nimodipine has been researched along with Pituitary Neoplasms in 12 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maitotoxin (MTX) is a water-soluble polyether, isolated from the marine dinoflagellate Gambierdiscus toxicus, that stimulates hormone release and Ca2+ influx." | 1.28 | Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels. ( Ramsdell, JS; Van Dolah, FM; Xi, D, 1992) |
| "Pretreatment with thapsigargin blocked the ability of TRH to cause a transient increase in both [Ca2+]c and 45Ca2+ efflux." | 1.28 | Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells. ( Dannies, PS; Hanley, MR; Law, GJ; Pachter, JA; Thastrup, O, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enyeart, JJ | 3 |
| Hinkle, PM | 5 |
| Shipston, MJ | 1 |
| Hernando, F | 1 |
| Barnard, RJ | 1 |
| Antoni, FA | 1 |
| Nilsson, CL | 1 |
| Eriksson, E | 1 |
| Levitan, ES | 1 |
| Gealy, R | 1 |
| Trimmer, JS | 1 |
| Takimoto, K | 1 |
| Pérez, FR | 1 |
| Camiña, JP | 1 |
| Zugaza, JL | 1 |
| Lage, M | 1 |
| Casabiell, X | 1 |
| Casanueva, FF | 1 |
| Li, P | 1 |
| Thaw, CN | 1 |
| Sempowski, GD | 1 |
| Gershengorn, MC | 1 |
| Shanshala, ED | 1 |
| Nelson, EJ | 1 |
| Xi, D | 1 |
| Van Dolah, FM | 1 |
| Ramsdell, JS | 1 |
| Law, GJ | 1 |
| Pachter, JA | 1 |
| Thastrup, O | 1 |
| Hanley, MR | 1 |
| Dannies, PS | 1 |
| Richardson, UI | 1 |
| Sheu, SS | 1 |
| Aizawa, T | 1 |
12 other studies available for nimodipine and Pituitary Neoplasms
| Article | Year |
|---|---|
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Glucocorticoid negative feedback in pituitary corticotropes. Pivotal role for calcineurin inhibition of adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcineurin; Calcium; | 1994 |
Effects of remoxipride and raclopride on prolactin release from clonal pituitary tumour cells.
Topics: Animals; Calcium Channel Blockers; Clone Cells; Dopamine Agonists; Dopamine Antagonists; Ergolines; | 1995 |
Membrane depolarization inhibits Kv1.5 voltage-gated K+ channel gene transcription and protein expression in pituitary cells.
Topics: Amiloride; Animals; Calcium; Clone Cells; Down-Regulation; Gene Expression; Kv1.5 Potassium Channel; | 1995 |
cis-FFA do not alter membrane depolarization but block Ca2+ influx and GH secretion in KCl-stimulated somatotroph cells. Suggestion for a direct cis-FFA perturbation of the Ca2+ channel opening.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Ethanol; Fatty Acids, Nonesterified; Fatty Acid | 1997 |
Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Measurement of intracellular cadmium with fluorescent dyes. Further evidence for the role of calcium channels in cadmium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels.
Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Choline; Dose-Response Relationship, Drug; Isradi | 1992 |
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Multiple classes of calcium channels in mouse pituitary tumor cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Membrane; Clone Cells; Cobalt; Corticotropin-Rel | 1986 |
Dihydropyridine modulators of voltage-sensitive Ca2+ channels specifically regulate prolactin production by GH4C1 pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells.
Topics: Animals; Calcium Channel Blockers; Cell Line; Growth Hormone; Nicotinic Acids; Nifedipine; Nimodipin | 1985 |