicalin and jasminoidin with the combined effect of them on cerebral ischemia-reperfusion injury, and test whether the combined administration of baicalin and jasminoidin can improve the therapeutic effect."3.73A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury. ( Li, P; Li, PT; Sun, ZH; Wang, YY; Wang, Z; Zhang, WS; Zhang, XJ; Zhang, ZJ, 2006)
"The protective effect of the calcium channel blocker nimodipine on liver ischemia and reperfusion was studied in the rat."3.69Ischemia and reperfusion injury of the rat liver: the role of nimodipine. ( Calne, RY; Chávez-Cartaya, RE; Jamieson, NV; Pino DeSola, G; Ramirez-Romero, P, 1996)
"breviscapus on cerebral ischemia and its possible mechanism were discussed from the perspective of brain inflammatory pathway and intestinal CYP3A4, which depends on intestinal flora."1.91Effects of breviscapine on cerebral ischemia-reperfusion injury and intestinal flora imbalance by regulating the TLR4/MyD88/NF-κB signaling pathway in rats. ( Chen, HD; Jiang, MZ; Lai, Y; Lan, H; Li, X; Yang, WQ; Zhao, YY, 2023)
"The animal model of cerebral infarction induced by Middle Cerebral Artery Occlusion (MCAO) was blocked by the suture method."1.56Protective Effect of Paeoniflorin on Acute Cerebral Infarction in Rats. ( Bao, X; Chen, Z; Feng, X; Ma, X; Qiu, C; Tao, X; Wu, W; Yang, J; Zhu, Q, 2020)
"flower on cerebral ischemia-reperfusion injury in rats."1.51Protective effect of extract of the Camellia japonica L. on cerebral ischemia-reperfusion injury in rats. ( Lu, W; Wen, J; Xv, L, 2019)
"Ischemia-reperfusion injury was induced by the four-vessel occlusion method and continued for 30 days."1.39The molecular and electrophysiological mechanism of buyanghuanwu decoction in learning and memory ability of vascular dementia rats. ( Hongbo, Z; Jinglong, T; Jun, L; Shasha, L; Tao, Q; Weijuan, G, 2013)
"A rat model of cerebral ischemia and reperfusion injury was established using the middle cerebral artery occlusion (MCAO) model."1.38Effect of aloe polysaccharide on caspase-3 expression following cerebral ischemia and reperfusion injury in rats. ( Deng, YJ; Lu, JX; Lu, ZQ, 2012)
"Rats were subjected to transient middle cerebral artery occlusion (MCAO) model using the intraluminal thread."1.35Total saponins of Panax notoginseng modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischemia-reperfusion. ( Chen, BY; Deng, CQ; Li, H; Liang, Y; Luo, XG; Zhang, SP, 2009)
"We describe subarachnoid hemorrhage (SAH) in a 66-year-old man, who underwent technically successful carotid stenting for a string-stenosis of the right internal carotid artery (ICA) in a presence of contralateral ICA occlusion with recurrent right hemisphere transient ischemic attacks."1.34Subarachnoid hemorrhage after carotid artery stenting. ( Kablak-Ziembicka, A; Moczulski, Z; Motyl, R; Pieniazek, P; Przewlocki, T; Tracz, W, 2007)
"Nimodipine pretreatment (4 mg/kg, i."1.32Nimodipine attenuates biochemical, behavioral and histopathological alterations induced by acute transient and long-term bilateral common carotid occlusion in rats. ( Acharya, SB; Hota, D; Kumar, M; Rai, S; Yanpallewar, SU, 2004)
"Reperfusion injury is a pathophysiological entity distinct from the primary ischaemic injury; the oxygen arriving with blood recirculation, although necessary for alleviating the ischaemic status, may be harmful and provoke additional injury in the already damaged tissue."1.29Can nimodipine prevent ischaemic reperfusion injury in the rat brain? ( Albariño, AR; Carceller, F; Díez-Tejedor, E; Gutiérrez-Molina, M; López-Pajares, R; Roda, JM, 1993)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's8 (23.53)18.2507
2000's10 (29.41)29.6817
2010's10 (29.41)24.3611
2020's5 (14.71)2.80

Authors

AuthorsStudies
Chen, HD1
Jiang, MZ1
Zhao, YY1
Li, X1
Lan, H1
Yang, WQ1
Lai, Y1
Chen, H3
Chen, S3
Zhang, H3
Wang, S3
Li, Y5
Meng, X3
Fakharaldeen, Z1
Al-Mudhafar, A1
Radhi, A1
Hadi, N1
Wu, W1
Qiu, C1
Feng, X1
Tao, X1
Zhu, Q1
Chen, Z1
Ma, X1
Yang, J2
Bao, X1
Chen, X1
Yao, Z1
Peng, X1
Wu, L1
Wu, H1
Ou, Y1
Lai, J1
Lu, W1
Xv, L1
Wen, J1
Jinglong, T1
Weijuan, G1
Jun, L1
Tao, Q1
Hongbo, Z1
Shasha, L1
Chen, L1
Zhao, Y1
Zhang, T1
Dang, X1
Xie, R1
Li, Z2
Zhao, W1
Song, H1
Tang, H1
Tang, Y1
Li, N1
Shi, Q1
Guo, J1
Shang, E1
Duan, JA1
Wang, X1
Wang, C1
Yang, Y1
Ni, J1
Behroozi-Lak, T1
Zarei, L1
Moloody-Tapeh, M1
Farhad, N1
Mohammadi, R1
Li, H1
Deng, CQ1
Chen, BY1
Zhang, SP1
Liang, Y1
Luo, XG1
Babu, CS1
Ramanathan, M1
Li, J1
Lu, J1
Zhang, Y1
Zhu, Z1
Wan, H1
Mo, ZT1
Fang, YQ1
He, YP1
Zhang, S1
Lu, ZQ1
Deng, YJ1
Lu, JX1
Sobrado, M1
López, MG1
Carceller, F3
García, AG1
Roda, JM3
Yanpallewar, SU1
Hota, D1
Rai, S1
Kumar, M1
Acharya, SB1
Lin, XM1
Gong, PL1
Zeng, FD1
Du, GH1
Fu, YH1
Xu, J1
Zhang, JS1
Zhang, ZJ1
Li, P1
Wang, Z1
Li, PT1
Zhang, WS1
Sun, ZH1
Zhang, XJ1
Wang, YY1
Przewlocki, T1
Pieniazek, P1
Kablak-Ziembicka, A1
Motyl, R1
Moczulski, Z1
Tracz, W1
Fröba, G1
Bracht, H1
Hauser, B1
Chkhouta, AB1
Huber-Lang, M1
Rittirsch, D1
Brückner, UB1
Radermacher, P1
Schelzig, H1
Kaptanoglu, L1
Kapan, M1
Kapan, S1
Goksoy, E1
Oktar, H1
Díez-Tejedor, E2
Avendaño, C1
Gutiérrez-Molina, M1
López-Pajares, R1
Albariño, AR1
Stanimirovic, DB1
Micic, DV1
Markovic, M1
Spatz, M1
Mrsulja, BB1
Chávez-Cartaya, RE1
Pino DeSola, G1
Ramirez-Romero, P1
Calne, RY1
Jamieson, NV1
Rhee, RY1
Gloviczki, P1
Cambria, RA1
Lowell, RC1
Okazaki, H1
Ichihara, S1
Tsuda, Y1
Hosomi, N1
Kitadai, M1
Matsuo, H1
He, MX1
Ke, J1
Li, ZG1
Liu, FZ1
Kawaguchi, K1
Henshall, DC1
Simon, RP1
Liu, XD1
Pan, GY1
Xie, L1
Hou, YY1
Lan, W1
Su, Q1
Liu, GQ1
Prough, DS1
Furberg, CD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Study on the Treatment of Hypertensive Cerebral Hemorrhage With Panax Notoginseng Saponins[NCT02999048]Phase 490 participants (Actual)Interventional2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

34 other studies available for nimodipine and Reperfusion Injury

ArticleYear
Effects of breviscapine on cerebral ischemia-reperfusion injury and intestinal flora imbalance by regulating the TLR4/MyD88/NF-κB signaling pathway in rats.
    Journal of ethnopharmacology, 2023, Jan-10, Volume: 300

    Topics: Animals; Brain Ischemia; Cytochrome P-450 CYP3A; Drugs, Chinese Herbal; Erigeron; Flavonoids; Gastro

2023
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
N-methyl-D-aspartate receptor-mediated spinal cord ischemia-reperfusion injury and its protective mechanism.
    Folia neuropathologica, 2022, Volume: 60, Issue:3

    Topics: Animals; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury

2022
POTENTIAL PROTECTIVE EFFECTS OF NIMODIPINE FROM CEREBRAI ISCHEMIA REPERFUSION INJURY IN RATS.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2022, Volume: 75, Issue:12

    Topics: Animals; Antioxidants; Brain Ischemia; Cerebral Infarction; Intercellular Adhesion Molecule-1; Inter

2022
Protective Effect of Paeoniflorin on Acute Cerebral Infarction in Rats.
    Current pharmaceutical biotechnology, 2020, Volume: 21, Issue:8

    Topics: Acute Disease; Animals; Brain; Cerebral Infarction; Disease Models, Animal; Glucosides; Lipid Peroxi

2020
Eupafolin alleviates cerebral ischemia/reperfusion injury in rats via blocking the TLR4/NF‑κB signaling pathway.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Brain Ischemia; China; Flavones; Infarction, Middle Cerebral Artery; Inflammatio

2020
Protective effect of extract of the Camellia japonica L. on cerebral ischemia-reperfusion injury in rats.
    Arquivos de neuro-psiquiatria, 2019, Volume: 77, Issue:1

    Topics: Animals; Brain Ischemia; Camellia; Disease Models, Animal; Female; Immunoglobulin G; L-Lactate Dehyd

2019
The molecular and electrophysiological mechanism of buyanghuanwu decoction in learning and memory ability of vascular dementia rats.
    Brain research bulletin, 2013, Volume: 99

    Topics: Action Potentials; Animals; Apoptosis; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protei

2013
Protective effect of Sheng-Nao-Kang decoction on focal cerebral ischemia-reperfusion injury in rats.
    Journal of ethnopharmacology, 2014, Volume: 151, Issue:1

    Topics: Abietanes; Animals; Brain Ischemia; Caffeic Acids; Caspase 3; Catechols; Dose-Response Relationship,

2014
Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 118

    Topics: Amino Acids; Animals; Antioxidants; Apigenin; Brain; Brain Injuries; Brain Ischemia; CA1 Region, Hip

2014
New monocyte locomotion inhibitory factor analogs protect against cerebral ischemia-reperfusion injury in rats.
    Bosnian journal of basic medical sciences, 2017, Aug-20, Volume: 17, Issue:3

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Infarction, Middle Cerebral Artery; Interleukin-1

2017
Protective effects of intraperitoneal administration of nimodipine on ischemia-reperfusion injury in ovaries: Histological and biochemical assessments in a rat model.
    Journal of pediatric surgery, 2017, Volume: 52, Issue:4

    Topics: Animals; Biomarkers; Calcium Channel Blockers; Female; Injections, Intraperitoneal; Nimodipine; Ovar

2017
Total saponins of Panax notoginseng modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischemia-reperfusion.
    Journal of ethnopharmacology, 2009, Jan-30, Volume: 121, Issue:3

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspase Inhibitors; Female; Infarction, Middle Cerebral A

2009
Post-ischemic administration of nimodipine following focal cerebral ischemic-reperfusion injury in rats alleviated excitotoxicity, neurobehavioural alterations and partially the bioenergetics.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Calcium Channel Blockers; Glutamate-Ammonia Ligase

2011
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
    Journal of ethnopharmacology, 2012, Mar-06, Volume: 140, Issue:1

    Topics: Animals; Astragalus Plant; Cardiovascular Agents; Caspase 3; Disease Models, Animal; Drug Synergism;

2012
β-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:6

    Topics: Acorus; Allylbenzene Derivatives; Animals; Anisoles; Apoptosis Regulatory Proteins; Autophagy; Becli

2012
Effect of aloe polysaccharide on caspase-3 expression following cerebral ischemia and reperfusion injury in rats.
    Molecular medicine reports, 2012, Volume: 6, Issue:2

    Topics: Aloe; Animals; Brain Ischemia; Caspase 3; Cerebral Cortex; Gene Expression Regulation, Enzymologic;

2012
Combined nimodipine and citicoline reduce infarct size, attenuate apoptosis and increase bcl-2 expression after focal cerebral ischemia.
    Neuroscience, 2003, Volume: 118, Issue:1

    Topics: Animals; Apoptosis; Brain Ischemia; Calcium Channel Blockers; Cerebral Cortex; Cerebral Infarction;

2003
Nimodipine attenuates biochemical, behavioral and histopathological alterations induced by acute transient and long-term bilateral common carotid occlusion in rats.
    Pharmacological research, 2004, Volume: 49, Issue:2

    Topics: Animals; Brain; Carotid Artery, Common; Carotid Stenosis; Cerebrovascular Circulation; Escape Reacti

2004
Effects of Gingko biloba extract on gap junction changes induced by reperfusion/reoxygenation after ischemia/hypoxia in rat brain.
    The American journal of Chinese medicine, 2005, Volume: 33, Issue:6

    Topics: Animals; Astrocytes; Brain Ischemia; Cell Communication; Cells, Cultured; Connexin 43; Gap Junctions

2005
[Changes of expression of the P38 MAPK and caspase-3 in rat retinal ischemia-reperfusion model and the influence of Nimodipine].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2006, Volume: 42, Issue:5

    Topics: Animals; Calcium Channel Blockers; Caspase 3; Female; Male; Nimodipine; p38 Mitogen-Activated Protei

2006
A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury.
    Brain research, 2006, Dec-06, Volume: 1123, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caspase 3;

2006
Subarachnoid hemorrhage after carotid artery stenting.
    Journal of vascular surgery, 2007, Volume: 45, Issue:5

    Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Headache; Humans; Infusions, Intravenous; Ischemic

2007
Effects of intrarenal administration of the calcium antagonist nimodipine during porcine aortic occlusion-induced ischemia/reperfusion injury.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:6

    Topics: Animals; Aorta; Apoptosis; Calcium; Calcium Channel Blockers; Cyclin-Dependent Kinase Inhibitor p21;

2008
Effects of nimodipine and pentoxyfylline in prevention of hepatic ischemic damage in rats at normal and hypothermic conditions.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Hypothermia; L

2008
Reduction of infarct size by intra-arterial nimodipine administered at reperfusion in a rat model of partially reversible brain focal ischemia.
    Stroke, 1995, Volume: 26, Issue:10

    Topics: Animals; Blood Pressure; Brain Edema; Calcium Channel Blockers; Carotid Artery, External; Cerebral A

1995
Can nimodipine prevent ischaemic reperfusion injury in the rat brain?
    Neurological research, 1993, Volume: 15, Issue:6

    Topics: Animals; Brain; Brain Ischemia; Disease Models, Animal; Evoked Potentials, Somatosensory; Nimodipine

1993
'Therapeutic window's for multiple drug treatment of experimental cerebral ischemia in gerbils.
    Neurochemical research, 1994, Volume: 19, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Therapy, Combination; Gerbillinae; Ischemic Attack, Trans

1994
Ischemia and reperfusion injury of the rat liver: the role of nimodipine.
    The Journal of surgical research, 1996, Volume: 60, Issue:1

    Topics: Animals; Calcium Channel Blockers; Hemoglobins; Ischemia; Liver; Liver Circulation; Male; Microcircu

1996
The effects of nimodipine on ischemic injury of the spinal cord during thoracic aortic cross-clamping.
    International angiology : a journal of the International Union of Angiology, 1996, Volume: 15, Issue:2

    Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Constriction; Dogs; Hyperemia; Laser-Doppler Flo

1996
Nimodipine improves brain energy metabolism and blood rheology during ischemia and reperfusion in the gerbil brain.
    Journal of the neurological sciences, 1996, Volume: 144, Issue:1-2

    Topics: Animals; Brain; Calcium Channel Blockers; Cerebrovascular Circulation; Drug Evaluation, Preclinical;

1996
Effects of nimodipine on acute cerebral ischemia and reperfusion injury of rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:4

    Topics: Animals; Biogenic Monoamines; Brain Ischemia; Calcium Channel Blockers; Cerebral Cortex; Electroence

1996
Parallel dose-response studies of the voltage-dependent Na+ channel antagonist BW619C89, and the voltage-dependent Ca2+ channel antagonist nimodipine, in rat transient focal cerebral ischaemia.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Animals; Blood Glucose; Blood Pressure; Body Temperature; Brain; Calcium Channel Blockers; Dose-Resp

1999
Cyclosporin A enhanced protection of nimodipine against brain damage induced by hypoxia-ischemia in mice and rats.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Ischemia; Calcium Channel Bl

2002
Nimodipine and the "no-reflow phenomenon"--experimental triumph, clinical failure?
    Anesthesia and analgesia, 1989, Volume: 68, Issue:4

    Topics: Cerebrovascular Circulation; Heart Arrest; Humans; Nimodipine; Reperfusion Injury

1989