Page last updated: 2024-11-01

nimodipine and Peripheral Nerve Diseases

nimodipine has been researched along with Peripheral Nerve Diseases in 3 studies

Nimodipine: A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
nimodipine : A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.

Research Excerpts

ExcerptRelevanceReference
"Nimodipine is a calcium-channel antagonist that has provided protection from cisplatin-induced neurotoxicity in a rat model system."2.69Clinical trials of nimodipine as a potential neuroprotector in ovarian cancer patients treated with cisplatin. ( Cassidy, J; Habeshaw, T; Kaye, SB; Parkin, D; Paul, J; Reed, NS; Soukop, M, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Cassidy, J1
Paul, J1
Soukop, M1
Habeshaw, T1
Reed, NS1
Parkin, D1
Kaye, SB1
Hamers, FP1
van der Hoop, RG1
Steerenburg, PA1
Neijt, JP1
Gispen, WH1

Reviews

1 review available for nimodipine and Peripheral Nerve Diseases

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010

Trials

1 trial available for nimodipine and Peripheral Nerve Diseases

ArticleYear
Clinical trials of nimodipine as a potential neuroprotector in ovarian cancer patients treated with cisplatin.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Calcium Channel Blockers; Cisplatin; Double-Blind Method; Drug A

1998

Other Studies

1 other study available for nimodipine and Peripheral Nerve Diseases

ArticleYear
Putative neurotrophic factors in the protection of cisplatin-induced peripheral neuropathy in rats.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Cisplatin; Electrophysiology; Female; Neural Conduction; Nimod

1991