nimodipine has been researched along with Pheochromocytoma in 2 studies
Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The uptake and toxicity of cadmium were compared in two rat pheochromocytoma cell lines: PC12 cells, which express voltage-sensitive calcium channels, and PC18 cells, which do not." | 7.69 | Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake. ( Hinkle, PM; Osborne, ME, 1994) |
| "The uptake and toxicity of cadmium were compared in two rat pheochromocytoma cell lines: PC12 cells, which express voltage-sensitive calcium channels, and PC18 cells, which do not." | 3.69 | Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake. ( Hinkle, PM; Osborne, ME, 1994) |
| "The mechanism of calcium channel antagonism by phenytoin was studied by comparing the effects of phenytoin and classical calcium channel antagonists on K+-stimulated 45Ca uptake and [3H]nitrendipine binding in the PC12 pheochromocytoma cell line." | 3.67 | Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. ( Carpenter, CL; Greenberg, DA; Messing, RO, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hinkle, PM | 1 |
| Osborne, ME | 1 |
| Messing, RO | 1 |
| Carpenter, CL | 1 |
| Greenberg, DA | 1 |
2 other studies available for nimodipine and Pheochromocytoma
| Article | Year |
|---|---|
Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell | 1985 |