nimodipine has been researched along with Recrudescence in 22 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the efficacy of oral nimodipine in reducing cerebral infarction and poor outcomes (death and severe disability) after subarachnoid haemorrhage." | 9.06 | Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. ( Foy, PM; Humphrey, PR; Illingworth, R; Lang, DA; Murray, GD; Nelson, R; Pickard, JD; Richards, P; Shaw, MD; Teasdale, GM, 1989) |
| "The effect of intravenous nimodipine on the incidence of mortality and delayed ischemic neurological deficits of patients after aneurysmal subarachnoid hemorrhage (SAH) and surgery was studied in a prospective double-blind placebo-controlled trial." | 9.06 | Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J, 1988) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 9.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their subarachnoid hemorrhage, to determine whether treatment with the calcium blocker nimodipine would prevent or reduce the severity of ischemic neurologic deficits from arterial spasm." | 9.05 | Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage. ( Ahn, HS; Allen, GS; Battye, R; Bertsch, LA; Boisvert, DP; Boone, SC; Chou, SN; Crabbe, RA; Dorsey, FC; Hundley, MB; Ingram, CR; Johnson, RK; Kelly, DL; Lavik, PJ; Mellits, DE; Preziosi, TJ; Rosenbloom, SB; Strom, JA; Transou, CR; Weir, BK, 1983) |
| "The authors report findings from a metaanalysis of all published randomized trials of prophylactic nimodipine used in patients who have experienced subarachnoid hemorrhage (SAH)." | 8.79 | Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: a metaanalysis. ( Barker, FG; Ogilvy, CS, 1996) |
| " He was treated with oral nimodipine (30 mg every 8 hours), which alleviated the headache and prevented its recurrence." | 7.79 | Orgasmic headache treated with nimodipine. ( Ha, YS; Lee, HS; Lee, JW; Park, SC; Seo, IY, 2013) |
| "We sought to determine the effects of two different calcium channel antagonists, S-emopamil and nimodipine, on hippocampal glutamate and glycine release and to compare their effects to those of mild hypothermia." | 7.68 | Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits. ( Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH, 1993) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 7.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| "Nimodipine treatment was associated with a significant increase of survival (11." | 5.29 | [Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve]. ( Bazin, A; Bernard, MH; Bertault, R; Gomis, P; Graftieaux, JP; Peruzzi, P; Rousseaux, P; Scherpereel, B, 1993) |
| "Two calcium antagonists were used to treat vertigo (nimodipine, 89 patients; cinnarizine, 92 patients), and all patients were maintained on the same dosage regimen until they completed 12 weeks of treatment." | 5.10 | New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study. ( Abiuso, J; Alegría, J; Arenas, JE; Castañeda, JR; F, GV; Flaskamp, R; Gómez, JM; González, RH; Guerra, OJ; Hanuch, E; Hernández, J; Hidalgo, LO; Madrid, CE; Martínez, C; Morán, LM; Pedraza, A; Pianese, CP; Ponce, JE; Quijano, D; Ramírez, AM; Rubio, AT; Sanjuán, AP; Uribe, JO; Volpi, C, 2002) |
| "To determine the efficacy of oral nimodipine in reducing cerebral infarction and poor outcomes (death and severe disability) after subarachnoid haemorrhage." | 5.06 | Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. ( Foy, PM; Humphrey, PR; Illingworth, R; Lang, DA; Murray, GD; Nelson, R; Pickard, JD; Richards, P; Shaw, MD; Teasdale, GM, 1989) |
| "The effect of intravenous nimodipine on the incidence of mortality and delayed ischemic neurological deficits of patients after aneurysmal subarachnoid hemorrhage (SAH) and surgery was studied in a prospective double-blind placebo-controlled trial." | 5.06 | Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery. ( Heiskanen, O; Ohman, J, 1988) |
| "We enrolled 75 consecutive patients admitted with subarachnoid hemorrhages in a randomized, double-blind, placebo-controlled trial to determine the effect of early intervention with nimodipine on outcome and cerebral blood flow." | 5.06 | Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage. ( Dorrance, D; Lowe, D; Mee, E; Neil-Dwyer, G, 1988) |
| "We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their subarachnoid hemorrhage, to determine whether treatment with the calcium blocker nimodipine would prevent or reduce the severity of ischemic neurologic deficits from arterial spasm." | 5.05 | Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage. ( Ahn, HS; Allen, GS; Battye, R; Bertsch, LA; Boisvert, DP; Boone, SC; Chou, SN; Crabbe, RA; Dorsey, FC; Hundley, MB; Ingram, CR; Johnson, RK; Kelly, DL; Lavik, PJ; Mellits, DE; Preziosi, TJ; Rosenbloom, SB; Strom, JA; Transou, CR; Weir, BK, 1983) |
| "The authors report findings from a metaanalysis of all published randomized trials of prophylactic nimodipine used in patients who have experienced subarachnoid hemorrhage (SAH)." | 4.79 | Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: a metaanalysis. ( Barker, FG; Ogilvy, CS, 1996) |
| " He was treated with oral nimodipine (30 mg every 8 hours), which alleviated the headache and prevented its recurrence." | 3.79 | Orgasmic headache treated with nimodipine. ( Ha, YS; Lee, HS; Lee, JW; Park, SC; Seo, IY, 2013) |
| "We sought to determine the effects of two different calcium channel antagonists, S-emopamil and nimodipine, on hippocampal glutamate and glycine release and to compare their effects to those of mild hypothermia." | 3.68 | Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits. ( Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH, 1993) |
| "Intravenous Nimodipine was administered to 109 patients (65 female and 44 male) with either pre- or post-operative progressive neurological deterioration from cerebral vasospasm following subarachnoid hemorrhage from a ruptured aneurysm." | 3.67 | Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study. ( Auer, LM; Böker, DK; Gaab, M; Jaksche, H; Koos, WT; Kostron, H; Meinig, G; Muizelaar, JP; Perneczky, A; van der Werf, AJ, 1985) |
| "Here we describe a patient with a thunderclap headache and a mid-basilar narrowing due to a reversible vasospasm." | 1.33 | [Idiopathic thunderclap headache: reversible vasospasm of the Arteria basilaris]. ( Bruening, R; Plendl, H; Straube, A, 2006) |
| "Nimodipine treatment was associated with a significant increase of survival (11." | 1.29 | [Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve]. ( Bazin, A; Bernard, MH; Bertault, R; Gomis, P; Graftieaux, JP; Peruzzi, P; Rousseaux, P; Scherpereel, B, 1993) |
| " When the calcium antagonist nimodipine was given at a dosage quickly escalated to 360 mg daily, the patient could be discharged in a state of complete remission after 26 days." | 1.29 | [Phase prevention in bipolar affective disorder with nimodipine. A case report]. ( Berger, M; Hellwig, B; Hesslinger, B; Riedel, H; Walden, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JW | 1 |
| Ha, YS | 1 |
| Park, SC | 1 |
| Seo, IY | 1 |
| Lee, HS | 1 |
| Zheng, YM | 1 |
| Xie, CH | 1 |
| Gong, FQ | 1 |
| Beccia, M | 1 |
| Ceschin, V | 1 |
| Bozzao, A | 1 |
| Romano, A | 1 |
| Biraschi, F | 1 |
| Fantozzi, LM | 1 |
| Rasura, M | 1 |
| Nanda, S | 1 |
| Agarwal, U | 1 |
| Sangwan, K | 1 |
| Straube, A | 1 |
| Plendl, H | 1 |
| Bruening, R | 1 |
| Allen, GS | 2 |
| Ahn, HS | 1 |
| Preziosi, TJ | 1 |
| Battye, R | 1 |
| Boone, SC | 2 |
| Chou, SN | 1 |
| Kelly, DL | 1 |
| Weir, BK | 1 |
| Crabbe, RA | 1 |
| Lavik, PJ | 1 |
| Rosenbloom, SB | 1 |
| Dorsey, FC | 1 |
| Ingram, CR | 1 |
| Mellits, DE | 1 |
| Bertsch, LA | 1 |
| Boisvert, DP | 1 |
| Hundley, MB | 1 |
| Johnson, RK | 1 |
| Strom, JA | 1 |
| Transou, CR | 1 |
| Pickard, JD | 2 |
| Walker, V | 1 |
| Brandt, L | 1 |
| Zygmunt, S | 1 |
| Smythe, J | 1 |
| Steiger, HJ | 1 |
| Fritschi, J | 1 |
| Seiler, RW | 1 |
| Matsumoto, M | 1 |
| Scheller, MS | 1 |
| Zornow, MH | 1 |
| Strnat, MA | 1 |
| Pazzaglia, PJ | 1 |
| Post, RM | 1 |
| Ketter, TA | 1 |
| George, MS | 1 |
| Marangell, LB | 1 |
| Rousseaux, P | 1 |
| Gomis, P | 1 |
| Bazin, A | 1 |
| Peruzzi, P | 1 |
| Scherpereel, B | 1 |
| Bernard, MH | 1 |
| Bertault, R | 1 |
| Graftieaux, JP | 1 |
| Barker, FG | 1 |
| Ogilvy, CS | 1 |
| Hesslinger, B | 1 |
| Riedel, H | 1 |
| Hellwig, B | 1 |
| Walden, J | 1 |
| Berger, M | 1 |
| Goodnick, PJ | 1 |
| Pianese, CP | 1 |
| Hidalgo, LO | 1 |
| González, RH | 1 |
| Madrid, CE | 1 |
| Ponce, JE | 1 |
| Ramírez, AM | 1 |
| Morán, LM | 1 |
| Arenas, JE | 1 |
| Rubio, AT | 1 |
| Uribe, JO | 1 |
| Abiuso, J | 1 |
| Hanuch, E | 1 |
| Alegría, J | 1 |
| Volpi, C | 1 |
| Flaskamp, R | 1 |
| Sanjuán, AP | 1 |
| Gómez, JM | 1 |
| Hernández, J | 1 |
| Pedraza, A | 1 |
| Quijano, D | 1 |
| Martínez, C | 1 |
| Castañeda, JR | 1 |
| Guerra, OJ | 1 |
| F, GV | 1 |
| Murray, GD | 1 |
| Illingworth, R | 1 |
| Shaw, MD | 1 |
| Teasdale, GM | 1 |
| Foy, PM | 1 |
| Humphrey, PR | 1 |
| Lang, DA | 1 |
| Nelson, R | 1 |
| Richards, P | 1 |
| Ohman, J | 1 |
| Heiskanen, O | 1 |
| Biller, J | 1 |
| Godersky, JC | 1 |
| Adams, HP | 1 |
| Mee, E | 1 |
| Dorrance, D | 1 |
| Lowe, D | 1 |
| Neil-Dwyer, G | 1 |
| Hillman, J | 1 |
| von Essen, C | 1 |
| Leszniewski, W | 1 |
| Johansson, I | 1 |
| Koos, WT | 1 |
| Perneczky, A | 1 |
| Auer, LM | 1 |
| Böker, DK | 1 |
| Gaab, M | 1 |
| Jaksche, H | 1 |
| Kostron, H | 1 |
| Meinig, G | 1 |
| Muizelaar, JP | 1 |
| van der Werf, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Cilostazol-Nimodipine Combined Therapy on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage (aSAH): A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial[NCT04148105] | Phase 4 | 120 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | ||
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| Prevention of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Through Treatment With Intravenous Autologous Cerebrospinal Fluid - a Pilot Trial.[NCT04490161] | 20 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting | |||
| The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study[NCT01996436] | Phase 4 | 330 participants (Anticipated) | Interventional | 2016-08-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nimodipine and Recrudescence
| Article | Year |
|---|---|
Efficacy of prophylactic nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: a metaanalysis.
Topics: Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Humans; Ischemic Attack, Transient; N | 1996 |
Cerebral arterial spasm.
Topics: Blood Platelets; Calcium; Cerebral Arterial Diseases; Humans; Muscle Contraction; Nervous System Dis | 1985 |
6 trials available for nimodipine and Recrudescence
| Article | Year |
|---|---|
Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Fe | 1983 |
Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; | 1993 |
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study.
Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Cinnarizine; Drug Administration Schedule; | 2002 |
Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cerebral Infarction; Clinical Trials as Topic; Do | 1989 |
Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cerebral Infarction; Clinical Trials as Topic; Do | 1989 |
Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cerebral Infarction; Clinical Trials as Topic; Do | 1989 |
Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cerebral Infarction; Clinical Trials as Topic; Do | 1989 |
Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Intracranial Aneurys | 1988 |
Controlled study of nimodipine in aneurysm patients treated early after subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aged; Cardiovascular System; Cerebrovascular Circulation; Clinical Trials as Topi | 1988 |
14 other studies available for nimodipine and Recrudescence
| Article | Year |
|---|---|
Orgasmic headache treated with nimodipine.
Topics: Adult; Calcium Channel Blockers; Cerebral Arteries; Headache; Humans; Magnetic Resonance Angiography | 2013 |
Moyamoya disease associated with aortic coarctation.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aortic Coarctation; Aspirin; Calcium Channel Blocker | 2014 |
Headache and visual symptoms in two patients with MRI alterations in posterior cerebral artery territory.
Topics: Acute Disease; Adult; Aged; Anticoagulants; Clopidogrel; Diagnosis, Differential; Diffusion Magnetic | 2009 |
Successful perinatal outcome following recurrent idiopathic cerebrovascular strokes in pregnancy: a case report.
Topics: Adult; Aspirin; Cerebral Infarction; Delivery, Obstetric; Diagnosis, Differential; Drug Therapy, Com | 2003 |
[Idiopathic thunderclap headache: reversible vasospasm of the Arteria basilaris].
Topics: Adult; Angiography, Digital Subtraction; Cerebral Angiography; Diagnosis, Differential; Headache Dis | 2006 |
Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Brain Damage, Chronic; Cerebral Ventricles; Dexamethasone; Di | 1994 |
Current pattern of in-hospital aneurysmal rebleeds. Analysis of a series treated with individually timed surgery and intravenous nimodipine.
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Neurologi | 1994 |
Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Glutamates; Glutamic Acid; Hippocampus; Hypotherm | 1993 |
[Comparison of 2 consecutive series of aneurysmal subarachnoid hemorrhage with or without nimodipine and study of the temperature curve].
Topics: Adult; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Nimodip | 1993 |
[Phase prevention in bipolar affective disorder with nimodipine. A case report].
Topics: Bipolar Disorder; Calcium Channel Blockers; Depressive Disorder; Dose-Response Relationship, Drug; D | 1996 |
The use of nimodipine in the treatment of mood disorders.
Topics: Activity Cycles; Bipolar Disorder; Calcium Channel Blockers; Catecholamines; Humans; Mood Disorders; | 2000 |
Management of aneurysmal subarachnoid hemorrhage.
Topics: Aminocaproic Acid; Humans; Intracranial Aneurysm; Nervous System Diseases; Nicardipine; Nimodipine; | 1988 |
Significance of "ultra-early" rebleeding in subarachnoid hemorrhage.
Topics: Female; Hematoma; Humans; Intracranial Aneurysm; Male; Mental Disorders; Middle Aged; Nervous System | 1988 |
Nimodipine treatment of ischemic neurological deficits due to cerebral vasospasm after subarachnoid hemorrhage. Clinical results of a multicenter study.
Topics: Adult; Aged; Brain Ischemia; Drug Interactions; Female; Humans; Intracranial Aneurysm; Ischemic Atta | 1985 |